Oncotarget

Vol 7, No 15

April 12, 2016

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Age related increase in mTOR activity contributes to the pathological changes in ovarian surface epithelium. See Bajwa et al.

Table of Contents

Editorial

Nectin-1 and HVEM: cellular receptors for HSV-1 in skin

Nectin-1 and HVEM: cellular receptors for HSV-1 in skin

https://doi.org/10.18632/oncotarget.8340

Dagmar Knebel-Mörsdorf
19087-19088
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Research Papers: Gerotarget (Focus on Aging)

Common DNA methylation alterations of Alzheimer’s disease and aging in peripheral whole blood

Common DNA methylation alterations of Alzheimer’s disease and aging in peripheral whole blood

https://doi.org/10.18632/oncotarget.7862

Hongdong Li, Zheng Guo, You Guo, Mengyao Li, Haidan Yan, Jun Cheng, Chenguang Wang,  and Guini Hong
19089-19098
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RNA methyltransferase NSUN2 promotes stress-induced HUVEC senescence

RNA methyltransferase NSUN2 promotes stress-induced HUVEC senescence

https://doi.org/10.18632/oncotarget.8087

Xiaoyu Cai, Yuanyuan Hu, Hao Tang, Han Hu, Lijun Pang, Junyue Xing, Zhenyun Liu, Yuhong Luo, Bin Jiang, Te Liu, Myriam Gorospe, Chuan Chen,  and Wengong Wang
19099-19110
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Dopamine D2 gene expression interacts with environmental enrichment to impact lifespan and behavior

Dopamine D2 gene expression interacts with environmental enrichment to impact lifespan and behavior

https://doi.org/10.18632/oncotarget.8088

Panayotis K. Thanos, John Hamilton, Joseph R. O’Rourke, Anthony Napoli, Marcelo Febo, Nora D. Volkow, Kenneth Blum,  and Mark Gold
19111-19123
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Safety of two-year caloric restriction in non-obese healthy individuals

Safety of two-year caloric restriction in non-obese healthy individuals

https://doi.org/10.18632/oncotarget.8093

Sergei V. Romashkan, Sai Krupa Das, Dennis T. Villareal, Eric Ravussin, Leanne M. Redman, James Rochon, Manjushri Bhapkar, William E. Kraus,  and for the CALERIE Study Group
19124-19133
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BAF180 regulates cellular senescence and hematopoietic stem cell homeostasis through p21

BAF180 regulates cellular senescence and hematopoietic stem cell homeostasis through p21

https://doi.org/10.18632/oncotarget.8102

Hyemin Lee, Fangyan Dai, Li Zhuang, Zhen-Dong Xiao, Jongchan Kim, Yilei Zhang, Li Ma, M. James You, Zhong Wang,  and Boyi Gan
19134-19146
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The effects of graded levels of calorie restriction: V. Impact of short term calorie and protein restriction on physical activity in the C57BL/6 mouse

The effects of graded levels of calorie restriction: V. Impact of short term calorie and protein restriction on physical activity in the C57BL/6 mouse

https://doi.org/10.18632/oncotarget.8158

Sharon E. Mitchell, Camille Delville, Penelope Konstantopedos, Davina Derous, Cara L. Green, Yingchun Wang, Jing-Dong J. Han, Daniel E.L. Promislow, Alex Douglas, Luonan Chen, David Lusseau,  and John R. Speakman
19147-19170
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MicroRNA signatures in vitreous humour and plasma of patients with exudative AMD

MicroRNA signatures in vitreous humour and plasma of patients with exudative AMD

https://doi.org/10.18632/oncotarget.8280

Catherine Ménard, Flavio A. Rezende, Khalil Miloudi, Ariel Wilson, Nicolas Tétreault, Pierre Hardy, John Paul SanGiovanni, Vincent De Guire,  and Przemyslaw Sapieha
19171-19184
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Towards understanding the lifespan extension by reduced insulin signaling: bioinformatics analysis of DAF-16/FOXO direct targets in Caenorhabditis elegans

Towards understanding the lifespan extension by reduced insulin signaling: bioinformatics analysis of DAF-16/FOXO direct targets in Caenorhabditis elegans

https://doi.org/10.18632/oncotarget.8313

Yan-Hui Li,  and Gai-Gai Zhang
19185-19192
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Olfactory phenotypic expression unveils human aging

Olfactory phenotypic expression unveils human aging

https://doi.org/10.18632/oncotarget.8393

Andrea Mazzatenta, Alessandro Cellerino, Nicola Origlia, Davide Barloscio, Ferdinando Sartucci, Camillo Di Giulio,  and Luciano Domenici
19193-19200
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Curcumin elevates sirtuin level but does not postpone in vitro senescence of human cells building the vasculature

Curcumin elevates sirtuin level but does not postpone in vitro senescence of human cells building the vasculature

https://doi.org/10.18632/oncotarget.8450

Wioleta Grabowska, Małgorzata Suszek, Maciej Wnuk, Anna Lewinska, Emilia Wasiak, Ewa Sikora,  and Anna Bielak-Zmijewska
19201-19213
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Age related increase in mTOR activity contributes to the pathological changes in ovarian surface epithelium

Age related increase in mTOR activity contributes to the pathological changes in ovarian surface epithelium

https://doi.org/10.18632/oncotarget.8468

Preety Bajwa, Prathima B. Nagendra, Sarah Nielsen, Subhransu S. Sahoo, Amanda Bielanowicz, Janine M. Lombard, J. Erby Wilkinson, Richard A. Miller,  and Pradeep S. Tanwar
19214-19227
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Methylomic predictors demonstrate the role of NF-κB in old-age mortality and are unrelated to the aging-associated epigenetic drift

Methylomic predictors demonstrate the role of NF-κB in old-age mortality and are unrelated to the aging-associated epigenetic drift

https://doi.org/10.18632/oncotarget.8278

Juulia Jylhävä, Laura Kananen, Jani Raitanen, Saara Marttila, Tapio Nevalainen, Antti Hervonen, Marja Jylhä,  and Mikko Hurme
19228-19241
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Research Papers: Pathology

Cellular evidence for nano-scale exosome secretion and interactions with spermatozoa in the epididymis of the Chinese soft-shelled turtle, Pelodiscus sinensis

Cellular evidence for nano-scale exosome secretion and interactions with spermatozoa in the epididymis of the Chinese soft-shelled turtle, Pelodiscus sinensis

https://doi.org/10.18632/oncotarget.8092

Hong Chen, Ping Yang, Xiaoya Chu, Yufei Huang, Tengfei Liu, Qian Zhang, Quanfu Li, Lisi Hu, Yasir Waqas, Nisar Ahmed,  and Qiusheng Chen
19242-19250
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Research Papers: Immunology

CD226 ligation protects against EAE by promoting IL-10 expression via regulation of CD4+ T cell differentiation

CD226 ligation protects against EAE by promoting IL-10 expression via regulation of CD4+ T cell differentiation

https://doi.org/10.18632/oncotarget.7834

Rong Zhang, Hanyu Zeng, Yun Zhang, Kun Chen, Chunmei Zhang, Chaojun Song, Liang Fang, Zhuwei Xu, Kun Yang, Boquan Jin, Qintao Wang,  and Lihua Chen
19251-19264
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Reduced serpinB9-mediated caspase-1 inhibition can contribute to autoinflammatory disease

Reduced serpinB9-mediated caspase-1 inhibition can contribute to autoinflammatory disease

https://doi.org/10.18632/oncotarget.8086

Robert van der Burgh, Jan Meeldijk, Lieneke Jongeneel, Joost Frenkel, Niels Bovenschen, Mariëlle van Gijn,  and Marianne Boes
19265-19271
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Nrf2 plays a pivotal role in protection against burn trauma-induced intestinal injury and death

Nrf2 plays a pivotal role in protection against burn trauma-induced intestinal injury and death

https://doi.org/10.18632/oncotarget.8189

Zhao Chen, Yiran Zhang, Liang Ma, Yiming Ni,  and Haige Zhao
19272-19283
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Ascophyllan functions as an adjuvant to promote anti-cancer effect by dendritic cell activation

Ascophyllan functions as an adjuvant to promote anti-cancer effect by dendritic cell activation

https://doi.org/10.18632/oncotarget.8200

Wei Zhang, Takasi Okimura, Li Xu, Lijun Zhang, Tatsuya Oda, Minseok Kwak, Qing Yu,  and Jun-O Jin
19284-19298
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B1a cells play a pathogenic role in the development of autoimmune arthritis

B1a cells play a pathogenic role in the development of autoimmune arthritis

https://doi.org/10.18632/oncotarget.8244

Jun Deng, Xiaohui Wang, Qian Chen, Xiaoxuan Sun, Fan Xiao, King-Hung Ko, Miaojia Zhang,  and Liwei Lu
19299-19311
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5-Fluorouracil targets thymidylate synthase in the selective suppression of TH17 cell differentiation

5-Fluorouracil targets thymidylate synthase in the selective suppression of TH17 cell differentiation

https://doi.org/10.18632/oncotarget.8344

Juan Wang, Liang Peng, Ruihua Zhang, Zihan Zheng, Chun Chen, Ka Lung Cheung, Miao Cui, Guanglin Bian, Feihong Xu, David Chiang, Yuan Hu, Ye Chen, Geming Lu, Jianjun Yang, Hui Zhang, Jianfei Yang, Hongfa Zhu, Shu-hsia Chen, Kebin Liu, Ming-Ming Zhou, Andrew G. Sikora, Liwu Li, Bo Jiang,  and Huabao Xiong
19312-19326
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Capsules of virulent pneumococcal serotypes enhance formation of neutrophil extracellular traps during in vivo pathogenesis of pneumonia

Capsules of virulent pneumococcal serotypes enhance formation of neutrophil extracellular traps during in vivo pathogenesis of pneumonia

https://doi.org/10.18632/oncotarget.8451

Anandi Narayana Moorthy, Prashant Rai, Huipeng Jiao, Shi Wang, Kong Bing Tan, Liang Qin, Hiroshi Watanabe, Yongliang Zhang, Teluguakula Narasaraju,  and Vincent Tak Kwong Chow
19327-19340
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Development of interleukin-17-producing Vγ2+ γδ T cells is reduced by ICOS signaling in the thymus

