Oncotarget

Vol 7, No 14

April 5, 2016

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Oncogenic AKT1(E17K) mutation induces mammary hyperplasia but prevents HER2-driven tumorigenesis. See Mancini et al.

Table of Contents

Editorial

KCNE2 and gastric cancer: bench to bedside

KCNE2 and gastric cancer: bench to bedside

https://doi.org/10.18632/oncotarget.7921

Geoffrey W. Abbott,  and Torsten K. Roepke
17286-17287
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BAI1: from cancer to neurological disease

BAI1: from cancer to neurological disease

https://doi.org/10.18632/oncotarget.8193

Dan Zhu,  and Erwin G. Van Meir
17288-17289
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Priority Research Papers

Ruxolitinib synergizes with DMF to kill via BIM+BAD-induced mitochondrial dysfunction and via reduced SOD2/TRX expression and ROS

Ruxolitinib synergizes with DMF to kill via BIM+BAD-induced mitochondrial dysfunction and via reduced SOD2/TRX expression and ROS

https://doi.org/10.18632/oncotarget.8039

Mehrad Tavallai, Laurence Booth, Jane L. Roberts, William P. McGuire, Andrew Poklepovic,  and Paul Dent
17290-17300
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Oncogenic AKT1(E17K) mutation induces mammary hyperplasia but prevents HER2-driven tumorigenesis

Oncogenic AKT1(E17K) mutation induces mammary hyperplasia but prevents HER2-driven tumorigenesis

https://doi.org/10.18632/oncotarget.8191

Maria L. Mancini, Evan C. Lien,  and Alex Toker
17301-17313
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Serum HER2 levels are increased in cats with mammary carcinomas and predict tissue HER2 status

Serum HER2 levels are increased in cats with mammary carcinomas and predict tissue HER2 status

https://doi.org/10.18632/oncotarget.7551

Maria Soares, Rita Ribeiro, Shabir Najmudin, Andreia Gameiro, Rita Rodrigues, Fátima Cardoso,  and Fernando Ferreira
17314-17326
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Research Papers: Gerotarget (Focus on Aging)

Age-related reduction of antibody response against the human endogenous retrovirus K envelope in women

Age-related reduction of antibody response against the human endogenous retrovirus K envelope in women

https://doi.org/10.18632/oncotarget.7307

Hyoung Jin Kim, Byung-In Moon, Jun Woo Lee, Seung Cheol Kim,  and Hong-Jin Kim
17327-17337
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Improved muscle function and quality after diet intervention with leucine-enriched whey and antioxidants in antioxidant deficient aged mice

Improved muscle function and quality after diet intervention with leucine-enriched whey and antioxidants in antioxidant deficient aged mice

https://doi.org/10.18632/oncotarget.7800

Miriam van Dijk, Francina J. Dijk, Annelies Bunschoten, Dorien A.M. van Dartel, Klaske van Norren, Stephane Walrand, Marion Jourdan, Sjors Verlaan,  and Yvette Luiking
17338-17355
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Tau accumulation impairs mitophagy via increasing mitochondrial membrane potential and reducing mitochondrial Parkin

Tau accumulation impairs mitophagy via increasing mitochondrial membrane potential and reducing mitochondrial Parkin

https://doi.org/10.18632/oncotarget.7861

Yu Hu, Xia-Chun Li, Zhi-hao Wang, Yu Luo, Xiangnan Zhang, Xiu-Ping Liu, Qiong Feng, Qun Wang, Zhenyu Yue, Zhong Chen, Keqiang Ye, Jian-Zhi Wang,  and Gong-Ping Liu
17356-17368
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Oral isoflavone supplementation on endometrial thickness: a meta-analysis of randomized placebo-controlled trials

Oral isoflavone supplementation on endometrial thickness: a meta-analysis of randomized placebo-controlled trials

https://doi.org/10.18632/oncotarget.7959

Jie Liu, Feixiang Yuan, Jian Gao, Boer Shan, Yulan Ren, Huaying Wang,  and Ying Gao
17369-17379
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The effect of resveratrol on beta amyloid-induced memory impairment involves inhibition of phosphodiesterase-4 related signaling

The effect of resveratrol on beta amyloid-induced memory impairment involves inhibition of phosphodiesterase-4 related signaling

https://doi.org/10.18632/oncotarget.8041

Gang Wang, Ling Chen, Xiaoyu Pan, Jiechun Chen, Liqun Wang, Weijie Wang, Ruochuan Cheng, Fan Wu, Xiaoqing Feng, Yingcong Yu, Han-Ting Zhang, James M. O’Donnell,  and Ying Xu
17380-17392
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C-phycocyanin protects against low fertility by inhibiting reactive oxygen species in aging mice

C-phycocyanin protects against low fertility by inhibiting reactive oxygen species in aging mice

https://doi.org/10.18632/oncotarget.8165

Yan-Jiao Li, Zhe Han, Lei Ge, Cheng-Jie Zhou, Yue-Fang Zhao, Dong-Hui Wang, Jing Ren, Xin-Xin Niu,  and Cheng-Guang Liang
17393-17409
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Genetic overlap between type 2 diabetes and major depressive disorder identified by bioinformatics analysis

Genetic overlap between type 2 diabetes and major depressive disorder identified by bioinformatics analysis

https://doi.org/10.18632/oncotarget.8202

Hong-Fang Ji, Qi-Shuai Zhuang,  and Liang Shen
17410-17414
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Up-regulation of serotonin receptor 2B mRNA and protein in the peri-infarcted area of aged rats and stroke patients

Up-regulation of serotonin receptor 2B mRNA and protein in the peri-infarcted area of aged rats and stroke patients

https://doi.org/10.18632/oncotarget.8277

Ana-Maria Buga, Ovidiu Ciobanu, George Mihai Bădescu, Catalin Bogdan, Ria Weston, Mark Slevin, Mario Di Napoli,  and Aurel Popa-Wagner
17415-17430
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Research Papers: Pathology

A disintegrin and metalloprotease 10 (ADAM10) is a central regulator of murine liver tissue homeostasis

A disintegrin and metalloprotease 10 (ADAM10) is a central regulator of murine liver tissue homeostasis

https://doi.org/10.18632/oncotarget.7836

Miryam Müller, Sebastian Wetzel, Julia Köhn-Gaone, Karel Chalupsky, Renate Lüllmann-Rauch, Roja Barikbin, Juri Bergmann, Birte Wöhner, Olga Zbodakova, Ivo Leuschner, Gregor Martin, Gisa Tiegs, Stefan Rose-John, Radislav Sedlacek, Janina E.E. Tirnitz-Parker, Paul Saftig,  and Dirk Schmidt-Arras
17431-17441
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Concordance of folate receptor-α expression between biopsy, primary tumor and metastasis in breast cancer and lung cancer patients

Concordance of folate receptor-α expression between biopsy, primary tumor and metastasis in breast cancer and lung cancer patients

https://doi.org/10.18632/oncotarget.7856

Leonora S.F. Boogerd, Martin C. Boonstra, Ann-Jean Beck, Ayoub Charehbili, Charlotte E.S. Hoogstins, Hendrica A.J.M. Prevoo, Sunil Singhal, Philip S. Low, Cornelis J.H. van de Velde,  and Alexander L. Vahrmeijer
17442-17454
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Distinct functions and regulation of epithelial progesterone receptor in the mouse cervix, vagina, and uterus

Distinct functions and regulation of epithelial progesterone receptor in the mouse cervix, vagina, and uterus

https://doi.org/10.18632/oncotarget.8159

Fabiola F. Mehta, Jieun Son, Sylvia C. Hewitt, Eunjung Jang, John P. Lydon, Kenneth S. Korach,  and Sang-Hyuk Chung
17455-17467
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Emodin via colonic irrigation modulates gut microbiota and reduces uremic toxins in rats with chronic kidney disease

Emodin via colonic irrigation modulates gut microbiota and reduces uremic toxins in rats with chronic kidney disease

https://doi.org/10.18632/oncotarget.8160

Yu-Qun Zeng, Zhenhua Dai, Fuhua Lu, Zhaoyu Lu, Xusheng Liu, Cha Chen, Pinghua Qu, Dingcheng Li, Zhengshuang Hua, Yanni Qu,  and Chuan Zou
17468-17478
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Mitochondrial reactive oxygen species-mediated NLRP3 inflammasome activation contributes to aldosterone-induced renal tubular cells injury

Mitochondrial reactive oxygen species-mediated NLRP3 inflammasome activation contributes to aldosterone-induced renal tubular cells injury

https://doi.org/10.18632/oncotarget.8243

Wei Ding, Honglei Guo, Chengyan Xu, Bin Wang, Minmin Zhang,  and Feng Ding
17479-17491
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Research Papers: Immunology

Porcine circovirus type 2 activates PI3K/Akt and p38 MAPK pathways to promote interleukin-10 production in macrophages via Cap interaction of gC1qR

Porcine circovirus type 2 activates PI3K/Akt and p38 MAPK pathways to promote interleukin-10 production in macrophages via Cap interaction of gC1qR

https://doi.org/10.18632/oncotarget.7362

Qian Du, Yong Huang, Tongtong Wang, Xiujuan Zhang, Yu Chen, Beibei Cui, Delong Li, Xiaomin Zhao, Wenlong Zhang, Lingling Chang,  and Dewen Tong
17492-17507
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Nickel chloride (NiCl2) induces endoplasmic reticulum (ER) stress by activating UPR pathways in the kidney of broiler chickens

