Oncotarget

Vol 7, No 12

March 22, 2016

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Camptothecin targets WRN protein: mechanism and relevance in clinical breast cancer. See Shamanna et al. 

Table of Contents

Priority Research Papers

Camptothecin targets WRN protein: mechanism and relevance in clinical breast cancer

Camptothecin targets WRN protein: mechanism and relevance in clinical breast cancer

https://doi.org/10.18632/oncotarget.7906

Raghavendra A. Shamanna, Huiming Lu, Deborah L. Croteau, Arvind Arora, Devika Agarwal, Graham Ball, Mohammed A. Aleskandarany, Ian O. Ellis, Yves Pommier, Srinivasan Madhusudan,  and Vilhelm A. Bohr
13269-13284
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Video Interview with Dr. Vilhelm A. Bohr  |  Order a Reprint

Research Papers: Gerotarget (Focus on Aging)

Increased IL-6 secretion by aged human mesenchymal stromal cells disrupts hematopoietic stem and progenitor cells’ homeostasis

Increased IL-6 secretion by aged human mesenchymal stromal cells disrupts hematopoietic stem and progenitor cells’ homeostasis

https://doi.org/10.18632/oncotarget.7690

Kelsey O’Hagan-Wong, Stéphanie Nadeau, Audrey Carrier-Leclerc, Felipe Apablaza, Reggie Hamdy, Dominique Shum-Tim, Francis Rodier,  and Inés Colmegna
13285-13296
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

A multimodal assessment of balance in elderly and young adults

A multimodal assessment of balance in elderly and young adults

https://doi.org/10.18632/oncotarget.7758

Gregory W. King, Eduardo L. Abreu, An-Lin Cheng, Keyna K. Chertoff, Leticia Brotto, Patricia J. Kelly,  and Marco Brotto
13297-13306
Abstract  |  PDF  |  HTML  |  Order a Reprint

Aging is a weak but relentless determinant of dementia severity

Aging is a weak but relentless determinant of dementia severity

https://doi.org/10.18632/oncotarget.7759

Donald R. Royall,  and Raymond F. Palmer
13307-13318
Abstract  |  PDF  |  HTML  |  Order a Reprint

Effect of HMGCR genetic variation on neuroimaging biomarkers in healthy, mild cognitive impairment and Alzheimer’s disease cohorts

Effect of HMGCR genetic variation on neuroimaging biomarkers in healthy, mild cognitive impairment and Alzheimer’s disease cohorts

https://doi.org/10.18632/oncotarget.7797

Lei Cao, Hui-Fu Wang, Lin Tan, Fu-Rong Sun, Meng-Shan Tan, Chen-Chen Tan, Teng Jiang, Jin-Tai Yu, Lan Tan,  and Alzheimer’s Disease Neuroimaging Initiative
13319-13327
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Escitalopram attenuates β-amyloid-induced tau hyperphosphorylation in primary hippocampal neurons through the 5-HT1A receptor mediated Akt/GSK-3β pathway

Escitalopram attenuates β-amyloid-induced tau hyperphosphorylation in primary hippocampal neurons through the 5-HT1A receptor mediated Akt/GSK-3β pathway

https://doi.org/10.18632/oncotarget.7798

Yan-Juan Wang, Qing-Guo Ren, Wei-Gang Gong, Di Wu, Xiang Tang, Xiao-Li Li, Fang-Fang Wu, Feng Bai, Lin Xu,  and Zhi-Jun Zhang
13328-13339
Abstract  |  PDF  |  HTML  |  Order a Reprint

Age-related changes in the transcriptome of antibody-secreting cells

Age-related changes in the transcriptome of antibody-secreting cells

https://doi.org/10.18632/oncotarget.7958

Senthil Kannan, Noor Dawany, Raj Kurupati, Louise C. Showe,  and Hildegund C.J. Ertl
13340-13353
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Increased amyloid β-peptide uptake in skeletal muscle is induced by hyposialylation and may account for apoptosis in GNE myopathy

Increased amyloid β-peptide uptake in skeletal muscle is induced by hyposialylation and may account for apoptosis in GNE myopathy

https://doi.org/10.18632/oncotarget.7997

Mònica Bosch-Morató, Cinta Iriondo, Biuse Guivernau, Victòria Valls-Comamala, Noemí Vidal, Montse Olivé, Henry Querfurth,  and Francisco J. Muñoz
13354-13371
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Research Papers: Pathology

Clinicopathologic, molecular, and prognostic implications of the loss of EPCAM expression in colorectal carcinoma

Clinicopathologic, molecular, and prognostic implications of the loss of EPCAM expression in colorectal carcinoma

https://doi.org/10.18632/oncotarget.5618

Jung Ho Kim, Jeong Mo Bae, Young Seok Song, Nam-Yun Cho, Hye Seung Lee,  and Gyeong Hoon Kang
13372-13387
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

High circulating activin A level is associated with tumor progression and predicts poor prognosis in lung adenocarcinoma

High circulating activin A level is associated with tumor progression and predicts poor prognosis in lung adenocarcinoma

https://doi.org/10.18632/oncotarget.7796

Mir Alireza Hoda, Anita Rozsas, Elisabeth Lang, Thomas Klikovits, Zoltan Lohinai, Szilvia Torok, Judit Berta, Matyas Bendek, Walter Berger, Balazs Hegedus, Walter Klepetko, Ferenc Renyi-Vamos, Michael Grusch, Balazs Dome,  and Viktoria Laszlo
13388-13399
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Research Papers: Immunology

Chronic Trypanosoma cruzi infection potentiates adipose tissue macrophage polarization toward an anti-inflammatory M2 phenotype and contributes to diabetes progression in a diet-induced obesity model

Chronic Trypanosoma cruzi infection potentiates adipose tissue macrophage polarization toward an anti-inflammatory M2 phenotype and contributes to diabetes progression in a diet-induced obesity model

https://doi.org/10.18632/oncotarget.7630

María E. Cabalén, María F. Cabral, Liliana M. Sanmarco, Marta C. Andrada, Luisina I. Onofrio, Nicolás E. Ponce, María P. Aoki, Susana Gea,  and Roxana C. Cano
13400-13415
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Comparative analysis of human and mouse transcriptomes of Th17 cell priming

Comparative analysis of human and mouse transcriptomes of Th17 cell priming

https://doi.org/10.18632/oncotarget.7963

Soile Tuomela, Sini Rautio, Helena Ahlfors, Viveka Öling, Verna Salo, Ubaid Ullah, Zhi Chen, Saara Hämälistö, Subhash K. Tripathi, Tarmo Äijö, Omid Rasool, Hayssam Soueidan, Lodewyk Wessels, Brigitta Stockinger, Harri Lähdesmäki,  and Riitta Lahesmaa
13416-13428
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Research Papers: Chromosome

Comprehensive nucleosome mapping of the human genome in cancer progression

Comprehensive nucleosome mapping of the human genome in cancer progression

https://doi.org/10.18632/oncotarget.6811

Brooke R. Druliner, Daniel Vera, Ruth Johnson, Xiaoyang Ruan, Lynn M. Apone, Eileen T. Dimalanta, Fiona J. Stewart, Lisa Boardman,  and Jonathan H. Dennis
13429-13445
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Reviews

Aptamers: A promising chemical antibody for cancer therapy

Aptamers: A promising chemical antibody for cancer therapy

https://doi.org/10.18632/oncotarget.7178

Gang Zhou, George Wilson, Lionel Hebbard, Wei Duan, Christopher Liddle, Jacob George,  and Liang Qiao
13446-13463
Abstract  |  PDF  |  HTML  |  Order a Reprint

Targeting hypoxic response for cancer therapy

Targeting hypoxic response for cancer therapy

https://doi.org/10.18632/oncotarget.7229

Elisa Paolicchi, Federica Gemignani, Marija Krstic-Demonacos, Shoukat Dedhar, Luciano Mutti,  and Stefano Landi
13464-13478
Abstract  |  PDF  |  HTML  |  Order a Reprint

Competing endogenous RNA networks in human cancer: hypothesis, validation, and perspectives

Competing endogenous RNA networks in human cancer: hypothesis, validation, and perspectives

https://doi.org/10.18632/oncotarget.7266

Chao Yang, Di Wu, Lin Gao, Xi Liu, Yinji Jin, Dong Wang, Tianzhen Wang,  and Xiaobo Li
13479-13490
Abstract  |  PDF  |  HTML  |  Order a Reprint

Research Papers

miR-449a promotes liver cancer cell apoptosis by downregulation of Calpain 6 and POU2F1

miR-449a promotes liver cancer cell apoptosis by downregulation of Calpain 6 and POU2F1

https://doi.org/10.18632/oncotarget.4821

Yonglei Liu, Yutong Wang, Xiangjun Sun, Chuanzhong Mei, Liying Wang, Zengxia Li,  and Xiliang Zha
13491-13501
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

A double feedback loop mediated by microRNA-23a/27a/24-2 regulates M1 versus M2 macrophage polarization and thus regulates cancer progression

A double feedback loop mediated by microRNA-23a/27a/24-2 regulates M1 versus M2 macrophage polarization and thus regulates cancer progression

https://doi.org/10.18632/oncotarget.6284

Sisi Ma, Min Liu, Zhenbiao Xu, Yanshuang Li, Hui Guo, Yehua Ge, Yanxin Liu, Dexian Zheng,  and Juan Shi
13502-13519
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

KIAA0101 is associated with human renal cell carcinoma proliferation and migration induced by erythropoietin

KIAA0101 is associated with human renal cell carcinoma proliferation and migration induced by erythropoietin

https://doi.org/10.18632/oncotarget.5876

Shengjun Fan, Xin Li, Lu Tie, Yan Pan,  and Xuejun Li
13520-13537
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

SIRT1 inhibition impairs non-homologous end joining DNA damage repair by increasing Ku70 acetylation in chronic myeloid leukemia cells

