Oncotarget

Vol 7, No 13

March 29, 2016

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About The Cover

Sixth BHD symposium and first international upstate kidney cancer symposium: latest scientific and clinical discoveries. See Bratslavsky et al.

Table of Contents

Editorial

Synapsin III in brain development

Synapsin III in brain development

https://doi.org/10.18632/oncotarget.8106

Laura E. Perlini, Fabio Benfenati,  and Laura Cancedda
15288-15289
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Editorial: Gerotarget (Focus on Aging)

TGF-β1-Smad signaling pathways are not required for epidermal LC homeostasis

TGF-β1-Smad signaling pathways are not required for epidermal LC homeostasis

https://doi.org/10.18632/oncotarget.8167

Guihua Li, Xing-hua Gao,  and Qing-Sheng Mi
15290-15291
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Meeting Reports

Sixth BHD Symposium and First International Upstate Kidney Cancer Symposium: latest scientific and clinical discoveries

Sixth BHD Symposium and First International Upstate Kidney Cancer Symposium: latest scientific and clinical discoveries

https://doi.org/10.18632/oncotarget.7733

Gennady Bratslavsky, Mark R. Woodford, Michael Daneshvar,  and Mehdi Mollapour
15292-15298
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Priority Research Papers

Divergent branches of mitochondrial signaling regulate specific genes and the viability of specialized cell types of differentiated yeast colonies

Divergent branches of mitochondrial signaling regulate specific genes and the viability of specialized cell types of differentiated yeast colonies

https://doi.org/10.18632/oncotarget.8084

Kristýna Podholová, Vítězslav Plocek, Stanislava Rešetárová, Helena Kučerová, Otakar Hlaváček, Libuše Váchová,  and Zdena Palková
15299-15314
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Research Papers: Gerotarget (Focus on Aging)

Multiple genetic imaging study of the association between cholesterol metabolism and brain functional alterations in individuals with risk factors for Alzheimer’s disease

Multiple genetic imaging study of the association between cholesterol metabolism and brain functional alterations in individuals with risk factors for Alzheimer’s disease

https://doi.org/10.18632/oncotarget.8100

Feng Bai, Yonggui Yuan, Yongmei Shi,  and Zhijun Zhang
15315-15328
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Research Papers: Pathology

Altered expression of neuropeptide Y receptors caused by focal cortical dysplasia in human intractable epilepsy

Altered expression of neuropeptide Y receptors caused by focal cortical dysplasia in human intractable epilepsy

https://doi.org/10.18632/oncotarget.7855

Lin Li, Jiahui Deng, Changqing Liu, Hanjiang Luo, Yuguang Guan, Jian Zhou, Xueling Qi, Tianfu Li, Zhiqing David Xu,  and Guo-Ming Luan
15329-15338
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Deinococcus radiodurans pprI expression enhances the radioresistance of eukaryotes

Deinococcus radiodurans pprI expression enhances the radioresistance of eukaryotes

https://doi.org/10.18632/oncotarget.8137

Ling Wen, Ling Yue, Yi Shi, Lili Ren, Tingting Chen, Na Li, Shuyu Zhang, Wei Yang,  and Zhanshan Yang
15339-15355
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Research Papers: Immunology

Exosomes released by granulocytic myeloid-derived suppressor cells attenuate DSS-induced colitis in mice

Exosomes released by granulocytic myeloid-derived suppressor cells attenuate DSS-induced colitis in mice

https://doi.org/10.18632/oncotarget.7324

Yungang Wang, Jie Tian, Xinyi Tang, Ke Rui, Xinyu Tian, Jie Ma, Bin Ma, Huaxi Xu, Liwei Lu,  and Shengjun Wang
15356-15368
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Downregulation of the stress-induced ligand ULBP1 following SV40 infection confers viral evasion from NK cell cytotoxicity

Downregulation of the stress-induced ligand ULBP1 following SV40 infection confers viral evasion from NK cell cytotoxicity

https://doi.org/10.18632/oncotarget.8085

Yoav Bauman, Nir Drayman, Orly Ben-Nun-Shaul, Alon Vitenstein, Rachel Yamin, Yael Ophir, Ariella Oppenheim,  and Ofer Mandelboim
15369-15381
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CCR5 knockout suppresses experimental autoimmune encephalomyelitis in C57BL/6 mice

CCR5 knockout suppresses experimental autoimmune encephalomyelitis in C57BL/6 mice

https://doi.org/10.18632/oncotarget.8097

Sun Mi Gu, Mi Hee Park, Hyung Mun Yun, Sang Bae Han, Ki Wan Oh, Dong Ju Son, Jae Suk Yun,  and Jin Tae Hong
15382-15393
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Protein phosphatase, Mg2+/Mn2+-dependent 1A controls the innate antiviral and antibacterial response of macrophages during HIV-1 and Mycobacterium tuberculosis infection

Protein phosphatase, Mg2+/Mn2+-dependent 1A controls the innate antiviral and antibacterial response of macrophages during HIV-1 and Mycobacterium tuberculosis infection

https://doi.org/10.18632/oncotarget.8190

Jim Sun, Kaitlyn Schaaf, Alexandra Duverger, Frank Wolschendorf, Alexander Speer, Frederic Wagner, Michael Niederweis,  and Olaf Kutsch
15394-15409
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Reviews: Gerotarget (Focus on Aging)

Reprogramming of energy metabolism as a driver of aging

Reprogramming of energy metabolism as a driver of aging

https://doi.org/10.18632/oncotarget.7645

Zhaoyang Feng, Richard W. Hanson, Nathan A. Berger,  and Alexander Trubitsyn
15410-15420
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Reviews: Immunology

Improving the clinical impact of biomaterials in cancer immunotherapy

Improving the clinical impact of biomaterials in cancer immunotherapy

https://doi.org/10.18632/oncotarget.7304

Joshua M. Gammon, Neil M. Dold,  and Christopher M. Jewell
15421-15443
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Reviews

Tumor resistance to vascular disrupting agents: mechanisms, imaging, and solutions

Tumor resistance to vascular disrupting agents: mechanisms, imaging, and solutions

https://doi.org/10.18632/oncotarget.6999

Wenjie Liang, Yicheng Ni,  and Feng Chen
15444-15459
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Potential therapeutic implications of IL-6/IL-6R/gp130-targeting agents in breast cancer

Potential therapeutic implications of IL-6/IL-6R/gp130-targeting agents in breast cancer

https://doi.org/10.18632/oncotarget.7102

Tae-Hwe Heo, Joseph Wahler,  and Nanjoo Suh
15460-15473
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Research Papers

Survival benefit of radiotherapy to patients with small cell esophagus carcinoma - an analysis of Surveillance Epidemiology and End Results (SEER) data

Survival benefit of radiotherapy to patients with small cell esophagus carcinoma - an analysis of Surveillance Epidemiology and End Results (SEER) data

https://doi.org/10.18632/oncotarget.6764

Yaqi Song, Wanwei Wang, Guangzhou Tao, Weiguo Zhu, Xilei Zhou,  and Peng Pan
15474-15480
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Regulation of androgen receptor splice variant AR3 by PCGEM1

Regulation of androgen receptor splice variant AR3 by PCGEM1

https://doi.org/10.18632/oncotarget.7139

Ziqiang Zhang, Nanjiang Zhou, Jianguo Huang, Tsui-Ting Ho, Zhuxian Zhu, Zhongmin Qiu, Xinchun Zhou, Chunxue Bai, Fangting Wu, Min Xu,  and Yin-Yuan Mo
15481-15491
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Integrated experimental and simulation study of the response to sequential treatment with erlotinib and gemcitabine in pancreatic cancer

Integrated experimental and simulation study of the response to sequential treatment with erlotinib and gemcitabine in pancreatic cancer

https://doi.org/10.18632/oncotarget.7491

Paolo Ubezio, Francesca Falcetta, Laura Carrassa,  and Monica Lupi
15492-15506
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Isolation and characterization of renal cancer stem cells from patient-derived xenografts

Isolation and characterization of renal cancer stem cells from patient-derived xenografts

https://doi.org/10.18632/oncotarget.6266

Meriem Hasmim, Stefania Bruno, Sandy Azzi, Cindy Gallerne, Julien Giron Michel, Giulia Chiabotto, Vincent Lecoz, Cristina Romei, Grazia Maria Spaggiari, Annalisa Pezzolo, Vito Pistoia, Eric Angevin, Sophie Gad, Sophie Ferlicot, Yosra Messai, Claudine Kieda, Denis Clay, Federica Sabatini, Bernard Escudier, Giovanni Camussi, Pierre Eid, Bruno Azzarone,  and Salem Chouaib
15507-15524
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CD68 and interleukin 13, prospective immune markers for esophageal squamous cell carcinoma prognosis prediction

CD68 and interleukin 13, prospective immune markers for esophageal squamous cell carcinoma prognosis prediction

https://doi.org/10.18632/oncotarget.6900

Jian Li, Bao-Zhu Zhang, Yan-Ru Qin, Jiong Bi, Hai-Bo Liu, Yan Li, Mu-Yan Cai, Stephanie Ma, Kwok Wah Chan, Dan Xie,  and Xin-Yuan Guan
15525-15538
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A novel intracellular antibody against the E6 oncoprotein impairs growth of human papillomavirus 16-positive tumor cells in mouse models

A novel intracellular antibody against the E6 oncoprotein impairs growth of human papillomavirus 16-positive tumor cells in mouse models

https://doi.org/10.18632/oncotarget.6925

Carla Amici, Michela Visintin, Francesca Verachi, Francesca Paolini, Zulema Percario, Paola Di Bonito, Angela Mandarino, Elisabetta Affabris, Aldo Venuti,  and Luisa Accardi
15539-15553
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Protective effect of α-lipoic acid against radiation-induced fibrosis in mice