Nickel chloride (NiCl2) induces endoplasmic reticulum (ER) stress by activating UPR pathways in the kidney of broiler chickens

https://doi.org/10.18632/oncotarget.7919

Hongrui Guo, Hengmin Cui, Xi Peng, Jing Fang, Zhicai Zuo, Junliang Deng, Xun Wang, Bangyuan Wu, Kejie Chen,  and Jie Deng
17508-17519
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MiR-128-2 inhibits common lymphoid progenitors from developing into progenitor B cells

MiR-128-2 inhibits common lymphoid progenitors from developing into progenitor B cells

https://doi.org/10.18632/oncotarget.8161

Yi Yang, Jie Xu, Huo Chen, Xia Fei, YuXu Tang, Yunqiu Yan, Huimin Zhang,  and Jinping Zhang
17520-17531
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FoxO1 regulates allergic asthmatic inflammation through regulating polarization of the macrophage inflammatory phenotype

FoxO1 regulates allergic asthmatic inflammation through regulating polarization of the macrophage inflammatory phenotype

https://doi.org/10.18632/oncotarget.8162

Sangwoon Chung, Tae Jin Lee, Brenda F. Reader, Ji Young Kim, Yong Gyu Lee, Gye Young Park, Manjula Karpurapu, Megan N. Ballinger, Feng Qian, Luiza Rusu, Hae Young Chung, Terry G. Unterman, Carlo M. Croce,  and John W. Christman
17532-17546
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Rainbow trout CK9, a CCL25-like ancient chemokine that attracts and regulates B cells and macrophages, the main antigen presenting cells in fish

Rainbow trout CK9, a CCL25-like ancient chemokine that attracts and regulates B cells and macrophages, the main antigen presenting cells in fish

https://doi.org/10.18632/oncotarget.8163

Carolina Aquilino, Aitor G. Granja, Rosario Castro, Tiehui Wang, Beatriz Abos, David Parra, Christopher J. Secombes,  and Carolina Tafalla
17547-17564
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

T cells conditioned with MDSC show an increased anti-tumor activity after adoptive T cell based immunotherapy

T cells conditioned with MDSC show an increased anti-tumor activity after adoptive T cell based immunotherapy

https://doi.org/10.18632/oncotarget.8197

Patrick L. Raber, Rosa A. Sierra, Paul T. Thevenot, Zhang Shuzhong, Dorota D. Wyczechowska, Takumi Kumai, Esteban Celis,  and Paulo C. Rodriguez
17565-17578
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Artificial antigen-presenting cells expressing AFP158-166 peptide and interleukin-15 activate AFP-specific cytotoxic T lymphocytes

Artificial antigen-presenting cells expressing AFP158-166 peptide and interleukin-15 activate AFP-specific cytotoxic T lymphocytes

https://doi.org/10.18632/oncotarget.8198

Longhao Sun, Hao Guo, Ruoyu Jiang, Li Lu, Tong Liu, Zhixiang Zhang,  and Xianghui He
17579-17590
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Research Papers: Autophagy and Cell Death

The multifaceted role of autophagy in tumor evasion from immune surveillance

The multifaceted role of autophagy in tumor evasion from immune surveillance

https://doi.org/10.18632/oncotarget.7540

Bassam Janji, Elodie Viry, Etienne Moussay, Jérôme Paggetti, Tsolère Arakelian, Takouhie Mgrditchian, Yosra Messai, Muhammad Zaeem Noman, Kris Van Moer, Meriem Hasmim, Fathia Mami-Chouaib, Guy Berchem,  and Salem Chouaib
17591-17607
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Research Papers: Chromosome

OncoBinder facilitates interpretation of proteomic interaction data by capturing coactivation pairs in cancer

OncoBinder facilitates interpretation of proteomic interaction data by capturing coactivation pairs in cancer

https://doi.org/10.18632/oncotarget.7305

Samya Van Coillie, Lunxi Liang, Yao Zhang, Huanbin Wang, Jing-Yuan Fang,  and Jie Xu
17608-17615
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Reviews

Therapeutic opportunities in Ewing sarcoma: EWS-FLI inhibition via LSD1 targeting

Therapeutic opportunities in Ewing sarcoma: EWS-FLI inhibition via LSD1 targeting

https://doi.org/10.18632/oncotarget.7124

Emily R. Theisen, Kathleen I. Pishas, Ranajeet S. Saund,  and Stephen L. Lessnick
17616-17630
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DARPP-32: from neurotransmission to cancer

DARPP-32: from neurotransmission to cancer

https://doi.org/10.18632/oncotarget.7268

Abbes Belkhiri, Shoumin Zhu,  and Wael El-Rifai
17631-17640
Abstract  |  PDF  |  HTML  |  Order a Reprint

Functional role of autophagy in gastric cancer

Functional role of autophagy in gastric cancer

https://doi.org/10.18632/oncotarget.7508

Hao-ran Qian,  and Yi Yang
17641-17651
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Research Papers

Oncogenic roles of TOPK and MELK, and effective growth suppression by small molecular inhibitors in kidney cancer cells

Oncogenic roles of TOPK and MELK, and effective growth suppression by small molecular inhibitors in kidney cancer cells

https://doi.org/10.18632/oncotarget.7755

Taigo Kato, Hiroyuki Inoue, Seiya Imoto, Yoshinori Tamada, Takashi Miyamoto, Yo Matsuo, Yusuke Nakamura,  and Jae-Hyun Park
17652-17664
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

BRAF inhibitor resistance enhances vulnerability to arginine deprivation in melanoma

BRAF inhibitor resistance enhances vulnerability to arginine deprivation in melanoma

https://doi.org/10.18632/oncotarget.6882

Ying-Ying Li, Chunjing Wu, Shu-Mei Chen, Sumedh S. Shah, Medhi Wangpaichitr, Lynn G. Feun, Macus T. Kuo, Miguel Suarez, Jeffrey Prince,  and Niramol Savaraj
17665-17680
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Increased hepatic receptor interacting protein kinase 3 expression due to impaired proteasomal functions contributes to alcohol-induced steatosis and liver injury

Increased hepatic receptor interacting protein kinase 3 expression due to impaired proteasomal functions contributes to alcohol-induced steatosis and liver injury

https://doi.org/10.18632/oncotarget.6893

Shaogui Wang, Hong-Min Ni, Kenneth Dorko, Sean C. Kumer, Timothy M. Schmitt, Atta Nawabi, Masaaki Komatsu, Heqing Huang,  and Wen-Xing Ding
17681-17698
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DDRI-9: a novel DNA damage response inhibitor that blocks mitotic progression

DDRI-9: a novel DNA damage response inhibitor that blocks mitotic progression

https://doi.org/10.18632/oncotarget.7135

Dong Wha Jun, Mihwa Hwang, Yun-Hee Kim, Kyung-Tae Kim, Sunshin Kim,  and Chang-Hun Lee
17699-17710
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Mutanome and expression of immune response genes in microsatellite stable colon cancer

Mutanome and expression of immune response genes in microsatellite stable colon cancer

https://doi.org/10.18632/oncotarget.7293

Rebeca Sanz-Pamplona, Raúl Gil-Hoyos, Adriana López-Doriga, M. Henar Alonso, Susanna Aussó, David G. Molleví, Cristina Santos, Xavier Sanjuán, Ramón Salazar, Ramón Alemany,  and Víctor Moreno
17711-17725
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

14-3-3σ regulation of and interaction with YAP1 in acquired gemcitabine resistance via promoting ribonucleotide reductase expression

14-3-3σ regulation of and interaction with YAP1 in acquired gemcitabine resistance via promoting ribonucleotide reductase expression

https://doi.org/10.18632/oncotarget.7394

Li Qin, Zizheng Dong,  and Jian-Ting Zhang
17726-17736
Abstract  |  PDF  |  HTML  |  Order a Reprint

Low tristetraprolin expression promotes cell proliferation and predicts poor patients outcome in pancreatic cancer

Low tristetraprolin expression promotes cell proliferation and predicts poor patients outcome in pancreatic cancer

https://doi.org/10.18632/oncotarget.7397

Zi-Ran Wei, Chao Liang, Dan Feng, Ya-Jun Cheng, Wei-Min Wang, De-Jun Yang, Yue-Xiang Wang,  and Qing-Ping Cai
17737-17750
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CD133 promotes gallbladder carcinoma cell migration through activating Akt phosphorylation

CD133 promotes gallbladder carcinoma cell migration through activating Akt phosphorylation

https://doi.org/10.18632/oncotarget.7474

Chen Li, Cong Wang, Yang Xing, Jiaojiao Zhen,  and Zhilong Ai
17751-17759
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β2-adrenogenic signaling regulates NNK-induced pancreatic cancer progression via upregulation of HIF-1α

β2-adrenogenic signaling regulates NNK-induced pancreatic cancer progression via upregulation of HIF-1α

https://doi.org/10.18632/oncotarget.5677

Dong Zhang, Jianjun Lei, Jiguang Ma, Xin Chen, Liang Sheng, Zhengdong Jiang, Ligang Nan, Qinhong Xu, Wanxing Duan, Zheng Wang, Xuqi Li, Zheng Wu, Erxi Wu, Qingyong Ma,  and Xiongwei Huo
17760-17772
Abstract  |  PDF  |  HTML  |  Order a Reprint

Cell-surface markers for colon adenoma and adenocarcinoma

Cell-surface markers for colon adenoma and adenocarcinoma

https://doi.org/10.18632/oncotarget.7402

Kamini Sewda, Domenico Coppola, Steven Enkemann, Binglin Yue, Jongphil Kim, Alexis S. Lopez, Jonathan W. Wojtkowiak, Valerie E. Stark, Brian Morse, David Shibata, Shivakumar Vignesh,  and David L. Morse
17773-17789
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Nuclear β-arrestin1 is a critical cofactor of hypoxia-inducible factor-1α signaling in endothelin-1-induced ovarian tumor progression