SIRT1 inhibition impairs non-homologous end joining DNA damage repair by increasing Ku70 acetylation in chronic myeloid leukemia cells

https://doi.org/10.18632/oncotarget.6455

Wenjun Zhang, Haixia Wu, Meng Yang, Shiguang Ye, Liang Li, Hong Zhang, Jiong Hu, Xuguang Wang, Jun Xu,  and Aibin Liang
13538-13550
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Low expression of CD200 predicts shorter time-to-treatment in chronic lymphocytic leukemia

Low expression of CD200 predicts shorter time-to-treatment in chronic lymphocytic leukemia

https://doi.org/10.18632/oncotarget.6948

Yi Miao, Lei Fan, Yu-Jie Wu, Yi Xia, Chun Qiao, Yan Wang, Li Wang, Min Hong, Hua-Yuan Zhu, Wei Xu,  and Jian-Yong Li
13551-13562
Abstract  |  PDF  |  HTML  |  Order a Reprint

Disruption of CCL20-CCR6 interaction inhibits metastasis of advanced cutaneous T-cell lymphoma

Disruption of CCL20-CCR6 interaction inhibits metastasis of advanced cutaneous T-cell lymphoma

https://doi.org/10.18632/oncotarget.6916

Sho Ikeda, Akihiro Kitadate, Mitsugu Ito, Fumito Abe, Miho Nara, Atsushi Watanabe, Naoto Takahashi, Tomomitsu Miyagaki, Makoto Sugaya,  and Hiroyuki Tagawa
13563-13574
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

FGF19 promotes epithelial-mesenchymal transition in hepatocellular carcinoma cells by modulating the GSK3β/β- catenin signaling cascade via FGFR4 activation

FGF19 promotes epithelial-mesenchymal transition in hepatocellular carcinoma cells by modulating the GSK3β/β- catenin signaling cascade via FGFR4 activation

https://doi.org/10.18632/oncotarget.6185

Huakan Zhao, Fenglin Lv, Guizhao Liang, Xiaobin Huang, Gang Wu, Wenfa Zhang, Le Yu, Lei Shi,  and Yong Teng
13575-13586
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Association and prognostic significance of BRCA1/2-mutation status with neoantigen load, number of tumor-infiltrating lymphocytes and expression of PD-1/PD-L1 in high grade serous ovarian cancer

Association and prognostic significance of BRCA1/2-mutation status with neoantigen load, number of tumor-infiltrating lymphocytes and expression of PD-1/PD-L1 in high grade serous ovarian cancer

https://doi.org/10.18632/oncotarget.7277

Kyle C. Strickland, Brooke E. Howitt, Sachet A. Shukla, Scott Rodig, Lauren L. Ritterhouse, Joyce F. Liu, Judy E. Garber, Dipanjan Chowdhury, Catherine J. Wu, Alan D. D’Andrea, Ursula A. Matulonis,  and Panagiotis A. Konstantinopoulos
13587-13598
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

ERβ decreases the invasiveness of triple-negative breast cancer cells by regulating mutant p53 oncogenic function

ERβ decreases the invasiveness of triple-negative breast cancer cells by regulating mutant p53 oncogenic function

https://doi.org/10.18632/oncotarget.7300

Igor Bado, Fotis Nikolos, Gayani Rajapaksa, Jan-Åke Gustafsson,  and Christoforos Thomas
13599-13611
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Establishment of an integrated model incorporating standardised uptake value and N-classification for predicting metastasis in nasopharyngeal carcinoma

Establishment of an integrated model incorporating standardised uptake value and N-classification for predicting metastasis in nasopharyngeal carcinoma

https://doi.org/10.18632/oncotarget.7253

Yuan Zhang, Wen-Fei Li, Yan-Ping Mao, Guan-Qun Zhou, Hao Peng, Ying Sun, Qing Liu, Lei Chen,  and Jun Ma
13612-13620
Abstract  |  PDF  |  HTML  |  Order a Reprint

Effective growth-suppressive activity of maternal embryonic leucine-zipper kinase (MELK) inhibitor against small cell lung cancer

Effective growth-suppressive activity of maternal embryonic leucine-zipper kinase (MELK) inhibitor against small cell lung cancer

https://doi.org/10.18632/oncotarget.7297

Hiroyuki Inoue, Taigo Kato, Sope Olugbile, Kenji Tamura, Suyoun Chung, Takashi Miyamoto, Yo Matsuo, Ravi Salgia, Yusuke Nakamura,  and Jae-Hyun Park
13621-13633
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Upregulated TRIM29 promotes proliferation and metastasis of nasopharyngeal carcinoma via PTEN/AKT/mTOR signal pathway

Upregulated TRIM29 promotes proliferation and metastasis of nasopharyngeal carcinoma via PTEN/AKT/mTOR signal pathway

https://doi.org/10.18632/oncotarget.7215

Xiao-Min Zhou, Rui Sun, Dong-Hua Luo, Jian Sun, Mei-Yin Zhang, Meng-He Wang, Yang Yang, Hui-Yun Wang,  and Shi-Juan Mai
13634-13650
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Hyperinsulinemia enhances interleukin-17-induced inflammation to promote prostate cancer development in obese mice through inhibiting glycogen synthase kinase 3-mediated phosphorylation and degradation of interleukin-17 receptor

Hyperinsulinemia enhances interleukin-17-induced inflammation to promote prostate cancer development in obese mice through inhibiting glycogen synthase kinase 3-mediated phosphorylation and degradation of interleukin-17 receptor

https://doi.org/10.18632/oncotarget.7296

Sen Liu, Qiuyang Zhang, Chong Chen, Dongxia Ge, Yine Qu, Rongyi Chen, Yi-Ming Fan, Nan Li, Wendell W. Tang, Wensheng Zhang, Kun Zhang, Alun R. Wang, Brian G. Rowan, Steven M. Hill, Oliver Sartor, Asim B. Abdel-Mageed, Leann Myers, Qishan Lin,  and Zongbing You
13651-13666
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Metastatic pathway-specific transcriptome analysis identifies MFSD4 as a putative tumor suppressor and biomarker for hepatic metastasis in patients with gastric cancer

Metastatic pathway-specific transcriptome analysis identifies MFSD4 as a putative tumor suppressor and biomarker for hepatic metastasis in patients with gastric cancer

https://doi.org/10.18632/oncotarget.7269

Mitsuro Kanda, Dai Shimizu, Haruyoshi Tanaka, Masahiro Shibata, Naoki Iwata, Masamichi Hayashi, Daisuke Kobayashi, Chie Tanaka, Suguru Yamada, Tsutomu Fujii, Goro Nakayama, Hiroyuki Sugimoto, Masahiko Koike, Michitaka Fujiwara,  and Yasuhiro Kodera
13667-13679
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Comparison of the RECIST 1.0 and RECIST 1.1 in patients treated with targeted agents: a pooled analysis and review

Comparison of the RECIST 1.0 and RECIST 1.1 in patients treated with targeted agents: a pooled analysis and review

https://doi.org/10.18632/oncotarget.7322

Jung Han Kim
13680-13687
Abstract  |  PDF  |  HTML  |  Order a Reprint

CRP2, a new invadopodia actin bundling factor critically promotes breast cancer cell invasion and metastasis

CRP2, a new invadopodia actin bundling factor critically promotes breast cancer cell invasion and metastasis

https://doi.org/10.18632/oncotarget.7327

Céline Hoffmann, Xianqing Mao, Monika Dieterle, Flora Moreau, Antoun Al Absi, André Steinmetz, Anaïs Oudin, Guy Berchem, Bassam Janji,  and Clément Thomas
13688-13705
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

MRTF/SRF dependent transcriptional regulation of TAZ in breast cancer cells

MRTF/SRF dependent transcriptional regulation of TAZ in breast cancer cells

https://doi.org/10.18632/oncotarget.7333

Chen-Ying Liu, Siew Wee Chan, Fusheng Guo, Aleksandra Toloczko, Long Cui,  and Wanjin Hong
13706-13716
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Single nucleotide polymorphism in the microRNA-199a binding site of HIF1A gene is associated with pancreatic ductal adenocarcinoma risk and worse clinical outcomes

Single nucleotide polymorphism in the microRNA-199a binding site of HIF1A gene is associated with pancreatic ductal adenocarcinoma risk and worse clinical outcomes

https://doi.org/10.18632/oncotarget.7263

Xiuchao Wang, He Ren, Tiansuo Zhao, Weidong Ma, Jie Dong, Shengjie Zhang, Wen Xin, Shengyu Yang, Li Jia,  and Jihui Hao
13717-13729
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Global proteomic profiling in multistep hepatocarcinogenesis and identification of PARP1 as a novel molecular marker in hepatocellular carcinoma

Global proteomic profiling in multistep hepatocarcinogenesis and identification of PARP1 as a novel molecular marker in hepatocellular carcinoma

https://doi.org/10.18632/oncotarget.7316

Xiao Xu, Zhikun Liu, Jianguo Wang, Haiyang Xie, Jie Li, Jili Cao, Lin Zhou,  and Shusen Zheng
13730-13741
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

BAP1 suppresses lung cancer progression and is inhibited by miR-31

BAP1 suppresses lung cancer progression and is inhibited by miR-31

https://doi.org/10.18632/oncotarget.7328

Mengchao Yu, Hongwei Liang, Zheng Fu, Xueliang Wang, Zhicong Liao, Yong Zhou, Yanqing Liu, Yanbo Wang, Yeting Hong, Xinyan Zhou, Xin Yan, Min Yu, Miao Ma, Weijie Zhang, Baoliang Guo, Jianguo Zhang, Ke Zen, Chen-Yu Zhang, Tao Wang, Qipeng Zhang,  and Xi Chen
13742-13753
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Predictive value of GGN and CAG repeat polymorphisms of androgen receptors in testicular cancer: a meta-analysis

