Oncotarget

Vol 6, No 31

October 13, 2015

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Senescent stromal cells induce cancer cell migration via inhibition of RhoA/ROCK/myosin-based cell contractility. See Aifuwa et al.

Table of Contents

News

Autophagy manages disease-associated stress granules

Autophagy manages disease-associated stress granules

https://doi.org/10.18632/oncotarget.5902

Jin-A Lee
30421-30422
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Editorial

RIOK3 keeps MDA5 inactive

RIOK3 keeps MDA5 inactive

https://doi.org/10.18632/oncotarget.5265

Ken Takashima, Hiroyuki Oshiumi,  and Tsukasa Seya
30423-30424
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New tricks for KDEL receptors

New tricks for KDEL receptors

https://doi.org/10.18632/oncotarget.5444

Ming Yuan Li, Roberto Bruzzone,  and Pei Gang Wang
30425-30426
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Priming persistence of HCV

Priming persistence of HCV

https://doi.org/10.18632/oncotarget.5445

Anita Schuch, Robert Thimme,  and Maike Hofmann
30427-30428
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VDR and gemini ligands

VDR and gemini ligands

https://doi.org/10.18632/oncotarget.5446

Gilles Laverny,  and Daniel Metzger
30429-30430
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Deconvoluting AMPK dynamics

Deconvoluting AMPK dynamics

https://doi.org/10.18632/oncotarget.5447

Takafumi Miyamoto, Elmer Rho,  and Takanari Inoue
30431-30432
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Tension across adherens junctions: when less is more

Tension across adherens junctions: when less is more

https://doi.org/10.18632/oncotarget.5448

Kevin Kruse,  and Yulia A. Komarova
30433-30434
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PTX3 orchestrates tissue repair

PTX3 orchestrates tissue repair

https://doi.org/10.18632/oncotarget.5453

Andrea Doni, Cecilia Garlanda,  and Alberto Mantovani
30435-30436
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Passive virus movements with organelle dynamics

Passive virus movements with organelle dynamics

https://doi.org/10.18632/oncotarget.5897

Kazuya Ishikawa, Masayoshi Hashimoto,  and Shigetou Namba
30437-30438
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Architecture of viral replication factories

Architecture of viral replication factories

https://doi.org/10.18632/oncotarget.5900

Yongliang Zhang, Xiuling Cao,  and Dawei Li
30439-30440
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Cutaneous bacteria induce immunosuppression

Cutaneous bacteria induce immunosuppression

https://doi.org/10.18632/oncotarget.5962

Yuliya Skabytska,  and Tilo Biedermann
30441-30442
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Editorial: Chromosome

Lipase gene fusion: a new route to chronic pancreatitis

Lipase gene fusion: a new route to chronic pancreatitis

https://doi.org/10.18632/oncotarget.5454

Anders Molven, Pål R. Njølstad,  and Frank Ulrich Weiss
30443-30444
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Disconnect between EMT and metastasis in pancreas cancer

Disconnect between EMT and metastasis in pancreas cancer

https://doi.org/10.18632/oncotarget.5720

Martin C. Whittle,  and Sunil R. Hingorani
30445-30446
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Selective nuclear elimination in multinucleate cells

Selective nuclear elimination in multinucleate cells

https://doi.org/10.18632/oncotarget.5450

Daisuke Maruyama, Tomokazu Kawashima,  and Tetsuya Higashiyama
30447-30448
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Warm up and cool down!

Warm up and cool down!

https://doi.org/10.18632/oncotarget.5721

Tao Wang,  and Dengke Ma
30449-30450
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DOT1L: a new therapeutic target for aggressive breast cancer

DOT1L: a new therapeutic target for aggressive breast cancer

https://doi.org/10.18632/oncotarget.5860

Jeong-Yeon Lee,  and Gu Kong
30451-30452
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Priority Research Papers

Mitochondrial mass, a new metabolic biomarker for stem-like cancer cells: Understanding WNT/FGF-driven anabolic signaling