Nuclear β-arrestin1 is a critical cofactor of hypoxia-inducible factor-1α signaling in endothelin-1-induced ovarian tumor progression

https://doi.org/10.18632/oncotarget.7461

Roberta Cianfrocca, Piera Tocci, Laura Rosanò, Valentina Caprara, Rosanna Sestito, Valeriana Di Castro,  and Anna Bagnato
17790-17804
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Role and mechanism of miR-222 in arsenic-transformed cells for inducing tumor growth

Role and mechanism of miR-222 in arsenic-transformed cells for inducing tumor growth

https://doi.org/10.18632/oncotarget.7525

Min Wang, Xin Ge, Jitai Zheng, Dongmei Li, Xue Liu, Lin Wang, Chengfei Jiang, Zhumei Shi, Lianju Qin, Jiayin Liu, Hushan Yang, Ling-Zhi Liu, Jun He, Linlin Zhen,  and Bing-Hua Jiang
17805-17814
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

AMPK and PKA interaction in the regulation of survival of liver cancer cells subjected to glucose starvation

AMPK and PKA interaction in the regulation of survival of liver cancer cells subjected to glucose starvation

https://doi.org/10.18632/oncotarget.7404

Anabela C. Ferretti, Facundo M. Tonucci, Florencia Hidalgo, Evangelina Almada, Maria C. Larocca,  and Cristián Favre
17815-17828
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mDia1 regulates breast cancer invasion by controlling membrane type 1-matrix metalloproteinase localization

mDia1 regulates breast cancer invasion by controlling membrane type 1-matrix metalloproteinase localization

https://doi.org/10.18632/oncotarget.7429

Daehwan Kim, Jangho Jung, Eunae You, Panseon Ko, Somi Oh,  and Sangmyung Rhee
17829-17843
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Melanin content in melanoma metastases affects the outcome of radiotherapy

Melanin content in melanoma metastases affects the outcome of radiotherapy

https://doi.org/10.18632/oncotarget.7528

Anna A. Brożyna, Wojciech Jóźwicki, Krzysztof Roszkowski, Jan Filipiak,  and Andrzej T. Slominski
17844-17853
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Upregulated WDR26 serves as a scaffold to coordinate PI3K/ AKT pathway-driven breast cancer cell growth, migration, and invasion

Upregulated WDR26 serves as a scaffold to coordinate PI3K/ AKT pathway-driven breast cancer cell growth, migration, and invasion

https://doi.org/10.18632/oncotarget.7439

Yuanchao Ye, Xiaoyun Tang, Zhizeng Sun,  and Songhai Chen
17854-17869
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Chemopreventive activity of GEN-27, a genistein derivative, in colitis-associated cancer is mediated by p65-CDX2-β-catenin axis

Chemopreventive activity of GEN-27, a genistein derivative, in colitis-associated cancer is mediated by p65-CDX2-β-catenin axis

https://doi.org/10.18632/oncotarget.7554

Qianming Du, Yajing Wang, Chao Liu, Hong Wang, Huimin Fan, Yan Li, Jianing Wang, Xu Zhang, Jinrong Lu, Hui Ji,  and Rong Hu
17870-17884
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

CEACAM1 and MICA as novel serum biomarkers in patients with acute and recurrent pericarditis

CEACAM1 and MICA as novel serum biomarkers in patients with acute and recurrent pericarditis

https://doi.org/10.18632/oncotarget.7530

Gal Markel, Massimo Imazio, Nira Koren-Morag, Gilli Galore-Haskel, Jacob Schachter, Michal Besser, Davide Cumetti, Silvia Maestroni, Arie Altman, Yehuda Shoenfeld, Antonio Brucato,  and Yehuda Adler
17885-17895
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Tumor size is an independent risk predictor for metachronous colorectal cancer

Tumor size is an independent risk predictor for metachronous colorectal cancer

https://doi.org/10.18632/oncotarget.7555

Takaharu Kato, Sergio Alonso, Yuta Muto, Manuel Perucho,  and Toshiki Rikiyama
17896-17904
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PKCδ regulates integrin αVβ3 expression and transformed growth of K-ras dependent lung cancer cells

PKCδ regulates integrin αVβ3 expression and transformed growth of K-ras dependent lung cancer cells

https://doi.org/10.18632/oncotarget.7560

Jennifer M. Symonds, Angela M. Ohm, Aik-Choon Tan,  and Mary E. Reyland
17905-17919
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

The homing and inhibiting effects of hNSCs-BMP4 on human glioma stem cells

The homing and inhibiting effects of hNSCs-BMP4 on human glioma stem cells

https://doi.org/10.18632/oncotarget.7472

Shuang Liu, Feng Yin, Mingming Zhao, Chunhui Zhou, Junlin Ren, Qiming Huang, Zhongming Zhao, Ramkrishna Mitra, Wenhong Fan,  and Ming Fan
17920-17931
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“Triple positive” early breast cancer: an observational multicenter retrospective analysis of outcome

“Triple positive” early breast cancer: an observational multicenter retrospective analysis of outcome

https://doi.org/10.18632/oncotarget.7480

Patrizia Vici, Laura Pizzuti, Isabella Sperduti, Antonio Frassoldati, Clara Natoli, Teresa Gamucci, Silverio Tomao, Andrea Michelotti, Luca Moscetti, Stefania Gori, Editta Baldini, Francesco Giotta, Alessandra Cassano, Daniele Santini, Diana Giannarelli, Luigi Di Lauro, Domenico Cristiano Corsi, Paolo Marchetti, Valentina Sini, Domenico Sergi, Maddalena Barba, Marcello Maugeri-Saccà, Michelangelo Russillo, Lucia Mentuccia, Loretta D’Onofrio, Laura Iezzi, Angelo Fedele Scinto, Lucia Da Ros, Ilaria Bertolini, Maria Luisa Basile, Valentina Rossi, Ruggero De Maria,  and Filippo Montemurro
17932-17944
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Ultraviolet radiation-induced tumor necrosis factor alpha, which is linked to the development of cutaneous SCC, modulates differential epidermal microRNAs expression

Ultraviolet radiation-induced tumor necrosis factor alpha, which is linked to the development of cutaneous SCC, modulates differential epidermal microRNAs expression

https://doi.org/10.18632/oncotarget.7595

Ashok Singh, Estelle Willems, Anupama Singh, Bilal Bin Hafeez, Irene M. Ong, Suresh L. Mehta,  and Ajit Kumar Verma
17945-17956
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Methylation of DACT2 accelerates esophageal cancer development by activating Wnt signaling

Methylation of DACT2 accelerates esophageal cancer development by activating Wnt signaling

https://doi.org/10.18632/oncotarget.7647

Meiying Zhang, Enqiang Linghu, Qimin Zhan, Tao He, Baoping Cao, Malcolm V. Brock, James G. Herman, Rong Xiang,  and Mingzhou Guo
17957-17969
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Rac1b enhances cell survival through activation of the JNK2/c-JUN/Cyclin-D1 and AKT2/MCL1 pathways

Rac1b enhances cell survival through activation of the JNK2/c-JUN/Cyclin-D1 and AKT2/MCL1 pathways

https://doi.org/10.18632/oncotarget.7602

Gang Li, Li Ying, Hong Wang, Si-Si Wei, Jie Chen, Yi-He Chen, Wei-Ping Xu, Qi-Qiang Jie, Qing Zhou, Yi-Gang Li, Yi-Dong Wei,  and Yue-Peng Wang
17970-17985
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Analysis of differential β variable region of T cell receptor expression and NAV3/TNFRSF1B gene mutation in mycosis fungoides

Analysis of differential β variable region of T cell receptor expression and NAV3/TNFRSF1B gene mutation in mycosis fungoides

https://doi.org/10.18632/oncotarget.7673

Hongzhou Cui, Jie Liu, Li Li, Jingyu Ren, Shuping Guo,  and Li Bai
17986-17990
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Loss of tumor suppressor Merlin results in aberrant activation of Wnt/β-catenin signaling in cancer

Loss of tumor suppressor Merlin results in aberrant activation of Wnt/β-catenin signaling in cancer

https://doi.org/10.18632/oncotarget.7494

Adam K. Morrow, Shamik Das, Erhong Meng, Mitchell E. Menezes, Sarah K. Bailey, Brandon J. Metge, Donald J. Buchsbaum, Rajeev S. Samant,  and Lalita A. Shevde
17991-18005
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A network-based method for identifying prognostic gene modules in lung squamous carcinoma

A network-based method for identifying prognostic gene modules in lung squamous carcinoma

https://doi.org/10.18632/oncotarget.7632

Lin Feng, Run Tong, Xiaohong Liu, Kaitai Zhang, Guiqi Wang, Lei Zhang, Ning An,  and Shujun Cheng
18006-18020
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PLA2G16 promotes osteosarcoma metastasis and drug resistance via the MAPK pathway

PLA2G16 promotes osteosarcoma metastasis and drug resistance via the MAPK pathway

https://doi.org/10.18632/oncotarget.7694

Lin Li, Shoulei Liang, Amanda R. Wasylishen, Yanqin Zhang, Xueli Yang, Bingzheng Zhou, Luling Shan, Xiuxin Han, Tianyang Mu, Guowen Wang,  and Shunbin Xiong
18021-18035
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Stratifying diffuse large B-cell lymphoma patients treated with chemoimmunotherapy: GCB/non-GCB by immunohistochemistry is still a robust and feasible marker