Protective effect of α-lipoic acid against radiation-induced fibrosis in mice

https://doi.org/10.18632/oncotarget.6952

Seung-Hee Ryu, Eun-Young Park, Sungmin Kwak, Seung-Ho Heo, Je-Won Ryu, Jin-hong Park, Kyung-Chul Choi,  and Sang-wook Lee
15554-15565
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The prognostic value of pretreatment CA-125 levels and CA-125 normalization in ovarian clear cell carcinoma: a two-academic-institute study

The prognostic value of pretreatment CA-125 levels and CA-125 normalization in ovarian clear cell carcinoma: a two-academic-institute study

https://doi.org/10.18632/oncotarget.7216

Huimin Bai, Guisha Sha, Meizhu Xiao, Huiqiao Gao, Dongyan Cao, Jiaxin Yang, Jie Chen, Yue Wang, Zhenyu Zhang,  and Keng Shen
15566-15576
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Implications of a peroxisome proliferator-activated receptor alpha (PPARα) ligand clofibrate in breast cancer

Implications of a peroxisome proliferator-activated receptor alpha (PPARα) ligand clofibrate in breast cancer

https://doi.org/10.18632/oncotarget.6402

Karthic Chandran, Sudeshna Goswami,  and Neelam Sharma-Walia
15577-15599
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Meta-analysis of the association between selenium and gastric cancer risk

Meta-analysis of the association between selenium and gastric cancer risk

https://doi.org/10.18632/oncotarget.7205

He-Yi Gong, Jin-Guang He,  and Bao-Sheng Li
15600-15605
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Sialylated immunoglobulin G can neutralize influenza virus infection through receptor mimicry

Sialylated immunoglobulin G can neutralize influenza virus infection through receptor mimicry

https://doi.org/10.18632/oncotarget.7244

Tao Huang, Xueling Chen, Conghui Zhao, Xingmu Liu, Zaiping Zhang, Tongfei Li, Ruiman Sun, Huan Gu,  and Jiang Gu
15606-15617
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Allele-specific recognition by LILRB3 and LILRA6 of a cytokeratin 8 - associated ligand on necrotic glandular epithelial cells

Allele-specific recognition by LILRB3 and LILRA6 of a cytokeratin 8 - associated ligand on necrotic glandular epithelial cells

https://doi.org/10.18632/oncotarget.6905

Des C. Jones, Colin R.A. Hewitt, María R. López-Álvarez, Martin Jahnke, Alasdair I. Russell, Valeria Radjabova, Alice R.Z. Trowsdale,  and John Trowsdale
15618-15631
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CCL2-CCR2 axis promotes metastasis of nasopharyngeal carcinoma by activating ERK1/2-MMP2/9 pathway

CCL2-CCR2 axis promotes metastasis of nasopharyngeal carcinoma by activating ERK1/2-MMP2/9 pathway

https://doi.org/10.18632/oncotarget.6695

Jing Yang, Xing Lv, Jinna Chen, Changqing Xie, Weixiong Xia, Chen Jiang, Tingting Zeng, Yanfang Ye, Liangru Ke, Yahui Yu, Hu Liang, Xin-Yuan Guan, Xiang Guo,  and Yanqun Xiang
15632-15647
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Integrated transcriptomic and proteomic analysis identifies protein kinase CK2 as a key signaling node in an inflammatory cytokine network in ovarian cancer cells

Integrated transcriptomic and proteomic analysis identifies protein kinase CK2 as a key signaling node in an inflammatory cytokine network in ovarian cancer cells

https://doi.org/10.18632/oncotarget.7255

Hagen Kulbe, Francesco Iorio, Probir Chakravarty, Carla S. Milagre, Robert Moore, Richard G. Thompson, Gemma Everitt, Monica Canosa, Alexander Montoya, Denis Drygin, Ioana Braicu, Jalid Sehouli, Julio Saez-Rodriguez, Pedro R. Cutillas,  and Frances R. Balkwill
15648-15661
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Barrier-to-Autointegration Factor (BAF) involvement in prelamin A-related chromatin organization changes

Barrier-to-Autointegration Factor (BAF) involvement in prelamin A-related chromatin organization changes

https://doi.org/10.18632/oncotarget.6697

Manuela Loi, Vittoria Cenni, Serena Duchi, Stefano Squarzoni, Carlos Lopez- Otin, Roland Foisner, Giovanna Lattanzi,  and Cristina Capanni
15662-15677
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Repulsive guidance molecule B inhibits metastasis and is associated with decreased mortality in non-small cell lung cancer

Repulsive guidance molecule B inhibits metastasis and is associated with decreased mortality in non-small cell lung cancer

https://doi.org/10.18632/oncotarget.7463

Jin Li, Lin Ye, Xiaoshun Shi, Jingyi Chen, Fenglan Feng, Yaoqi Chen, Yiren Xiao, Jianfei Shen, Peng Li, Wen G. Jiang,  and Jianxing He
15678-15689
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

IMP1 suppresses breast tumor growth and metastasis through the regulation of its target mRNAs

IMP1 suppresses breast tumor growth and metastasis through the regulation of its target mRNAs

https://doi.org/10.18632/oncotarget.7464

Guangli Wang, Zhenqiang Huang, Xin Liu, Wenhe Huang, Shaoying Chen, Yanchun Zhou, Deling Li, Robert H. Singer,  and Wei Gu
15690-15702
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The E1B19K-deleted oncolytic adenovirus mutant AdΔ19K sensitizes pancreatic cancer cells to drug-induced DNA-damage by down-regulating Claspin and Mre11

The E1B19K-deleted oncolytic adenovirus mutant AdΔ19K sensitizes pancreatic cancer cells to drug-induced DNA-damage by down-regulating Claspin and Mre11

https://doi.org/10.18632/oncotarget.7310

Constantia Pantelidou, Gioia Cherubini, Nick R. Lemoine,  and Gunnel Halldén
15703-15724
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Gamabufotalin triggers c-Myc degradation via induction of WWP2 in multiple myeloma cells

Gamabufotalin triggers c-Myc degradation via induction of WWP2 in multiple myeloma cells

https://doi.org/10.18632/oncotarget.7398

Zhenlong Yu, Tao Li, Chao Wang, Sa Deng, Baojing Zhang, Xiaokui Huo, Bo Zhang, Xiaobo Wang, Yuping Zhong,  and Xiaochi Ma
15725-15737
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Ubiquitin ligase UBE3C promotes melanoma progression by increasing epithelial-mesenchymal transition in melanoma cells

Ubiquitin ligase UBE3C promotes melanoma progression by increasing epithelial-mesenchymal transition in melanoma cells

https://doi.org/10.18632/oncotarget.7393

Li Tang, Xue-Mei Yi, Jia Chen, Fu-Juan Chen, Wei Lou, Yun-Lu Gao, Jing Zhou, Li-Na Su, Xin Xu, Jia-Qing Lu, Jun Ma, Ning Yu,  and Yang-Feng Ding
15738-15746
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Bladder cancer cells secrete while normal bladder cells express but do not secrete AGR2

Bladder cancer cells secrete while normal bladder cells express but do not secrete AGR2

https://doi.org/10.18632/oncotarget.7400

Melissa E. Ho, Sue-Ing Quek, Lawrence D. True, Roland Seiler, Achim Fleischmann, Lora Bagryanova, Sara R. Kim, David Chia, Lee Goodglick, Yoshiko Shimizu, Charles J. Rosser, Yuqian Gao,  and Alvin Y. Liu
15747-15756
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Genome-wide functional genetic screen with the anticancer agent AMPI-109 identifies PRL-3 as an oncogenic driver in triple-negative breast cancers

Genome-wide functional genetic screen with the anticancer agent AMPI-109 identifies PRL-3 as an oncogenic driver in triple-negative breast cancers

https://doi.org/10.18632/oncotarget.7462

Hamid H. Gari, Christy M. Gearheart, Susan Fosmire, Gregory D. DeGala, Zeying Fan, Kathleen C. Torkko, Susan M. Edgerton, M. Scott Lucia, Rahul Ray, Ann D. Thor, Christopher C. Porter,  and James R. Lambert
15757-15771
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Pre-neoplastic epigenetic disruption of transcriptional enhancers in chronic inflammation

Pre-neoplastic epigenetic disruption of transcriptional enhancers in chronic inflammation

https://doi.org/10.18632/oncotarget.7513

Aline C. Planello, Rajat Singhania, Ken J. Kron, Swneke D. Bailey, David Roulois, Mathieu Lupien, Sérgio R. Peres Line, Ana Paula de Souza,  and Daniel D. De Carvalho
15772-15786
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

LncRNA MT1JP functions as a tumor suppressor by interacting with TIAR to modulate the p53 pathway

LncRNA MT1JP functions as a tumor suppressor by interacting with TIAR to modulate the p53 pathway

https://doi.org/10.18632/oncotarget.7487

Lihui Liu, Haiyan Yue, Qinghua Liu, Jiao Yuan, Jing Li, Guifeng Wei, Xiaomin Chen, Youyong Lu, Mingzhou Guo, Jianjun Luo,  and Runsheng Chen
15787-15800
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Comparative efficacy and safety of first-line treatments in patients with metastatic renal cell cancer: a network meta-analysis based on phase 3 RCTs

Comparative efficacy and safety of first-line treatments in patients with metastatic renal cell cancer: a network meta-analysis based on phase 3 RCTs

https://doi.org/10.18632/oncotarget.7511

Xiaofeng Chang, Fan Zhang, Tieshi Liu, Rong Yang, Changwei Ji, Xiaozhi Zhao, Linfeng Xu, Guangxiang Liu,  and Hongqian Guo
15801-15810
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ADP-ribosylation factor 1 expression regulates epithelial-mesenchymal transition and predicts poor clinical outcome in triple-negative breast cancer

ADP-ribosylation factor 1 expression regulates epithelial-mesenchymal transition and predicts poor clinical outcome in triple-negative breast cancer

https://doi.org/10.18632/oncotarget.7515

Sabrina Schlienger, Shirley Campbell, Sarah Pasquin, Louis Gaboury,  and Audrey Claing
15811-15827
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

High expression of RUNX1 is associated with poorer outcomes in cytogenetically normal acute myeloid leukemia