Mitochondrial mass, a new metabolic biomarker for stem-like cancer cells: Understanding WNT/FGF-driven anabolic signaling

https://doi.org/10.18632/oncotarget.5852

Rebecca Lamb, Gloria Bonuccelli, Béla Ozsvári, Maria Peiris-Pagès, Marco Fiorillo, Duncan L. Smith, Generoso Bevilacqua, Chiara Maria Mazzanti, Liam A. McDonnell, Antonio Giuseppe Naccarato, Maybo Chiu, Luke Wynne, Ubaldo E. Martinez-Outschoorn, Federica Sotgia,  and Michael P. Lisanti
30453-30471
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High mitochondrial mass identifies a sub-population of stem-like cancer cells that are chemo-resistant

High mitochondrial mass identifies a sub-population of stem-like cancer cells that are chemo-resistant

https://doi.org/10.18632/oncotarget.5401

Gillian Farnie, Federica Sotgia,  and Michael P. Lisanti
30472-30486
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Synergistic effects of p53 activation via MDM2 inhibition in combination with inhibition of Bcl-2 or Bcr-Abl in CD34+ proliferating and quiescent chronic myeloid leukemia blast crisis cells

Synergistic effects of p53 activation via MDM2 inhibition in combination with inhibition of Bcl-2 or Bcr-Abl in CD34+ proliferating and quiescent chronic myeloid leukemia blast crisis cells

https://doi.org/10.18632/oncotarget.5890

Bing Z. Carter, Po Yee Mak, Duncan H. Mak, Vivian R. Ruvolo, Wendy Schober, Teresa McQueen, Jorge Cortes, Hagop M. Kantarjian, Richard E. Champlin, Marina Konopleva,  and Michael Andreeff
30487-30499
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Induction of KIAA1199/CEMIP is associated with colon cancer phenotype and poor patient survival

Induction of KIAA1199/CEMIP is associated with colon cancer phenotype and poor patient survival

https://doi.org/10.18632/oncotarget.5921

Stephen P. Fink, Lois L. Myeroff, Revital Kariv, Petra Platzer, Baozhong Xin, Debra Mikkola, Earl Lawrence, Nathan Morris, Arman Nosrati, James K. V. Willson, Joseph Willis, Martina Veigl, Jill S. Barnholtz-Sloan, Zhenghe Wang,  and Sanford D. Markowitz
30500-30515
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Senescent stromal cells induce cancer cell migration via inhibition of RhoA/ROCK/myosin-based cell contractility

Senescent stromal cells induce cancer cell migration via inhibition of RhoA/ROCK/myosin-based cell contractility

https://doi.org/10.18632/oncotarget.5854

Ivie Aifuwa, Anjil Giri, Nick Longe, Sang Hyuk Lee, Steven S. An,  and Denis Wirtz
30516-30531
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Research Papers: Gerotarget (Focus on Aging)

The eye lens: age-related trends and individual variations in refractive index and shape parameters

The eye lens: age-related trends and individual variations in refractive index and shape parameters

https://doi.org/10.18632/oncotarget.5762

Barbara Pierscionek, Mehdi Bahrami, Masato Hoshino, Kentaro Uesugi, Justyn Regini,  and Naoto Yagi
30532-30544
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New insights into the impact of Lactobacillus population on host-bacteria metabolic interplay

New insights into the impact of Lactobacillus population on host-bacteria metabolic interplay

https://doi.org/10.18632/oncotarget.5906

Caroline I. Le Roy, Jelena Štšepetova, Epp Sepp, Epp Songisepp, Sandrine P. Claus,  and Marika Mikelsaar
30545-30556
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Length of paternal lifespan is manifested in the DNA methylome of their nonagenarian progeny

Length of paternal lifespan is manifested in the DNA methylome of their nonagenarian progeny

https://doi.org/10.18632/oncotarget.5905

Saara Marttila, Laura Kananen, Juulia Jylhävä, Tapio Nevalainen, Antti Hervonen, Marja Jylhä,  and Mikko Hurme
30557-30567
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Epigallocatechin gallate affects glucose metabolism and increases fitness and lifespan in Drosophila melanogaster

Epigallocatechin gallate affects glucose metabolism and increases fitness and lifespan in Drosophila melanogaster

https://doi.org/10.18632/oncotarget.5215

Anika E. Wagner, Stefanie Piegholdt, Doerte Rabe, Nieves Baenas, Anke Schloesser, Manfred Eggersdorfer, Achim Stocker,  and Gerald Rimbach
30568-30578
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Research Papers: Pathology