Stratifying diffuse large B-cell lymphoma patients treated with chemoimmunotherapy: GCB/non-GCB by immunohistochemistry is still a robust and feasible marker

https://doi.org/10.18632/oncotarget.7495

Ana Batlle-López, Sonia González de Villambrosía, Mazorra Francisco, Sefora Malatxeberria, Anabel Sáez, Carlos Montalban, Lydia Sánchez, Juan F. Garcia, Eva González-Barca, Andrés López-Hernández, MC Ruiz-Marcellan, Manuela Mollejo, Carlos Grande, Kristy L. Richards, Eric D. Hsi, Alexandar Tzankov, Carlo Visco, Zijun Y. Xu-Monette, Xin Cao, Ken H. Young, Miguel Angel Piris, Eulogio Conde,  and Santiago Montes-Moreno
18036-18049
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

EF24 induces ROS-mediated apoptosis via targeting thioredoxin reductase 1 in gastric cancer cells

EF24 induces ROS-mediated apoptosis via targeting thioredoxin reductase 1 in gastric cancer cells

https://doi.org/10.18632/oncotarget.7633

Peng Zou, Yiqun Xia, Weiqian Chen, Xi Chen, Shilong Ying, Zhiguo Feng, Tongke Chen, Qingqing Ye, Zhe Wang, Chenyu Qiu, Shulin Yang,  and Guang Liang
18050-18064
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Predicting hot spots in protein interfaces based on protrusion index, pseudo hydrophobicity and electron-ion interaction pseudopotential features

Predicting hot spots in protein interfaces based on protrusion index, pseudo hydrophobicity and electron-ion interaction pseudopotential features

https://doi.org/10.18632/oncotarget.7695

Junfeng Xia, Zhenyu Yue, Yunqiang Di, Xiaolei Zhu,  and Chun-Hou Zheng
18065-18075
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Mitotic cell death caused by follistatin-like 1 inhibition is associated with up-regulated Bim by inactivated Erk1/2 in human lung cancer cells

Mitotic cell death caused by follistatin-like 1 inhibition is associated with up-regulated Bim by inactivated Erk1/2 in human lung cancer cells

https://doi.org/10.18632/oncotarget.6729

Kieun Bae, Kyoung Eun Park, Jihye Han, Jongkwang Kim, Kyungtae Kim,  and Kyong-Ah Yoon
18076-18084
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MACC1 mediates acetylcholine-induced invasion and migration by human gastric cancer cells

MACC1 mediates acetylcholine-induced invasion and migration by human gastric cancer cells

https://doi.org/10.18632/oncotarget.7634

Ting Yang, Wanming He, Fei Cui, Jianling Xia, Rui Zhou, Zhenzhen Wu, Yang Zhao,  and Min Shi
18085-18094
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Serum sphingolipidomic analyses reveal an upregulation of C16- ceramide and sphingosine-1-phosphate in hepatocellular carcinoma

Serum sphingolipidomic analyses reveal an upregulation of C16- ceramide and sphingosine-1-phosphate in hepatocellular carcinoma

https://doi.org/10.18632/oncotarget.7741

Georgios Grammatikos, Niklas Schoell, Nerea Ferreirós, Dimitra Bon, Eva Herrmann, Harald Farnik, Verena Köberle, Albrecht Piiper, Stefan Zeuzem, Bernd Kronenberger, Oliver Waidmann,  and Josef Pfeilschifter
18095-18105
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Deletion of IL-33R attenuates VEGF expression and enhances necrosis in mammary carcinoma

Deletion of IL-33R attenuates VEGF expression and enhances necrosis in mammary carcinoma

https://doi.org/10.18632/oncotarget.7635

Milos Z. Milosavljevic, Ivan P. Jovanovic, Nada N. Pejnovic, Slobodanka L. J. Mitrovic, Nebojsa N. Arsenijevic, Bojana J. Simovic Markovic,  and Miodrag L. Lukic
18106-18115
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An EBV recombinant deleted for residues 130-159 in EBNA3C can deregulate p53/Mdm2 and Cyclin D1/CDK6 which results in apoptosis and reduced cell proliferation

An EBV recombinant deleted for residues 130-159 in EBNA3C can deregulate p53/Mdm2 and Cyclin D1/CDK6 which results in apoptosis and reduced cell proliferation

https://doi.org/10.18632/oncotarget.7502

Sanket Kumar Shukla, Hem Chandra Jha, Darine W. El-Naccache,  and Erle S. Robertson
18116-18134
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Stereotactic radiation therapy for oligometastases or oligorecurrence within mediastinal lymph nodes

Stereotactic radiation therapy for oligometastases or oligorecurrence within mediastinal lymph nodes

https://doi.org/10.18632/oncotarget.7636

Huan-Huan Wang, Nicholas G. Zaorsky, Mao-Bin Meng, Xian-Liang Zeng, Lei Deng, Yong-Chun Song, Hong-Qing Zhuang, Feng-Tong Li, Lu-Jun Zhao, Zhi-Yong Yuan, Ping Wang,  and Xi-Shan Hao
18135-18145
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Pancreatic stellate cells contribute pancreatic cancer pain via activation of sHH signaling pathway

Pancreatic stellate cells contribute pancreatic cancer pain via activation of sHH signaling pathway

https://doi.org/10.18632/oncotarget.7776

Liang Han, Jiguang Ma, Wanxing Duan, Lun Zhang, Shuo Yu, Qinhong Xu, Jianjun Lei, Xuqi Li, Zheng Wang, Zheng Wu, Jason H. Huang, Erxi Wu, Qingyong Ma,  and Zhenhua Ma
18146-18158
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

CHK1 regulates NF-κB signaling upon DNA damage in p53- deficient cells and associated tumor-derived microvesicles

CHK1 regulates NF-κB signaling upon DNA damage in p53- deficient cells and associated tumor-derived microvesicles

https://doi.org/10.18632/oncotarget.7566

Brittany L. Carroll, Michael J. Pulkoski-Gross, Yusuf A. Hannun,  and Lina M. Obeid
18159-18170
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Preclinical evaluation of biomarkers associated with antitumor activity of MELK inhibitor

Preclinical evaluation of biomarkers associated with antitumor activity of MELK inhibitor

https://doi.org/10.18632/oncotarget.7685

Suyoun Chung, Kyoko Kijima, Aiko Kudo, Yoshiko Fujisawa, Yosuke Harada, Akiko Taira, Naofumi Takamatsu, Takashi Miyamoto, Yo Matsuo,  and Yusuke Nakamura
18171-18182
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Galectin signatures contribute to the heterogeneity of breast cancer and provide new prognostic information and therapeutic targets

Galectin signatures contribute to the heterogeneity of breast cancer and provide new prognostic information and therapeutic targets

https://doi.org/10.18632/oncotarget.7784

Andrée-Anne Grosset, Marilyne Labrie, Maria Claudia Vladoiu, Einas M Yousef, Louis Gaboury,  and Yves St-Pierre
18183-18203
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Inhibition of protein kinase CK2 by CX-5011 counteracts imatinib-resistance preventing rpS6 phosphorylation in chronic myeloid leukaemia cells: new combined therapeutic strategies

Inhibition of protein kinase CK2 by CX-5011 counteracts imatinib-resistance preventing rpS6 phosphorylation in chronic myeloid leukaemia cells: new combined therapeutic strategies

https://doi.org/10.18632/oncotarget.7569

Valentina Salizzato, Christian Borgo, Luca Cesaro, Lorenzo A. Pinna,  and Arianna Donella-Deana
18204-18218
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The role and potential mechanisms of LncRNA-TATDN1 on metastasis and invasion of non-small cell lung cancer

The role and potential mechanisms of LncRNA-TATDN1 on metastasis and invasion of non-small cell lung cancer

https://doi.org/10.18632/oncotarget.7788

Niu Zequn, Zhang Xuemei, Li Wei, Ming Zongjuan, Zhong Yujie, Hou Yanli, Zhang Yuping, Meng Xia, Wang Wei, Deng Wenjing, Fan Na,  and Yang Shuanying
18219-18228
Abstract  |  PDF  |  HTML  |  Order a Reprint

Liver fatty acid-binding protein (L-FABP) promotes cellular angiogenesis and migration in hepatocellular carcinoma

Liver fatty acid-binding protein (L-FABP) promotes cellular angiogenesis and migration in hepatocellular carcinoma

https://doi.org/10.18632/oncotarget.7571

Chung-Yu Ku, Yu-Huei Liu, Hsuan-Yuan Lin, Shao-Chun Lu,  and Jung-Yaw Lin
18229-18246
Abstract  |  PDF  |  HTML  |  Order a Reprint

MiR-206 inhibits HGF-induced epithelial-mesenchymal transition and angiogenesis in non-small cell lung cancer via c-Met /PI3k/ Akt/mTOR pathway

MiR-206 inhibits HGF-induced epithelial-mesenchymal transition and angiogenesis in non-small cell lung cancer via c-Met /PI3k/ Akt/mTOR pathway

https://doi.org/10.18632/oncotarget.7570

Qing-yong Chen, De-min Jiao, Yu-quan Wu, Jun Chen, Jian Wang, Xia-li Tang, Hao Mou, Hui-zhen Hu, Jia Song, Jie Yan, Li-jun Wu, Jianyan Chen,  and Zhiwei Wang
18247-18261
Abstract  |  PDF  |  HTML  |  Order a Reprint

Targeting the insulin growth factor-1 receptor with fluorescent antibodies enables high resolution imaging of human pancreatic cancer in orthotopic mouse models

Targeting the insulin growth factor-1 receptor with fluorescent antibodies enables high resolution imaging of human pancreatic cancer in orthotopic mouse models

https://doi.org/10.18632/oncotarget.7576

Jeong Youp Park, Jin Young Lee, Yong Zhang, Robert M. Hoffman,  and Michael Bouvet
18262-18268
Abstract  |  PDF  |  HTML  |  Order a Reprint