Predictive value of GGN and CAG repeat polymorphisms of androgen receptors in testicular cancer: a meta-analysis

https://doi.org/10.18632/oncotarget.7337

Weijun Jiang, Jing Zhang, Qing Zhou, Shuaimei Liu, Mengxia Ni, Peiran Zhu, Qiuyue Wu, Weiwei Li, Mingchao Zhang,  and Xinyi Xia
13754-13764
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Prognostic and predictive value of tumor-infiltrating lymphocytes for clinical therapeutic research in patients with non-small cell lung cancer

Prognostic and predictive value of tumor-infiltrating lymphocytes for clinical therapeutic research in patients with non-small cell lung cancer

https://doi.org/10.18632/oncotarget.7282

Dong-Qiang Zeng, Yun-Fang Yu, Qi-Yun Ou, Xiao-Yin Li, Ru-Zhi Zhong, Chuan-Miao Xie,  and Qiu-Gen Hu
13765-13781
Abstract  |  PDF  |  HTML  |  Order a Reprint

Antibody h-R3-dendrimer mediated siRNA has excellent endosomal escape and tumor targeted delivery ability, and represents efficient siPLK1 silencing and inhibition of cell proliferation, migration and invasion

Antibody h-R3-dendrimer mediated siRNA has excellent endosomal escape and tumor targeted delivery ability, and represents efficient siPLK1 silencing and inhibition of cell proliferation, migration and invasion

https://doi.org/10.18632/oncotarget.7368

Jun Li, Jing Liu, Shengnan Li, Yanli Hao, Lei Chen,  and Xiaoning Zhang
13782-13796
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Integrated genomic approaches identify upregulation of SCRN1 as a novel mechanism associated with acquired resistance to erlotinib in PC9 cells harboring oncogenic EGFR mutation

Integrated genomic approaches identify upregulation of SCRN1 as a novel mechanism associated with acquired resistance to erlotinib in PC9 cells harboring oncogenic EGFR mutation

https://doi.org/10.18632/oncotarget.7318

Nayoung Kim, Ahye Cho, Hideo Watanabe, Yoon-La Choi, Meraj Aziz, Michelle Kassner, Je-Gun Joung, Angela Kyung-Joo Park, Joshua M. Francis, Joon Seol Bae, Soo-min Ahn, Kyoung-Mee Kim, Joon Oh Park, Woong-Yang Park, Myung-Ju Ahn, Keunchil Park, Jaehyung Koo, Hongwei Holly Yin,  and Jeonghee Cho
13797-13809
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Long noncoding RNA Saf and splicing factor 45 increase soluble Fas and resistance to apoptosis

Long noncoding RNA Saf and splicing factor 45 increase soluble Fas and resistance to apoptosis

https://doi.org/10.18632/oncotarget.7329

Olga Villamizar, Christopher B. Chambers, Janice M. Riberdy, Derek A. Persons,  and Andrew Wilber
13810-13826
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Nuclear localization of TEF3-1 promotes cell cycle progression and angiogenesis in cancer

Nuclear localization of TEF3-1 promotes cell cycle progression and angiogenesis in cancer

https://doi.org/10.18632/oncotarget.7342

Kaixuan Teng, Cuilan Deng, Jie Xu, Qiuxu Men, Tao Lei, Da Di, Ting Liu, Wenhua Li,  and Xin Liu
13827-13841
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Monoamine oxidase A (MAO A) inhibitors decrease glioma progression

Monoamine oxidase A (MAO A) inhibitors decrease glioma progression

https://doi.org/10.18632/oncotarget.7283

Swati Kushal, Weijun Wang, Vijaya Pooja Vaikari, Rajesh Kota, Kevin Chen, Tzu-Shao Yeh, Niyati Jhaveri, Susan L. Groshen, Bogdan Z. Olenyuk, Thomas C. Chen, Florence M. Hofman,  and Jean C. Shih
13842-13853
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Withaferin-A suppress AKT induced tumor growth in colorectal cancer cells

Withaferin-A suppress AKT induced tumor growth in colorectal cancer cells

https://doi.org/10.18632/oncotarget.7351

Suman Suman, Trinath P. Das, Suman Sirimulla, Houda Alatassi, Murali K. Ankem,  and Chendil Damodaran
13854-13864
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GADD45α and γ interaction with CDK11p58 regulates SPDEF protein stability and SPDEF-mediated effects on cancer cell migration

GADD45α and γ interaction with CDK11p58 regulates SPDEF protein stability and SPDEF-mediated effects on cancer cell migration

https://doi.org/10.18632/oncotarget.7355

Rodrigo E. Tamura, Juliano D. Paccez, Kristal C. Duncan, Mirian G. Morale, Fernando M. Simabuco, Simon Dillon, Ricardo G. Correa, Xuesong Gu, Towia A. Libermann,  and Luiz F. Zerbini
13865-13879
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

A propensity score matching analysis of survival following segmentectomy or wedge resection in early-stage lung invasive adenocarcinoma or squamous cell carcinoma

A propensity score matching analysis of survival following segmentectomy or wedge resection in early-stage lung invasive adenocarcinoma or squamous cell carcinoma

https://doi.org/10.18632/oncotarget.7284

Yang Zhang, Yihua Sun,  and Haiquan Chen
13880-13885
Abstract  |  PDF  |  HTML  |  Order a Reprint

Prognostic and therapeutic role of targetable lesions in B-lineage acute lymphoblastic leukemia without recurrent fusion genes

Prognostic and therapeutic role of targetable lesions in B-lineage acute lymphoblastic leukemia without recurrent fusion genes

https://doi.org/10.18632/oncotarget.7356

Monica Messina, Sabina Chiaretti, Jiguang Wang, Anna Lucia Fedullo, Nadia Peragine, Valentina Gianfelici, Alfonso Piciocchi, Fulvia Brugnoletti, Filomena Di Giacomo, Simona Pauselli, Antony B. Holmes, Maria Cristina Puzzolo, Giulia Ceglie, Valerio Apicella, Marco Mancini, Geertruy te Kronnie, Anna Maria Testi, Antonella Vitale, Marco Vignetti, Anna Guarini, Raul Rabadan,  and Robin Foà
13886-13901
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Induction of methionine adenosyltransferase 2A in tamoxifen-resistant breast cancer cells

Induction of methionine adenosyltransferase 2A in tamoxifen-resistant breast cancer cells

https://doi.org/10.18632/oncotarget.5298

Nguyen Thi Thuy Phuong, Sang Kyum Kim, Ji Hye Im, Jin Won Yang, Min Chang Choi, Sung Chul Lim, Kwang Yeol Lee, Young Mi Kim, Jeong Hoon Yoon,  and Keon Wook Kang
13902-13916
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Acquisition of tumorigenic potential and enhancement of angiogenesis in pulmonary stem/progenitor cells through Oct-4 hyperexpression

Acquisition of tumorigenic potential and enhancement of angiogenesis in pulmonary stem/progenitor cells through Oct-4 hyperexpression

https://doi.org/10.18632/oncotarget.7285

Sing-Yi Gu, Choa-Chi Ho, Yung-Kang Huang, Huei-Wen Chen, Yu-Chi Wang, Chia-Yu Kuo, Shu-Chun Teng, Wen-Mei Fu, Pan-Chyr Yang, Cheng-Wen Wu, Fu-Chuo Peng,  and Thai-Yen Ling
13917-13931
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Osteoactivin (GPNMB) ectodomain protein promotes growth and invasive behavior of human lung cancer cells

Osteoactivin (GPNMB) ectodomain protein promotes growth and invasive behavior of human lung cancer cells

https://doi.org/10.18632/oncotarget.7323

Moses O. Oyewumi, Dharani Manickavasagam, Kimberly Novak, Daniel Wehrung, Nikola Paulic, Fouad M. Moussa, Gregory R. Sondag,  and Fayez F. Safadi
13932-13944
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Novel potential serological prostate cancer biomarkers using CT100+ cancer antigen microarray platform in a multi-cultural South African cohort

Novel potential serological prostate cancer biomarkers using CT100+ cancer antigen microarray platform in a multi-cultural South African cohort

https://doi.org/10.18632/oncotarget.7359

Henry A. Adeola, Muneerah Smith, Lisa Kaestner, Jonathan M. Blackburn,  and Luiz F. Zerbini
13945-13964
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Inhibition of the p53/hDM2 protein-protein interaction by cyclometallated iridium(III) compounds

Inhibition of the p53/hDM2 protein-protein interaction by cyclometallated iridium(III) compounds

https://doi.org/10.18632/oncotarget.7369

Li-Juan Liu, Bingyong He, Jennifer A. Miles, Wanhe Wang, Zhifeng Mao, Weng Ian Che, Jin-Jian Lu, Xiu-Ping Chen, Andrew J. Wilson, Dik-Lung Ma,  and Chung-Hang Leung
13965-13975
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Elevated expression of IFN-inducible CXCR3 ligands predicts poor prognosis in patients with non-metastatic clear-cell renal cell carcinoma

Elevated expression of IFN-inducible CXCR3 ligands predicts poor prognosis in patients with non-metastatic clear-cell renal cell carcinoma

https://doi.org/10.18632/oncotarget.7468

Weisi Liu, Yidong Liu, Qiang Fu, Lin Zhou, Yuan Chang, Le Xu, Weijuan Zhang,  and Jiejie Xu
13976-13983
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Analogs of the novel phytohormone, strigolactone, trigger apoptosis and synergize with PARP inhibitors by inducing DNA damage and inhibiting DNA repair

Analogs of the novel phytohormone, strigolactone, trigger apoptosis and synergize with PARP inhibitors by inducing DNA damage and inhibiting DNA repair

https://doi.org/10.18632/oncotarget.7414

Michael P. Croglio, Jefferson M. Haake, Colin P. Ryan, Victor S. Wang, Jennifer Lapier, Jamie P. Schlarbaum, Yaron Dayani, Emma Artuso, Cristina Prandi, Hinanit Koltai, Keli Agama, Yves Pommier, Yu Chen, Lucas Tricoli, Jeannine R. LaRocque, Christopher Albanese,  and Ronit I. Yarden
13984-14001
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Enhanced eryptosis contributes to anemia in lung cancer patients