Positron emission tomography imaging of cardiomyocyte apoptosis with a novel molecule probe [18F]FP-DPAZn2

Positron emission tomography imaging of cardiomyocyte apoptosis with a novel molecule probe [18F]FP-DPAZn2

https://doi.org/10.18632/oncotarget.5769

Ting Sun, Ganghua Tang, Hua Tian, Kongzhen Hu, Shaobo Yao, Yifan Su,  and Changqian Wang
30579-30591
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Rapid targeted somatic mutation analysis of solid tumors in routine clinical diagnostics

Rapid targeted somatic mutation analysis of solid tumors in routine clinical diagnostics

https://doi.org/10.18632/oncotarget.5190

Gilda Magliacane, Greta Grassini, Paola Bartocci, Ilaria Francaviglia, Elena Dal Cin, Gianluca Barbieri, Gianluigi Arrigoni, Lorenza Pecciarini, Claudio Doglioni,  and Maria Giulia Cangi
30592-30603
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Effects of normobaric oxygen and melatonin on reperfusion injury: role of cerebral microcirculation

Effects of normobaric oxygen and melatonin on reperfusion injury: role of cerebral microcirculation

https://doi.org/10.18632/oncotarget.5773

Mustafa C. Beker, Ahmet B. Caglayan, Taha Kelestemur, Berrak Caglayan, Esra Yalcin, Burak Yulug, Ulkan Kilic, Dirk M. Hermann,  and Ertugrul Kilic
30604-30614
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MCT4 surpasses the prognostic relevance of the ancillary protein CD147 in clear cell renal cell carcinoma

MCT4 surpasses the prognostic relevance of the ancillary protein CD147 in clear cell renal cell carcinoma

https://doi.org/10.18632/oncotarget.5593

Pascale Fisel, Viktoria Stühler, Jens Bedke, Stefan Winter, Steffen Rausch, Jörg Hennenlotter, Anne T. Nies, Arnulf Stenzl, Marcus Scharpf, Falko Fend, Stephan Kruck, Matthias Schwab,  and Elke Schaeffeler
30615-30627
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Low-dose ionizing radiation induces mitochondrial fusion and increases expression of mitochondrial complexes I and III in hippocampal neurons

Low-dose ionizing radiation induces mitochondrial fusion and increases expression of mitochondrial complexes I and III in hippocampal neurons

https://doi.org/10.18632/oncotarget.5790

Ling Chien, Wun-Ke Chen, Szu-Ting Liu, Chuang-Rung Chang, Mou-Chieh Kao, Kuan-Wei Chen, Shih-Che Chiu, Ming-Ling Hsu, I-Chou Hsiang, Yu-Jen Chen,  and Linyi Chen
30628-30639
Abstract  |  PDF  |  HTML  |  Order a Reprint

Endothelial tyrosine kinase receptor B prevents VE-cadherin cleavage and protects against atherosclerotic lesion development in ApoE−/− mice

Endothelial tyrosine kinase receptor B prevents VE-cadherin cleavage and protects against atherosclerotic lesion development in ApoE−/− mice

https://doi.org/10.18632/oncotarget.5855

Hong Jiang, Shuhong Huang, Xinyun Li, Xian Li, Shanying Huang, Yun Zhang,  and Zhe-Yu Chen
30640-30649
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Research Papers: Chromosome

Genome-wide array-CGH analysis reveals YRF1 gene copy number variation that modulates genetic stability in distillery yeasts

Genome-wide array-CGH analysis reveals YRF1 gene copy number variation that modulates genetic stability in distillery yeasts

https://doi.org/10.18632/oncotarget.5594

Anna Deregowska, Marek Skoneczny, Jagoda Adamczyk, Aleksandra Kwiatkowska, Ewa Rawska, Adrianna Skoneczna, Anna Lewinska,  and Maciej Wnuk
30650-30663
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A novel retroviral mutagenesis screen identifies prognostic genes in RUNX1 mediated myeloid leukemogenesis

A novel retroviral mutagenesis screen identifies prognostic genes in RUNX1 mediated myeloid leukemogenesis

https://doi.org/10.18632/oncotarget.5133

Dustin T. Rae, Jonah D. Hocum, Victor Bii, Joachim H. Deeg,  and Grant D. Trobridge
30664-30674
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Reviews