Tumor deposits counted as positive lymph nodes in TNM staging for advanced colorectal cancer: a retrospective multicenter study

Tumor deposits counted as positive lymph nodes in TNM staging for advanced colorectal cancer: a retrospective multicenter study

https://doi.org/10.18632/oncotarget.7756

Jun Li, Shengke Yang, Junjie Hu, Hao Liu, Feng Du, Jie Yin, Sai Liu, Ci Li, Shasha Xing, Jiatian Yuan, Bo Lv, Jun Fan, Shusheng Leng, Xin Zhang,  and Bing Wang
18269-18279
Abstract  |  PDF  |  HTML  |  Order a Reprint

Dicer suppresses the malignant phenotype in VHL-deficient clear cell renal cell carcinoma by inhibiting HIF-2α

Dicer suppresses the malignant phenotype in VHL-deficient clear cell renal cell carcinoma by inhibiting HIF-2α

https://doi.org/10.18632/oncotarget.7807

Yang Fan, Hongzhao Li, Xin Ma, Yu Gao, Xu Bao, Qingshan Du, Minghui Ma, Kan Liu, Yuanxin Yao, Qingbo Huang, Yu Zhang,  and Xu Zhang
18280-18294
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

A novel double-negative feedback loop between miR-489 and the HER2-SHP2-MAPK signaling axis regulates breast cancer cell proliferation and tumor growth

A novel double-negative feedback loop between miR-489 and the HER2-SHP2-MAPK signaling axis regulates breast cancer cell proliferation and tumor growth

https://doi.org/10.18632/oncotarget.7577

Yogin Patel, Nirav Shah, Ji Shin Lee, Eleni Markoutsa, Chunfa Jie, Shou Liu, Rachel Botbyl, David Reisman, Peisheng Xu,  and Hexin Chen
18295-18308
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

A nuclear-directed human pancreatic ribonuclease (PE5) targets the metabolic phenotype of cancer cells

A nuclear-directed human pancreatic ribonuclease (PE5) targets the metabolic phenotype of cancer cells

https://doi.org/10.18632/oncotarget.7579

Anna Vert, Jessica Castro, Marc Ribó, Antoni Benito,  and Maria Vilanova
18309-18324
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Class II phosphoinositide 3-kinase C2β regulates a novel signaling pathway involved in breast cancer progression

Class II phosphoinositide 3-kinase C2β regulates a novel signaling pathway involved in breast cancer progression

https://doi.org/10.18632/oncotarget.7761

Anissa Chikh, Riccardo Ferro, Jonathan J. Abbott, Roberto Piñeiro, Richard Buus, Manuela Iezzi, Francesca Ricci, Daniele Bergamaschi, Paola Ostano, Giovanna Chiorino, Rossano Lattanzio, Massimo Broggini, Mauro Piantelli, Tania Maffucci,  and Marco Falasca
18325-18345
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

BRAF and TERT promoter mutations in the aggressiveness of papillary thyroid carcinoma: a study of 653 patients

BRAF and TERT promoter mutations in the aggressiveness of papillary thyroid carcinoma: a study of 653 patients

https://doi.org/10.18632/oncotarget.7811

Langping Jin, Endong Chen, Siyang Dong, Yefeng Cai, Xiangjian Zhang, Yili Zhou, Ruichao Zeng, Fan Yang, Chuanmeng Pan, Yehuan Liu, Weili Wu, Mingzhao Xing, Xiaohua Zhang,  and Ouchen Wang
18346-18355
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

SH3-domain binding protein 1 in the tumor microenvironment promotes hepatocellular carcinoma metastasis through WAVE2 pathway

SH3-domain binding protein 1 in the tumor microenvironment promotes hepatocellular carcinoma metastasis through WAVE2 pathway

https://doi.org/10.18632/oncotarget.7786

Yiming Tao, Kuan Hu, Fengbo Tan, Sai Zhang, Ming Zhou, Jia Luo,  and Zhiming Wang
18356-18370
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Ran Binding Protein 9 (RanBP9) is a novel mediator of cellular DNA damage response in lung cancer cells

Ran Binding Protein 9 (RanBP9) is a novel mediator of cellular DNA damage response in lung cancer cells

https://doi.org/10.18632/oncotarget.7813

Dario Palmieri, Mario Scarpa, Anna Tessari, Rexhep Uka, Foued Amari, Cindy Lee, Timothy Richmond, Claudia Foray, Tyler Sheetz, Ashley Braddom, Christin E. Burd, Jeffrey D. Parvin, Thomas Ludwig, Carlo M. Croce,  and Vincenzo Coppola
18371-18383
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

125I brachytherapy in the palliation of painful bone metastases from lung cancer after failure or rejection of conventional treatments

125I brachytherapy in the palliation of painful bone metastases from lung cancer after failure or rejection of conventional treatments

https://doi.org/10.18632/oncotarget.7584

Zhanwang Xiang, Zhiqiang Mo, Guohong Li, Saba Gilani, Zhihui Zhong, Burkhard Hinz, Fujun Zhang,  and Fei Gao
18384-18393
Abstract  |  PDF  |  HTML  |  Order a Reprint

Identification of FGF19 as a prognostic marker and potential driver gene of lung squamous cell carcinomas in Chinese smoking patients

Identification of FGF19 as a prognostic marker and potential driver gene of lung squamous cell carcinomas in Chinese smoking patients

https://doi.org/10.18632/oncotarget.7817

Qiang Tan, Fan Li, Guan Wang, Weiliang Xia, Ziming Li, Xiaomin Niu, Wenxiang Ji, Hong Yuan, Qiang Xu, Qingquan Luo, Jie Zhang,  and Shun Lu
18394-18402
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Systematic characterization of lncRNAs’ cell-to-cell expression heterogeneity in glioblastoma cells

Systematic characterization of lncRNAs’ cell-to-cell expression heterogeneity in glioblastoma cells

https://doi.org/10.18632/oncotarget.7580

Dekang Lv, Xiang Wang, Jun Dong, Yan Zhuang, Shuyu Huang, Peter C.K. Leung, Puxiang Chen, Xiaodong Li, Bo Zhang, Zhiguang Li,  and Bilian Jin
18403-18414
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Nuclear heat shock protein 110 expression is associated with poor prognosis and chemotherapy resistance in gastric cancer

Nuclear heat shock protein 110 expression is associated with poor prognosis and chemotherapy resistance in gastric cancer

https://doi.org/10.18632/oncotarget.7821

Akiharu Kimura, Kyoichi Ogata, Bolag Altan, Takehiko Yokobori, Munenori Ide, Erito Mochiki, Yoshitaka Toyomasu, Norimichi Kogure, Toru Yanoma, Masaki Suzuki, Tuya Bai, Tetsunari Oyama,  and Hiroyuki Kuwano
18415-18423
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Preclinical evidence of multiple mechanisms underlying trastuzumab resistance in gastric cancer

Preclinical evidence of multiple mechanisms underlying trastuzumab resistance in gastric cancer

https://doi.org/10.18632/oncotarget.7575

Chiara Arienti, Michele Zanoni, Sara Pignatta, Alberto Del Rio, Silvia Carloni, Michela Tebaldi, Gianluca Tedaldi,  and Anna Tesei
18424-18439
Abstract  |  PDF  |  HTML  |  Order a Reprint

Alkaline ceramidase 2 and its bioactive product sphingosine are novel regulators of the DNA damage response

Alkaline ceramidase 2 and its bioactive product sphingosine are novel regulators of the DNA damage response

https://doi.org/10.18632/oncotarget.7825

Ruijuan Xu, Kai Wang, Izolda Mileva, Yusuf A. Hannun, Lina M. Obeid,  and Cungui Mao
18440-18457
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Prognostic impact of serum and tissue MMP-9 in non-small cell lung cancer: a systematic review and meta-analysis

Prognostic impact of serum and tissue MMP-9 in non-small cell lung cancer: a systematic review and meta-analysis

https://doi.org/10.18632/oncotarget.7607

Liang Gong, Dan Wu, Jianding Zou, Jianqiang Chen, Liangyu Chen, Yun Chen, Chao Ni,  and Hongjun Yuan
18458-18468
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Dietary pterostilbene is a novel MTA1-targeted chemopreventive and therapeutic agent in prostate cancer

Dietary pterostilbene is a novel MTA1-targeted chemopreventive and therapeutic agent in prostate cancer

https://doi.org/10.18632/oncotarget.7841

Swati Dhar, Avinash Kumar, Liangfen Zhang, Agnes M. Rimando, Janice M. Lage, Jack R. Lewin, Azeddine Atfi, Xu Zhang,  and Anait S. Levenson
18469-18484
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Detection of aberrant methylation of a six-gene panel in serum DNA for diagnosis of breast cancer

Detection of aberrant methylation of a six-gene panel in serum DNA for diagnosis of breast cancer

https://doi.org/10.18632/oncotarget.7608

Ming Shan, Huizi Yin, Junnan Li, Xiaobo Li, Dong Wang, Yonghui Su, Ming Niu, Zhenbin Zhong, Ji Wang, Xianyu Zhang, Wenli Kang,  and Da Pang
18485-18494
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Cdc7 is a potent anti-cancer target in pancreatic cancer due to abrogation of the DNA origin activation checkpoint

Cdc7 is a potent anti-cancer target in pancreatic cancer due to abrogation of the DNA origin activation checkpoint

https://doi.org/10.18632/oncotarget.7611

Matthew T. Huggett, Slavica Tudzarova, Ian Proctor, Marco Loddo, Margaret G. Keane, Kai Stoeber, Gareth H. Williams,  and Stephen P. Pereira
18495-18507
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Transformation of the tumour microenvironment by a CD40 agonist antibody correlates with improved responses to PD-L1 blockade in a mouse orthotopic pancreatic tumour model