Enhanced eryptosis contributes to anemia in lung cancer patients

https://doi.org/10.18632/oncotarget.7286

Rosi Bissinger, Carla Schumacher, Syed M. Qadri, Sabina Honisch, Abaid Malik, Friedrich Götz, Hans-Georg Kopp,  and Florian Lang
14002-14014
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Targeting endothelial connexin40 inhibits tumor growth by reducing angiogenesis and improving vessel perfusion

Targeting endothelial connexin40 inhibits tumor growth by reducing angiogenesis and improving vessel perfusion

https://doi.org/10.18632/oncotarget.7370

Florian Alonso, Sonia Domingos-Pereira, Loïc Le Gal, Laurent Derré, Paolo Meda, Patrice Jichlinski, Denise Nardelli-Haefliger,  and Jacques-Antoine Haefliger
14015-14028
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Involvement of calprotectin (S100A8/A9) in molecular pathways associated with HNSCC

Involvement of calprotectin (S100A8/A9) in molecular pathways associated with HNSCC

https://doi.org/10.18632/oncotarget.7373

Ali Khammanivong, Brent S. Sorenson, Karen F. Ross, Erin B. Dickerson, Rifat Hasina, Mark W. Lingen,  and Mark C. Herzberg
14029-14047
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Crosstalk between RON and androgen receptor signaling in the development of castration resistant prostate cancer

Crosstalk between RON and androgen receptor signaling in the development of castration resistant prostate cancer

https://doi.org/10.18632/oncotarget.7287

Izhar Batth, Huiyoung Yun, Suleman Hussain, Peng Meng, Pawel Osmulski, Tim Hui-Ming Huang, Roble Bedolla, Amanda Profit, Robert Reddick,  and Addanki Kumar
14048-14063
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Carcinoma-associated fucosylated antigens are markers of the epithelial state and can contribute to cell adhesion through CLEC17A (Prolectin)

Carcinoma-associated fucosylated antigens are markers of the epithelial state and can contribute to cell adhesion through CLEC17A (Prolectin)

https://doi.org/10.18632/oncotarget.7476

Adrien Breiman, María Dolores López Robles, Sophie de Carné Trécesson, Klara Echasserieau, Karine Bernardeau, Kurt Drickamer, Anne Imberty, Sophie Barillé-Nion, Frédéric Altare,  and Jacques Le Pendu
14064-14082
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Combining FoxP3 and Helios with GARP/LAP markers can identify expanded Treg subsets in cancer patients

Combining FoxP3 and Helios with GARP/LAP markers can identify expanded Treg subsets in cancer patients

https://doi.org/10.18632/oncotarget.7334

May Abd Al Samid, Belal Chaudhary, Yazan S. Khaled, Basil J. Ammori,  and Eyad Elkord
14083-14094
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Distinct features between MLH1-methylated and unmethylated colorectal carcinomas with the CpG island methylator phenotype: implications in the serrated neoplasia pathway

Distinct features between MLH1-methylated and unmethylated colorectal carcinomas with the CpG island methylator phenotype: implications in the serrated neoplasia pathway

https://doi.org/10.18632/oncotarget.7374

Jung Ho Kim, Jeong Mo Bae, Nam-Yun Cho,  and Gyeong Hoon Kang
14095-14111
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Expression of GADS enhances FLT3-induced mitogenic signaling

Expression of GADS enhances FLT3-induced mitogenic signaling

https://doi.org/10.18632/oncotarget.7415

Rohit A. Chougule, Eugenia Cordero, Sausan A. Moharram, Kristian Pietras, Lars Rönnstrand,  and Julhash U. Kazi
14112-14124
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The mannose receptor LY75 (DEC205/CD205) modulates cellular phenotype and metastatic potential of ovarian cancer cells

The mannose receptor LY75 (DEC205/CD205) modulates cellular phenotype and metastatic potential of ovarian cancer cells

https://doi.org/10.18632/oncotarget.7288

Adnen Faddaoui, Magdalena Bachvarova, Marie Plante, Jean Gregoire, Marie-Claude Renaud, Alexandra Sebastianelli, Stephane Gobeil, Chantale Morin, Elizabeth Macdonald, Barbara Vanderhyden,  and Dimcho Bachvarov
14125-14142
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Combination photoimmunotherapy with monoclonal antibodies recognizing different epitopes of human epidermal growth factor receptor 2: an assessment of phototherapeutic effect based on fluorescence molecular imaging

Combination photoimmunotherapy with monoclonal antibodies recognizing different epitopes of human epidermal growth factor receptor 2: an assessment of phototherapeutic effect based on fluorescence molecular imaging

https://doi.org/10.18632/oncotarget.7490

Kimihiro Ito, Makoto Mitsunaga, Takashi Nishimura, Hisataka Kobayashi,  and Hisao Tajiri
14143-14152
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Expression of androgen receptor in non-muscle-invasive bladder cancer predicts the preventive effect of androgen deprivation therapy on tumor recurrence

Expression of androgen receptor in non-muscle-invasive bladder cancer predicts the preventive effect of androgen deprivation therapy on tumor recurrence

https://doi.org/10.18632/oncotarget.7358

Koji Izumi, Yusuke Ito, Hiroshi Miyamoto, Yasuhide Miyoshi, Junichi Ota, Masatoshi Moriyama, Tetsuo Murai, Hiroyuki Hayashi, Yoshiaki Inayama, Kenichi Ohashi, Masahiro Yao,  and Hiroji Uemura
14153-14160
Abstract  |  PDF  |  HTML  |  Order a Reprint

Quantitative proteomics reveals the novel co-expression signatures in early brain development for prognosis of glioblastoma multiforme

Quantitative proteomics reveals the novel co-expression signatures in early brain development for prognosis of glioblastoma multiforme

https://doi.org/10.18632/oncotarget.7416

Xuexin Yu, Lin Feng, Dianming Liu, Lianfeng Zhang, Bo Wu, Wei Jiang, Zujing Han,  and Shujun Cheng
14161-14171
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Clinical implications of TP53 mutations in myelodysplastic syndromes treated with hypomethylating agents

Clinical implications of TP53 mutations in myelodysplastic syndromes treated with hypomethylating agents

https://doi.org/10.18632/oncotarget.7290

Koichi Takahashi, Keyur Patel, Carlos Bueso-Ramos, Jianhua Zhang, Curtis Gumbs, Elias Jabbour, Tapan Kadia, Michael Andreff, Marina Konopleva, Courtney DiNardo, Naval Daver, Jorge Cortes, Zeev Estrov, Andrew Futreal, Hagop Kantarjian,  and Guillermo Garcia-Manero
14172-14187
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

DEPTOR suppresses the progression of esophageal squamous cell carcinoma and predicts poor prognosis

DEPTOR suppresses the progression of esophageal squamous cell carcinoma and predicts poor prognosis

https://doi.org/10.18632/oncotarget.7420

Yan-Mei Ji, Xue-Feng Zhou, Jun Zhang, Xiang Zheng, Sheng-Bao Li, Zhi-Qiang Wei, Tao Liu, Dong-Liang Cheng, Ping Liu, Kuncheng Song, Tao Tan, Hua Zhu,  and Jia-Long Guo
14188-14198
Abstract  |  PDF  |  HTML  |  Order a Reprint

Synergic interaction between amyloid precursor protein and neural cell adhesion molecule promotes neurite outgrowth

Synergic interaction between amyloid precursor protein and neural cell adhesion molecule promotes neurite outgrowth

https://doi.org/10.18632/oncotarget.7348

Keping Chen, Huixia Lu, Tianli Gao, Xiulei Xue, Chunling Wang,  and Fengqin Miao
14199-14206
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Transcriptomic analysis of stage 1 versus advanced adult granulosa cell tumors

Transcriptomic analysis of stage 1 versus advanced adult granulosa cell tumors

https://doi.org/10.18632/oncotarget.7422

Maria Alexiadis, Simon Chu, Dilys Leung, Jodee A. Gould, Tom Jobling,  and Peter J. Fuller
14207-14219
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Longitudinal tracking of subpopulation dynamics and molecular changes during LNCaP cell castration and identification of inhibitors that could target the PSA−/lo castration-resistant cells

Longitudinal tracking of subpopulation dynamics and molecular changes during LNCaP cell castration and identification of inhibitors that could target the PSA−/lo castration-resistant cells

https://doi.org/10.18632/oncotarget.7303

Kiera Rycaj, Eun Jeong Cho, Xin Liu, Hsueh-Ping Chao, Bigang Liu, Qiuhui Li, Ashwini K. Devkota, Dingxiao Zhang, Xin Chen, John Moore, Kevin N. Dalby,  and Dean G. Tang
14220-14240
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Parabolic relationship between sex-specific serum high sensitive C reactive protein and non-alcoholic fatty liver disease in chinese adults: a large population-based study

Parabolic relationship between sex-specific serum high sensitive C reactive protein and non-alcoholic fatty liver disease in chinese adults: a large population-based study

https://doi.org/10.18632/oncotarget.7401

Li-Ren Wang, Wen-Yue Liu, Sheng-Jie Wu, Gui-Qi Zhu, Yi-Qian Lin, Martin Braddock, Dong-Chu Zhang,  and Ming-Hua Zheng
14241-14250
Abstract  |  PDF  |  HTML  |  Order a Reprint

Myeloid neoplasms with isolated isochromosome 17q demonstrate a high frequency of mutations in SETBP1, SRSF2, ASXL1 and NRAS

Myeloid neoplasms with isolated isochromosome 17q demonstrate a high frequency of mutations in SETBP1, SRSF2, ASXL1 and NRAS

https://doi.org/10.18632/oncotarget.7350

Rashmi Kanagal-Shamanna, Rajyalakshmi Luthra, Cameron C. Yin, Keyur P. Patel, Koichi Takahashi, Xinyan Lu, John Lee, Chong Zhao, Francesco Stingo, Zhuang Zuo, Mark J. Routbort, Rajesh R. Singh, Patricia Fox, Farhad Ravandi, Guillermo Garcia-Manero, L. Jeffrey Medeiros,  and Carlos E. Bueso-Ramos
14251-14258
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