Development of interleukin-17-producing Vγ2+ γδ T cells is reduced by ICOS signaling in the thymus

https://doi.org/10.18632/oncotarget.8464

Terkild Brink Buus, Jonas Damgård Schmidt, Charlotte Menné Bonefeld, Carsten Geisler,  and Jens Peter Holst Lauritsen
19341-19354
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Distinctly altered gut microbiota in the progression of liver disease

Distinctly altered gut microbiota in the progression of liver disease

https://doi.org/10.18632/oncotarget.8466

Guoxiang Xie, Xiaoning Wang, Ping Liu, Runmin Wei, Wenlian Chen, Cynthia Rajani, Brenda Y. Hernandez, Rosanna Alegado, Bing Dong, Defa Li,  and Wei Jia
19355-19366
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Research Papers: Autophagy and Cell Death

Necrostatin-1 enhances the resolution of inflammation by specifically inducing neutrophil apoptosis

Necrostatin-1 enhances the resolution of inflammation by specifically inducing neutrophil apoptosis

https://doi.org/10.18632/oncotarget.8346

Hongyu Jie, Yi He, Xuechan Huang, Qingyou Zhou, Yanping Han, Xing Li, Yongkun Bai,  and Erwei Sun
19367-19381
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C3 deficiency ameliorates the negative effects of irradiation of the young brain on hippocampal development and learning

C3 deficiency ameliorates the negative effects of irradiation of the young brain on hippocampal development and learning

https://doi.org/10.18632/oncotarget.8400

Marie Kalm, Ulf Andreasson, Thomas Björk-Eriksson, Henrik Zetterberg, Milos Pekny, Kaj Blennow, Marcela Pekna,  and Klas Blomgren
19382-19394
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Reviews

The role of N-glycans in colorectal cancer progression: potential biomarkers and therapeutic applications

The role of N-glycans in colorectal cancer progression: potential biomarkers and therapeutic applications

https://doi.org/10.18632/oncotarget.6283

Julio Cesar Madureira de Freitas Junior,  and José Andrés Morgado-Díaz
19395-19413
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The cytoskeletal arrangements necessary to neurogenesis

The cytoskeletal arrangements necessary to neurogenesis

https://doi.org/10.18632/oncotarget.6838

Claudia Compagnucci, Fiorella Piemonte, Antonella Sferra, Emanuela Piermarini,  and Enrico Bertini
19414-19429
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Amyloid precursor protein and amyloid precursor-like protein 2 in cancer

Amyloid precursor protein and amyloid precursor-like protein 2 in cancer

https://doi.org/10.18632/oncotarget.7103

Poomy Pandey, Bailee Sliker, Haley L. Peters, Amit Tuli, Jonathan Herskovitz, Kaitlin Smits, Abhilasha Purohit, Rakesh K. Singh, Jixin Dong, Surinder K. Batra, Donald W. Coulter,  and Joyce C. Solheim
19430-19444
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Research Papers

The CNGRC-GG-D(KLAKLAK)2 peptide induces a caspase-independent, Ca2+-dependent death in human leukemic myeloid cells by targeting surface aminopeptidase N/CD13

The CNGRC-GG-D(KLAKLAK)2 peptide induces a caspase-independent, Ca2+-dependent death in human leukemic myeloid cells by targeting surface aminopeptidase N/CD13

https://doi.org/10.18632/oncotarget.6523

Sandrine Bouchet, Ruoping Tang, Fanny Fava, Ollivier Legrand,  and Brigitte Bauvois
19445-19467
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Bile acid-FXRα pathways regulate male sexual maturation in mice

Bile acid-FXRα pathways regulate male sexual maturation in mice

https://doi.org/10.18632/oncotarget.7153

Marine Baptissart, Emmanuelle Martinot, Aurélie Vega, Lauriane Sédes, Betty Rouaisnel, Angélique de Haze, Silvère Baron, Kristina Schoonjans, Françoise Caira,  and David H. Volle
19468-19482
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Interplay between PCBP2 and miRNA modulates ARHGDIA expression and function in glioma migration and invasion

Interplay between PCBP2 and miRNA modulates ARHGDIA expression and function in glioma migration and invasion

https://doi.org/10.18632/oncotarget.6869

Xihua Lin, Bin Yang, Wei Liu, Xiaochao Tan, Fan Wu, Peishan Hu, Tao Jiang, Zhaoshi Bao, Jiangang Yuan, Boqin Qiang, Xiaozhong Peng,  and Wei Han
19483-19498
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

TGF-β1 and TGF-β2 abundance in liver diseases of mice and men

TGF-β1 and TGF-β2 abundance in liver diseases of mice and men

https://doi.org/10.18632/oncotarget.6967

Anne Dropmann, Tatjana Dediulia, Katja Breitkopf-Heinlein, Hanna Korhonen, Michel Janicot, Susanne N. Weber, Maria Thomas, Albrecht Piiper, Esther Bertran, Isabel Fabregat, Kerstin Abshagen, Jochen Hess, Peter Angel, Cédric Coulouarn, Steven Dooley,  and Nadja M. Meindl-Beinker
19499-19518
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Tumor suppressor role of microRNA-1296 in triple-negative breast cancer

Tumor suppressor role of microRNA-1296 in triple-negative breast cancer

https://doi.org/10.18632/oncotarget.6961

Binh Phan, Shahana Majid, Sarah Ursu, David de Semir, Mehdi Nosrati, Vladimir Bezrookove, Mohammed Kashani-Sabet,  and Altaf A. Dar
19519-19530
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miR-340 predicts glioblastoma survival and modulates key cancer hallmarks through down-regulation of NRAS

miR-340 predicts glioblastoma survival and modulates key cancer hallmarks through down-regulation of NRAS

https://doi.org/10.18632/oncotarget.6968

Danilo Fiore, Elvira Donnarumma, Giuseppina Roscigno, Margherita Iaboni, Valentina Russo, Alessandra Affinito, Assunta Adamo, Fabio De Martino, Cristina Quintavalle, Giulia Romano, Adelaide Greco, Ylermi Soini, Arturo Brunetti, Carlo M. Croce,  and Gerolama Condorelli
19531-19547
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Macrophage targeting contributes to the inhibitory effects of embelin on colitis-associated cancer

Macrophage targeting contributes to the inhibitory effects of embelin on colitis-associated cancer

https://doi.org/10.18632/oncotarget.6969

Ting Wu, Yun Dai, Weihong Wang, Guigen Teng, Hongmei Jiao, Xiaowei Shuai, Rongxin Zhang, Peng Zhao,  and Liang Qiao
19548-19558
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Synergistic antitumor activity of histone deacetylase inhibitors and anti-ErbB3 antibody in NSCLC primary cultures via modulation of ErbB receptors expression

Synergistic antitumor activity of histone deacetylase inhibitors and anti-ErbB3 antibody in NSCLC primary cultures via modulation of ErbB receptors expression

https://doi.org/10.18632/oncotarget.7195

Chiara Ciardiello, Maria Serena Roca, Alessia Noto, Francesca Bruzzese, Tania Moccia, Carlo Vitagliano, Elena Di Gennaro, Gennaro Ciliberto, Giuseppe Roscilli, Luigi Aurisicchio, Emanuele Marra, Rita Mancini, Alfredo Budillon,  and Alessandra Leone
19559-19574
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Use of genetically encoded, light-gated ion translocators to control tumorigenesis

Use of genetically encoded, light-gated ion translocators to control tumorigenesis

https://doi.org/10.18632/oncotarget.8036

Brook T. Chernet, Dany S. Adams, Maria Lobikin,  and Michael Levin
19575-19588
Abstract  |  PDF  |  HTML  |  Order a Reprint

Serum high expression of miR-214 and miR-135b as novel predictor for myeloma bone disease development and prognosis

Serum high expression of miR-214 and miR-135b as novel predictor for myeloma bone disease development and prognosis

https://doi.org/10.18632/oncotarget.7319

Mu Hao, Meirong Zang, Lei Zhao, Shuhui Deng, Yan Xu, Fang Qi, Gang An, Yu Qin, Weiwei Sui, Fei Li, Wenjuan Yang, Zengjun Li, Shuhua Yi, Dehui Zou, Fenghuang Zhan,  and Lugui Qiu
19589-19600
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

MicroRNA expression profiles of drug-resistance breast cancer cells and their exosomes

MicroRNA expression profiles of drug-resistance breast cancer cells and their exosomes

https://doi.org/10.18632/oncotarget.7481

Shanliang Zhong, Xiu Chen, Dandan Wang, Xiaohui Zhang, Hongyu Shen, Sujin Yang, Mengmeng Lv, Jinhai Tang,  and Jianhua Zhao
19601-19609
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Molecular characterization of colorectal cancer patients and concomitant patient-derived tumor cell establishment

Molecular characterization of colorectal cancer patients and concomitant patient-derived tumor cell establishment

https://doi.org/10.18632/oncotarget.7526

Haa-Na Song, Chung Lee, Seung Tae Kim, Sun Young Kim, Nayoung K.D. Kim, Jiryeon Jang, Mihyun Kang, Hyojin Jang, Soomin Ahn, Seok Hyeong Kim, Yoona Park, Yong Beom Cho, Jeong Wook Heo, Woo Yong Lee, Joon Oh Park, Ho Yeong Lim, Won Ki Kang, Young Suk Park, Woong-Yang Park, Jeeyun Lee,  and Hee Cheol Kim
19610-19619
Abstract  |  PDF  |  HTML  |  Order a Reprint

The afatinib resistance of in vivo generated H1975 lung cancer cell clones is mediated by SRC/ERBB3/c-KIT/c-MET compensatory survival signaling