Transformation of the tumour microenvironment by a CD40 agonist antibody correlates with improved responses to PD-L1 blockade in a mouse orthotopic pancreatic tumour model

https://doi.org/10.18632/oncotarget.7610

Nadia M. Luheshi, Jane Coates-Ulrichsen, James Harper, Stefanie Mullins, Michal G. Sulikowski, Philip Martin, Lee Brown, Arthur Lewis, Gareth Davies, Michelle Morrow,  and Robert W. Wilkinson
18508-18520
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Amplexicaule A exerts anti-tumor effects by inducing apoptosis in human breast cancer

Amplexicaule A exerts anti-tumor effects by inducing apoptosis in human breast cancer

https://doi.org/10.18632/oncotarget.7848

Meixian Xiang, Hanwen Su, Guangwen Shu, Dingrong Wan, Feng He, Morgann Loaec, Yali Ding, Jun Li, Sinisa Dovat, Gaungzhong Yang,  and Chunhua Song
18521-18530
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

MMP2 and MMP9 serum levels are associated with favorable outcome in patients with inflammatory breast cancer treated with bevacizumab-based neoadjuvant chemotherapy in the BEVERLY-2 study

MMP2 and MMP9 serum levels are associated with favorable outcome in patients with inflammatory breast cancer treated with bevacizumab-based neoadjuvant chemotherapy in the BEVERLY-2 study

https://doi.org/10.18632/oncotarget.7612

Emeline Tabouret, François Bertucci, Jean-Yves Pierga, Thierry Petit, Christelle Levy, Jean-Marc Ferrero, Mario Campone, Joseph Gligorov, Florence Lerebours, Henri Roché, Thomas Bachelot, Steven van Laere, Naoto T. Ueno, Yves Toiron, Pascal Finetti, Daniel Birnbaum, Jean-Paul Borg, Patrice Viens, Olivier Chinot,  and Anthony Gonçalves
18531-18540
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

eIF3f reduces tumor growth by directly interrupting clusterin with anti-apoptotic property in cancer cells

eIF3f reduces tumor growth by directly interrupting clusterin with anti-apoptotic property in cancer cells

https://doi.org/10.18632/oncotarget.8105

Ji-Yeon Lee, Hyun-Ji Kim, Seung Bae Rho,  and Seung-Hoon Lee
18541-18557
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Adenoviral targeting of malignant melanoma for fluorescence-guided surgery prevents recurrence in orthotopic nude-mouse models

Adenoviral targeting of malignant melanoma for fluorescence-guided surgery prevents recurrence in orthotopic nude-mouse models

https://doi.org/10.18632/oncotarget.6670

Shuya Yano, Kiyoto Takehara, Hiroyuki Kishimoto, Yasuo Urata, Shunsuke Kagawa, Michael Bouvet, Toshiyoshi Fujiwara,  and Robert M. Hoffman
18558-18572
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Markers of fibroblast-rich tumor stroma and perivascular cells in serous ovarian cancer: Inter- and intra-patient heterogeneity and impact on survival

Markers of fibroblast-rich tumor stroma and perivascular cells in serous ovarian cancer: Inter- and intra-patient heterogeneity and impact on survival

https://doi.org/10.18632/oncotarget.7613

Sara Corvigno, G. Bea A. Wisman, Artur Mezheyeuski, Ate G.J. van der Zee, Hans W. Nijman, Elisabeth Åvall-Lundqvist, Arne Östman,  and Hanna Dahlstrand
18573-18584
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

A pharmacokinetic and safety study of a fixed oral dose of enzastaurin HCl in native Chinese patients with refractory solid tumors and lymphoma

A pharmacokinetic and safety study of a fixed oral dose of enzastaurin HCl in native Chinese patients with refractory solid tumors and lymphoma

https://doi.org/10.18632/oncotarget.7875

Xueying Li, Xiaojie Fang, Su Li, Weijing Zhang, Nong Yang, Yimin Cui, He Huang, Ruiqing Cai, Xiaoting Lin, Xiaohong Fu, Huangming Hong,  and Tongyu Lin
18585-18593
Abstract  |  PDF  |  HTML  |  Order a Reprint

miR-342 overexpression results in a synthetic lethal phenotype in BRCA1-mutant HCC1937 breast cancer cells

miR-342 overexpression results in a synthetic lethal phenotype in BRCA1-mutant HCC1937 breast cancer cells

https://doi.org/10.18632/oncotarget.7617

Elisabetta Crippa, Marco Folini, Marzia Pennati, Nadia Zaffaroni, Marco A. Pierotti,  and Manuela Gariboldi
18594-18604
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Serum-circulating miRNAs predict neuroblastoma progression in mouse model of high-risk metastatic disease

Serum-circulating miRNAs predict neuroblastoma progression in mouse model of high-risk metastatic disease

https://doi.org/10.18632/oncotarget.7615

Satish Kumar Ramraj, Sheeja Aravindan, Dinesh Babu Somasundaram, Terence S. Herman, Mohan Natarajan,  and Natarajan Aravindan
18605-18619
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Nek7 is overexpressed in hepatocellular carcinoma and promotes hepatocellular carcinoma cell proliferation in vitro and in vivo

Nek7 is overexpressed in hepatocellular carcinoma and promotes hepatocellular carcinoma cell proliferation in vitro and in vivo

https://doi.org/10.18632/oncotarget.7620

Lei Zhou, Zhixin Wang, Xinsen Xu, Yong Wan, Kai Qu, Haining Fan, Qiangpu Chen, Xuejun Sun,  and Chang Liu
18620-18630
Abstract  |  PDF  |  HTML  |  Order a Reprint

Genetic scores based on risk-associated single nucleotide polymorphisms (SNPs) can reveal inherited risk of renal cell carcinoma

Genetic scores based on risk-associated single nucleotide polymorphisms (SNPs) can reveal inherited risk of renal cell carcinoma

https://doi.org/10.18632/oncotarget.7623

Yishuo Wu, Ning Zhang, Kaiwen Li, Haitao Chen, Xiaolin Lin, Yang Yu, Yuancheng Gou, Jiangang Hou, Deke Jiang, Rong Na, Xiang Wang, Qiang Ding,  and Jianfeng Xu
18631-18637
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Overexpression of RPS27a contributes to enhanced chemoresistance of CML cells to imatinib by the transactivated STAT3

Overexpression of RPS27a contributes to enhanced chemoresistance of CML cells to imatinib by the transactivated STAT3

https://doi.org/10.18632/oncotarget.7888

Houcai Wang, Bingqian Xie, Yuanyuan Kong, Yi Tao, Guang Yang, Minjie Gao, Hongwei Xu, Fenghuang Zhan, Jumei Shi, Yiwen Zhang,  and Xiaosong Wu
18638-18650
Abstract  |  PDF  |  HTML  |  Order a Reprint

Butein inhibits cell proliferation and induces cell cycle arrest in acute lymphoblastic leukemia via FOXO3a/p27kip1 pathway

Butein inhibits cell proliferation and induces cell cycle arrest in acute lymphoblastic leukemia via FOXO3a/p27kip1 pathway

https://doi.org/10.18632/oncotarget.7624

Yan-Lai Tang, Li-Bin Huang, Wen-Hao Lin, Li-Na Wang, Yun Tian, Dingbo Shi, Jingshu Wang, Ge Qin, Anchuan Li, Yan-Ni Liang, Huan-Juan Zhou, Zhi-Yong Ke, Wenlin Huang, Wuguo Deng,  and Xue-Qun Luo
18651-18664
Abstract  |  PDF  |  HTML  |  Order a Reprint

High expression of myoferlin is associated with poor outcome in oropharyngeal squamous cell carcinoma patients and is inversely associated with HPV-status

High expression of myoferlin is associated with poor outcome in oropharyngeal squamous cell carcinoma patients and is inversely associated with HPV-status

https://doi.org/10.18632/oncotarget.7625

Bhavna Kumar, Nicole V. Brown, Benjamin J. Swanson, Alessandra C. Schmitt, Matthew Old, Enver Ozer, Amit Agrawal, David E. Schuller, Theodoros N. Teknos,  and Pawan Kumar
18665-18677
Abstract  |  PDF  |  HTML  |  Order a Reprint

Langerhans cell histiocytosis in adults: a case report and review of the literature

Langerhans cell histiocytosis in adults: a case report and review of the literature

https://doi.org/10.18632/oncotarget.7892

Cuihong Lian, Yuan Lu,  and Siyuan Shen
18678-18683
Abstract  |  PDF  |  HTML  |  Order a Reprint

Methylation-associated silencing of miR-200b facilitates human hepatocellular carcinoma progression by directly targeting BMI1

Methylation-associated silencing of miR-200b facilitates human hepatocellular carcinoma progression by directly targeting BMI1

https://doi.org/10.18632/oncotarget.7629

Wen-rui Wu, Hong Sun, Rui Zhang, Xian-huan Yu, Xiang-de Shi, Man-sheng Zhu, Hong Zeng, Li-xu Yan, Lei-bo Xu,  and Chao Liu
18684-18693
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Suppression of B-Raf(V600E) cancers by MAPK hyper-activation

Suppression of B-Raf(V600E) cancers by MAPK hyper-activation

https://doi.org/10.18632/oncotarget.7909

Rawan Atiq, Rachel Hertz, Sophia Eldad, Elia Smeir,  and Jacob Bar-Tana
18694-18704
Abstract  |  PDF  |  HTML  |  Order a Reprint

A short-term increase of the postoperative naturally circulating dendritic cells subsets in flurbiprofen-treated patients with esophageal carcinoma undergoing thoracic surgery