BK K+ channel blockade inhibits radiation-induced migration/brain infiltration of glioblastoma cells

BK K+ channel blockade inhibits radiation-induced migration/brain infiltration of glioblastoma cells

https://doi.org/10.18632/oncotarget.7423

Lena Edalat, Benjamin Stegen, Lukas Klumpp, Erik Haehl, Karin Schilbach, Robert Lukowski, Matthias Kühnle, Günther Bernhardt, Armin Buschauer, Daniel Zips, Peter Ruth,  and Stephan M. Huber
14259-14278
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

The molecular and clinical verification of therapeutic resistance via the p38 MAPK–Hsp27 axis in lung cancer

The molecular and clinical verification of therapeutic resistance via the p38 MAPK–Hsp27 axis in lung cancer

https://doi.org/10.18632/oncotarget.7306

Chia-Lin Liu, Su-Feng Chen, Min-Zu Wu, Shu-Wen Jao, Yaoh-Shiang Lin, Chin-Yuh Yang, Tsai-Yu Lee, Lian-Wu Wen, Guo-Lun Lan,  and Shin Nieh
14279-14290
Abstract  |  PDF  |  HTML  |  Order a Reprint

The significance of phosphorylated heat shock protein 27 on the prognosis of pancreatic cancer

The significance of phosphorylated heat shock protein 27 on the prognosis of pancreatic cancer

https://doi.org/10.18632/oncotarget.7424

Mitsuru Okuno, Ichiro Yasuda, Seiji Adachi, Masanori Nakashima, Junji Kawaguchi, Shinpei Doi, Takuji Iwashita, Yoshinobu Hirose, Osamu Kozawa, Naoki Yoshimi, Masahito Shimizu,  and Hisataka Moriwaki
14291-14299
Abstract  |  PDF  |  HTML  |  Order a Reprint

RACK1 overexpression is linked to acquired imatinib resistance in gastrointestinal stromal tumor

RACK1 overexpression is linked to acquired imatinib resistance in gastrointestinal stromal tumor

https://doi.org/10.18632/oncotarget.7426

Xiaodong Gao, Anwei Xue, Yong Fang, Ping Shu, Jiaqian Ling, Yingyong Hou, Kuntang Shen, Jing Qin, Yihong Sun,  and Xinyu Qin
14300-14309
Abstract  |  PDF  |  HTML  |  Order a Reprint

Overexpression of TSC-22 (transforming growth factor- β-stimulated clone-22) causes marked obesity, splenic abnormality and B cell lymphoma in transgenic mice

Overexpression of TSC-22 (transforming growth factor- β-stimulated clone-22) causes marked obesity, splenic abnormality and B cell lymphoma in transgenic mice

https://doi.org/10.18632/oncotarget.7308

Daisuke Uchida, Hitoshi Kawamata, Fumie Omotehara, Yoshihiro Miwa, Hideki Horiuchi, Tadashi Furihata, Masatsugu Tachibana,  and Takahiro Fujimori
14310-14323
Abstract  |  PDF  |  HTML  |  Order a Reprint

Comparative effectiveness of light emitting diodes (LEDs) and Lasers in near infrared photoimmunotherapy

Comparative effectiveness of light emitting diodes (LEDs) and Lasers in near infrared photoimmunotherapy

https://doi.org/10.18632/oncotarget.7365

Kazuhide Sato, Rira Watanabe, Hirofumi Hanaoka, Takahito Nakajima, Peter L. Choyke,  and Hisataka Kobayashi
14324-14335
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Zinc finger protein ZBTB20 is an independent prognostic marker and promotes tumor growth of human hepatocellular carcinoma by repressing FoxO1

Zinc finger protein ZBTB20 is an independent prognostic marker and promotes tumor growth of human hepatocellular carcinoma by repressing FoxO1

https://doi.org/10.18632/oncotarget.7425

Heping Kan, Yuqi Huang, Xianghong Li, Dingli Liu, Jianjia Chen,  and Miaojiang Shu
14336-14349
Abstract  |  PDF  |  HTML  |  Order a Reprint

Hedgehog inhibitors selectively target cell migration and adhesion of mantle cell lymphoma in bone marrow microenvironment

Hedgehog inhibitors selectively target cell migration and adhesion of mantle cell lymphoma in bone marrow microenvironment

https://doi.org/10.18632/oncotarget.7320

Han Zhang, Zheng Chen, Sattva S. Neelapu, Jorge Romaguera,  and Nami McCarty
14350-14365
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

SIRT1 at the crossroads of AKT1 and ERβ in malignant pleural mesothelioma cells

SIRT1 at the crossroads of AKT1 and ERβ in malignant pleural mesothelioma cells

https://doi.org/10.18632/oncotarget.7321

Giulia Pinton, Sara Zonca, Arcangela G. Manente, Maria Cavaletto, Ester Borroni, Antonio Daga, Puthen V. Jithesh, Dean Fennell, Stefan Nilsson,  and Laura Moro
14366-14379
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

The essential role of methylthioadenosine phosphorylase in prostate cancer

The essential role of methylthioadenosine phosphorylase in prostate cancer

https://doi.org/10.18632/oncotarget.7486

Gaia Bistulfi, Hayley C. Affronti, Barbara A. Foster, Ellen Karasik, Bryan Gillard, Carl Morrison, James Mohler, James G. Phillips,  and Dominic J. Smiraglia
14380-14393
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Retrospective study testing next generation sequencing of selected cancer-associated genes in resected prostate cancer

Retrospective study testing next generation sequencing of selected cancer-associated genes in resected prostate cancer

https://doi.org/10.18632/oncotarget.7343

Marco Lo Iacono, Consuelo Buttigliero, Valentina Monica, Enrico Bollito, Diletta Garrou, Susanna Cappia, Ida Rapa, Francesca Vignani, Valentina Bertaglia, Cristian Fiori, Mauro Papotti, Marco Volante, Giorgio V. Scagliotti, Francesco Porpiglia,  and Marcello Tucci
14394-14404
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

An alternatively spliced variant of CXCR3 mediates the metastasis of CD133+ liver cancer cells induced by CXCL9

An alternatively spliced variant of CXCR3 mediates the metastasis of CD133+ liver cancer cells induced by CXCL9

https://doi.org/10.18632/oncotarget.7360

Qiang Ding, Yujia Xia, Shuping Ding, Panpan Lu, Liang Sun,  and Mei Liu
14405-14414
Abstract  |  PDF  |  HTML  |  Order a Reprint

Cross-platform comparison of independent datasets identifies an immune signature associated with improved survival in metastatic melanoma

Cross-platform comparison of independent datasets identifies an immune signature associated with improved survival in metastatic melanoma

https://doi.org/10.18632/oncotarget.7361

Ricardo D. Lardone, Seema B. Plaisier, Marian S. Navarrete, Jaime M. Shamonki, John R. Jalas, Peter A. Sieling,  and Delphine J. Lee
14415-14428
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

HULC long noncoding RNA silencing suppresses angiogenesis by regulating ESM-1 via the PI3K/Akt/mTOR signaling pathway in human gliomas

HULC long noncoding RNA silencing suppresses angiogenesis by regulating ESM-1 via the PI3K/Akt/mTOR signaling pathway in human gliomas

https://doi.org/10.18632/oncotarget.7418

Yu Zhu, Xuebin Zhang, Lisha Qi, Ying Cai, Ping Yang, Geng Xuan,  and Yuan Jiang
14429-14440
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Ubiquitin-specific protease 11 functions as a tumor suppressor by modulating Mgl-1 protein to regulate cancer cell growth

Ubiquitin-specific protease 11 functions as a tumor suppressor by modulating Mgl-1 protein to regulate cancer cell growth

https://doi.org/10.18632/oncotarget.7581

Key-Hwan Lim, Bharathi Suresh, Jung-Hyun Park, Young-Soo Kim, Suresh Ramakrishna,  and Kwang-Hyun Baek
14441-14457
Abstract  |  PDF  |  HTML  |  Order a Reprint

Inhibition of WIP1 phosphatase sensitizes breast cancer cells to genotoxic stress and to MDM2 antagonist nutlin-3

Inhibition of WIP1 phosphatase sensitizes breast cancer cells to genotoxic stress and to MDM2 antagonist nutlin-3

https://doi.org/10.18632/oncotarget.7363

Sona Pechackova, Kamila Burdova, Jan Benada, Petra Kleiblova, Gabriela Jenikova,  and Libor Macurek
14458-14475
Abstract  |  PDF  |  HTML  |  Order a Reprint

MeCP2 suppresses LIN28A expression via binding to its methylated-CpG islands in pancreatic cancer cells

MeCP2 suppresses LIN28A expression via binding to its methylated-CpG islands in pancreatic cancer cells

https://doi.org/10.18632/oncotarget.7507

Min Xu, Shihui Bian, Jie Li, Junbo He, Hui Chen, Lu Ge, Zhijun Jiao, Youli Zhang, Wanxin Peng, Fengyi Du, Yinyuan Mo,  and Aihua Gong
14476-14485
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Identification of a long non-coding RNA NR_026689 associated with lung carcinogenesis induced by NNK

Identification of a long non-coding RNA NR_026689 associated with lung carcinogenesis induced by NNK

https://doi.org/10.18632/oncotarget.7475

Jianjun Wu, Xun Li, Yiqin Xu, Ti Yang, Qiaoyuan Yang, Chengfeng Yang,  and Yiguo Jiang
14486-14498
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Characterization of novel low passage primary and metastatic colorectal cancer cell lines

Characterization of novel low passage primary and metastatic colorectal cancer cell lines

https://doi.org/10.18632/oncotarget.7391

Arnoud Boot, Jaap van Eendenburg, Stijn Crobach, Dina Ruano, Frank Speetjens, Jan Calame, Jan Oosting, Hans Morreau,  and Tom van Wezel
14499-14509
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Role of erythropoietin in the angiogenic activity of bone marrow endothelial cells of MGUS and multiple myeloma patients