The afatinib resistance of in vivo generated H1975 lung cancer cell clones is mediated by SRC/ERBB3/c-KIT/c-MET compensatory survival signaling

https://doi.org/10.18632/oncotarget.7746

Laurence Booth, Jane L. Roberts, Mehrad Tavallai, Timothy Webb, Daniel Leon, Jesse Chen, William P. McGuire, Andrew Poklepovic,  and Paul Dent
19620-19630
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Ezrin contributes to cervical cancer progression through induction of epithelial-mesenchymal transition

Ezrin contributes to cervical cancer progression through induction of epithelial-mesenchymal transition

https://doi.org/10.18632/oncotarget.7779

Jienan Kong, Chunchan Di, Junjie Piao, Jie Sun, Longzhe Han, Liyan Chen, Guanghai Yan,  and Zhenhua Lin
19631-19642
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Impact of age on efficacy of postoperative oxaliplatin-based chemotherapy in patients with rectal cancer after neoadjuvant chemoradiotherapy

Impact of age on efficacy of postoperative oxaliplatin-based chemotherapy in patients with rectal cancer after neoadjuvant chemoradiotherapy

https://doi.org/10.18632/oncotarget.7544

Xuan-zhang Huang, Peng Gao, Yong-xi Song, Jing-xu Sun, Xiao-wan Chen, Jun-hua Zhao, Bin Ma, Jun Wang,  and Zhen-ning Wang
19643-19653
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Parotid area lymph node metastases from preliminarily diagnosed patients with nasopharyngeal carcinoma: report on tumor characteristics and oncologic outcomes

Parotid area lymph node metastases from preliminarily diagnosed patients with nasopharyngeal carcinoma: report on tumor characteristics and oncologic outcomes

https://doi.org/10.18632/oncotarget.7677

Yuanji Xu, Mingwei Zhang, Youping Xiao, Jingfeng Zong, Sufang Qiu, Penggang Bai, Yitao Dai, Lin Zhou, Xiaolin Chen, Wei Zheng, Yunbin Chen, Shaojun Lin,  and Jianji Pan
19654-19665
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MicroRNA-27b up-regulated by human papillomavirus 16 E7 promotes proliferation and suppresses apoptosis by targeting polo-like kinase2 in cervical cancer

MicroRNA-27b up-regulated by human papillomavirus 16 E7 promotes proliferation and suppresses apoptosis by targeting polo-like kinase2 in cervical cancer

https://doi.org/10.18632/oncotarget.7531

Fei Liu, Shimeng Zhang, Zhen Zhao, Xinru Mao, Jinlan Huang, Zixian Wu, Lei Zheng,  and Qian Wang
19666-19679
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

High expression of Zinc-finger protein X-linked promotes tumor growth and predicts a poor outcome for stage II/III colorectal cancer patients

High expression of Zinc-finger protein X-linked promotes tumor growth and predicts a poor outcome for stage II/III colorectal cancer patients

https://doi.org/10.18632/oncotarget.7547

Xuebing Yan, Zezhi Shan, Leilei Yan, Qingchao Zhu, Liguo Liu, Bing Xu, Sihong Liu, Zhiming Jin,  and Yuping Gao
19680-19692
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Histone deacetylase 9 regulates breast cancer cell proliferation and the response to histone deacetylase inhibitors

Histone deacetylase 9 regulates breast cancer cell proliferation and the response to histone deacetylase inhibitors

https://doi.org/10.18632/oncotarget.7564

Marion Lapierre, Aurélien Linares, Mathieu Dalvai, Céline Duraffourd, Sandrine Bonnet, Abdelhay Boulahtouf, Carmen Rodriguez, Stéphan Jalaguier, Said Assou, Beatrice Orsetti, Patrick Balaguer, Thierry Maudelonde, Philippe Blache, Kerstin Bystricky, Nathalie Boulle,  and Vincent Cavaillès
19693-19708
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Oncogenic epithelial cell-derived exosomes containing Rac1 and PAK2 induce angiogenesis in recipient endothelial cells

Oncogenic epithelial cell-derived exosomes containing Rac1 and PAK2 induce angiogenesis in recipient endothelial cells

https://doi.org/10.18632/oncotarget.7573

Shashi K. Gopal, David W. Greening, Eric G. Hanssen, Hong-Jian Zhu, Richard J. Simpson,  and Rommel A. Mathias
19709-19722
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Downregulation of miR-137 and miR-6500-3p promotes cell proliferation in pediatric high-grade gliomas

Downregulation of miR-137 and miR-6500-3p promotes cell proliferation in pediatric high-grade gliomas

https://doi.org/10.18632/oncotarget.7736

Muh-Lii Liang, Tsung-Han Hsieh, Kim-Hai Ng, Ya-Ni Tsai, Cheng-Fong Tsai, Meng-En Chao, Da-Jung Liu, Shing-Shiung Chu, Wan Chen, Yun-Ru Liu, Ren-Shyan Liu, Shih-Chieh Lin, Donald Ming-Tak Ho, Tai-Tong Wong, Muh-Hwa Yang,  and Hsei-Wei Wang
19723-19737
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

PD-L1 expression as predictive biomarker in patients with NSCLC: a pooled analysis

PD-L1 expression as predictive biomarker in patients with NSCLC: a pooled analysis

https://doi.org/10.18632/oncotarget.7582

Francesco Passiglia, Giuseppe Bronte, Viviana Bazan, Clara Natoli, Sergio Rizzo, Antonio Galvano, Angela Listì, Giuseppe Cicero, Christian Rolfo, Daniele Santini,  and Antonio Russo
19738-19747
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Fibroblast growth factor receptor 2 expression, but not its genetic amplification, is associated with tumor growth and worse survival in esophagogastric junction adenocarcinoma

Fibroblast growth factor receptor 2 expression, but not its genetic amplification, is associated with tumor growth and worse survival in esophagogastric junction adenocarcinoma

https://doi.org/10.18632/oncotarget.7782

Ryuma Tokunaga, Yu Imamura, Kenichi Nakamura, Takatsugu Ishimoto, Shigeki Nakagawa, Keisuke Miyake, Yu Nakaji, Yasuo Tsuda, Masaaki Iwatsuki, Yoshifumi Baba, Yasuo Sakamoto, Yuji Miyamoto, Hiroshi Saeki, Naoya Yoshida, Eiji Oki, Masayuki Watanabe, Yoshinao Oda, Adam J. Bass, Yoshihiko Maehara,  and Hideo Baba
19748-19761
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Multiparametric monitoring of chemotherapy treatment response in locally advanced breast cancer using quantitative ultrasound and diffuse optical spectroscopy

Multiparametric monitoring of chemotherapy treatment response in locally advanced breast cancer using quantitative ultrasound and diffuse optical spectroscopy

https://doi.org/10.18632/oncotarget.7844

William T. Tran, Charmaine Childs, Lee Chin, Elzbieta Slodkowska, Lakshmanan Sannachi, Hadi Tadayyon, Elyse Watkins, Sharon Lemon Wong, Belinda Curpen, Ahmed El Kaffas, Azza Al-Mahrouki, Ali Sadeghi-Naini,  and Gregory J. Czarnota
19762-19780
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Predictive role of microRNA-related genetic polymorphisms in the pathological complete response to neoadjuvant chemoradiotherapy in locally advanced rectal cancer patients

Predictive role of microRNA-related genetic polymorphisms in the pathological complete response to neoadjuvant chemoradiotherapy in locally advanced rectal cancer patients

https://doi.org/10.18632/oncotarget.7757

Eva Dreussi, Salvatore Pucciarelli, Antonino De Paoli, Jerry Polesel, Vincenzo Canzonieri, Marco Agostini, Maria Luisa Friso, Claudio Belluco, Angela Buonadonna, Sara Lonardi, Chiara Zanusso, Elena De Mattia, Giuseppe Toffoli,  and Erika Cecchin
19781-19793
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

DDA1 promotes stage IIB–IIC colon cancer progression by activating NFκB/CSN2/GSK-3β signaling

DDA1 promotes stage IIB–IIC colon cancer progression by activating NFκB/CSN2/GSK-3β signaling

https://doi.org/10.18632/oncotarget.7847

Senlin Zhao, Huamei Tang, Dongwang Yan, Junwei Fan, Hongcheng Sun, Yugang Wen, Fudong Yu, Feifei Cui, Dongyuan Zhang, Yingming Xue, Chenchen Liu, Ben Yue, Jian Chen, Jingtao Wang, Xiao Wang, Meng Zhang, Yang Yu, Weiliang Jiang, Xisheng Liu, Yushuai Mi, Zongguang Zhou, Xuebin Qin,  and Zhihai Peng
19794-19812
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Decreased level of RASSF6 in sporadic colorectal cancer and its anti-tumor effects both in vitro and in vivo

Decreased level of RASSF6 in sporadic colorectal cancer and its anti-tumor effects both in vitro and in vivo

https://doi.org/10.18632/oncotarget.7852

Erfei Chen, Fangfang Yang, Hongjuan He, Lei Lei, Ruitao Liu, Le Du, Jing Dong, Meng Wang,  and Jin Yang
19813-19823
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Early-phase circulating miRNAs predict tumor recurrence and survival of hepatocellular carcinoma patients after liver transplantation

Early-phase circulating miRNAs predict tumor recurrence and survival of hepatocellular carcinoma patients after liver transplantation

https://doi.org/10.18632/oncotarget.7627

Kevin Tak-Pan NG, Chung Mau Lo, Nathalie Wong, Chang Xian Li, Xiang Qi, Xiao Bing Liu, Wei Geng, Oscar Wai-Ho Yeung, Yuen Yuen Ma, See Ching Chan,  and Kwan Man
19824-19839
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Impact of molecular profiling on overall survival of patients with advanced ovarian cancer

Impact of molecular profiling on overall survival of patients with advanced ovarian cancer

https://doi.org/10.18632/oncotarget.7835

Thomas J. Herzog, David Spetzler, Nick Xiao, Ken Burnett, Todd Maney, Andreas Voss, Sandeep Reddy, Robert Burger, Thomas Krivak, Matthew Powell, Michael Friedlander,  and William McGuire
19840-19849
Abstract  |  PDF  |  HTML  |  Order a Reprint

Environmental exposure and HPV infection may act synergistically to induce lung tumorigenesis in nonsmokers