Progresses towards safe and efficient gene therapy vectors

Progresses towards safe and efficient gene therapy vectors

https://doi.org/10.18632/oncotarget.5169

Sergiu Chira, Carlo S. Jackson, Iulian Oprea, Ferhat Ozturk, Michael S. Pepper, Iulia Diaconu, Cornelia Braicu, Lajos-Zsolt Raduly, George A. Calin,  and Ioana Berindan-Neagoe
30675-30703
Abstract  |  PDF  |  HTML  |  Order a Reprint

Ovarian clear cell carcinoma meets metabolism; HNF-1β confers survival benefits through the Warburg effect and ROS reduction

Ovarian clear cell carcinoma meets metabolism; HNF-1β confers survival benefits through the Warburg effect and ROS reduction

https://doi.org/10.18632/oncotarget.5228

Masaki Mandai, Yasuaki Amano, Ken Yamaguchi, Noriomi Matsumura, Tsukasa Baba,  and Ikuo Konishi
30704-30714
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Approaches to isolation and molecular characterization of disseminated tumor cells

Approaches to isolation and molecular characterization of disseminated tumor cells

https://doi.org/10.18632/oncotarget.5568

Mark Jesus M. Magbanua, Rishi Das, Prithi Polavarapu,  and John W. Park
30715-30729
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Discovery of Compound A – a selective activator of the glucocorticoid receptor with anti-inflammatory and anti-cancer activity

Discovery of Compound A – a selective activator of the glucocorticoid receptor with anti-inflammatory and anti-cancer activity

https://doi.org/10.18632/oncotarget.5078

Ekaterina Lesovaya, Alexander Yemelyanov, Amanda C. Swart, Pieter Swart, Guy Haegeman,  and Irina Budunova
30730-30744
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Research Papers

Role of dual specificity tyrosine-phosphorylation-regulated kinase 1B (Dyrk1B) in S-phase entry of HPV E7 expressing cells from quiescence

Role of dual specificity tyrosine-phosphorylation-regulated kinase 1B (Dyrk1B) in S-phase entry of HPV E7 expressing cells from quiescence

https://doi.org/10.18632/oncotarget.5222

Na Zhou, Shoudao Yuan, Rongchun Wang, Weifang Zhang,  and Jason J. Chen
30745-30761
Abstract  |  PDF  |  HTML  |  Order a Reprint

Cell context-dependent dual effects of EFEMP1 stabilizes subpopulation equilibrium in responding to changes of in vivo growth environment

Cell context-dependent dual effects of EFEMP1 stabilizes subpopulation equilibrium in responding to changes of in vivo growth environment

https://doi.org/10.18632/oncotarget.5220

Yuanjie Hu, Chao Ke, Ning Ru, Yumay Chen, Liping Yu, Eric R. Siegel, Mark E. Linskey, Ping Wang,  and Yi-Hong Zhou
30762-30772
Abstract  |  PDF  |  HTML  |  Order a Reprint

Small molecule inhibition of the CHFR-PARP1 interaction as novel approach to overcome intrinsic taxane resistance in cancer

Small molecule inhibition of the CHFR-PARP1 interaction as novel approach to overcome intrinsic taxane resistance in cancer

https://doi.org/10.18632/oncotarget.5040

Seth A. Brodie, Ge Li, Donald Harvey, Fadlo R. Khuri, Paula M. Vertino,  and Johann C. Brandes
30773-30786
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Colorectal cancer-related mutant KRAS alleles function as positive regulators of autophagy

Colorectal cancer-related mutant KRAS alleles function as positive regulators of autophagy

https://doi.org/10.18632/oncotarget.5021

Sara Alves, Lisandra Castro, Maria Sofia Fernandes, Rita Francisco, Paula Castro, Muriel Priault, Susana Rodrigues Chaves, Mary Pat Moyer, Carla Oliveira, Raquel Seruca, Manuela Côrte-Real, Maria João Sousa,  and Ana Preto
30787-30802
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

XB130 promotes bronchioalveolar stem cell and Club cell proliferation in airway epithelial repair and regeneration

XB130 promotes bronchioalveolar stem cell and Club cell proliferation in airway epithelial repair and regeneration

https://doi.org/10.18632/oncotarget.5062

Hiroaki Toba, Yingchun Wang, Xiaohui Bai, Ricardo Zamel, Hae-Ra Cho, Hongmei Liu, Alonso Lira, Shaf Keshavjee,  and Mingyao Liu
30803-30817
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