Role of erythropoietin in the angiogenic activity of bone marrow endothelial cells of MGUS and multiple myeloma patients

https://doi.org/10.18632/oncotarget.7587

Aurelia Lamanuzzi, Ilaria Saltarella, Arianna Ferrucci, Roberto Ria, Simona Ruggieri, Vito Racanelli, Luigia Rao, Tiziana Annese, Beatrice Nico, Angelo Vacca,  and Domenico Ribatti
14510-14521
Abstract  |  PDF  |  HTML  |  Order a Reprint

Reduction of gastric cancer proliferation and invasion by miR-15a mediated suppression of Bmi-1 translation

Reduction of gastric cancer proliferation and invasion by miR-15a mediated suppression of Bmi-1 translation

https://doi.org/10.18632/oncotarget.7392

Changping Wu, Xiao Zheng, Xiaodong Li, Andrew Fesler, Wenwei Hu, Lujun Chen, Bin Xu, Qi Wang, Anthony Tong, Stephanie Burke, Jingfang Ju,  and Jingting Jiang
14522-14536
Abstract  |  PDF  |  HTML  |  Order a Reprint

X-linked FHL1 as a novel therapeutic target for head and neck squamous cell carcinoma

X-linked FHL1 as a novel therapeutic target for head and neck squamous cell carcinoma

https://doi.org/10.18632/oncotarget.7478

Wei Cao, Jiannan Liu, Ronghui Xia, Lu Lin, Xu Wang, Meng Xiao, Chenping Zhang, Jiang Li, Tong Ji,  and Wantao Chen
14537-14550
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Transcriptomic analysis of aggressive meningiomas identifies PTTG1 and LEPR as prognostic biomarkers independent of WHO grade

Transcriptomic analysis of aggressive meningiomas identifies PTTG1 and LEPR as prognostic biomarkers independent of WHO grade

https://doi.org/10.18632/oncotarget.7396

Melissa Schmidt, Andreas Mock, Christine Jungk, Felix Sahm, Anna Theresa Ull, Rolf Warta, Katrin Lamszus, Konstantinos Gousias, Ralf Ketter, Saskia Roesch, Carmen Rapp, Sebastian Schefzyk, Steffi Urbschat, Bernd Lahrmann, Almuth F. Kessler, Mario Löhr, Christian Senft, Niels Grabe, David Reuss, Philipp Beckhove, Manfred Westphal, Andreas von Deimling, Andreas Unterberg, Matthias Simon,  and Christel Herold-Mende
14551-14568
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

MicroRNA-410 acts as oncogene in NSCLC through downregulating SLC34A2 via activating Wnt/β-catenin pathway

MicroRNA-410 acts as oncogene in NSCLC through downregulating SLC34A2 via activating Wnt/β-catenin pathway

https://doi.org/10.18632/oncotarget.7538

Xuechao Zhang, Xixian Ke, Qiang Pu, Yue Yuan, Weihan Yang, Xinmei Luo, Qianqian Jiang, Xueting Hu, Yi Gong, Kui Tang, Xiaolan Su, Lunxu Liu, Wen Zhu,  and Yuquan Wei
14569-14585
Abstract  |  PDF  |  HTML  |  Order a Reprint

MST3 promotes proliferation and tumorigenicity through the VAV2/Rac1 signal axis in breast cancer

MST3 promotes proliferation and tumorigenicity through the VAV2/Rac1 signal axis in breast cancer

https://doi.org/10.18632/oncotarget.7542

Chien-Yu Cho, Kuo-Ting Lee, Wei-Ching Chen, Chih-Yang Wang, Yung-Sheng Chang, Hau-Lun Huang, Hui-Ping Hsu, Meng-Chi Yen, Ming-Zong Lai,  and Ming-Derg Lai
14586-14604
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Assessment of cholecystokinin 2 receptor (CCK2R) in neoplastic tissue

Assessment of cholecystokinin 2 receptor (CCK2R) in neoplastic tissue

https://doi.org/10.18632/oncotarget.7522

Jyoti Roy, Karson S. Putt, Domenico Coppola, Marino E. Leon, Farah K. Khalil, Barbara A. Centeno, Noel Clark, Valerie E. Stark, David L. Morse,  and Philip S. Low
14605-14615
Abstract  |  PDF  |  HTML  |  Order a Reprint

Bakuchiol suppresses proliferation of skin cancer cells by directly targeting Hck, Blk, and p38 MAP kinase

Bakuchiol suppresses proliferation of skin cancer cells by directly targeting Hck, Blk, and p38 MAP kinase

https://doi.org/10.18632/oncotarget.7524

Jong-Eun Kim, Jae Hwan Kim, Younghyun Lee, Hee Yang, Yong-Seok Heo, Ann M. Bode, Ki Won Lee,  and Zigang Dong
14616-14627
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

AB209630, a long non-coding RNA decreased expression in hypopharyngeal squamous cell carcinoma, influences proliferation, invasion, metastasis, and survival

AB209630, a long non-coding RNA decreased expression in hypopharyngeal squamous cell carcinoma, influences proliferation, invasion, metastasis, and survival

https://doi.org/10.18632/oncotarget.7403

Jieyu Zhou, Maocai Li, Wenbin Yu, Wenming Li, Juan Wang, Xuan Xiang, Guojun Li, Xinliang Pan,  and Dapeng Lei
14628-14638
Abstract  |  PDF  |  HTML  |  Order a Reprint

Exosomes confer pro-survival signals to alter the phenotype of prostate cells in their surrounding environment

Exosomes confer pro-survival signals to alter the phenotype of prostate cells in their surrounding environment

https://doi.org/10.18632/oncotarget.7052

Elham Hosseini-Beheshti, Wendy Choi, Louis-Bastien Weiswald, Geetanjali Kharmate, Mazyar Ghaffari, Mani Roshan-Moniri, Mohamed D. Hassona, Leslie Chan, Mei Yieng Chin, Isabella T. Tai, Paul S. Rennie, Ladan Fazli,  and Emma S. Tomlinson Guns
14639-14658
Abstract  |  PDF  |  HTML  |  Order a Reprint

Nrf2 is the key to chemotherapy resistance in MCF7 breast cancer cells under hypoxia

Nrf2 is the key to chemotherapy resistance in MCF7 breast cancer cells under hypoxia

https://doi.org/10.18632/oncotarget.7406

Jhih-Pu Syu, Jen-Tsan Chi,  and Hsiu-Ni Kung
14659-14672
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

MPC1, a key gene in cancer metabolism, is regulated by COUPTFII in human prostate cancer

MPC1, a key gene in cancer metabolism, is regulated by COUPTFII in human prostate cancer

https://doi.org/10.18632/oncotarget.7405

Leiming Wang, Mafei Xu, Jun Qin, Shih-Chieh Lin, Hui-Ju Lee, Sophia Y. Tsai,  and Ming-Jer Tsai
14673-14683
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Use of integrin alpha 6 transcripts in a stool mRNA assay for the detection of colorectal cancers at curable stages

Use of integrin alpha 6 transcripts in a stool mRNA assay for the detection of colorectal cancers at curable stages

https://doi.org/10.18632/oncotarget.7407

Jean-François Beaulieu, Elizabeth Herring, Shigeru Kanaoka,  and Éric Tremblay
14684-14692
Abstract  |  PDF  |  HTML  |  Order a Reprint

Obatoclax impairs lysosomal function to block autophagy in cisplatin-sensitive and -resistant esophageal cancer cells

Obatoclax impairs lysosomal function to block autophagy in cisplatin-sensitive and -resistant esophageal cancer cells

https://doi.org/10.18632/oncotarget.7492

Le Yu, William K.K. Wu, Chunping Gu, Desheng Zhong, Xuyan Zhao, Yi Kong, Qinghuan Lin, Matthew T.V. Chan, Zhitao Zhou,  and Shuwen Liu
14693-14707
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

The cancer-testis antigens SPANX-A/C/D and CTAG2 promote breast cancer invasion

The cancer-testis antigens SPANX-A/C/D and CTAG2 promote breast cancer invasion

https://doi.org/10.18632/oncotarget.7408

Erin A. Maine, Jill M. Westcott, Amanda M. Prechtl, Tuyen T. Dang, Angelique W. Whitehurst,  and Gray W. Pearson
14708-14726
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Therapeutic siRNA for drug-resistant HER2-positive breast cancer

Therapeutic siRNA for drug-resistant HER2-positive breast cancer

https://doi.org/10.18632/oncotarget.7409

Shenda Gu, Zhi Hu, Worapol Ngamcherdtrakul, David J. Castro, Jingga Morry, Moataz M. Reda, Joe W. Gray,  and Wassana Yantasee
14727-14741
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

A20 inhibits the motility of HCC cells induced by TNF-α

A20 inhibits the motility of HCC cells induced by TNF-α

https://doi.org/10.18632/oncotarget.7521

Xianteng Wang, Chao Ma, Zhaoyun Zong, Ying Xiao, Na Li, Chun Guo, Lining Zhang,  and Yongyu Shi
14742-14754
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

A predictive nomogram improved diagnostic accuracy and interobserver agreement of perirectal lymph nodes metastases in rectal cancer

A predictive nomogram improved diagnostic accuracy and interobserver agreement of perirectal lymph nodes metastases in rectal cancer

https://doi.org/10.18632/oncotarget.7548

Yongfeng Liu, Renjie Wang, Ying Ding, Shanshan Tu, Yi Liu, Youcun Qian, Linghui Xu, Tong Tong, Sanjun Cai,  and Junjie Peng
14755-14764
Abstract  |  PDF  |  HTML  |  Order a Reprint

The lectin-like oxidized LDL receptor-1: a new potential molecular target in colorectal cancer