Environmental exposure and HPV infection may act synergistically to induce lung tumorigenesis in nonsmokers

https://doi.org/10.18632/oncotarget.7628

Ya-Wen Cheng, Frank Cheau-Feng Lin, Chih-Yi Chen,  and Nan-Yung Hsu
19850-19862
Abstract  |  PDF  |  HTML  |  Order a Reprint

Prognostic role of STAT3 in solid tumors: a systematic review and meta-analysis

Prognostic role of STAT3 in solid tumors: a systematic review and meta-analysis

https://doi.org/10.18632/oncotarget.7887

Pin Wu, Dang Wu, Lufeng Zhao, Lijian Huang, Gang Shen, Jian Huang,  and Ying Chai
19863-19883
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

A BRCA1 deficient, NFκB driven immune signal predicts good outcome in triple negative breast cancer

A BRCA1 deficient, NFκB driven immune signal predicts good outcome in triple negative breast cancer

https://doi.org/10.18632/oncotarget.7865

Niamh E. Buckley, Paula Haddock, Ricardo De Matos Simoes, Eileen Parkes, Gareth Irwin, Frank Emmert-Streib, Stephen McQuaid, Richard Kennedy,  and Paul Mullan
19884-19896
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

ZSTK474, a specific class I phosphatidylinositol 3-kinase inhibitor, induces G1 arrest and autophagy in human breast cancer MCF-7 cells

ZSTK474, a specific class I phosphatidylinositol 3-kinase inhibitor, induces G1 arrest and autophagy in human breast cancer MCF-7 cells

https://doi.org/10.18632/oncotarget.7658

Yaochen Wang, Jing Liu, Yuling Qiu, Meihua Jin, Xi Chen, Guanwei Fan, Ran Wang,  and Dexin Kong
19897-19909
Abstract  |  PDF  |  HTML  |  Order a Reprint

Tumor-selective mitochondrial network collapse induced by atmospheric gas plasma-activated medium

Tumor-selective mitochondrial network collapse induced by atmospheric gas plasma-activated medium

https://doi.org/10.18632/oncotarget.7889

Kosuke Saito, Tomohiko Asai, Kyoko Fujiwara, Junki Sahara, Haruhisa Koguchi, Noboru Fukuda, Miki Suzuki-Karasaki, Masayoshi Soma,  and Yoshihiro Suzuki-Karasaki
19910-19927
Abstract  |  PDF  |  HTML  |  Order a Reprint

Genetic variants of lncRNA HOTAIR contribute to the risk of osteosarcoma

Genetic variants of lncRNA HOTAIR contribute to the risk of osteosarcoma

https://doi.org/10.18632/oncotarget.7957

Quan Zhou, Fengli Chen, Zhongting Fei, Jiali Zhao, Yong Liang, Wei Pan, Xingxiang Liu,  and Donghui Zheng
19928-19934
Abstract  |  PDF  |  HTML  |  Order a Reprint

Vascular patterns provide therapeutic targets in aggressive neuroblastic tumors

Vascular patterns provide therapeutic targets in aggressive neuroblastic tumors

https://doi.org/10.18632/oncotarget.7661

Irene Tadeo, Gloria Bueno, Ana P. Berbegall, M. Milagro Fernández-Carrobles, Victoria Castel, Marcial García-Rojo, Samuel Navarro,  and Rosa Noguera
19935-19947
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

High-throughput drug library screening identifies colchicine as a thyroid cancer inhibitor

High-throughput drug library screening identifies colchicine as a thyroid cancer inhibitor

https://doi.org/10.18632/oncotarget.7890

Le Zhang, Zhaoying Yang, Letizia Granieri, Adrian Pasculescu, Alessandro Datti, Sylvia L. Asa, Zheli Xu,  and Shereen Ezzat
19948-19959
Abstract  |  PDF  |  HTML  |  Order a Reprint

Knockdown of long non-coding RNA TP73-AS1 inhibits cell proliferation and induces apoptosis in esophageal squamous cell carcinoma

Knockdown of long non-coding RNA TP73-AS1 inhibits cell proliferation and induces apoptosis in esophageal squamous cell carcinoma

https://doi.org/10.18632/oncotarget.6963

Wenqiao Zang, Tao Wang, Yuanyuan Wang, Xiaonan Chen, Yuwen Du, Qianqian Sun, Min Li, Ziming Dong,  and Guoqiang Zhao
19960-19974
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Expression profile and prognostic value of NNMT in patients with pancreatic cancer

Expression profile and prognostic value of NNMT in patients with pancreatic cancer

https://doi.org/10.18632/oncotarget.7891

Yong Xu, Ping Liu, Dong-Hui Zheng, Nan Wu, Lun Zhu, Changying Xing,  and Jin Zhu
19975-19981
Abstract  |  PDF  |  HTML  |  Order a Reprint

Carnitine palmitoyl transferase-1A (CPT1A): a new tumor specific target in human breast cancer

Carnitine palmitoyl transferase-1A (CPT1A): a new tumor specific target in human breast cancer

https://doi.org/10.18632/oncotarget.6964

Sabina Pucci, Maria Josè Zonetti, Tommaso Fisco, Chiara Polidoro, Gianfranco Bocchinfuso, Antonio Palleschi, Giuseppe Novelli, Luigi G. Spagnoli,  and Paola Mazzarelli
19982-19996
Abstract  |  PDF  |  HTML  |  Order a Reprint

Fibroblast-induced switching to the mesenchymal-like phenotype and PI3K/mTOR signaling protects melanoma cells from BRAF inhibitors

Fibroblast-induced switching to the mesenchymal-like phenotype and PI3K/mTOR signaling protects melanoma cells from BRAF inhibitors

https://doi.org/10.18632/oncotarget.7671

Kotryna Seip, Karianne G. Fleten, Anna Barkovskaya, Vigdis Nygaard, Mads H. Haugen, Birgit Ø. Engesæter, Gunhild M. Mælandsmo,  and Lina Prasmickaite
19997-20015
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Diagnostic and clinical relevance of the autophago-lysosomal network in human gliomas

Diagnostic and clinical relevance of the autophago-lysosomal network in human gliomas

https://doi.org/10.18632/oncotarget.7910

Lukas Jennewein, Michael W. Ronellenfitsch, Patrick Antonietti, Elena I. Ilina, Jennifer Jung, Daniela Stadel, Lisa-Marie Flohr, Jenny Zinke, Janusz von Renesse, Ulrich Drott, Peter Baumgarten, Anne K. Braczynski, Cornelia Penski, Michael C. Burger, Jean-Philippe Theurillat, Joachim P. Steinbach, Karl-Heinz Plate, Ivan Dikic, Simone Fulda, Christian Brandts, Donat Kögel, Christian Behrends, Patrick N. Harter,  and Michel Mittelbronn
20016-20032
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Somatostatin receptor expression in small cell lung cancer as a prognostic marker and a target for peptide receptor radionuclide therapy

Somatostatin receptor expression in small cell lung cancer as a prognostic marker and a target for peptide receptor radionuclide therapy

https://doi.org/10.18632/oncotarget.7706

Constantin Lapa, Heribert Hänscheid, Vanessa Wild, Theo Pelzer, Andreas Schirbel, Rudolf A. Werner, Sabine Droll, Ken Herrmann, Andreas K. Buck,  and Katharina Lückerath
20033-20040
Abstract  |  PDF  |  HTML  |  Order a Reprint

MicroRNA-432 functions as a tumor suppressor gene through targeting E2F3 and AXL in lung adenocarcinoma

MicroRNA-432 functions as a tumor suppressor gene through targeting E2F3 and AXL in lung adenocarcinoma

https://doi.org/10.18632/oncotarget.7884

Ling Chen, Guangming Kong, Chuantao Zhang, Hongyan Dong, Cuicui Yang, Guanhua Song, Chengye Guo, Lin Wang,  and Hongsheng Yu
20041-20053
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Anti-apoptotic ARC protein confers chemoresistance by controlling leukemia-microenvironment interactions through a NFκB/IL1β signaling network

Anti-apoptotic ARC protein confers chemoresistance by controlling leukemia-microenvironment interactions through a NFκB/IL1β signaling network

https://doi.org/10.18632/oncotarget.7911

Bing Z. Carter, Po Yee Mak, Ye Chen, Duncan H. Mak, Hong Mu, Rodrigo Jacamo, Vivian Ruvolo, Stefan T. Arold, John E. Ladbury, Jared K. Burks, Steven Kornblau,  and Michael Andreeff
20054-20067
Abstract  |  PDF  |  HTML  |  Order a Reprint

MicroRNA deregulation in triple negative breast cancer reveals a role of miR-498 in regulating BRCA1 expression

MicroRNA deregulation in triple negative breast cancer reveals a role of miR-498 in regulating BRCA1 expression

https://doi.org/10.18632/oncotarget.7705

Nerea Matamala, Maria Teresa Vargas, Ricardo González-Cámpora, Jose Ignacio Arias, Primitiva Menéndez, Eduardo Andrés-León, Kira Yanowsky, Ana Llaneza-Folgueras, Rebeca Miñambres, Beatriz Martínez-Delgado,  and Javier Benítez
20068-20079
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Antitumor effect of the novel sphingosine kinase 2 inhibitor ABC294640 is enhanced by inhibition of autophagy and by sorafenib in human cholangiocarcinoma cells

Antitumor effect of the novel sphingosine kinase 2 inhibitor ABC294640 is enhanced by inhibition of autophagy and by sorafenib in human cholangiocarcinoma cells

https://doi.org/10.18632/oncotarget.7914

Xiwei Ding, Roongruedee Chaiteerakij, Catherine D. Moser, Hassan Shaleh, Jeffrey Boakye, Gang Chen, Albert Ndzengue, Ying Li, Yanling Zhou, Shengbing Huang, Frank A. Sinicrope, Xiaoping Zou, Melanie B. Thomas, Charles D. Smith,  and Lewis R. Roberts
20080-20092
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Optimized selection of three major EGFR-TKIs in advanced EGFR-positive non-small cell lung cancer: a network meta-analysis