High expression of RUNX1 is associated with poorer outcomes in cytogenetically normal acute myeloid leukemia

https://doi.org/10.18632/oncotarget.7489

Lin Fu, Huaping Fu, Lei Tian, Keman Xu, Kai Hu, Jing Wang, Jijun Wang, Hongmei Jing, Jinlong Shi,  and Xiaoyan Ke
15828-15839
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

miR-486-5p expression pattern in esophageal squamous cell carcinoma, gastric cancer and its prognostic value

miR-486-5p expression pattern in esophageal squamous cell carcinoma, gastric cancer and its prognostic value

https://doi.org/10.18632/oncotarget.7417

Chuanli Ren, Hui Chen, Chongxu Han, Deyuan Fu, Lin Zhou, Guangfu Jin, Fuan Wang, Daxin Wang, Yong Chen, Li Ma, Xucai Zheng,  and Dongsheng Han
15840-15853
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14-3-3ζ promotes hepatocellular carcinoma venous metastasis by modulating hypoxia-inducible factor-1α

14-3-3ζ promotes hepatocellular carcinoma venous metastasis by modulating hypoxia-inducible factor-1α

https://doi.org/10.18632/oncotarget.7493

Yufu Tang, Shupeng Liu, Nan Li, Weixing Guo, Jie Shi, Hongming Yu, Long Zhang, Kang Wang, Shangrong Liu,  and Shuqun Cheng
15854-15867
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SI113, a SGK1 inhibitor, potentiates the effects of radiotherapy, modulates the response to oxidative stress and induces cytotoxic autophagy in human glioblastoma multiforme cells

SI113, a SGK1 inhibitor, potentiates the effects of radiotherapy, modulates the response to oxidative stress and induces cytotoxic autophagy in human glioblastoma multiforme cells

https://doi.org/10.18632/oncotarget.7520

Cristina Talarico, Vincenzo Dattilo, Lucia D’Antona, Agnese Barone, Nicola Amodio, Stefania Belviso, Francesca Musumeci, Claudia Abbruzzese, Cataldo Bianco, Francesco Trapasso, Silvia Schenone, Stefano Alcaro, Francesco Ortuso, Tullio Florio, Marco G. Paggi, Nicola Perrotti,  and Rosario Amato
15868-15884
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Pathway of PPAR-gamma coactivators in thermogenesis: a pivotal traditional Chinese medicine-associated target for individualized treatment of rheumatoid arthritis

Pathway of PPAR-gamma coactivators in thermogenesis: a pivotal traditional Chinese medicine-associated target for individualized treatment of rheumatoid arthritis

https://doi.org/10.18632/oncotarget.7419

Yanqiong Zhang, Xia Mao, Qiuyan Guo, Ming Bai, Bo Zhang, Chunfang Liu, Yanqun Sun, Shao Li,  and Na Lin
15885-15900
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

PD-L1 expression is associated with epithelial-mesenchymal transition in head and neck squamous cell carcinoma

PD-L1 expression is associated with epithelial-mesenchymal transition in head and neck squamous cell carcinoma

https://doi.org/10.18632/oncotarget.7431

Chan-Young Ock, Sehui Kim, Bhumsuk Keam, Miso Kim, Tae Min Kim, Jin-Ho Kim, Yoon Kyung Jeon, Ju-Seog Lee, Seong Keun Kwon, Hun J. Hah, Tack-Kyun Kwon, Dong-Wan Kim, Hong-Gyun Wu, Myung-Whun Sung,  and Dae Seog Heo
15901-15914
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

miR-30e controls DNA damage-induced stress responses by modulating expression of the CDK inhibitor p21WAF1/CIP1 and caspase-3

miR-30e controls DNA damage-induced stress responses by modulating expression of the CDK inhibitor p21WAF1/CIP1 and caspase-3

https://doi.org/10.18632/oncotarget.7432

Dennis Sohn, Dominik Peters, Roland P. Piekorz, Wilfried Budach,  and Reiner U. Jänicke
15915-15929
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Genetic variant rs4072037 of MUC1 and gastric cancer risk in an Eastern Chinese population

Genetic variant rs4072037 of MUC1 and gastric cancer risk in an Eastern Chinese population

https://doi.org/10.18632/oncotarget.7527

Li-Xin Qiu, Rui-Xi Hua, Lei Cheng, Jing He, Meng-Yun Wang, Fei Zhou, Xiao-Dong Zhu, Meng-Hong Sun, Xiao-Yan Zhou, Jin Li, Ya-Nong Wang, Ya-Jun Yang, Jiu-Cun Wang, Li Jin, Wei-Jian Guo,  and Qing-Yi Wei
15930-15936
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Prognostic significance and optimal cutoff of age in medullary thyroid cancer

Prognostic significance and optimal cutoff of age in medullary thyroid cancer

https://doi.org/10.18632/oncotarget.7556

Ning Qu, Rong-liang Shi, Ting-xian Luo, Yu-long Wang, Duan-shu Li, Yu Wang, Cai-ping Huang,  and Qing-hai Ji
15937-15947
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A genetic variation in microRNA target site of ETS2 is associated with clinical outcomes of paclitaxel-cisplatin chemotherapy in non-small cell lung cancer

A genetic variation in microRNA target site of ETS2 is associated with clinical outcomes of paclitaxel-cisplatin chemotherapy in non-small cell lung cancer

https://doi.org/10.18632/oncotarget.7433

Mi Jeong Hong, Shin Yup Lee, Jin Eun Choi, Cheng Cheng Jin, Hyo Jung Kang, Sun Ah Baek, So Yeon Lee, Kyung Min Shin, Ji Yun Jeong, Won Kee Lee, Seung Soo Yoo, Jaehee Lee, Seung Ick Cha, Chang Ho Kim, Ji Woong Son,  and Jae Yong Park
15948-15958
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Efficacy of targeted AKT inhibition in genetically engineered mouse models of PTEN-deficient prostate cancer

Efficacy of targeted AKT inhibition in genetically engineered mouse models of PTEN-deficient prostate cancer

https://doi.org/10.18632/oncotarget.7557

Marco A. De Velasco, Yurie Kura, Kazuhiro Yoshikawa, Kazuto Nishio, Barry R. Davies,  and Hirotsugu Uemura
15959-15976
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Role of microRNAs in epigenetic silencing of the CHD5 tumor suppressor gene in neuroblastomas

Role of microRNAs in epigenetic silencing of the CHD5 tumor suppressor gene in neuroblastomas

https://doi.org/10.18632/oncotarget.7434

Koumudi Naraparaju, Venkatadri Kolla, Tiangang Zhuang, Mayumi Higashi, Radhika Iyer, Sriharsha Kolla, Erin R. Okawa, Gerd A. Blobel,  and Garrett M. Brodeur
15977-15985
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Inhibition of MARCH5 ubiquitin ligase abrogates MCL1-dependent resistance to BH3 mimetics via NOXA

Inhibition of MARCH5 ubiquitin ligase abrogates MCL1-dependent resistance to BH3 mimetics via NOXA

https://doi.org/10.18632/oncotarget.7558

Aishwarya Subramanian, Adrian Andronache, Yao-Cheng Li,  and Mark Wade
15986-16002
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

ZEB2 inhibits HBV transcription and replication by targeting its core promoter

ZEB2 inhibits HBV transcription and replication by targeting its core promoter

https://doi.org/10.18632/oncotarget.7435

Qiao He, Wanyu Li, Jihua Ren, Yecai Huang, Ying Huang, Qin Hu, Juan Chen,  and Weixian Chen
16003-16011
Abstract  |  PDF  |  HTML  |  Order a Reprint

Comprehensive analysis of lncRNA expression profiles and identification of functional lncRNAs in lung adenocarcinoma

Comprehensive analysis of lncRNA expression profiles and identification of functional lncRNAs in lung adenocarcinoma

https://doi.org/10.18632/oncotarget.7559

Mantang Qiu, Dongjie Feng, Haitian Zhang, Wenjia Xia, Youtao Xu, Jie Wang, Gaochao Dong, Yewei Zhang, Rong Yin,  and Lin Xu
16012-16022
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Novel role of STRAP in progression and metastasis of colorectal cancer through Wnt/β-catenin signaling

Novel role of STRAP in progression and metastasis of colorectal cancer through Wnt/β-catenin signaling

https://doi.org/10.18632/oncotarget.7532

Guandou Yuan, Bixiang Zhang, Shanzhong Yang, Lin Jin, Arunima Datta, Sejong Bae, Xiaoping Chen,  and Pran K Datta
16023-16037
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Increased expression of SUMO1P3 predicts poor prognosis and promotes tumor growth and metastasis in bladder cancer

Increased expression of SUMO1P3 predicts poor prognosis and promotes tumor growth and metastasis in bladder cancer

https://doi.org/10.18632/oncotarget.6946

Yonghao Zhan, Yuchen Liu, Chaoliang Wang, Junhao Lin, Mingwei Chen, Xiaoying Chen, Chengle Zhuang, Li Liu, Wen Xu, Qing Zhou, Xiaojuan Sun, Qiaoxia Zhang, Guoping Zhao,  and Weiren Huang
16038-16048
Abstract  |  PDF  |  HTML  |  Order a Reprint

Estrogen receptor alpha (ERα/ESR1) mediates the p53-independent overexpression of MDM4/MDMX and MDM2 in human breast cancer

Estrogen receptor alpha (ERα/ESR1) mediates the p53-independent overexpression of MDM4/MDMX and MDM2 in human breast cancer

https://doi.org/10.18632/oncotarget.7533

Wendy M. Swetzig, Jianmin Wang,  and Gokul M. Das
16049-16069
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Podoplanin is a component of extracellular vesicles that reprograms cell-derived exosomal proteins and modulates lymphatic vessel formation