The lectin-like oxidized LDL receptor-1: a new potential molecular target in colorectal cancer

https://doi.org/10.18632/oncotarget.7430

Michela Murdocca, Ruggiero Mango, Sabina Pucci, Silvia Biocca, Barbara Testa, Rosamaria Capuano, Roberto Paolesse, Massimo Sanchez, Augusto Orlandi, Corrado di Natale, Giuseppe Novelli,  and Federica Sangiuolo
14765-14780
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Tumoral indoleamine 2, 3-dioxygenase 1 is regulated by monocytes and T lymphocytes collaboration in hepatocellular carcinoma

Tumoral indoleamine 2, 3-dioxygenase 1 is regulated by monocytes and T lymphocytes collaboration in hepatocellular carcinoma

https://doi.org/10.18632/oncotarget.7438

Qiyi Zhao, Pei-pei Wang, Zhan-lian Huang, Liang Peng, Chaoshuang Lin, Zhiliang Gao,  and Shicheng Su
14781-14790
Abstract  |  PDF  |  HTML  |  Order a Reprint

A novel miR-34a target, protein kinase D1, stimulates cancer stemness and drug resistance through GSK3/β-catenin signaling in breast cancer

A novel miR-34a target, protein kinase D1, stimulates cancer stemness and drug resistance through GSK3/β-catenin signaling in breast cancer

https://doi.org/10.18632/oncotarget.7443

Do Yeon Kim, Eun Young Park, EunSun Chang, Hyeok-Gu Kang, Yoonjin Koo, Eun Ji Lee, Je Yeong Ko, Hyun Kyung Kong, Kyung-Hee Chun,  and Jong Hoon Park
14791-14802
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

The CDK4/6 inhibitor LY2835219 has potent activity in combination with mTOR inhibitor in head and neck squamous cell carcinoma

The CDK4/6 inhibitor LY2835219 has potent activity in combination with mTOR inhibitor in head and neck squamous cell carcinoma

https://doi.org/10.18632/oncotarget.7543

Bo Mi Ku, Seong Yoon Yi, Jiae Koh, Yeon-Hee Bae, Jong-Mu Sun, Se-hoon Lee, Jin Seok Ahn, Keunchil Park,  and Myung-Ju Ahn
14803-14813
Abstract  |  PDF  |  HTML  |  Order a Reprint

Distinct lncRNA transcriptional fingerprints characterize progressive stages of multiple myeloma

Distinct lncRNA transcriptional fingerprints characterize progressive stages of multiple myeloma

https://doi.org/10.18632/oncotarget.7442

Domenica Ronchetti, Luca Agnelli, Elisa Taiana, Serena Galletti, Martina Manzoni, Katia Todoerti, Pellegrino Musto, Francesco Strozzi,  and Antonino Neri
14814-14830
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

CIP2A down regulation enhances the sensitivity of pancreatic cancer cells to gemcitabine

CIP2A down regulation enhances the sensitivity of pancreatic cancer cells to gemcitabine

https://doi.org/10.18632/oncotarget.7447

Peng Xu, Jie Yao, Jin He, Long Zhao, Xiaodong Wang, Zhennan Li,  and Jianjun Qian
14831-14840
Abstract  |  PDF  |  HTML  |  Order a Reprint

Development of a novel HAC-based “gain of signal” quantitative assay for measuring chromosome instability (CIN) in cancer cells

Development of a novel HAC-based “gain of signal” quantitative assay for measuring chromosome instability (CIN) in cancer cells

https://doi.org/10.18632/oncotarget.7854

Jung-Hyun Kim, Hee-Sheung Lee, Nicholas C. O. Lee, Nikolay V. Goncharov, Vadim Kumeiko, Hiroshi Masumoto, William C. Earnshaw, Natalay Kouprina,  and Vladimir Larionov
14841-14856
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Integrated quantitative proteomic and transcriptomic analysis of lung tumor and control tissue: a lung cancer showcase

Integrated quantitative proteomic and transcriptomic analysis of lung tumor and control tissue: a lung cancer showcase

https://doi.org/10.18632/oncotarget.7562

Stefan Tenzer, Petra Leidinger, Christina Backes, Hanno Huwer, Andreas Hildebrandt, Hans-Peter Lenhof, Tanja Wesse, Andre Franke, Eckart Meese,  and Andreas Keller
14857-14870
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Tumor necrosis factor-α and interferon-γ stimulate MUC16 (CA125) expression in breast, endometrial and ovarian cancers through NFκB

Tumor necrosis factor-α and interferon-γ stimulate MUC16 (CA125) expression in breast, endometrial and ovarian cancers through NFκB

https://doi.org/10.18632/oncotarget.7652

Micaela Morgado, Margie N. Sutton, Mary Simmons, Curtis R. Warren, Zhen Lu, Pamela E. Constantinou, Jinsong Liu, Lewis LW. Francis, R. Steven Conlan, Robert C. Bast Jr.,  and Daniel D. Carson
14871-14884
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Glucose-regulated protein 94 deficiency induces squamous cell metaplasia and suppresses PTEN-null driven endometrial epithelial tumor development

Glucose-regulated protein 94 deficiency induces squamous cell metaplasia and suppresses PTEN-null driven endometrial epithelial tumor development

https://doi.org/10.18632/oncotarget.7450

Jieli Shen, Lijing Yao, Yvonne G. Lin, Francesco J. DeMayo, John P. Lydon, Louis Dubeau,  and Amy S. Lee
14885-14897
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

APG101 efficiently rescues erythropoiesis in lower risk myelodysplastic syndromes with severe impairment of hematopoiesis

APG101 efficiently rescues erythropoiesis in lower risk myelodysplastic syndromes with severe impairment of hematopoiesis

https://doi.org/10.18632/oncotarget.7469

Anna Raimbault, Cecile Pierre-Eugene, Alexandra Rouquette, Celine Deudon, Lise Willems, Nicolas Chapuis, Stephanie Mathis, Claudia Kunz, Harald Fricke, Olivier Kosmider, Valerie Bardet, Michaela Fontenay,  and on behalf of the Groupe Francophone des Myélodysplasies
14898-14911
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

MicroRNA-323-3p inhibits cell invasion and metastasis in pancreatic ductal adenocarcinoma via direct suppression of SMAD2 and SMAD3

MicroRNA-323-3p inhibits cell invasion and metastasis in pancreatic ductal adenocarcinoma via direct suppression of SMAD2 and SMAD3

https://doi.org/10.18632/oncotarget.7482

Chunyou Wang, Pian Liu, Heshui Wu, Pengfei Cui, Yongfeng Li, Yao Liu, Zhiqiang Liu,  and Shanmiao Gou
14912-14924
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Telomere targeting with a novel G-quadruplex-interactive ligand BRACO-19 induces T-loop disassembly and telomerase displacement in human glioblastoma cells

Telomere targeting with a novel G-quadruplex-interactive ligand BRACO-19 induces T-loop disassembly and telomerase displacement in human glioblastoma cells

https://doi.org/10.18632/oncotarget.7483

Guangtong Zhou, Xinrui Liu, Yunqian Li, Songbai Xu, Chengyuan Ma, Xinmin Wu, Ye Cheng, Zhiyun Yu, Gang Zhao,  and Yong Chen
14925-14939
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Salmonella VNP20009-mediated RNA interference of ABCB5 moderated chemoresistance of melanoma stem cell and suppressed tumor growth more potently

Salmonella VNP20009-mediated RNA interference of ABCB5 moderated chemoresistance of melanoma stem cell and suppressed tumor growth more potently

https://doi.org/10.18632/oncotarget.7496

Xiaoxin Zhang, Xiawei Cheng, Yueyang Lai, Yuqiang Zhou, Wenmin Cao,  and Zi-Chun Hua
14940-14950
Abstract  |  PDF  |  HTML  |  Order a Reprint

The BMP inhibitor DAND5 in serum predicts poor survival in breast cancer

The BMP inhibitor DAND5 in serum predicts poor survival in breast cancer

https://doi.org/10.18632/oncotarget.7498

Yayun Chi, Ling Yao, Xin Hu, Sheng Huang, Naisi Huang, Shan Li, Zhiming Shao,  and Jiong Wu
14951-14962
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Primary tumor inflammation in gross tumor volume as a prognostic factor for nasopharyngeal carcinoma patients

Primary tumor inflammation in gross tumor volume as a prognostic factor for nasopharyngeal carcinoma patients

https://doi.org/10.18632/oncotarget.7699

Hao Peng, Lei Chen, Ling-Long Tang, Yuan Zhang, Wen-Fei Li, Yan-Ping Mao, Fan Zhang, Rui Guo, Li-Zhi Liu, Li Tian, Ai-Hua Lin, Ying Sun,  and Jun Ma
14963-14972
Abstract  |  PDF  |  HTML  |  Order a Reprint

Prognostic value of wait time in nasopharyngeal carcinoma treated with intensity modulated radiotherapy: a propensity matched analysis

Prognostic value of wait time in nasopharyngeal carcinoma treated with intensity modulated radiotherapy: a propensity matched analysis

https://doi.org/10.18632/oncotarget.7789

Yu-Pei Chen, Yan-Ping Mao, Wen-Na Zhang, Lei Chen, Ling-Long Tang, Wen-Fei Li, Xu Liu, Guan-Qun Zhou, Rui Guo, Ying Sun, Tie-Bang Kang, Mu-Sheng Zeng,  and Jun Ma
14973-14982
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Immunogenomics reveal molecular circuits of diclofenac induced liver injury in mice

Immunogenomics reveal molecular circuits of diclofenac induced liver injury in mice

https://doi.org/10.18632/oncotarget.7698

Eun-Hee Lee, Jung-Hwa Oh, Saravanakumar Selvaraj, Se-Myo Park, Mi-Sun Choi, Reinhard Spanel, Seokjoo Yoon,  and Jürgen Borlak
14983-15017
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Cilengitide in newly diagnosed glioblastoma: biomarker expression and outcome