Optimized selection of three major EGFR-TKIs in advanced EGFR-positive non-small cell lung cancer: a network meta-analysis

https://doi.org/10.18632/oncotarget.7713

Yaxiong Zhang, Jin Sheng, Yunpeng Yang, Wenfeng Fang, Shiyang Kang, Yang He, Shaodong Hong, Jianhua Zhan, Yuanyuan Zhao, Cong Xue, Yuxiang Ma, Ting Zhou, Shuxiang Ma, Fangfang Gao, Tao Qin, Zhihuang Hu, Ying Tian, Xue Hou, Yan Huang, Ningning Zhou, Hongyun Zhao,  and Li Zhang
20093-20108
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Biomarkers of evasive resistance predict disease progression in cancer patients treated with antiangiogenic therapies

Biomarkers of evasive resistance predict disease progression in cancer patients treated with antiangiogenic therapies

https://doi.org/10.18632/oncotarget.7915

Andreas Pircher, Karin Jöhrer, Florian Kocher, Normann Steiner, Ivo Graziadei, Isabel Heidegger, Renate Pichler, Nicolai Leonhartsberger, Christian Kremser, Johann Kern, Gerold Untergasser, Eberhard Gunsilius,  and Wolfgang Hilbe
20109-20123
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Prostate stromal cell proteomics analysis discriminates normal from tumour reactive stromal phenotypes

Prostate stromal cell proteomics analysis discriminates normal from tumour reactive stromal phenotypes

https://doi.org/10.18632/oncotarget.7716

Jason P. Webber, Lisa K. Spary, Malcolm D. Mason, Zsuzsanna Tabi, Ian A. Brewis,  and Aled Clayton
20124-20139
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Survival kinase genes present prognostic significance in glioblastoma

Survival kinase genes present prognostic significance in glioblastoma

https://doi.org/10.18632/oncotarget.7917

Robin T. Varghese, Yanping Liang, Ting Guan, Christopher T. Franck, Deborah F. Kelly,  and Zhi Sheng
20140-20151
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Insulin receptor substrate 1 is a substrate of the Pim protein kinases

Insulin receptor substrate 1 is a substrate of the Pim protein kinases

https://doi.org/10.18632/oncotarget.7918

Jin H. Song, Sathish K. R. Padi, Libia A. Luevano, Mark D. Minden, Daniel J. DeAngelo, Gary Hardiman, Lauren E. Ball, Noel A. Warfel,  and Andrew S. Kraft
20152-20165
Abstract  |  PDF  |  HTML  |  Order a Reprint

Folic-acid metabolism and DNA-repair phenotypes differ between neuroendocrine lung tumors and associate with aggressive subtypes, therapy resistance and outcome

Folic-acid metabolism and DNA-repair phenotypes differ between neuroendocrine lung tumors and associate with aggressive subtypes, therapy resistance and outcome

https://doi.org/10.18632/oncotarget.7737

Robert Fred Henry Walter, Fabian Dominik Mairinger, Robert Werner, Claudia Vollbrecht, Thomas Hager, Kurt Werner Schmid, Jeremias Wohlschlaeger,  and Daniel Christian Christoph
20166-20179
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Suppression of miR-204 enables oral squamous cell carcinomas to promote cancer stemness, EMT traits, and lymph node metastasis

Suppression of miR-204 enables oral squamous cell carcinomas to promote cancer stemness, EMT traits, and lymph node metastasis

https://doi.org/10.18632/oncotarget.7745

Cheng-Chia Yu, Pei-Ni Chen, Chih-Yu Peng, Chuan-Hang Yu,  and Ming- Yung Chou
20180-20192
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Bufalin suppresses hepatocellular carcinoma invasion and metastasis by targeting HIF-1α via the PI3K/AKT/mTOR pathway

Bufalin suppresses hepatocellular carcinoma invasion and metastasis by targeting HIF-1α via the PI3K/AKT/mTOR pathway

https://doi.org/10.18632/oncotarget.7935

Haiyong Wang, Chenyue Zhang, Litao Xu, Kun Zang, Zhouyu Ning, Feng Jiang, Huiying Chi, Xiaoyan Zhu,  and Zhiqiang Meng
20193-20208
Abstract  |  PDF  |  HTML  |  Order a Reprint

MicroRNA-92b represses invasion-metastasis cascade of esophageal squamous cell carcinoma

MicroRNA-92b represses invasion-metastasis cascade of esophageal squamous cell carcinoma

https://doi.org/10.18632/oncotarget.7747

Gang Ma, Chao Jing, Lin Li, Furong Huang, Fang Ding, Baona Wang, Dongmei Lin, Aiping Luo,  and Zhihua Liu
20209-20222
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Adipocytes WNT5a mediated dedifferentiation: a possible target in pancreatic cancer microenvironment

Adipocytes WNT5a mediated dedifferentiation: a possible target in pancreatic cancer microenvironment

https://doi.org/10.18632/oncotarget.7936

Elena Zoico, Elena Darra, Vanni Rizzatti, Simona Budui, Guido Franceschetti, Gloria Mazzali, Andrea P. Rossi, Francesco Fantin, Marta Menegazzi, Saverio Cinti,  and Mauro Zamboni
20223-20235
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Protein arginine methyltransferase 1 may be involved in pregnane x receptor-activated overexpression of multidrug resistance 1 gene during acquired multidrug resistant

Protein arginine methyltransferase 1 may be involved in pregnane x receptor-activated overexpression of multidrug resistance 1 gene during acquired multidrug resistant

https://doi.org/10.18632/oncotarget.7752

Tingting Li, Ah-Ng Tony Kong, Zhiqiang Ma, Haiyan Liu, Pinghua Liu, Yu Xiao, Xuehua Jiang,  and Ling Wang
20236-20248
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Icmt inhibition exerts anti-angiogenic and anti-hyperpermeability activities impeding malignant pleural effusion

Icmt inhibition exerts anti-angiogenic and anti-hyperpermeability activities impeding malignant pleural effusion

https://doi.org/10.18632/oncotarget.7912

Sophia Magkouta, Apostolos Pappas, Charalampos Moschos, Maria-Eleni Vazakidou, Katherina Psarra,  and Ioannis Kalomenidis
20249-20259
Abstract  |  PDF  |  HTML  |  Order a Reprint

Reactivation of epigenetically silenced miR-124 reverses the epithelial-to-mesenchymal transition and inhibits invasion in endometrial cancer cells via the direct repression of IQGAP1 expression

Reactivation of epigenetically silenced miR-124 reverses the epithelial-to-mesenchymal transition and inhibits invasion in endometrial cancer cells via the direct repression of IQGAP1 expression

https://doi.org/10.18632/oncotarget.7754

Peixin Dong, Kei Ihira, Ying Xiong, Hidemichi Watari, Sharon J.B. Hanley, Takahiro Yamada, Masayoshi Hosaka, Masataka Kudo, Junming Yue,  and Noriaki Sakuragi
20260-20270
Abstract  |  PDF  |  HTML  |  Order a Reprint

Prevention of irradiation-induced salivary hypofunction by rapamycin in swine parotid glands

Prevention of irradiation-induced salivary hypofunction by rapamycin in swine parotid glands

https://doi.org/10.18632/oncotarget.7941

Zhao Zhu, Baoxing Pang, Ramiro Iglesias-Bartolome, Xiaoshan Wu, Lei Hu, Chunmei Zhang, Jinsong Wang, J. Silvio Gutkind,  and Songlin Wang
20271-20281
Abstract  |  PDF  |  HTML  |  Order a Reprint

Repeated observation of immune gene sets enrichment in women with non-small cell lung cancer

Repeated observation of immune gene sets enrichment in women with non-small cell lung cancer

https://doi.org/10.18632/oncotarget.7943

Jhajaira M. Araujo, Alexandra Prado, Nadezhda K. Cardenas, Mayer Zaharia, Richard Dyer, Franco Doimi, Leny Bravo, Luis Pinillos, Zaida Morante, Alfredo Aguilar, Luis A. Mas, Henry L. Gomez, Carlos S. Vallejos, Christian Rolfo,  and Joseph A. Pinto
20282-20292
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

The effects of curcumin (diferuloylmethane) on body composition of patients with advanced pancreatic cancer

The effects of curcumin (diferuloylmethane) on body composition of patients with advanced pancreatic cancer

https://doi.org/10.18632/oncotarget.7773

Henrique A. Parsons, Vickie E. Baracos, David S. Hong, James Abbruzzese, Eduardo Bruera,  and Razelle Kurzrock
20293-20304
Abstract  |  PDF  |  HTML  |  Order a Reprint

ZCWPW1 is associated with late-onset Alzheimer's disease in Han Chinese: a replication study and meta-analyses

ZCWPW1 is associated with late-onset Alzheimer's disease in Han Chinese: a replication study and meta-analyses

https://doi.org/10.18632/oncotarget.7945

Yu Gao, Meng-Shan Tan, Hui-Fu Wang, Wei Zhang, Zi-Xuan Wang, Teng Jiang, Jin-Tai Yu,  and Lan Tan
20305-20311
Abstract  |  PDF  |  HTML  |  Order a Reprint

Exogenous hepatitis B virus envelope proteins induce endoplasmic reticulum stress: involvement of cannabinoid axis in liver cancer cells

Exogenous hepatitis B virus envelope proteins induce endoplasmic reticulum stress: involvement of cannabinoid axis in liver cancer cells

https://doi.org/10.18632/oncotarget.7950

Roberta Montalbano, Birgit Honrath, Thaddeus Till Wissniowski, Moritz Elxnat, Silvia Roth, Matthias Ocker, Karl Quint, Yuri Churin, Martin Roederfeld, Dirk Schroeder, Dieter Glebe, Elke Roeb,  and Pietro Di Fazio
20312-20323
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

miR-155 regulates the proliferation and invasion of clear cell renal cell carcinoma cells by targeting E2F2

miR-155 regulates the proliferation and invasion of clear cell renal cell carcinoma cells by targeting E2F2

https://doi.org/10.18632/oncotarget.7951

Yu Gao, Xin Ma, Yuanxin Yao, Hongzhao Li, Yang Fan, Yu Zhang, Chaofei Zhao, Lei Wang, Minghui Ma, Zhengwei Lei,  and Xu Zhang
20324-20337
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Everolimus exhibits anti-tumorigenic activity in obesity-induced ovarian cancer