Podoplanin is a component of extracellular vesicles that reprograms cell-derived exosomal proteins and modulates lymphatic vessel formation

https://doi.org/10.18632/oncotarget.7445

Patricia Carrasco-Ramírez, David W. Greening, Germán Andrés, Shashi K. Gopal, Ester Martín-Villar, Jaime Renart, Richard J. Simpson,  and Miguel Quintanilla
16070-16089
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Involvement of SULF2 in 𝛄-irradiation-induced invasion and resistance of cancer cells by inducing IL-6 expression

Involvement of SULF2 in 𝛄-irradiation-induced invasion and resistance of cancer cells by inducing IL-6 expression

https://doi.org/10.18632/oncotarget.7449

Chan-Hun Jung, Jin-Nyoung Ho, Jong Kuk Park, Eun Mi Kim, Sang-Gu Hwang,  and Hong-Duck Um
16090-16103
Abstract  |  PDF  |  HTML  |  Order a Reprint

Genetic association study identifies a functional CNV in the WWOX gene contributes to the risk of intracranial aneurysms

Genetic association study identifies a functional CNV in the WWOX gene contributes to the risk of intracranial aneurysms

https://doi.org/10.18632/oncotarget.7546

Jin Fan, Wen Sun, Min Lin, Ke Yu, Jian Wang, Dan Duan, Bo Zheng, Zhenghui Yang,  and Qingsong Wang
16104-16111
Abstract  |  PDF  |  HTML  |  Order a Reprint

Cinacalcet inhibits neuroblastoma tumor growth and upregulates cancer-testis antigens

Cinacalcet inhibits neuroblastoma tumor growth and upregulates cancer-testis antigens

https://doi.org/10.18632/oncotarget.7448

Carlos J. Rodríguez-Hernández, Silvia Mateo-Lozano, Marta García, Carla Casalà, Ferran Briansó, Nerea Castrejón, Eva Rodríguez, Mariona Suñol, Angel M. Carcaboso, Cinzia Lavarino, Jaume Mora,  and Carmen de Torres
16112-16129
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

IL-15 superagonist/IL-15RαSushi-Fc fusion complex (IL-15SA/IL-15RαSu-Fc; ALT-803) markedly enhances specific subpopulations of NK and memory CD8+ T cells, and mediates potent anti-tumor activity against murine breast and colon carcinomas

IL-15 superagonist/IL-15RαSushi-Fc fusion complex (IL-15SA/IL-15RαSu-Fc; ALT-803) markedly enhances specific subpopulations of NK and memory CD8+ T cells, and mediates potent anti-tumor activity against murine breast and colon carcinomas

https://doi.org/10.18632/oncotarget.7470

Peter S. Kim, Anna R. Kwilas, Wenxin Xu, Sarah Alter, Emily K. Jeng, Hing C. Wong, Jeffrey Schlom,  and James W. Hodge
16130-16145
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Soluble Tie2 overrides the heightened invasion induced by anti-angiogenesis therapies in gliomas

Soluble Tie2 overrides the heightened invasion induced by anti-angiogenesis therapies in gliomas

https://doi.org/10.18632/oncotarget.7550

Nahir Cortes-Santiago, Mohammad B. Hossain, Konrad Gabrusiewicz, Xuejun Fan, Joy Gumin, Frank C. Marini, Marta M. Alonso, Frederick Lang, W.K. Yung, Juan Fueyo,  and Candelaria Gomez-Manzano
16146-16157
Abstract  |  PDF  |  HTML  |  Order a Reprint

Epigallocatechin-3-gallate targets cancer stem-like cells and enhances 5-fluorouracil chemosensitivity in colorectal cancer

Epigallocatechin-3-gallate targets cancer stem-like cells and enhances 5-fluorouracil chemosensitivity in colorectal cancer

https://doi.org/10.18632/oncotarget.7567

Shusuke Toden, Hanh-My Tran, Oscar A. Tovar-Camargo, Yoshinaga Okugawa,  and Ajay Goel
16158-16171
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Genetic mutations associated with metastatic clear cell renal cell carcinoma

Genetic mutations associated with metastatic clear cell renal cell carcinoma

https://doi.org/10.18632/oncotarget.7473

Zhongjun Li, Ping Hao, Qingjian Wu, Fengjie Li, Jiang Zhao, Kaijin Wu, Cunye Qu, Yibu Chen, Meng Li, Xuelian Chen, Andres Stucky, Jiangjian Zhong, Longkun Li,  and Jiang F. Zhong
16172-16179
Abstract  |  PDF  |  HTML  |  Order a Reprint

Loss of large tumor suppressor 1 promotes growth and metastasis of gastric cancer cells through upregulation of the YAP signaling

Loss of large tumor suppressor 1 promotes growth and metastasis of gastric cancer cells through upregulation of the YAP signaling

https://doi.org/10.18632/oncotarget.7568

Jing Zhang, Ge Wang, Shao-Jun Chu, Jin-Shui Zhu, Rui Zhang, Wen-Wen Lu, Li-Qiong Xia, Yun-Min Lu, Wei Da,  and Qun Sun
16180-16193
Abstract  |  PDF  |  HTML  |  Order a Reprint

Tongxinluo mitigates atherogenesis by regulating angiogenic factors and inhibiting vasa vasorum neovascularization in apolipoprotein E-deficient mice

Tongxinluo mitigates atherogenesis by regulating angiogenic factors and inhibiting vasa vasorum neovascularization in apolipoprotein E-deficient mice

https://doi.org/10.18632/oncotarget.7477

Lianyue Ma, Mei Ni, Panpan Hao, Huixia Lu, Xiaoyan Yang, Xingli Xu, Cheng Zhang, Shanying Huang, Yuxia Zhao, Xiaoling Liu,  and Yun Zhang
16194-16204
Abstract  |  PDF  |  HTML  |  Order a Reprint

miR-124 downregulation leads to breast cancer progression via LncRNA-MALAT1 regulation and CDK4/E2F1 signal activation

miR-124 downregulation leads to breast cancer progression via LncRNA-MALAT1 regulation and CDK4/E2F1 signal activation

https://doi.org/10.18632/oncotarget.7578

Tongbao Feng, Fang Shao, Qiyong Wu, Xiaohang Zhang, Dongqin Xu, Keqing Qian, Yewen Xie, Shizhong Wang, Ning Xu, Yong Wang,  and Chunjian Qi
16205-16216
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Ribosomal protein L4 is a novel regulator of the MDM2-p53 loop

Ribosomal protein L4 is a novel regulator of the MDM2-p53 loop

https://doi.org/10.18632/oncotarget.7479

Xia He, Yuhuang Li, Mu-Shui Dai,  and Xiao-Xin Sun
16217-16226
Abstract  |  PDF  |  HTML  |  Order a Reprint

Mechanosensitive caveolin-1 activation-induced PI3K/Akt/mTOR signaling pathway promotes breast cancer motility, invadopodia formation and metastasis in vivo

Mechanosensitive caveolin-1 activation-induced PI3K/Akt/mTOR signaling pathway promotes breast cancer motility, invadopodia formation and metastasis in vivo

https://doi.org/10.18632/oncotarget.7583

Hong Yang, Liuyuan Guan, Shun Li, Ying Jiang, Niya Xiong, Li Li, Chunhui Wu, Hongjuan Zeng,  and Yiyao Liu
16227-16247
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Bromodomain-containing protein 7 (BRD7) as a potential tumor suppressor in hepatocellular carcinoma

Bromodomain-containing protein 7 (BRD7) as a potential tumor suppressor in hepatocellular carcinoma

https://doi.org/10.18632/oncotarget.7637

Chang-Long Chen, Ying Wang, Qiu-Zhong Pan, Yan Tang, Qi-Jing Wang, Ke Pan, Li-Xi Huang, Jia He, Jing-Jing Zhao, Shan-Shan Jiang, Xiao-Fei Zhang, Hong-Xia Zhang, Zi-Qi Zhou, De-Sheng Weng,  and Jian-Chuan Xia
16248-16261
Abstract  |  PDF  |  HTML  |  Order a Reprint

Elevated autocrine chemokine ligand 18 expression promotes oral cancer cell growth and invasion via Akt activation

Elevated autocrine chemokine ligand 18 expression promotes oral cancer cell growth and invasion via Akt activation

https://doi.org/10.18632/oncotarget.7585

Xiao Jiang, Juan Wang, Xijuan Chen, Yun Hong, Tong Wu, Xiaobing Chen, Juan Xia,  and Bin Cheng
16262-16272
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Hepatocyte growth factor reduces sensitivity to the epidermal growth factor receptor-tyrosine kinase inhibitor, gefitinib, in lung adenocarcinoma cells harboring wild-type EGFR

Hepatocyte growth factor reduces sensitivity to the epidermal growth factor receptor-tyrosine kinase inhibitor, gefitinib, in lung adenocarcinoma cells harboring wild-type EGFR

https://doi.org/10.18632/oncotarget.7586

Hua Yang, Rong Wang, Shunli Peng, Longhua Chen, Qi Li,  and Wei Wang
16273-16281
Abstract  |  PDF  |  HTML  |  Order a Reprint

A small molecule induces integrin β4 nuclear translocation and apoptosis selectively in cancer cells with high expression of integrin β4

A small molecule induces integrin β4 nuclear translocation and apoptosis selectively in cancer cells with high expression of integrin β4

https://doi.org/10.18632/oncotarget.7646

ShuYan Liu, Di Ge, LiNa Chen, Jing Zhao, Le Su, ShangLi Zhang, JunYing Miao,  and BaoXiang Zhao
16282-16296
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

ANXA11 regulates the tumorigenesis, lymph node metastasis and 5-fluorouracil sensitivity of murine hepatocarcinoma Hca-P cells by targeting c-Jun

ANXA11 regulates the tumorigenesis, lymph node metastasis and 5-fluorouracil sensitivity of murine hepatocarcinoma Hca-P cells by targeting c-Jun

https://doi.org/10.18632/oncotarget.7484

Shuqing Liu, Chunmei Guo, Jiasheng Wang, Bo Wang, Houbao Qi,  and Ming-Zhong Sun
16297-16310
Abstract  |  PDF  |  HTML  |  Order a Reprint