Cilengitide in newly diagnosed glioblastoma: biomarker expression and outcome

https://doi.org/10.18632/oncotarget.7588

Michael Weller, Louis Burt Nabors, Thierry Gorlia, Henning Leske, Elisabeth Rushing, Pierre Bady, Christine Hicking, James Perry, Yong-Kil Hong, Patrick Roth, Wolfgang Wick, Simon L. Goodman, Monika E. Hegi, Martin Picard, Holger Moch, Josef Straub,  and Roger Stupp
15018-15032
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

The prevalence and clinicopathological features of programmed death-ligand 1 (PD-L1) expression: a pooled analysis of literatures

The prevalence and clinicopathological features of programmed death-ligand 1 (PD-L1) expression: a pooled analysis of literatures

https://doi.org/10.18632/oncotarget.7590

Ziying Lin, Yutong Xu, Yaxiong Zhang, Qihua He, Jianrong Zhang, Jianxing He,  and Wenhua Liang
15033-15046
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Fatty acid amide hydrolase inhibitors confer anti-invasive and antimetastatic effects on lung cancer cells

Fatty acid amide hydrolase inhibitors confer anti-invasive and antimetastatic effects on lung cancer cells

https://doi.org/10.18632/oncotarget.7592

Katrin Winkler, Robert Ramer, Sophie Dithmer, Igor Ivanov, Jutta Merkord,  and Burkhard Hinz
15047-15064
Abstract  |  PDF  |  HTML  |  Order a Reprint

Gene expression analyses of primary melanomas reveal CTHRC1 as an important player in melanoma progression

Gene expression analyses of primary melanomas reveal CTHRC1 as an important player in melanoma progression

https://doi.org/10.18632/oncotarget.7604

Johanna Eriksson, Vadim Le Joncour, Pirjo Nummela, Tiina Jahkola, Susanna Virolainen, Pirjo Laakkonen, Olli Saksela,  and Erkki Hölttä
15065-15092
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Therapeutic evaluation of microRNA-15a and microRNA-16 in ovarian cancer

Therapeutic evaluation of microRNA-15a and microRNA-16 in ovarian cancer

https://doi.org/10.18632/oncotarget.7618

Shailendra Kumar Dhar Dwivedi, Soumyajit Banerjee Mustafi, Lingegowda S. Mangala, Dahai Jiang, Sunila Pradeep, Cristian Rodriguez-Aguayo, Hui Ling, Cristina Ivan, Priyabrata Mukherjee, George A. Calin, Gabriel Lopez- Berestein, Anil K. Sood,  and Resham Bhattacharya`
15093-15104
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Effect of alpha-lipoic acid on radiation-induced small intestine injury in mice

Effect of alpha-lipoic acid on radiation-induced small intestine injury in mice

https://doi.org/10.18632/oncotarget.7874

Bae Kwon Jeong, Jin Ho Song, Hojin Jeong, Hoon Sik Choi, Jung Hwa Jung, Jong Ryeal Hahm, Seung Hoon Woo, Myeong Hee Jung, Bong-Hoi Choi, Jin Hyun Kim,  and Ki Mun Kang
15105-15117
Abstract  |  PDF  |  HTML  |  Order a Reprint

FGFR1 promotes the stem cell-like phenotype of FGFR1-amplified non-small cell lung cancer cells through the Hedgehog pathway

FGFR1 promotes the stem cell-like phenotype of FGFR1-amplified non-small cell lung cancer cells through the Hedgehog pathway

https://doi.org/10.18632/oncotarget.7701

Wenxiang Ji, Yongfeng Yu, Ziming Li, Guan Wang, Fan Li, Weiliang Xia,  and Shun Lu
15118-15134
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

P300 acetyltransferase regulates fatty acid synthase expression, lipid metabolism and prostate cancer growth

P300 acetyltransferase regulates fatty acid synthase expression, lipid metabolism and prostate cancer growth

https://doi.org/10.18632/oncotarget.7715

Xiaokun Gang, Yinhui Yang, Jian Zhong, Kui Jiang, Yunqian Pan, Jeffrey R. Karnes, Jun Zhang, Wanhai Xu, Guixia Wang,  and Haojie Huang
15135-15149
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

An increase in galectin-3 causes cellular unresponsiveness to IFN-γ-induced signal transduction and growth inhibition in gastric cancer cells

An increase in galectin-3 causes cellular unresponsiveness to IFN-γ-induced signal transduction and growth inhibition in gastric cancer cells

https://doi.org/10.18632/oncotarget.7750

Po-Chun Tseng, Chia-Ling Chen, Yan-Shen Shan,  and Chiou-Feng Lin
15150-15160
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

UBE2T promotes nasopharyngeal carcinoma cell proliferation, invasion, and metastasis by activating the AKT/GSK3β/β-catenin pathway

UBE2T promotes nasopharyngeal carcinoma cell proliferation, invasion, and metastasis by activating the AKT/GSK3β/β-catenin pathway

https://doi.org/10.18632/oncotarget.7805

Wei Hu, Lushan Xiao, Chuanhui Cao, Shengni Hua,  and Dehua Wu
15161-15172
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

MiR-26a and miR-144 inhibit proliferation and metastasis of esophageal squamous cell cancer by inhibiting cyclooxygenase-2

MiR-26a and miR-144 inhibit proliferation and metastasis of esophageal squamous cell cancer by inhibiting cyclooxygenase-2

https://doi.org/10.18632/oncotarget.7908

Ying Shao, Peng Li, Sheng-Tao Zhu, Ji-Ping Yue, Xiao-Jun Ji, Dan Ma, Li Wang, Yong-Jun Wang, Ye Zong, Yong-Dong Wu,  and Shu-Tian Zhang
15173-15186
Abstract  |  PDF  |  HTML  |  Order a Reprint

Down-regulation of osteoprotegerin expression as a novel biomarker for colorectal carcinoma

Down-regulation of osteoprotegerin expression as a novel biomarker for colorectal carcinoma

https://doi.org/10.18632/oncotarget.7885

Hyun-Soo Kim, Gun Yoon, Sung-Im Do, Sung-Joo Kim,  and Youn-Wha Kim
15187-15199
Abstract  |  PDF  |  HTML  |  Order a Reprint

Hypotaurine evokes a malignant phenotype in glioma through aberrant hypoxic signaling

Hypotaurine evokes a malignant phenotype in glioma through aberrant hypoxic signaling

https://doi.org/10.18632/oncotarget.7710

Peng Gao, Chunzhang Yang, Cody L. Nesvick, Michael J. Feldman, Saman Sizdahkhani, Huailei Liu, Huiying Chu, Fengxu Yang, Ling Tang, Jing Tian, Shiguang Zhao, Guohui Li, John D. Heiss, Yang Liu, Zhengping Zhuang,  and Guowang Xu
15200-15214
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Improved therapy for neuroblastoma using a combination approach: superior efficacy with vismodegib and topotecan

Improved therapy for neuroblastoma using a combination approach: superior efficacy with vismodegib and topotecan

https://doi.org/10.18632/oncotarget.7714

Nagendra K. Chaturvedi, Timothy R. McGuire, Don W. Coulter, Ashima Shukla, Erin M. McIntyre, John Graham Sharp,  and Shantaram S. Joshi
15215-15229
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Clinical Research Papers

Cervical cancer systemic inflammation score: a novel predictor of prognosis

Cervical cancer systemic inflammation score: a novel predictor of prognosis

https://doi.org/10.18632/oncotarget.7378

Ru-ru Zheng, Min Huang, Chu Jin, Han-chu Wang, Jiang-tao Yu, Lin-chai Zeng, Fei-yun Zheng,  and Feng Lin
15230-15242
Abstract  |  PDF  |  HTML  |  Order a Reprint

Early onset of hypertension and serum electrolyte changes as potential predictive factors of activity in advanced HCC patients treated with sorafenib: results from a retrospective analysis of the HCC-AVR group

Early onset of hypertension and serum electrolyte changes as potential predictive factors of activity in advanced HCC patients treated with sorafenib: results from a retrospective analysis of the HCC-AVR group

https://doi.org/10.18632/oncotarget.7444

Andrea Casadei Gardini, Emanuela Scarpi, Giorgia Marisi, Francesco Giuseppe Foschi, Gabriele Donati, Emanuela Giampalma, Luca Faloppi, Mario Scartozzi, Nicola Silvestris, Marcello Bisulli, Jody Corbelli, Andrea Gardini, Giuliano La Barba, Luigi Veneroni, Stefano Tamberi, Stefano Cascinu,  and Giovanni Luca Frassineti
15243-15251
Abstract  |  PDF  |  HTML  |  Order a Reprint

A new staging system for nasopharyngeal carcinoma based on intensity-modulated radiation therapy: results of a prospective multicentric clinical study

A new staging system for nasopharyngeal carcinoma based on intensity-modulated radiation therapy: results of a prospective multicentric clinical study

https://doi.org/10.18632/oncotarget.7553

Min Kang, Jianxiong Long, Guisheng Li, Haolin Yan, Guosheng Feng, Meilian Liu, Jinxian Zhu,  and Rensheng Wang
15252-15261
Abstract  |  PDF  |  HTML  |  Order a Reprint

The effect of neuraxial anesthesia on cancer recurrence and survival after cancer surgery: an updated meta-analysis

The effect of neuraxial anesthesia on cancer recurrence and survival after cancer surgery: an updated meta-analysis

https://doi.org/10.18632/oncotarget.7683

Meilin Weng, Wankun Chen, Wenting Hou, Lihong Li, Ming Ding,  and Changhong Miao
15262-15273
Abstract  |  PDF  |  HTML  |  Order a Reprint

The expression of plakoglobin is a potential prognostic biomarker for patients with surgically resected lung adenocarcinoma

The expression of plakoglobin is a potential prognostic biomarker for patients with surgically resected lung adenocarcinoma

https://doi.org/10.18632/oncotarget.7729

Xiaobo He, Ting Zhou, Guangwei Yang, Wenfeng Fang, Zelei Li, Jianhua Zhan, Yuanyuan Zhao, Zhibin Cheng, Yan Huang, Hongyun Zhao,  and Li Zhang
15274-15287
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint


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