Everolimus exhibits anti-tumorigenic activity in obesity-induced ovarian cancer

https://doi.org/10.18632/oncotarget.7934

Hui Guo, Yan Zhong, Amanda L. Jackson, Leslie H. Clark, Josh Kilgore, Lu Zhang, Jianjun Han, Xiugui Sheng, Timothy P. Gilliam, Paola A. Gehrig, Chunxiao Zhou,  and Victoria L. Bae-Jump
20338-20356
Abstract  |  PDF  |  HTML  |  Order a Reprint

The association of six polymorphisms of five genes involved in three steps of nucleotide excision repair pathways with hepatocellular cancer risk

The association of six polymorphisms of five genes involved in three steps of nucleotide excision repair pathways with hepatocellular cancer risk

https://doi.org/10.18632/oncotarget.7952

Bengang Wang, Qian Xu, Huai-wei Yang, Li-ping Sun,  and Yuan Yuan
20357-20367
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Antitumor effects of calgranulin B internalized in human colon cancer cells

Antitumor effects of calgranulin B internalized in human colon cancer cells

https://doi.org/10.18632/oncotarget.7783

Kun Kim, Kyung-Hee Kim, Kangsan Roh, Byong Chul Yoo, Ja-Lok Ku, Young-Kyoung Shin, Jae Youl Cho, Minjae Kim, Myung-Hee Kwon, Sung Ho Goh, Hee Jin Chang,  and Jae Hwan Oh
20368-20380
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

MiR-148a functions to suppress metastasis and serves as a prognostic indicator in triple-negative breast cancer

MiR-148a functions to suppress metastasis and serves as a prognostic indicator in triple-negative breast cancer

https://doi.org/10.18632/oncotarget.7953

Xin Xu, Yun Zhang, Jeff Jasper, Erik Lykken, Peter B. Alexander, Geoffrey J. Markowitz, Donald P. McDonnell, Qi-Jing Li,  and Xiao-Fan Wang
20381-20394
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

CWP232228 targets liver cancer stem cells through Wnt/β‑catenin signaling: a novel therapeutic approach for liver cancer treatment

CWP232228 targets liver cancer stem cells through Wnt/β‑catenin signaling: a novel therapeutic approach for liver cancer treatment

https://doi.org/10.18632/oncotarget.7954

Ji‑Young Kim, Hwa‑Yong Lee, Kwan‑Kyu Park, Yang‑Kyu Choi, Jeong‑Seok Nam,  and In‑Sun Hong
20395-20409
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Renal cell carcinoma alters endothelial receptor expression responsible for leukocyte adhesion

Renal cell carcinoma alters endothelial receptor expression responsible for leukocyte adhesion

https://doi.org/10.18632/oncotarget.7804

Eva Juengel, Geraldine Krueger, Jochen Rutz, Karen Nelson, Isabella Werner, Borna Relja, Barbara Seliger, Beate Fisslthaler, Ingrid Fleming, Igor Tsaur, Axel Haferkamp,  and Roman A. Blaheta
20410-20424
Abstract  |  PDF  |  HTML  |  Order a Reprint

Acetylation and deacetylation of Cdc25A constitutes a novel mechanism for modulating Cdc25A functions with implications for cancer

Acetylation and deacetylation of Cdc25A constitutes a novel mechanism for modulating Cdc25A functions with implications for cancer

https://doi.org/10.18632/oncotarget.7966

Enerlyn M. Lozada, Zdenek Andrysik, Moying Yin, Nicholas Redilla, Kathryn Rice,  and Peter J. Stambrook
20425-20439
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Glutamate dependent NMDA receptor 2D is a novel angiogenic tumour endothelial marker in colorectal cancer

Glutamate dependent NMDA receptor 2D is a novel angiogenic tumour endothelial marker in colorectal cancer

https://doi.org/10.18632/oncotarget.7812

Henry J.M. Ferguson, Joseph W. Wragg, Stephen Ward, Victoria L. Heath, Tariq Ismail,  and Roy Bicknell
20440-20454
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

The antinociceptive effects of ferulic acid on neuropathic pain: involvement of descending monoaminergic system and opioid receptors

The antinociceptive effects of ferulic acid on neuropathic pain: involvement of descending monoaminergic system and opioid receptors

https://doi.org/10.18632/oncotarget.7973

Ying Xu, Dan Lin, Xuefeng Yu, Xupei Xie, Liqun Wang, Lejing Lian, Ning Fei, Jie Chen, Naping Zhu, Gang Wang, Xianfeng Huang,  and Jianchun Pan
20455-20468
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Overexpression of pig selenoprotein S blocks OTA-induced promotion of PCV2 replication by inhibiting oxidative stress and p38 phosphorylation in PK15 cells

Overexpression of pig selenoprotein S blocks OTA-induced promotion of PCV2 replication by inhibiting oxidative stress and p38 phosphorylation in PK15 cells

https://doi.org/10.18632/oncotarget.7814

Fang Gan, Zhihua Hu, Yu Huang, Hongxia Xue, Da Huang, Gang Qian, Junfa Hu, Xingxiang Chen, Tian Wang,  and Kehe Huang
20469-20485
Abstract  |  PDF  |  HTML  |  Order a Reprint

Metabolomics profiling in plasma samples from glioma patients correlates with tumor phenotypes

Metabolomics profiling in plasma samples from glioma patients correlates with tumor phenotypes

https://doi.org/10.18632/oncotarget.7974

Hua Zhao, Amy B. Heimberger, Zhimin Lu, Xifeng Wu, Tiffany R. Hodges, Renduo Song,  and Jie Shen
20486-20495
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Nomograms to estimate long-term overall survival and breast cancer-specific survival of patients with luminal breast cancer

Nomograms to estimate long-term overall survival and breast cancer-specific survival of patients with luminal breast cancer

https://doi.org/10.18632/oncotarget.7975

Wei Sun, Yi-Zhou Jiang, Yi-Rong Liu, Ding Ma,  and Zhi-Ming Shao
20496-20506
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

The effect of HMGB1 on the clinicopathological and prognostic features of non-small cell lung cancer

The effect of HMGB1 on the clinicopathological and prognostic features of non-small cell lung cancer

https://doi.org/10.18632/oncotarget.7050

Anlin Feng, Zhenbo Tu,  and Bingjiao Yin
20507-20519
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Immunoglobulin gene rearrangements in Chinese and Italian patients with chronic lymphocytic leukemia

Immunoglobulin gene rearrangements in Chinese and Italian patients with chronic lymphocytic leukemia

https://doi.org/10.18632/oncotarget.7819

Marilisa Marinelli, Caterina Ilari, Yi Xia, Ilaria Del Giudice, Luciana Cafforio, Irene Della Starza, Sara Raponi, Paola Mariglia, Silvia Bonina, Zhen Yu, Wenjuan Yang, Lugui Qiu, Thomas Chan, Alfonso Piciocchi, Yok-Lam Kwong, Eric Tse, Jianyong Li, Anna Guarini, Wei Xu,  and Robin Foà
20520-20531
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Multitargeting activity of miR-24 inhibits long-term melatonin anticancer effects

Multitargeting activity of miR-24 inhibits long-term melatonin anticancer effects

https://doi.org/10.18632/oncotarget.7978

Federica Mori, Maria Ferraiuolo, Raffaela Santoro, Andrea Sacconi, Frauke Goeman, Matteo Pallocca, Claudio Pulito, Etleva Korita, Maurizio Fanciulli, Paola Muti, Giovanni Blandino,  and Sabrina Strano
20532-20548
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Lnc-SGK1 induced by Helicobacter pylori infection and highsalt diet promote Th2 and Th17 differentiation in human gastric cancer by SGK1/Jun B signaling

Lnc-SGK1 induced by Helicobacter pylori infection and highsalt diet promote Th2 and Th17 differentiation in human gastric cancer by SGK1/Jun B signaling

https://doi.org/10.18632/oncotarget.7823

Yongliang Yao, Qingbo Jiang, Lixing Jiang, Jianhong Wu, Qinghui Zhang, Jianjun Wang, Huang Feng,  and Panpan Zang
20549-20560
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

RalA, a GTPase targeted by miR‑181a, promotes transformation and progression by activating the Ras‑related signaling pathway in chronic myelogenous leukemia

RalA, a GTPase targeted by miR‑181a, promotes transformation and progression by activating the Ras‑related signaling pathway in chronic myelogenous leukemia

https://doi.org/10.18632/oncotarget.7987

Chunming Gu, Maoxiao Feng, Zhao Yin, Xiaochuang Luo, Juhua Yang, Yumin Li, Tianfu Li, Ruirui Wang,  and Jia Fei
20561-20573
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

The clock gene PER1 suppresses expression of tumor-related genes in human oral squamous cell carcinoma

The clock gene PER1 suppresses expression of tumor-related genes in human oral squamous cell carcinoma

https://doi.org/10.18632/oncotarget.7827

Han-Xue Li, Xiao-Juan Fu, Kai Yang, Dan Chen, Hong Tang,  and Qin Zhao
20574-20583
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Long non-coding RNAs as prognostic markers in human breast cancer

Long non-coding RNAs as prognostic markers in human breast cancer

https://doi.org/10.18632/oncotarget.7828

Hairong Liu, Juan Li, Pratirodh Koirala, Xianfeng Ding, Binghai Chen, Yiheng Wang, Zheng Wang, Chuanxin Wang, Xu Zhang,  and Yin-Yuan Mo
20584-20596
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

MEK1 signaling promotes self-renewal and tumorigenicity of liver cancer stem cells via maintaining SIRT1 protein stabilization