Anti-cancer drug 3,3′-diindolylmethane activates Wnt4 signaling to enhance gastric cancer cell stemness and tumorigenesis

Anti-cancer drug 3,3′-diindolylmethane activates Wnt4 signaling to enhance gastric cancer cell stemness and tumorigenesis

https://doi.org/10.18632/oncotarget.7684

Yanhua Zhu, Bin Zhang, Aihua Gong, Hailong Fu, Xu Zhang, Hui Shi, Yaoxiang Sun, Lijun Wu, Zhaoji Pan, Fei Mao, Wei Zhu, Hui Qian,  and Wenrong Xu
16311-16324
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Cyclic AMP responsive element-binding protein promotes renal cell carcinoma proliferation probably via the expression of spindle and kinetochore-associated protein 2

Cyclic AMP responsive element-binding protein promotes renal cell carcinoma proliferation probably via the expression of spindle and kinetochore-associated protein 2

https://doi.org/10.18632/oncotarget.7017

Haihui Zhuang, Xiangyu Meng, Yanyuan Li, Xue Wang, Shuaishuai Huang, Kaitai Liu, Michael Hehir, Rong Fang, Lei Jiang, Jeff X. Zhou, Ping Wang,  and Yu Ren
16325-16337
Abstract  |  PDF  |  HTML  |  Order a Reprint

Serum protein profiling using an aptamer array predicts clinical outcomes of stage IIA colon cancer: A leave-one-out crossvalidation

Serum protein profiling using an aptamer array predicts clinical outcomes of stage IIA colon cancer: A leave-one-out crossvalidation

https://doi.org/10.18632/oncotarget.7488

Jung Wook Huh, Sung Chun Kim, Insuk Sohn, Sin-Ho Jung,  and Hee Cheol Kim
16338-16348
Abstract  |  PDF  |  HTML  |  Order a Reprint

AMPK-mediated up-regulation of mTORC2 and MCL-1 compromises the anti-cancer effects of aspirin

AMPK-mediated up-regulation of mTORC2 and MCL-1 compromises the anti-cancer effects of aspirin

https://doi.org/10.18632/oncotarget.7648

Mei Gao, Qingbin Kong, Hui Hua, Yancun Yin, Jiao Wang, Ting Luo,  and Yangfu Jiang
16349-16361
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Identification of serologic biomarkers for predicting microvascular invasion in hepatocellular carcinoma

Identification of serologic biomarkers for predicting microvascular invasion in hepatocellular carcinoma

https://doi.org/10.18632/oncotarget.7649

Yuan-Quan Yu, Liang Wang, Yun Jin, Jia-Le Zhou, Yan-Hua Geng, Xing Jin, Xiao-Xiao Zhang, Jun-Jie Yang, Cheng-Ming Qian, Dong-Er Zhou, Da-Ren Liu, Shu-You Peng, Yan Luo, Lei Zheng,  and Jiang-Tao Li
16362-16371
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Epstein-Barr virus glycoprotein gH/gL antibodies complement IgA-viral capsid antigen for diagnosis of nasopharyngeal carcinoma

Epstein-Barr virus glycoprotein gH/gL antibodies complement IgA-viral capsid antigen for diagnosis of nasopharyngeal carcinoma

https://doi.org/10.18632/oncotarget.7688

Rui-Chen Li, Yong Du, Qiu-Yao Zeng, Lin-Quan Tang, Hua Zhang, Yan Li, Wan-Li Liu, Qian Zhong, Mu-Sheng Zeng,  and Xiao-Ming Huang
16372-16383
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Detection of ATRX and IDH1-R132H immunohistochemistry in the progression of 211 paired gliomas

Detection of ATRX and IDH1-R132H immunohistochemistry in the progression of 211 paired gliomas

https://doi.org/10.18632/oncotarget.7650

Jinquan Cai, Ping Zhu, Chuanbao Zhang, Qingbin Li, Zhiliang Wang, Guanzhang Li, Guangzhi Wang, Pei Yang, Jianlong Li, Bo Han, Chuanlu Jiang, Ying Sun,  and Tao Jiang
16384-16395
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

MicroRNA-199a and -214 as potential therapeutic targets in pancreatic stellate cells in pancreatic tumor

MicroRNA-199a and -214 as potential therapeutic targets in pancreatic stellate cells in pancreatic tumor

https://doi.org/10.18632/oncotarget.7651

Praneeth R. Kuninty, Linda Bojmar, Vegard Tjomsland, Marie Larsson, Gert Storm, Arne Östman, Per Sandström,  and Jai Prakash
16396-16408
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

microRNA-206 impairs c-Myc-driven cancer in a synthetic lethal manner by directly inhibiting MAP3K13

microRNA-206 impairs c-Myc-driven cancer in a synthetic lethal manner by directly inhibiting MAP3K13

https://doi.org/10.18632/oncotarget.7653

Han Han, Yuxing Chen, Li Cheng, Edward V. Prochownik,  and Youjun Li
16409-16419
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Prospective evaluation of 64 serum autoantibodies as biomarkers for early detection of colorectal cancer in a true screening setting

Prospective evaluation of 64 serum autoantibodies as biomarkers for early detection of colorectal cancer in a true screening setting

https://doi.org/10.18632/oncotarget.7500

Hongda Chen, Simone Werner, Julia Butt, Inka Zörnig, Phillip Knebel, Angelika Michel, Stefan B. Eichmüller, Dirk Jäger, Tim Waterboer, Michael Pawlita,  and Hermann Brenner
16420-16432
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Epigenetic inactivation of follistatin-like 1 mediates tumor immune evasion in nasopharyngeal carcinoma

Epigenetic inactivation of follistatin-like 1 mediates tumor immune evasion in nasopharyngeal carcinoma

https://doi.org/10.18632/oncotarget.7654

Xiaoying Zhou, Xue Xiao, Tingting Huang, Chunping Du, Shumin Wang, Yingxi Mo, Ning Ma, Mariko Murata, Bo Li, Wensheng Wen, Guangwu Huang, Xianjie Zeng,  and Zhe Zhang
16433-16444
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

VEGFR2 targeted antibody fused with MICA stimulates NKG2D mediated immunosurveillance and exhibits potent anti-tumor activity against breast cancer

VEGFR2 targeted antibody fused with MICA stimulates NKG2D mediated immunosurveillance and exhibits potent anti-tumor activity against breast cancer

https://doi.org/10.18632/oncotarget.7501

Wei Xei, Fang Liu, Youfu Wang, Xueyan Ren, Tong Wang, Zhiguo Chen, Mingying Tang, Fumou Sun, Zhaoting Li, Min Wang,  and Juan Zhang
16445-16461
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

MicroRNA-30a increases tight junction protein expression to suppress the epithelial-mesenchymal transition and metastasis by targeting Slug in breast cancer

MicroRNA-30a increases tight junction protein expression to suppress the epithelial-mesenchymal transition and metastasis by targeting Slug in breast cancer

https://doi.org/10.18632/oncotarget.7656

Chia-Wei Chang, Jyh-Cherng Yu, Yi-Hsien Hsieh, Chung-Chin Yao, Jui-I Chao, Po-Ming Chen, Hsiao-Yen Hsieh, Chia-Ni Hsiung, Hou-Wei Chu, Chen-Yang Shen,  and Chun-Wen Cheng
16462-16478
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

A cancer-favoring oncolytic vaccinia virus shows enhanced suppression of stem-cell like colon cancer

A cancer-favoring oncolytic vaccinia virus shows enhanced suppression of stem-cell like colon cancer

https://doi.org/10.18632/oncotarget.7660

So Young Yoo, Seo Young Bang, Su-Nam Jeong, Dae Hwan Kang,  and Jeong Heo
16479-16489
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Mapping of deletion breakpoints at the CDKN2A locus in melanoma: detection of MTAP-ANRIL fusion transcripts

Mapping of deletion breakpoints at the CDKN2A locus in melanoma: detection of MTAP-ANRIL fusion transcripts

https://doi.org/10.18632/oncotarget.7503

Huaping Xie, P. Sivaramakrishna Rachakonda, Barbara Heidenreich, Eduardo Nagore, Antje Sucker, Kari Hemminki, Dirk Schadendorf,  and Rajiv Kumar
16490-16504
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Aberrant expression of nuclear HDAC3 and cytoplasmic CDH1 predict a poor prognosis for patients with pancreatic cancer

Aberrant expression of nuclear HDAC3 and cytoplasmic CDH1 predict a poor prognosis for patients with pancreatic cancer

https://doi.org/10.18632/oncotarget.7663

Feng Jiao, Hai Hu, Ting Han, Meng Zhuo, Cuncun Yuan, Haiyan Yang, Lei Wang,  and Liwei Wang
16505-16516
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Carfilzomib potentiates CUDC-101-induced apoptosis in anaplastic thyroid cancer

Carfilzomib potentiates CUDC-101-induced apoptosis in anaplastic thyroid cancer

https://doi.org/10.18632/oncotarget.7760

Lisa Zhang, Myriem Boufraqech, Ross Lake,  and Electron Kebebew
16517-16528
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Aquaporin 3 promotes the stem-like properties of gastric cancer cells via Wnt/GSK-3β/β-catenin pathway

Aquaporin 3 promotes the stem-like properties of gastric cancer cells via Wnt/GSK-3β/β-catenin pathway

https://doi.org/10.18632/oncotarget.7664

Yangchun Zhou, Yao Wang, Jianfei Wen, Haijian Zhao, Xuqiang Dong, Zhihong Zhang, Shoulin Wang,  and Lizong Shen
16529-16541
Abstract  |  PDF  |  HTML  |  Order a Reprint

Discovery of plant extracts that greatly delay yeast chronological aging and have different effects on longevity-defining cellular processes