MiRNA-101 inhibits breast cancer growth and metastasis by targeting CX chemokine receptor 7

MiRNA-101 inhibits breast cancer growth and metastasis by targeting CX chemokine receptor 7

https://doi.org/10.18632/oncotarget.5067

Jun-Tang Li, Lin-Tao Jia, Ning-Ning Liu, Xiao-Shan Zhu, Qin-Qin Liu, Xiu-Li Wang, Feng Yu, Yan-Li Liu, An-Gang Yang,  and Chun-Fang Gao
30818-30830
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Dehydroandrographolide, an iNOS inhibitor, extracted from Andrographis paniculata (Burm.f.) Nees, induces autophagy in human oral cancer cells

Dehydroandrographolide, an iNOS inhibitor, extracted from Andrographis paniculata (Burm.f.) Nees, induces autophagy in human oral cancer cells

https://doi.org/10.18632/oncotarget.5036

Ming-Ju Hsieh, Chiao-Wen Lin, Hui-Ling Chiou, Shun-Fa Yang,  and Mu-Kuan Chen
30831-30849
Abstract  |  PDF  |  HTML  |  Order a Reprint

Digital PCR analysis of plasma cell-free DNA for non-invasive detection of drug resistance mechanisms in EGFR mutant NSCLC: Correlation with paired tumor samples

Digital PCR analysis of plasma cell-free DNA for non-invasive detection of drug resistance mechanisms in EGFR mutant NSCLC: Correlation with paired tumor samples

https://doi.org/10.18632/oncotarget.5068

Hidenobu Ishii, Koichi Azuma, Kazuko Sakai, Akihiko Kawahara, Kazuhiko Yamada, Takaaki Tokito, Isamu Okamoto, Kazuto Nishio,  and Tomoaki Hoshino
30850-30858
Abstract  |  PDF  |  HTML  |  Order a Reprint

Novel Axl-driven signaling pathway and molecular signature characterize high-grade ovarian cancer patients with poor clinical outcome

Novel Axl-driven signaling pathway and molecular signature characterize high-grade ovarian cancer patients with poor clinical outcome

https://doi.org/10.18632/oncotarget.5087

Katia Rea, Patrizia Pinciroli, Marialuisa Sensi, Federica Alciato, Brigitte Bisaro, Ludmila Lozneanu, Francesco Raspagliesi, Floriana Centritto, Sara Cabodi, Paola Defilippi, Gian Carlo Avanzi, Silvana Canevari,  and Antonella Tomassetti
30859-30875
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Dclk1+ small intestinal epithelial tuft cells display the hallmarks of quiescence and self-renewal

Dclk1+ small intestinal epithelial tuft cells display the hallmarks of quiescence and self-renewal

https://doi.org/10.18632/oncotarget.5129

Parthasarathy Chandrakesan, Randal May, Dongfeng Qu, Nathaniel Weygant, Vivian E. Taylor, James D. Li, Naushad Ali, Sripathi M. Sureban, Michael Qante, Timothy C. Wang, Michael S. Bronze,  and Courtney W. Houchen
30876-30886
Abstract  |  PDF  |  HTML  |  Order a Reprint

URGCP/URG4 promotes apoptotic resistance in bladder cancer cells by activating NF-κB signaling

URGCP/URG4 promotes apoptotic resistance in bladder cancer cells by activating NF-κB signaling

https://doi.org/10.18632/oncotarget.5134

Minglong Wu, Junxing Chen, Yuxi Wang, Jinqian Hu, Chang Liu, Chunxiang Feng,  and Xiaoyong Zeng
30887-30901
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

POL5551, a novel and potent CXCR4 antagonist, enhances sensitivity to chemotherapy in pediatric ALL

POL5551, a novel and potent CXCR4 antagonist, enhances sensitivity to chemotherapy in pediatric ALL

https://doi.org/10.18632/oncotarget.5094

Edward Allan R. Sison, Daniel Magoon, Li Li, Colleen E. Annesley, Barbara Romagnoli, Garry J. Douglas, Gerald Tuffin, Johann Zimmermann,  and Patrick Brown
30902-30918
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