MEK1 signaling promotes self-renewal and tumorigenicity of liver cancer stem cells via maintaining SIRT1 protein stabilization

https://doi.org/10.18632/oncotarget.7972

Jiamin Cheng, Chungang Liu, Limei Liu, Xuejiao Chen, Juanjuan Shan, Junjie Shen, Wei Zhu,  and Cheng Qian
20597-20611
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Pre-treatment evaluation of 5-fluorouracil degradation rate: association of poor and ultra-rapid metabolism with severe toxicity in a colorectal cancer patients cohort

Pre-treatment evaluation of 5-fluorouracil degradation rate: association of poor and ultra-rapid metabolism with severe toxicity in a colorectal cancer patients cohort

https://doi.org/10.18632/oncotarget.7991

Federica Mazzuca, Marina Borro, Andrea Botticelli, Eva Mazzotti, Luca Marchetti, Giovanna Gentile, Marco La Torre, Luana Lionetto, Maurizio Simmaco,  and Paolo Marchetti
20612-20620
Abstract  |  PDF  |  HTML  |  Order a Reprint

Loss of SOCS3 in myeloid cells prolongs survival in a syngeneic model of glioma

Loss of SOCS3 in myeloid cells prolongs survival in a syngeneic model of glioma

https://doi.org/10.18632/oncotarget.7992

Braden C. McFarland, Margaret P. Marks, Amber L. Rowse, Samuel C. Fehling, Magda Gerigk, Hongwei Qin,  and Etty N. Benveniste
20621-20635
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Long non-coding RNA containing ultraconserved genomic region 8 promotes bladder cancer tumorigenesis

Long non-coding RNA containing ultraconserved genomic region 8 promotes bladder cancer tumorigenesis

https://doi.org/10.18632/oncotarget.7833

Michele Olivieri, Matteo Ferro, Sara Terreri, Montano Durso, Alessandra Romanelli, Concetta Avitabile, Ottavio De Cobelli, Anna Messere, Dario Bruzzese, Ivan Vannini, Luciana Marinelli, Ettore Novellino, Wei Zhang, Mariarosaria Incoronato, Gennaro Ilardi, Stefania Staibano, Laura Marra, Renato Franco, Sisto Perdonà, Daniela Terracciano, Bogdan Czerniak, Giovanna L. Liguori, Vincenza Colonna, Muller Fabbri, Ferdinando Febbraio, George A. Calin,  and Amelia Cimmino
20636-20654
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Dephosphorylation and mitochondrial translocation of cofilin sensitizes human leukemia cells to cerulenin-induced apoptosis via the ROCK1/Akt/JNK signaling pathway

Dephosphorylation and mitochondrial translocation of cofilin sensitizes human leukemia cells to cerulenin-induced apoptosis via the ROCK1/Akt/JNK signaling pathway

https://doi.org/10.18632/oncotarget.7994

Yanhao Zhang, Ruoqiu Fu, Yanxia Liu, Jing Li, Hongwei Zhang, Xiaoye Hu, Yibiao Chen, Xin Liu, Yunong Li, Ping Li, Ehu Liu,  and Ning Gao
20655-20668
Abstract  |  PDF  |  HTML  |  Order a Reprint

Signal transducer and activator of transcription 3 (STAT3) inhibitor, S3I-201, acts as a potent and non-selective alkylating agent

Signal transducer and activator of transcription 3 (STAT3) inhibitor, S3I-201, acts as a potent and non-selective alkylating agent

https://doi.org/10.18632/oncotarget.7838

Daniel P. Ball, Andrew M. Lewis, Declan Williams, Diana Resetca, Derek J. Wilson,  and Patrick T. Gunning
20669-20679
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

The efficacy and toxicity of individualized intensity‑modulated radiotherapy based on the tumor extension patterns of nasopharyngeal carcinoma

The efficacy and toxicity of individualized intensity‑modulated radiotherapy based on the tumor extension patterns of nasopharyngeal carcinoma

https://doi.org/10.18632/oncotarget.8004

Li Lin, Ji‑Jin Yao, Guan‑Qun Zhou, Rui Guo, Fan Zhang, Yuan Zhang, Lin Xu, Lu‑Lu Zhang, Ai‑Hua Lin, Jun Ma,  and Ying Sun
20680-20690
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Repeated PM2.5 exposure inhibits BEAS-2B cell P53 expression through ROS-Akt-DNMT3B pathway-mediated promoter hypermethylation

Repeated PM2.5 exposure inhibits BEAS-2B cell P53 expression through ROS-Akt-DNMT3B pathway-mediated promoter hypermethylation

https://doi.org/10.18632/oncotarget.7842

Wei Zhou, Dongdong Tian, Jun He, Yimei Wang, Lijun Zhang, Lan Cui, Li Jia, Li Zhang, Lizhong Li, Yulei Shu, Shouzhong Yu, Jun Zhao, Xiaoyan Yuan,  and Shuangqing Peng
20691-20703
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

The long non-coding RNA EPB41L4A-AS2 inhibits tumor proliferation and is associated with favorable prognoses in breast cancer and other solid tumors

The long non-coding RNA EPB41L4A-AS2 inhibits tumor proliferation and is associated with favorable prognoses in breast cancer and other solid tumors

https://doi.org/10.18632/oncotarget.8007

Shouping Xu, Peiyuan Wang, Zilong You, Hongxue Meng, Guannan Mu, Xianan Bai, Guangwen Zhang, Jinfeng Zhang,  and Da Pang
20704-20717
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Inhibition of estrogen biosynthesis enhances lymphoma growth in mice

Inhibition of estrogen biosynthesis enhances lymphoma growth in mice

https://doi.org/10.18632/oncotarget.7843

Gergely Talaber, Konstantin Yakimchuk, Jiyu Guan, Jose Inzunza,  and Sam Okret
20718-20727
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

MicroRNA-137 inhibits tumor growth and sensitizes chemosensitivity to paclitaxel and cisplatin in lung cancer

MicroRNA-137 inhibits tumor growth and sensitizes chemosensitivity to paclitaxel and cisplatin in lung cancer

https://doi.org/10.18632/oncotarget.8011

Hua Shen, Lin Wang, Xin Ge, Cheng-Fei Jiang, Zhu-Mei Shi, Dong-Mei Li, Wei-Tao Liu, Xiaobo Yu,  and Yong-Qian Shu
20728-20742
Abstract  |  PDF  |  HTML  |  Order a Reprint

The preclinical study of predicting radiosensitivity in human nasopharyngeal carcinoma xenografts by 18F-ML-10 animal- PET/CT imaging

The preclinical study of predicting radiosensitivity in human nasopharyngeal carcinoma xenografts by 18F-ML-10 animal- PET/CT imaging

https://doi.org/10.18632/oncotarget.7868

Xiao Bao, Zhongyi Yang, Siyang Wang, Yujia Zheng, Mingwei Wang, Bingxin Gu, Jianping Zhang, Yongping Zhang,  and Yingjian Zhang
20743-20752
Abstract  |  PDF  |  HTML  |  Order a Reprint

Zoledronic acid-encapsulating self-assembling nanoparticles and doxorubicin: a combinatorial approach to overcome simultaneously chemoresistance and immunoresistance in breast tumors

Zoledronic acid-encapsulating self-assembling nanoparticles and doxorubicin: a combinatorial approach to overcome simultaneously chemoresistance and immunoresistance in breast tumors

https://doi.org/10.18632/oncotarget.8012

Joanna Kopecka, Stefania Porto, Sara Lusa, Elena Gazzano, Giuseppina Salzano, Martha Leonor Pinzòn-Daza, Antonio Giordano, Vincenzo Desiderio, Dario Ghigo, Giuseppe De Rosa, Michele Caraglia,  and Chiara Riganti
20753-20772
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Whole transcriptome profiling of patient-derived xenograft models as a tool to identify both tumor and stromal specific biomarkers

Whole transcriptome profiling of patient-derived xenograft models as a tool to identify both tumor and stromal specific biomarkers

https://doi.org/10.18632/oncotarget.8014

James R. Bradford, Mark Wappett, Garry Beran, Armelle Logie, Oona Delpuech, Henry Brown, Joanna Boros, Nicola J. Camp, Robert McEwen, Anne Marie Mazzola, Celina D’Cruz,  and Simon T. Barry
20773-20787
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Radiation therapy generates platelet-activating factor agonists

Radiation therapy generates platelet-activating factor agonists

https://doi.org/10.18632/oncotarget.7878

Ravi P. Sahu, Kathleen A. Harrison, Jonathan Weyerbacher, Robert C. Murphy, Raymond L. Konger, Joy Elizabeth Garrett, Helen Jan Chin-Sinex, Michael Edward Johnston II, Joseph R. Dynlacht, Marc Mendonca, Kevin McMullen, Gengxin Li, Dan F. Spandau,  and Jeffrey B. Travers
20788-20800
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

EphA8 is a prognostic marker for epithelial ovarian cancer

EphA8 is a prognostic marker for epithelial ovarian cancer

https://doi.org/10.18632/oncotarget.8018

Xiaoqin Liu, Yunzhao Xu, Qin Jin, Wei Wang, Shu Zhang, Xudong Wang, Yuquan Zhang, Xujuan Xu,  and Jianfei Huang
20801-20809
Abstract  |  PDF  |  HTML  |  Order a Reprint

Quantification of mutant alleles in circulating tumor DNA can predict survival in lung cancer

Quantification of mutant alleles in circulating tumor DNA can predict survival in lung cancer

https://doi.org/10.18632/oncotarget.8021

Xue Yang, Minglei Zhuo, Xin Ye, Hua Bai, Zhijie Wang, Yun Sun, Jun Zhao, Tongtong An, Jianchun Duan, Meina Wu,  and Jie Wang
20810-20824
Abstract  |  PDF  |  HTML  |  Order a Reprint

Reciprocal positive selection for weakness - preventing olaparib resistance by inhibiting BRCA2

Reciprocal positive selection for weakness - preventing olaparib resistance by inhibiting BRCA2

https://doi.org/10.18632/oncotarget.7883

Mateusz Rytelewski, Saman Maleki Vareki, Lingegowda S. Mangala, Larissa Romanow, Dahai Jiang, Sunila Pradeep, Christian Rodriguez-Aguayo, Gabriel Lopez-Berestein, Rene Figueredo, Peter J. Ferguson, Mark Vincent, Anil K. Sood,  and James D. Koropatnick
20825-20839
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Positive feedback regulation between IL10 and EGFR promotes lung cancer formation