Discovery of plant extracts that greatly delay yeast chronological aging and have different effects on longevity-defining cellular processes

https://doi.org/10.18632/oncotarget.7665

Vicky Lutchman, Younes Medkour, Eugenie Samson, Anthony Arlia-Ciommo, Pamela Dakik, Berly Cortes, Rachel Feldman, Sadaf Mohtashami, Mélissa McAuley, Marisa Chancharoen, Belise Rukundo, Éric Simard,  and Vladimir I. Titorenko
16542-16566
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

miR-155-5p inhibition promotes the transition of bone marrow mesenchymal stem cells to gastric cancer tissue derived MSC-like cells via NF-κB p65 activation

miR-155-5p inhibition promotes the transition of bone marrow mesenchymal stem cells to gastric cancer tissue derived MSC-like cells via NF-κB p65 activation

https://doi.org/10.18632/oncotarget.7767

Mengchu Zhu, Mei Wang, Fang Yang, Yiqing Tian, Jie Cai, Huan Yang, Hailong Fu, Fei Mao, Wei Zhu, Hui Qian,  and Wenrong Xu
16567-16580
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Preclinical activity of selinexor, an inhibitor of XPO1, in sarcoma

Preclinical activity of selinexor, an inhibitor of XPO1, in sarcoma

https://doi.org/10.18632/oncotarget.7667

Robert Nakayama, Yi-Xiang Zhang, Jeffrey T. Czaplinski, Alex J. Anatone, Ewa T. Sicinska, Jonathan A. Fletcher, George D. Demetri,  and Andrew J. Wagner
16581-16592
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Selective killing of gastric cancer cells by a small molecule via targeting TrxR1 and ROS-mediated ER stress activation

Selective killing of gastric cancer cells by a small molecule via targeting TrxR1 and ROS-mediated ER stress activation

https://doi.org/10.18632/oncotarget.7565

Weiqian Chen, Peng Zou, Zhongwei Zhao, Qiaoyou Weng, Xi Chen, Shilong Ying, Qingqing Ye, Zhe Wang, Jiansong Ji,  and Guang Liang
16593-16609
Abstract  |  PDF  |  HTML  |  Order a Reprint

Time trends of neonatal mortality by causes of death in Shenyang, 1997–2014

Time trends of neonatal mortality by causes of death in Shenyang, 1997–2014

https://doi.org/10.18632/oncotarget.7670

Qi-Jun Wu, Li-Li Li, Jing Li, Chen Zhou,  and Yan-Hong Huang
16610-16618
Abstract  |  PDF  |  HTML  |  Order a Reprint

FOXM1 regulates expression of eukaryotic elongation factor 2 kinase and promotes proliferation, invasion and tumorgenesis of human triple negative breast cancer cells

FOXM1 regulates expression of eukaryotic elongation factor 2 kinase and promotes proliferation, invasion and tumorgenesis of human triple negative breast cancer cells

https://doi.org/10.18632/oncotarget.7672

Zuhal Hamurcu, Ahmed Ashour, Nermin Kahraman,  and Bulent Ozpolat
16619-16635
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

p85α promotes nucleolin transcription and subsequently enhances EGFR mRNA stability and EGF-induced malignant cellular transformation

p85α promotes nucleolin transcription and subsequently enhances EGFR mRNA stability and EGF-induced malignant cellular transformation

https://doi.org/10.18632/oncotarget.7674

Qipeng Xie, Xirui Guo, Jiayan Gu, Liping Zhang, Honglei Jin, Haishan Huang, Jingxia Li,  and Chuanshu Huang
16636-16649
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

The targeted histone deacetylase inhibitor tefinostat (CHR-2845) shows selective in vitro efficacy in monocytoid-lineage leukaemias

The targeted histone deacetylase inhibitor tefinostat (CHR-2845) shows selective in vitro efficacy in monocytoid-lineage leukaemias

https://doi.org/10.18632/oncotarget.7692

Joanna Zabkiewicz, Marie Gilmour, Robert Hills, Pares Vyas, Elizabeth Bone, Alan Davidson, Alan Burnett,  and Steven Knapper
16650-16662
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Proteasomal degradation of sphingosine kinase 1 and inhibition of dihydroceramide desaturase by the sphingosine kinase inhibitors, SKi or ABC294640, induces growth arrest in androgen-independent LNCaP-AI prostate cancer cells

Proteasomal degradation of sphingosine kinase 1 and inhibition of dihydroceramide desaturase by the sphingosine kinase inhibitors, SKi or ABC294640, induces growth arrest in androgen-independent LNCaP-AI prostate cancer cells

https://doi.org/10.18632/oncotarget.7693

Melissa McNaughton, Melissa Pitman, Stuart M. Pitson, Nigel J. Pyne,  and Susan Pyne
16663-16675
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

miR-129-3p controls centrosome number in metastatic prostate cancer cells by repressing CP110

miR-129-3p controls centrosome number in metastatic prostate cancer cells by repressing CP110

https://doi.org/10.18632/oncotarget.7572

Irene V. Bijnsdorp, Jasmina Hodzic, Tonny Lagerweij, Bart Westerman, Oscar Krijgsman, Jurjen Broeke, Frederik Verweij, R. Jonas A. Nilsson, Lawrence Rozendaal, Victor W. van Beusechem, Jeroen A. van Moorselaar, Thomas Wurdinger,  and Albert A. Geldof
16676-16687
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

APE1-mediated DNA damage repair provides survival advantage for esophageal adenocarcinoma cells in response to acidic bile salts

APE1-mediated DNA damage repair provides survival advantage for esophageal adenocarcinoma cells in response to acidic bile salts

https://doi.org/10.18632/oncotarget.7696

Jun Hong, Zheng Chen, Dunfa Peng, Alexander Zaika, Frank Revetta, M. Kay Washington, Abbes Belkhiri,  and Wael El-Rifai
16688-16702
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

MiR-652-3p is upregulated in non-small cell lung cancer and promotes proliferation and metastasis by directly targeting Lgl1

MiR-652-3p is upregulated in non-small cell lung cancer and promotes proliferation and metastasis by directly targeting Lgl1

https://doi.org/10.18632/oncotarget.7697

Wenhui Yang, Chengcheng Zhou, Mei Luo, Xuejiao Shi, Yuan Li, Zengmiao Sun, Fang Zhou, Zhaoli Chen,  and Jie He
16703-16715
Abstract  |  PDF  |  HTML  |  Order a Reprint

Radiation exposure, young age, and female gender are associated with high prevalence of RET/PTC1 and RET/PTC3 in papillary thyroid cancer: a meta-analysis

Radiation exposure, young age, and female gender are associated with high prevalence of RET/PTC1 and RET/PTC3 in papillary thyroid cancer: a meta-analysis

https://doi.org/10.18632/oncotarget.7574

Xuan Su, Zhaoqu Li, Caiyun He, Weichao Chen, Xiaoyan Fu,  and Ankui Yang
16716-16730
Abstract  |  PDF  |  HTML  |  Order a Reprint

Preferential targeting of cancer stem cells in the radiosensitizing effect of ABT-737 on HNSCC

Preferential targeting of cancer stem cells in the radiosensitizing effect of ABT-737 on HNSCC

https://doi.org/10.18632/oncotarget.7744

Marion Gilormini, Céline Malesys, Emma Armandy, Patrick Manas, Jean-Baptiste Guy, Nicolas Magné, Claire Rodriguez-Lafrasse,  and Dominique Ardail
16731-16744
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Significance of the NOR1-FOXA1/HDAC2-Slug regulatory network in epithelial-mesenchymal transition of tumor cells

Significance of the NOR1-FOXA1/HDAC2-Slug regulatory network in epithelial-mesenchymal transition of tumor cells

https://doi.org/10.18632/oncotarget.7778

Wei Wang, Mei Yi, Shengnan Chen, Junjun Li, Guo Li, Jianbo Yang, Pan Zheng, Haijing Zhang, Wei Xiong, James B. McCarthy, Guiyuan Li, Xiaoling Li,  and Bo Xiang
16745-16759
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Heterogeneous nuclear ribonucleoproteins A1 and A2 modulate expression of Tid1 isoforms and EGFR signaling in non-small cell lung cancer

Heterogeneous nuclear ribonucleoproteins A1 and A2 modulate expression of Tid1 isoforms and EGFR signaling in non-small cell lung cancer

https://doi.org/10.18632/oncotarget.7606

Chi-Yuan Chen, Chia-Ing Jan, Wen-Chieh Pi, Wen-Lung Wang, Pan-Chyr Yang, Tong-Hong Wang, Rotem Karni,  and Tzu-Chien V. Wang
16760-16772
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Development of a specific affinity-matured exosite inhibitor to MT1-MMP that efficiently inhibits tumor cell invasion in vitro and metastasis in vivo

Development of a specific affinity-matured exosite inhibitor to MT1-MMP that efficiently inhibits tumor cell invasion in vitro and metastasis in vivo

https://doi.org/10.18632/oncotarget.7780

Kenneth A. Botkjaer, Hang Fai Kwok, Mikkel G. Terp, Aneesh Karatt-Vellatt, Salvatore Santamaria, John McCafferty, Peter A. Andreasen, Yoshifumi Itoh, Henrik J. Ditzel,  and Gillian Murphy
16773-16792
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

hnRNP A1-mediated translational regulation of the G quadruplex-containing RON receptor tyrosine kinase mRNA linked to tumor progression

hnRNP A1-mediated translational regulation of the G quadruplex-containing RON receptor tyrosine kinase mRNA linked to tumor progression

https://doi.org/10.18632/oncotarget.7589

Anne Cammas, Magali Lacroix-Triki, Sandra Pierredon, Morgane Le Bras, Jason S. Iacovoni, Marie-Paule Teulade-Fichou, Gilles Favre, Henri Roché, Thomas Filleron, Stefania Millevoi,  and Stéphan Vagner
16793-16805
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Cigarette smoking complements the prognostic value of baseline plasma Epstein-Barr virus deoxyribonucleic acid in patients with nasopharyngeal carcinoma undergoing intensity-modulated radiation therapy: a large-scale retrospective cohort study