A short-term increase of the postoperative naturally circulating dendritic cells subsets in flurbiprofen-treated patients with esophageal carcinoma undergoing thoracic surgery

https://doi.org/10.18632/oncotarget.7669

Di Wang, Xin-lu Yang, Xiao-qing Chai, Shu-hua Shu, Xiao-lin Zhang, Yan-hu Xie, Xin Wei, Yu-jing Wu,  and Wei Wei
18705-18712
Abstract  |  PDF  |  HTML  |  Order a Reprint

microRNAs are differentially regulated between MDM2-positive and negative malignant pleural mesothelioma

microRNAs are differentially regulated between MDM2-positive and negative malignant pleural mesothelioma

https://doi.org/10.18632/oncotarget.7666

Robert Fred Henry Walter, Claudia Vollbrecht, Robert Werner, Jeremias Wohlschlaeger, Daniel Christian Christoph, Kurt Werner Schmid,  and Fabian Dominik Mairinger
18713-18721
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Androgen receptor in Sertoli cells regulates DNA double-strand break repair and chromosomal synapsis of spermatocytes partially through intercellular EGF-EGFR signaling

Androgen receptor in Sertoli cells regulates DNA double-strand break repair and chromosomal synapsis of spermatocytes partially through intercellular EGF-EGFR signaling

https://doi.org/10.18632/oncotarget.7916

Su-Ren Chen, Xiao-Xia Hao, Yan Zhang, Shou-Long Deng, Zhi-Peng Wang, Yu-Qian Wang, Xiu-Xia Wang,  and Yi-Xun Liu
18722-18735
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Inhibition of IRE1α-driven pro-survival pathways is a promising therapeutic application in acute myeloid leukemia

Inhibition of IRE1α-driven pro-survival pathways is a promising therapeutic application in acute myeloid leukemia

https://doi.org/10.18632/oncotarget.7702

Haibo Sun, De-Chen Lin, Xiao Guo, Behzad Kharabi Masouleh, Sigal Gery, Qi Cao, Serhan Alkan, Takayuki Ikezoe, Chie Akiba, Ronald Paquette, Wenwen Chien, Carsten Müller-Tidow, Yang Jing, Konstantin Agelopoulos, Markus Müschen,  and Phillip H. Koeffler
18736-18749
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

The survival benefit and safety of No. 12a lymphadenectomy for gastric cancer patients with distal or total gastrectomy

The survival benefit and safety of No. 12a lymphadenectomy for gastric cancer patients with distal or total gastrectomy

https://doi.org/10.18632/oncotarget.7930

Kun Yang, Hai-Ning Chen, Kai Liu, Wei-Han Zhang, Xin-Zu Chen, Xiao-Long Chen, Zong-Guang Zhou,  and Jian-Kun Hu
18750-18762
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

PDZ-binding kinase/T-LAK cell-originated protein kinase is a target of the fucoidan from brown alga Fucus evanescens in the prevention of EGF-induced neoplastic cell transformation and colon cancer growth

PDZ-binding kinase/T-LAK cell-originated protein kinase is a target of the fucoidan from brown alga Fucus evanescens in the prevention of EGF-induced neoplastic cell transformation and colon cancer growth

https://doi.org/10.18632/oncotarget.7708

Olesia S. Vishchuk, Huimin Sun, Zhe Wang, Svetlana P. Ermakova, JuanJuan Xiao, Tao Lu, PeiPei Xue, Tatyana N. Zvyagintseva, Hua Xiong, Chen Shao, Wei Yan, Qiuhong Duan,  and Feng Zhu
18763-18773
Abstract  |  PDF  |  HTML  |  Order a Reprint

Diagnostic FDG and FDOPA positron emission tomography scans distinguish the genomic type and treatment outcome of neuroblastoma

Diagnostic FDG and FDOPA positron emission tomography scans distinguish the genomic type and treatment outcome of neuroblastoma

https://doi.org/10.18632/oncotarget.7933

Yen-Lin Liu, Meng-Yao Lu, Hsiu-Hao Chang, Ching-Chu Lu, Dong-Tsamn Lin, Shiann-Tarng Jou, Yung-Li Yang, Ya-Ling Lee, Shiu-Feng Huang, Yung-Ming Jeng, Hsinyu Lee, James S. Miser, Kai-Hsin Lin, Yung-Feng Liao, Wen-Ming Hsu,  and Kai-Yuan Tzen
18774-18786
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Point-of-care test for cervical cancer in LMICs

Point-of-care test for cervical cancer in LMICs

https://doi.org/10.18632/oncotarget.7709

Sulma I. Mohammed, Wen Ren, Lisa Flowers, Bartek Rajwa, Carla J. Chibwesha, Groesbeck P. Parham,  and Joseph M.K. Irudayaraj
18787-18797
Abstract  |  PDF  |  HTML  |  Order a Reprint

CtBP1 associates metabolic syndrome and breast carcinogenesis targeting multiple miRNAs

CtBP1 associates metabolic syndrome and breast carcinogenesis targeting multiple miRNAs

https://doi.org/10.18632/oncotarget.7711

Paola De Luca, Guillermo N. Dalton, Georgina D. Scalise, Cristian P. Moiola, Juliana Porretti, Cintia Massillo, Edith Kordon, Kevin Gardner, Florencia Zalazar, Carolina Flumian, Laura Todaro, Elba S. Vazquez, Roberto Meiss,  and Adriana De Siervi
18798-18811
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

PARP6 acts as a tumor suppressor via downregulating Survivin expression in colorectal cancer

PARP6 acts as a tumor suppressor via downregulating Survivin expression in colorectal cancer

https://doi.org/10.18632/oncotarget.7712

Guangying Qi, Yasusei Kudo, Bo Tang, Tian Liu, Shengjian Jin, Jing Liu, Xiaoxu Zuo, Sisi Mi, Wenhuan Shao, Xiaojuan Ma, Takaaki Tsunematsu, Naozumi Ishimaru, Sien Zeng, Masaaki Tatsuka,  and Fumio Shimamoto
18812-18824
Abstract  |  PDF  |  HTML  |  Order a Reprint

An image guided small animal stereotactic radiotherapy system

An image guided small animal stereotactic radiotherapy system

https://doi.org/10.18632/oncotarget.7939

Hao Sha, Thirupandiyur S. Udayakumar, Perry B. Johnson, Nesrin Dogan, Alan Pollack,  and Yidong Yang
18825-18836
Abstract  |  PDF  |  HTML  |  Order a Reprint

High blood sugar levels significantly impact the prognosis of colorectal cancer patients through down-regulation of microRNA-16 by targeting Myb and VEGFR2

High blood sugar levels significantly impact the prognosis of colorectal cancer patients through down-regulation of microRNA-16 by targeting Myb and VEGFR2

https://doi.org/10.18632/oncotarget.7719

I-Ping Yang, Hsiang-Lin Tsai, Ching-Wen Huang, Chien-Yu Lu, Zhi-Feng Miao, Se-Fen Chang, Suh-Hang Hank Juo,  and Jaw-Yuan Wang
18837-18850
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

A combination of trastuzumab and BAG-1 inhibition synergistically targets HER2 positive breast cancer cells

A combination of trastuzumab and BAG-1 inhibition synergistically targets HER2 positive breast cancer cells

https://doi.org/10.18632/oncotarget.7944

Emmanouil Papadakis, Natalia Robson, Alison Yeomans, Sarah Bailey, Stephanie Laversin, Stephen Beers, A. Emre Sayan, Margaret Ashton-Key, Stefan Schwaiger, Hermann Stuppner, Jakob Troppmair, Graham Packham,  and Ramsey Cutress
18851-18864
Abstract  |  PDF  |  HTML  |  Order a Reprint

CXCR4/CXCL12/CXCR7 axis is functional in neuroendocrine tumors and signals on mTOR

CXCR4/CXCL12/CXCR7 axis is functional in neuroendocrine tumors and signals on mTOR

https://doi.org/10.18632/oncotarget.7738

Luisa Circelli, Concetta Sciammarella, Elia Guadagno, Salvatore Tafuto, Marialaura del Basso de Caro, Giovanni Botti, Luciano Pezzullo, Massimo Aria, Valeria Ramundo, Fabiana Tatangelo, Nunzia Simona Losito, Caterina Ieranò, Crescenzo D’Alterio, Francesco Izzo, Gennaro Ciliberto, Annamaria Colao, Antongiulio Faggiano,  and Stefania Scala
18865-18875
Abstract  |  PDF  |  HTML  |  Order a Reprint

Comprehensive genetic testing identifies targetable genomic alterations in most patients with non-small cell lung cancer, specifically adenocarcinoma, single institute investigation

Comprehensive genetic testing identifies targetable genomic alterations in most patients with non-small cell lung cancer, specifically adenocarcinoma, single institute investigation

https://doi.org/10.18632/oncotarget.7739

Janani Vigneswaran, Yi-Hung Carol Tan, Septimiu D. Murgu, Brian M. Won, Kathryn Alexa Patton, Victoria M. Villaflor, Philip C. Hoffman, Thomas Hensing, Kyle D. Hogarth, Renuka Malik, Heber MacMahon, Jeffrey Mueller, Cassie A. Simon, Wickii T. Vigneswaran, Christopher H. Wigfield, Mark K. Ferguson, Aliya N. Husain, Everett E. Vokes,  and Ravi Salgia
18876-18886
Abstract  |  PDF  |  HTML  |  Order a Reprint

Radiation-induced brachial plexopathy in patients with nasopharyngeal carcinoma: a retrospective study