Positive feedback regulation between IL10 and EGFR promotes lung cancer formation

https://doi.org/10.18632/oncotarget.7894

Tsung-I Hsu, Yi-Chang Wang, Chia-Yang Hung, Chun-Hui Yu, Wu-Chou Su, Wen-Chang Chang,  and Jan-Jong Hung
20840-20854
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

The Bif-1-Dynamin 2 membrane fission machinery regulates Atg9-containing vesicle generation at the Rab11-positive reservoirs

The Bif-1-Dynamin 2 membrane fission machinery regulates Atg9-containing vesicle generation at the Rab11-positive reservoirs

https://doi.org/10.18632/oncotarget.8028

Yoshinori Takahashi, Nikolaos Tsotakos, Ying Liu, Megan M. Young, Jacob Serfass, Zhenyuan Tang, Thomas Abraham,  and Hong-Gang Wang
20855-20868
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Geminin overexpression-dependent recruitment and crosstalk with mesenchymal stem cells enhance aggressiveness in triple negative breast cancers

Geminin overexpression-dependent recruitment and crosstalk with mesenchymal stem cells enhance aggressiveness in triple negative breast cancers

https://doi.org/10.18632/oncotarget.8029

Suryatheja Ananthula, Abhilasha Sinha, Mohamed El Gassim, Simran Batth, Gailen D. Marshall Jr., Lauren H. Gardner, Yoshiko Shimizu,  and Wael M. ElShamy
20869-20889
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

The synergic antitumor effects of paclitaxel and temozolomide co-loaded in mPEG-PLGA nanoparticles on glioblastoma cells

The synergic antitumor effects of paclitaxel and temozolomide co-loaded in mPEG-PLGA nanoparticles on glioblastoma cells

https://doi.org/10.18632/oncotarget.7896

Yuanyuan Xu, Ming Shen, Yiming Li, Ying Sun, Yanwei Teng, Yi Wang,  and Yourong Duan
20890-20901
Abstract  |  PDF  |  HTML  |  Order a Reprint

Protective role of p53 in skin cancer: Carcinogenesis studies in mice lacking epidermal p53

Protective role of p53 in skin cancer: Carcinogenesis studies in mice lacking epidermal p53

https://doi.org/10.18632/oncotarget.7897

Angustias Page, Manuel Navarro, Cristian Suarez-Cabrera, Josefa P. Alameda, M. Llanos Casanova, Jesús M. Paramio, Ana Bravo,  and Angel Ramirez
20902-20918
Abstract  |  PDF  |  HTML  |  Order a Reprint

Protein kinase C beta II suppresses colorectal cancer by regulating IGF-1 mediated cell survival

Protein kinase C beta II suppresses colorectal cancer by regulating IGF-1 mediated cell survival

https://doi.org/10.18632/oncotarget.8062

Catríona M. Dowling, James Phelan, Julia A. Callender, Mary Clare Cathcart, Brian Mehigan, Paul McCormick, Tara Dalton, John C. Coffey, Alexandra C. Newton, Jacintha O’Sullivan,  and Patrick A. Kiely
20919-20933
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Activation of mesenchymal stem cells by macrophages promotes tumor progression through immune suppressive effects

Activation of mesenchymal stem cells by macrophages promotes tumor progression through immune suppressive effects

https://doi.org/10.18632/oncotarget.8064

Xiao-hua Jia, Guo-wei Feng, Zhong-liang Wang, Yang Du, Chen Shen, Hui Hui, Dong Peng, Zong-jin Li, De-ling Kong,  and Jie Tian
20934-20944
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Tenascin-C serum levels and its prognostic power in non-small cell lung cancer

Tenascin-C serum levels and its prognostic power in non-small cell lung cancer

https://doi.org/10.18632/oncotarget.7976

Florian Gebauer, Suyin Gelis, Hilke Zander, Karl-Frederick Meyer, Gerrit Wolters-Eisfeld, Jakob R. Izbicki, Maximilian Bockhorn,  and Michael Tachezy
20945-20952
Abstract  |  PDF  |  HTML  |  Order a Reprint

Inhibition of miR301 enhances Akt-mediated cell proliferation by accumulation of PTEN in nucleus and its effects on cell-cycle regulatory proteins

Inhibition of miR301 enhances Akt-mediated cell proliferation by accumulation of PTEN in nucleus and its effects on cell-cycle regulatory proteins

https://doi.org/10.18632/oncotarget.7996

Mayur V. Jain, Ahmad Shareef, Wirginia Likus, Artur Cieślar-Pobuda, Saeid Ghavami,  and Marek J. Łos
20953-20965
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

ERα propelled aberrant global DNA hypermethylation by activating the DNMT1 gene to enhance anticancer drug resistance in human breast cancer cells

ERα propelled aberrant global DNA hypermethylation by activating the DNMT1 gene to enhance anticancer drug resistance in human breast cancer cells

https://doi.org/10.18632/oncotarget.8038

Xinxin Si, Yue Liu, Jinghuan Lv, Haijian Ding, Xin A. Zhang, Lipei Shao, Nan Yang, He Cheng, Luan Sun, Dongliang Zhu, Yin Yang, Andi Li, Xiao Han,  and Yujie Sun
20966-20980
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

MAPK15 upregulation promotes cell proliferation and prevents DNA damage in male germ cell tumors

MAPK15 upregulation promotes cell proliferation and prevents DNA damage in male germ cell tumors

https://doi.org/10.18632/oncotarget.8044

Matteo Rossi, David Colecchia, Gennaro Ilardi, Mario Acunzo, Giovanni Nigita, Federica Sasdelli, Angela Celetti, Angela Strambi, Stefania Staibano, Carlo Maria Croce,  and Mario Chiariello
20981-20998
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Transcription factor RUNX2 up-regulates chemokine receptor CXCR4 to promote invasive and metastatic potentials of human gastric cancer

Transcription factor RUNX2 up-regulates chemokine receptor CXCR4 to promote invasive and metastatic potentials of human gastric cancer

https://doi.org/10.18632/oncotarget.8236

Zheng-Jun Guo, Lang Yang, Feng Qian, Yan-Xia Wang, Xi Yu, Cheng-Dong Ji, Wei Cui, Dong-Fang Xiang, Xia Zhang, Peng Zhang, Ji Ming Wang, You-Hong Cui,  and Xiu-Wu Bian
20999-21012
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Clinical Research Papers

The role of adjuvant chemotherapy in nasopharyngeal carcinoma with bulky neck lymph nodes in the era of IMRT

The role of adjuvant chemotherapy in nasopharyngeal carcinoma with bulky neck lymph nodes in the era of IMRT

https://doi.org/10.18632/oncotarget.7849

Tingting Xu, Chunying Shen, Xiaomin Ou, Xiayun He, Hongmei Ying,  and Chaosu Hu
21013-21022
Abstract  |  PDF  |  HTML  |  Order a Reprint

Development of a new outcome prediction model for Chinese patients with penile squamous cell carcinoma based on preoperative serum C-reactive protein, body mass index, and standard pathological risk factors: the TNCB score group system

Development of a new outcome prediction model for Chinese patients with penile squamous cell carcinoma based on preoperative serum C-reactive protein, body mass index, and standard pathological risk factors: the TNCB score group system

https://doi.org/10.18632/oncotarget.8037

Zai-Shang Li, Peng Chen, Kai Yao, Bin Wang, Jing Li, Qi-Wu Mi, Xiao-Feng Chen, Qi Zhao, Yong-Hong Li, Jie-Ping Chen, Chuang-Zhong Deng, Yun-Lin Ye, Ming-Zhu Zhong, Zhuo-Wei Liu, Zi-Ke Qin, Xiang-Tian Lin, Wei-Cong Liang, Hui Han,  and Fang-Jian Zhou
21023-21033
Abstract  |  PDF  |  HTML  |  Order a Reprint

Longterm effects of palliative local treatment of incurable metastatic lesions in colorectal cancer patients

Longterm effects of palliative local treatment of incurable metastatic lesions in colorectal cancer patients

https://doi.org/10.18632/oncotarget.8090

Qiong Yang, Fangxin Liao, Yuanyuan Huang, Chang Jiang, Shousheng Liu, Wenzhuo He, Pengfei Kong, Bei Zhang,  and Liangping Xia
21034-21045
Abstract  |  PDF  |  HTML  |  Order a Reprint

Development and validation of a prognostic nomogram based on the log odds of positive lymph nodes (LODDS) for breast cancer

Development and validation of a prognostic nomogram based on the log odds of positive lymph nodes (LODDS) for breast cancer

https://doi.org/10.18632/oncotarget.8091

Jiahuai Wen, Feng Ye, Xiaofang He, Shuaijie Li, Xiaojia Huang, Xiangsheng Xiao,  and Xiaoming Xie
21046-21053
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Development and validation of a surgical-pathologic staging and scoring system for cervical cancer

Development and validation of a surgical-pathologic staging and scoring system for cervical cancer

https://doi.org/10.18632/oncotarget.8245

Shuang Li, Xiong Li, Yuan Zhang, Hang Zhou, Fangxu Tang, Yao Jia, Ting Hu, Haiying Sun, Ru Yang, Yile Chen, Xiaodong Cheng, Weiguo Lv, Li Wu, Jin Zhou, Shaoshuai Wang, Kecheng Huang, Lin Wang, Yuan Yao, Qifeng Yang, Xingsheng Yang, Qinghua Zhang, Xiaobing Han, Zhongqiu Lin, Hui Xing, Pengpeng Qu, Hongbing Cai, Xiaojie Song, Xiaoyu Tian, Jian Shen, Ling Xi, Kezhen Li, Dongrui Deng, Hui Wang, Changyu Wang, Mingfu Wu, Tao Zhu, Gang Chen, Qinglei Gao, Shixuan Wang, Junbo Hu, Beihua Kong, Xing Xie,  and Ding Ma
21054-21063
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint


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