Cigarette smoking complements the prognostic value of baseline plasma Epstein-Barr virus deoxyribonucleic acid in patients with nasopharyngeal carcinoma undergoing intensity-modulated radiation therapy: a large-scale retrospective cohort study

https://doi.org/10.18632/oncotarget.7609

Jia-Wei Lv, Yu-Pei Chen, Guan-Qun Zhou, Ling-Long Tang, Yan-Ping Mao, Wen-Fei Li, Rui Guo, Ai-Hua Lin, Jun Ma,  and Ying Sun
16806-16817
Abstract  |  PDF  |  HTML  |  Order a Reprint

Interaction of antihistaminic drugs with human translationally controlled tumor protein (TCTP) as novel approach for differentiation therapy

Interaction of antihistaminic drugs with human translationally controlled tumor protein (TCTP) as novel approach for differentiation therapy

https://doi.org/10.18632/oncotarget.7605

Ean-Jeong Seo,  and Thomas Efferth
16818-16839
Abstract  |  PDF  |  HTML  |  Order a Reprint

Thymic stromal lymphopoietin (TSLP) inhibits human colon tumor growth by promoting apoptosis of tumor cells

Thymic stromal lymphopoietin (TSLP) inhibits human colon tumor growth by promoting apoptosis of tumor cells

https://doi.org/10.18632/oncotarget.7614

Wenjie Yue, Yuli Lin, Xuguang Yang, Bingji Li, Jie Liu,  and Rui He
16840-16854
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Exceptional antineoplastic activity of a dendritic-cell-targeted vaccine loaded with a Listeria peptide proposed against metastatic melanoma

Exceptional antineoplastic activity of a dendritic-cell-targeted vaccine loaded with a Listeria peptide proposed against metastatic melanoma

https://doi.org/10.18632/oncotarget.7806

Ricardo Calderon-Gonzalez, Lucia Bronchalo-Vicente, Javier Freire, Elisabet Frande-Cabanes, Lidia Alaez-Alvarez, Javier Gomez-Roman, Sonsóles Yañez-Diaz,  and Carmen Alvarez-Dominguez
16855-16865
Abstract  |  PDF  |  HTML  |  Order a Reprint

STIM1 plays an important role in TGF-β-induced suppression of breast cancer cell proliferation

STIM1 plays an important role in TGF-β-induced suppression of breast cancer cell proliferation

https://doi.org/10.18632/oncotarget.7619

Huanyi Cheng, Shiqiang Wang,  and Renqing Feng
16866-16878
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Areca nut components stimulate ADAM17, IL-1α, PGE2 and 8-isoprostane production in oral keratinocyte: role of reactive oxygen species, EGF and JAK signaling

Areca nut components stimulate ADAM17, IL-1α, PGE2 and 8-isoprostane production in oral keratinocyte: role of reactive oxygen species, EGF and JAK signaling

https://doi.org/10.18632/oncotarget.7621

Mei-Chi Chang, Chiu-Po Chan, Yi-Jane Chen, Hsiang-Chi Hsien, Ya-Ching Chang, Sin-Yuet Yeung, Po-Yuan Jeng, Ru-Hsiu Cheng, Liang-Jiunn Hahn,  and Jiiang-Huei Jeng
16879-16894
Abstract  |  PDF  |  HTML  |  Order a Reprint

iACP: a sequence-based tool for identifying anticancer peptides

iACP: a sequence-based tool for identifying anticancer peptides

https://doi.org/10.18632/oncotarget.7815

Wei Chen, Hui Ding, Pengmian Feng, Hao Lin,  and Kuo-Chen Chou
16895-16909
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

ISG15 predicts poor prognosis and promotes cancer stem cell phenotype in nasopharyngeal carcinoma

ISG15 predicts poor prognosis and promotes cancer stem cell phenotype in nasopharyngeal carcinoma

https://doi.org/10.18632/oncotarget.7626

Ren-Hui Chen, Yong Du, Ping Han, Hong-Bo Wang, Fa-Ya Liang, Guo-Kai Feng, Ai-Jun Zhou, Mu-Yan Cai, Qian Zhong, Mu-Sheng Zeng,  and Xiao-Ming Huang
16910-16922
Abstract  |  PDF  |  HTML  |  Order a Reprint

Diagnostic and prognostic relevance of circulating exosomal miR-373, miR-200a, miR-200b and miR-200c in patients with epithelial ovarian cancer

Diagnostic and prognostic relevance of circulating exosomal miR-373, miR-200a, miR-200b and miR-200c in patients with epithelial ovarian cancer

https://doi.org/10.18632/oncotarget.7850

Xiaodan Meng, Volkmar Müller, Karin Milde-Langosch, Fabian Trillsch, Klaus Pantel,  and Heidi Schwarzenbach
16923-16935
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

ROCK1 via LIM kinase regulates growth, maturation and actin based functions in mast cells

ROCK1 via LIM kinase regulates growth, maturation and actin based functions in mast cells

https://doi.org/10.18632/oncotarget.7851

Reuben Kapur, Jianjian Shi, Joydeep Ghosh, Veerendra Munugalavadla, Emily Sims, Holly Martin, Lei Wei,  and Raghuveer Singh Mali
16936-16947
Abstract  |  PDF  |  HTML  |  Order a Reprint

Comparative analysis of tumor spheroid generation techniques for differential in vitro drug toxicity

Comparative analysis of tumor spheroid generation techniques for differential in vitro drug toxicity

https://doi.org/10.18632/oncotarget.7659

Shreya Raghavan, Pooja Mehta, Eric N. Horst, Maria R. Ward, Katelyn R. Rowley,  and Geeta Mehta
16948-16961
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

High throughput microscopy identifies bisphenol AP, a bisphenol A analog, as a novel AR down-regulator

High throughput microscopy identifies bisphenol AP, a bisphenol A analog, as a novel AR down-regulator

https://doi.org/10.18632/oncotarget.7655

Fabio Stossi, Radhika D. Dandekar, Michael J. Bolt, Justin Y. Newberg, Maureen G. Mancini, Akash K. Kaushik, Vasanta Putluri, Arun Sreekumar,  and Michael A. Mancini
16962-16974
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Lymph nodes regression grade is a predictive marker for rectal cancer after neoadjuvant therapy and radical surgery

Lymph nodes regression grade is a predictive marker for rectal cancer after neoadjuvant therapy and radical surgery

https://doi.org/10.18632/oncotarget.7703

Jun Li, Jiatian Yuan, Hao Liu, Jie Yin, Sai Liu, Feng Du, Junjie Hu, Ci Li, Xiangke Niu, Bo Lv,  and Shasha Xing
16975-16984
Abstract  |  PDF  |  HTML  |  Order a Reprint

Tumor-associated antigen CAPERα and microvessel density in hepatocellular carcinoma

Tumor-associated antigen CAPERα and microvessel density in hepatocellular carcinoma

https://doi.org/10.18632/oncotarget.7707

Liping Dai, Xuan-Xian Peng, Eng M. Tan,  and Jian-Ying Zhang
16985-16995
Abstract  |  PDF  |  HTML  |  Order a Reprint

Cholesterol consumption and risk of endometrial cancer: a systematic review and dose-response meta-analysis of observational studies

Cholesterol consumption and risk of endometrial cancer: a systematic review and dose-response meta-analysis of observational studies

https://doi.org/10.18632/oncotarget.7913

Ting-Ting Gong, Da Li, Qi-Jun Wu,  and Ya-Zhu Wang
16996-17008
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Oroxylin A modulates mitochondrial function and apoptosis in human colon cancer cells by inducing mitochondrial translocation of wild-type p53

Oroxylin A modulates mitochondrial function and apoptosis in human colon cancer cells by inducing mitochondrial translocation of wild-type p53

https://doi.org/10.18632/oncotarget.7927

Chen Qiao, Na Lu, Yuxin Zhou, Ting Ni, Yuanyuan Dai, Zhiyu Li, Qinglong Guo,  and Libin Wei
17009-17020
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Chronic inflammation contributes to the development of hepatocellular carcinoma by decreasing miR-122 levels

Chronic inflammation contributes to the development of hepatocellular carcinoma by decreasing miR-122 levels

https://doi.org/10.18632/oncotarget.7740

Changfei Li, Mengmeng Deng, Jun Hu, Xin Li, Lizhao Chen, Ying Ju, Junli Hao,  and Songdong Meng
17021-17034
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Intravenous administration of the selective toll-like receptor 7 agonist DSR-29133 leads to anti-tumor efficacy in murine solid tumor models which can be potentiated by combination with fractionated radiotherapy

Intravenous administration of the selective toll-like receptor 7 agonist DSR-29133 leads to anti-tumor efficacy in murine solid tumor models which can be potentiated by combination with fractionated radiotherapy

https://doi.org/10.18632/oncotarget.7928

Simon J. Dovedi, Amy L. Adlard, Yosuke Ota, Masashi Murata, Eiji Sugaru, Erina Koga-Yamakawa, Ken Eguchi, Yuko Hirose, Setsuko Yamamoto, Hiroki Umehara, Jamie Honeychurch, Eleanor J. Cheadle, Gareth Hughes, Philip J. Jewsbury, Robert W. Wilkinson, Ian J. Stratford,  and Timothy M. Illidge
17035-17046
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

KU-0060648 inhibits hepatocellular carcinoma cells through DNA-PKcs-dependent and DNA-PKcs-independent mechanisms

KU-0060648 inhibits hepatocellular carcinoma cells through DNA-PKcs-dependent and DNA-PKcs-independent mechanisms

https://doi.org/10.18632/oncotarget.7742

Min-Bin Chen, Zhen-Tao Zhou, Lan Yang, Mu-Xin Wei, Min Tang, Ting-Yan Ruan, Jun-Ying Xu, Xiao-zhong Zhou, Gang Chen,  and Pei-Hua Lu
17047-17059
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Combination of metronomic cyclophosphamide and dietary intervention inhibits neuroblastoma growth in a CD1-nu mouse model