Radiation-induced brachial plexopathy in patients with nasopharyngeal carcinoma: a retrospective study

https://doi.org/10.18632/oncotarget.7748

Zhaoxi Cai, Yi Li, Zhen Hu, Ruying Fu, Xiaoming Rong, Rong Wu, Jinping Cheng, Xiaolong Huang, Jinjun Luo,  and Yamei Tang
18887-18895
Abstract  |  PDF  |  HTML  |  Order a Reprint

Exogenous p53 and ASPP2 expression enhances rAdV-TK/ GCV-induced death in hepatocellular carcinoma cells lacking functional p53

Exogenous p53 and ASPP2 expression enhances rAdV-TK/ GCV-induced death in hepatocellular carcinoma cells lacking functional p53

https://doi.org/10.18632/oncotarget.7749

Xiuhong Liu, Shuang Wang, Xianghua Guo, Feili Wei, Jiming Yin, Yunjin Zang, Ning Li,  and Dexi Chen
18896-18905
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

MiR-449a promotes breast cancer progression by targeting CRIP2

MiR-449a promotes breast cancer progression by targeting CRIP2

https://doi.org/10.18632/oncotarget.7753

Wei Shi, Jeff Bruce, Matthew Lee, Shijun Yue, Matthew Rowe, Melania Pintilie, Ryunosuke Kogo, Pierre-Antoine Bissey, Anthony Fyles, Kenneth W. Yip,  and Fei-Fei Liu
18906-18918
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Smoking-promoted oxidative DNA damage response is highly correlated to lung carcinogenesis

Smoking-promoted oxidative DNA damage response is highly correlated to lung carcinogenesis

https://doi.org/10.18632/oncotarget.7810

Chao Cao, Tianwen Lai, Miao Li, Hongbin Zhou, Dan Lv, Zaichun Deng, Songmin Ying, Zhihua Chen, Wen Li,  and Huahao Shen
18919-18926
Abstract  |  PDF  |  HTML  |  Order a Reprint

SIRT2 inhibits non-small cell lung cancer cell growth through impairing Skp2-mediated p27 degradation

SIRT2 inhibits non-small cell lung cancer cell growth through impairing Skp2-mediated p27 degradation

https://doi.org/10.18632/oncotarget.7816

Ziming Li, Jia Huang, Hong Yuan, Zhiwei Chen, Qingquan Luo,  and Shun Lu
18927-18939
Abstract  |  PDF  |  HTML  |  Order a Reprint

PTBP1-associated microRNA-1 and -133b suppress the Warburg effect in colorectal tumors

PTBP1-associated microRNA-1 and -133b suppress the Warburg effect in colorectal tumors

https://doi.org/10.18632/oncotarget.8005

Kohei Taniguchi, Miku Sakai, Nobuhiko Sugito, Minami Kumazaki, Haruka Shinohara, Nami Yamada, Tatsushi Nakayama, Hiroshi Ueda, Yoshihito Nakagawa, Yuko Ito, Manabu Futamura, Bunji Uno, Yoshinori Otsuki, Kazuhiro Yoshida, Kazuhisa Uchiyama,  and Yukihiro Akao
18940-18952
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Genomic markers of panitumumab resistance including ERBB2/ HER2 in a phase II study of KRAS wild-type (wt) metastatic colorectal cancer (mCRC)

Genomic markers of panitumumab resistance including ERBB2/ HER2 in a phase II study of KRAS wild-type (wt) metastatic colorectal cancer (mCRC)

https://doi.org/10.18632/oncotarget.8006

Garrett S. Barry, Maggie C. Cheang, Hector Li Chang,  and Hagen F. Kennecke
18953-18964
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Metformin combined with sodium dichloroacetate promotes B leukemic cell death by suppressing anti-apoptotic protein Mcl-1

Metformin combined with sodium dichloroacetate promotes B leukemic cell death by suppressing anti-apoptotic protein Mcl-1

https://doi.org/10.18632/oncotarget.7879

Rebecca Voltan, Erika Rimondi, Elisabetta Melloni, Paola Gilli, Valerio Bertolasi, Fabio Casciano, Gian Matteo Rigolin, Giorgio Zauli,  and Paola Secchiero
18965-18977
Abstract  |  PDF  |  HTML  |  Order a Reprint

A wait-and-watch approach to small pancreatic neuroendocrine tumors: prognosis and survival

A wait-and-watch approach to small pancreatic neuroendocrine tumors: prognosis and survival

https://doi.org/10.18632/oncotarget.7902

Sara Massironi, Roberta Elisa Rossi, Alessandra Zilli, Giovanni Casazza, Clorinda Ciafardini,  and Dario Conte
18978-18983
Abstract  |  PDF  |  HTML  |  Order a Reprint

A single-nucleotide polymorphism in the 3′-UTR region of the adipocyte fatty acid binding protein 4 gene is associated with prognosis of triple-negative breast cancer

A single-nucleotide polymorphism in the 3′-UTR region of the adipocyte fatty acid binding protein 4 gene is associated with prognosis of triple-negative breast cancer

https://doi.org/10.18632/oncotarget.7920

Wenmiao Wang, Peng Yuan, Dianke Yu, Feng Du, Anjie Zhu, Qing Li, Pin Zhang, Dongxin Lin,  and Binghe Xu
18984-18998
Abstract  |  PDF  |  HTML  |  Order a Reprint

EBV reactivation as a target of luteolin to repress NPC tumorigenesis

EBV reactivation as a target of luteolin to repress NPC tumorigenesis

https://doi.org/10.18632/oncotarget.7967

Chung-Chun Wu, Chih-Yeu Fang, Hui-Yu Hsu, Hsin-Ying Chuang, Yu-Jhen Cheng, Yen-Ju Chen, Sheng-Ping Chou, Sheng-Yen Huang, Su-Fang Lin, Yao Chang, Ching-Hwa Tsai,  and Jen-Yang Chen
18999-19017
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

ZLM-7 exhibits anti-angiogenic effects via impaired endothelial cell function and blockade of VEGF/VEGFR-2 signaling

ZLM-7 exhibits anti-angiogenic effects via impaired endothelial cell function and blockade of VEGF/VEGFR-2 signaling

https://doi.org/10.18632/oncotarget.7968

Min Su, Jingjia Huang, Jijia Li, Xiyuan Qin, Xiaoning Tang, Fang Jin, Shali Chen, Chuanming Jiang, Zizheng Zou, Kunjian Peng, Mohammed Nuruzzaman, Jianting Zhang, Junli Luo, Suyou Liu,  and Zhiyong Luo
19018-19030
Abstract  |  PDF  |  HTML  |  Order a Reprint

Instigation of NLRP3 inflammasome activation and glomerular injury in mice on the high fat diet: role of acid sphingomyelinase gene

Instigation of NLRP3 inflammasome activation and glomerular injury in mice on the high fat diet: role of acid sphingomyelinase gene

https://doi.org/10.18632/oncotarget.8023

Krishna M. Boini, Min Xia, Saisudha Koka, Todd w. Gehr,  and Pin-Lan Li
19031-19044
Abstract  |  PDF  |  HTML  |  Order a Reprint

Clinical Research Papers

Comparing the clinical outcomes in stereotactic body radiotherapy for lung tumors between Ray-Tracing and Monte-Carlo algorithms

Comparing the clinical outcomes in stereotactic body radiotherapy for lung tumors between Ray-Tracing and Monte-Carlo algorithms

https://doi.org/10.18632/oncotarget.5992

Jin Ho Song, Ki Mun Kang, Hoon-Sik Choi, Hojin Jeong, In Bong Ha, Jong Deog Lee, Ho Cheol Kim, Yi Yeong Jeong, Yu Ji Cho, Seung Jun Lee, Sung Hwan Kim, In-Seok Jang,  and Bae Kwon Jeong
19045-19053
Abstract  |  PDF  |  HTML  |  Order a Reprint

Associations between polymorphisms of long non-coding RNA MEG3 and risk of colorectal cancer in Chinese

Associations between polymorphisms of long non-coding RNA MEG3 and risk of colorectal cancer in Chinese

https://doi.org/10.18632/oncotarget.7764

Xiangming Cao, Shulin Zhuang, Youfang Hu, Lei Xi, Lichun Deng, Huaming Sheng,  and Weisheng Shen
19054-19059
Abstract  |  PDF  |  HTML  |  Order a Reprint

A rank-based transcriptional signature for predicting relapse risk of stage II colorectal cancer identified with proper data sources

A rank-based transcriptional signature for predicting relapse risk of stage II colorectal cancer identified with proper data sources

https://doi.org/10.18632/oncotarget.7956

Wenyuan Zhao, Beibei Chen, Xin Guo, Ruiping Wang, Zhiqiang Chang, Yu Dong, Kai Song, Wen Wang, Lishuang Qi, Yunyan Gu, Chenguang Wang, Da Yang,  and Zheng Guo
19060-19071
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Prognostic significance of bone marrow infiltration detected by PET-CT in newly diagnosed diffuse large B cell lymphoma

Prognostic significance of bone marrow infiltration detected by PET-CT in newly diagnosed diffuse large B cell lymphoma

https://doi.org/10.18632/oncotarget.7616

Jin-Hua Liang, Jin Sun, Li Wang, Lei Fan, Yao-Yu Chen, Xiao-Yan Qu, Tian-Nv Li, Jian-Yong Li,  and Wei Xu
19072-19080
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Survival following segmentectomy or lobectomy in elderly patients with early-stage lung cancer

Survival following segmentectomy or lobectomy in elderly patients with early-stage lung cancer

https://doi.org/10.18632/oncotarget.7704

Yang Zhang, Chongze Yuan, Yawei Zhang, Yihua Sun,  and Haiquan Chen
19081-19086
Abstract  |  PDF  |  HTML  |  Order a Reprint


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