Combination of metronomic cyclophosphamide and dietary intervention inhibits neuroblastoma growth in a CD1-nu mouse model

https://doi.org/10.18632/oncotarget.7929

Raphael Johannes Morscher, Sepideh Aminzadeh-Gohari, Cornelia Hauser-Kronberger, René Günther Feichtinger, Wolfgang Sperl,  and Barbara Kofler
17060-17073
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

VEGF promotes gastric cancer development by upregulating CRMP4

VEGF promotes gastric cancer development by upregulating CRMP4

https://doi.org/10.18632/oncotarget.7717

Sile Chen, Xinhua Zhang, Jianjun Peng, Ertao Zhai, Yulong He, Hui Wu, Chuangqi Chen, Jinping Ma, Zhao Wang,  and Shirong Cai
17074-17086
Abstract  |  PDF  |  HTML  |  Order a Reprint

Genomic characterization of patient-derived xenograft models established from fine needle aspirate biopsies of a primary pancreatic ductal adenocarcinoma and from patient-matched metastatic sites

Genomic characterization of patient-derived xenograft models established from fine needle aspirate biopsies of a primary pancreatic ductal adenocarcinoma and from patient-matched metastatic sites

https://doi.org/10.18632/oncotarget.7718

Robert J. Allaway, Dawn A. Fischer, Francine B. de Abreu, Timothy B. Gardner, Stuart R. Gordon, Richard J. Barth, Thomas A. Colacchio, Matthew Wood, Balint Z. Kacsoh, Stephanie J. Bouley, Jingxuan Cui, Joanna Hamilton, Jungbin A. Choi, Joshua T. Lange, Jason D. Peterson, Vijayalakshmi Padmanabhan, Craig R. Tomlinson, Gregory J. Tsongalis, Arief A. Suriawinata, Casey S. Greene, Yolanda Sanchez,  and Kerrington D. Smith
17087-17102
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Therapy of pancreatic cancer via an EphA2 receptor-targeted delivery of gemcitabine

Therapy of pancreatic cancer via an EphA2 receptor-targeted delivery of gemcitabine

https://doi.org/10.18632/oncotarget.7931

Bridget A. Quinn, Si Wang, Elisa Barile, Swadesh K. Das, Luni Emdad, Devanand Sarkar, Surya K. De, Susan Kharagh Morvaridi, John L. Stebbins, Stephen J. Pandol, Paul B. Fisher,  and Maurizio Pellecchia
17103-17110
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Tumor-promoting function and prognostic significance of the RNA-binding protein T-cell intracellular antigen-1 in esophageal squamous cell carcinoma

Tumor-promoting function and prognostic significance of the RNA-binding protein T-cell intracellular antigen-1 in esophageal squamous cell carcinoma

https://doi.org/10.18632/oncotarget.7937

Junichi Hamada, Katsutoshi Shoda, Kiyoshi Masuda, Yuji Fujita, Takuya Naruto, Tomohiro Kohmoto, Yuko Miyakami, Miki Watanabe, Yasusei Kudo, Hitoshi Fujiwara, Daisuke Ichikawa, Eigo Otsuji,  and Issei Imoto
17111-17128
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

N52 monodeamidated Bcl‑xL shows impaired oncogenic properties in vivo and in vitro

N52 monodeamidated Bcl‑xL shows impaired oncogenic properties in vivo and in vitro

https://doi.org/10.18632/oncotarget.7938

Florian Beaumatin, Mohamad El Dhaybi, Jean-Paul Lasserre, Bénédicte Salin, Mary Pat Moyer, Mireille Verdier, Stéphen Manon,  and Muriel Priault
17129-17143
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

MMP-13 is involved in oral cancer cell metastasis

MMP-13 is involved in oral cancer cell metastasis

https://doi.org/10.18632/oncotarget.7942

Shun-Hong Huang, Ching-Hsuan Law, Ping-Hsueh Kuo, Ren-Yu Hu, Ching-Chieh Yang, Ting-Wen Chung, Ji-Min Li, Li-Hsun Lin, Yi-Chung Liu, En-Chi Liao, Yi-Ting Tsai, Yu-Shan Wei, Chi-Chen Lin, Chien-Wen Chang, Hsiu-Chuan Chou, Wen-Ching Wang, Margaret Dah-Tsyr Chang, Lu-Hai Wang, Hsing-Jien Kung, Hong-Lin Chan,  and Ping-Chiang Lyu
17144-17161
Abstract  |  PDF  |  HTML  |  Order a Reprint

ER maleate is a novel anticancer agent in oral cancer: implications for cancer therapy

ER maleate is a novel anticancer agent in oral cancer: implications for cancer therapy

https://doi.org/10.18632/oncotarget.7751

Guodong Fu, Raj Thani Somasundaram, Fatima Jessa, Gunjan Srivastava, Christina MacMillan, Ian Witterick, Paul G. Walfish,  and Ranju Ralhan
17162-17181
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Association of helicobacter pylori infection and chronic atrophic gastritis with risk of colonic, pancreatic and gastric cancer: A ten-year follow-up of the ESTHER cohort study

Association of helicobacter pylori infection and chronic atrophic gastritis with risk of colonic, pancreatic and gastric cancer: A ten-year follow-up of the ESTHER cohort study

https://doi.org/10.18632/oncotarget.7946

Xin-Zu Chen, Ben Schöttker, Felipe Andres Castro, Hongda Chen, Yan Zhang, Bernd Holleczek,  and Hermann Brenner
17182-17193
Abstract  |  PDF  |  HTML  |  Order a Reprint

Combining BRAF inhibitor and anti PD-L1 antibody dramatically improves tumor regression and anti tumor immunity in an immunocompetent murine model of anaplastic thyroid cancer

Combining BRAF inhibitor and anti PD-L1 antibody dramatically improves tumor regression and anti tumor immunity in an immunocompetent murine model of anaplastic thyroid cancer

https://doi.org/10.18632/oncotarget.7839

Eran Brauner, Viswanath Gunda, Pierre Vanden Borre, David Zurakowski, Yon Seon Kim, Kate Virginia Dennett, Salma Amin, Gordon James Freeman,  and Sareh Parangi
17194-17211
Abstract  |  PDF  |  HTML  |  Order a Reprint

TIKI2 is upregulated and plays an oncogenic role in renal cell carcinoma

TIKI2 is upregulated and plays an oncogenic role in renal cell carcinoma

https://doi.org/10.18632/oncotarget.7873

Xiaodong Yuan, Baijun Dong, Yunze Xu, Liang Dong, Jiwei Huang, Jin Zhang, Yonghui Chen, Wei Xue,  and Yiran Huang
17212-17219
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Apatinib inhibits VEGF signaling and promotes apoptosis in intrahepatic cholangiocarcinoma

Apatinib inhibits VEGF signaling and promotes apoptosis in intrahepatic cholangiocarcinoma

https://doi.org/10.18632/oncotarget.7948

Hong Peng, Qiuyang Zhang, Jiali Li, Ning Zhang, Yunpeng Hua, Lixia Xu, Yubin Deng, Jiaming Lai, Zhenwei Peng, Baogang Peng, Minhu Chen, Sui Peng,  and Ming Kuang
17220-17229
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Clinical Research Papers

Impact of cytomegalovirus reactivation on relapse and survival in patients with acute leukemia who received allogeneic hematopoietic stem cell transplantation in first remission

Impact of cytomegalovirus reactivation on relapse and survival in patients with acute leukemia who received allogeneic hematopoietic stem cell transplantation in first remission

https://doi.org/10.18632/oncotarget.7347

Jae-Ho Yoon, Seok Lee, Hee-Je Kim, Young-Woo Jeon, Sung-Eun Lee, Byung-Sik Cho, Dong-Gun Lee, Ki-Seong Eom, Yoo-Jin Kim, Chang-Ki Min, Seok-Goo Cho, Woo-Sung Min,  and Jong Wook Lee
17230-17241
Abstract  |  PDF  |  HTML  |  Order a Reprint

Combined analysis of circulating epithelial cells and serum thyroglobulin for distinguishing disease status of the patients with papillary thyroid carcinoma

Combined analysis of circulating epithelial cells and serum thyroglobulin for distinguishing disease status of the patients with papillary thyroid carcinoma

https://doi.org/10.18632/oncotarget.6587

Hung-Chih Lin, Miaw-Jene Liou, Hsung-Ling Hsu, Jason Chia-Hsun Hsieh, Yi-An Chen, Ching-Ping Tseng,  and Jen-Der Lin
17242-17253
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

MR imaging biomarkers for evaluating therapeutic effects shortly after near infrared photoimmunotherapy

MR imaging biomarkers for evaluating therapeutic effects shortly after near infrared photoimmunotherapy

https://doi.org/10.18632/oncotarget.7357

Yuko Nakamura, Marcelino Bernardo, Tadanobu Nagaya, Kazuhide Sato, Toshiko Harada, Peter L. Choyke,  and Hisataka Kobayashi
17254-17264
Abstract  |  PDF  |  HTML  |  Order a Reprint

Clinicopathologic distribution of KRAS and BRAF mutations in a Chinese population with colorectal cancer precursor lesions

Clinicopathologic distribution of KRAS and BRAF mutations in a Chinese population with colorectal cancer precursor lesions

https://doi.org/10.18632/oncotarget.7504

Chenghao Yi, Yanqing Huang, Xing Yu, Xiaofen Li, Shu Zheng, Kefeng Ding,  and Jinghong Xu
17265-17274
Abstract  |  PDF  |  HTML  |  Order a Reprint

Nomograms for predicting Gleason upgrading in a contemporary Chinese cohort receiving radical prostatectomy after extended prostate biopsy: development and internal validation

Nomograms for predicting Gleason upgrading in a contemporary Chinese cohort receiving radical prostatectomy after extended prostate biopsy: development and internal validation

https://doi.org/10.18632/oncotarget.7787

Biming He, Rui Chen, Xu Gao, Shancheng Ren, Bo Yang, Jianguo Hou, Linhui Wang, Qing Yang, Tie Zhou, Lin Zhao, Chuanliang Xu,  and Yinghao Sun
17275-17285
Abstract  |  PDF  |  HTML  |  Order a Reprint


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