A novel far-red fluorescent xenograft model of ovarian carcinoma for preclinical evaluation of HER2-targeted immunotoxins

A novel far-red fluorescent xenograft model of ovarian carcinoma for preclinical evaluation of HER2-targeted immunotoxins

https://doi.org/10.18632/oncotarget.5130

Tatiana Zdobnova, Evgeniya Sokolova, Oleg Stremovskiy, Dmitry Karpenko, William Telford, Ilya Turchin, Irina Balalaeva,  and Sergey Deyev
30919-30928
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Low EGFR/MET ratio is associated with resistance to EGFR inhibitors in non-small cell lung cancer

Low EGFR/MET ratio is associated with resistance to EGFR inhibitors in non-small cell lung cancer

https://doi.org/10.18632/oncotarget.5131

Silvia Park, Emma Langley, Jong-Mu Sun, Steve Lockton, Jin Seok Ahn, Anjali Jain, Keunchil Park, Sharat Singh, Phillip Kim,  and Myung-Ju Ahn
30929-30938
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

B5, a thioredoxin reductase inhibitor, induces apoptosis in human cervical cancer cells by suppressing the thioredoxin system, disrupting mitochondrion-dependent pathways and triggering autophagy

B5, a thioredoxin reductase inhibitor, induces apoptosis in human cervical cancer cells by suppressing the thioredoxin system, disrupting mitochondrion-dependent pathways and triggering autophagy

https://doi.org/10.18632/oncotarget.5132

Fang-Yuan Shao, Zhi-Yun Du, Dong-Lei Ma, Wen-Bo Chen, Wu-Yu Fu, Bi-Bo Ruan, Wen Rui, Jia-Xuan Zhang, Sheng Wang, Nai Sum Wong, Hao Xiao, Man-Mei Li, Xiao Liu, Qiu-Ying Liu, Xiao-dong Zhou, Hai-Zhao Yan, Yi-Fei Wang, Chang-Yan Chen, Zhong Liu,  and Hong-Yuan Chen
30939-30956
Abstract  |  PDF  |  HTML  |  Order a Reprint

PRMT6 increases cytoplasmic localization of p21CDKN1A in cancer cells through arginine methylation and makes more resistant to cytotoxic agents

PRMT6 increases cytoplasmic localization of p21CDKN1A in cancer cells through arginine methylation and makes more resistant to cytotoxic agents

https://doi.org/10.18632/oncotarget.5143

Makoto Nakakido, Zhenzhong Deng, Takehiro Suzuki, Naoshi Dohmae, Yusuke Nakamura,  and Ryuji Hamamoto
30957-30967
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Comprehensive portrait of recurrent glioblastoma multiforme in molecular and clinical characteristics

Comprehensive portrait of recurrent glioblastoma multiforme in molecular and clinical characteristics

https://doi.org/10.18632/oncotarget.5038

Rui Li, Xincheng Chen, Yongping You, Xiefeng Wang, Yanwei Liu, Qi Hu,  and Wei Yan
30968-30974
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Anxa2 binds to STAT3 and promotes epithelial to mesenchymal transition in breast cancer cells

Anxa2 binds to STAT3 and promotes epithelial to mesenchymal transition in breast cancer cells

https://doi.org/10.18632/oncotarget.5199

Tong Wang, Jie Yuan, Jie Zhang, Ran Tian, Wei Ji, Yan Zhou, Yi Yang, Weijie Song, Fei Zhang,  and Ruifang Niu
30975-30992
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Achaete scute-like 2 suppresses CDX2 expression and inhibits intestinal neoplastic epithelial cell differentiation

Achaete scute-like 2 suppresses CDX2 expression and inhibits intestinal neoplastic epithelial cell differentiation

https://doi.org/10.18632/oncotarget.5206

Yangyang Shang, Qiong Pan, Lei Chen, Jun Ye, Xiaoli Zhong, Xiaohuan Li, Linkuan Meng, Jin Guo, Yin Tian, Yonghong He, Wensheng Chen, Zhihong Peng,  and Rongquan Wang
30993-31006
Abstract  |  PDF  |  HTML  |  Order a Reprint

Aberrant mesenchymal differentiation of glioma stem-like cells: implications for therapeutic targeting

Aberrant mesenchymal differentiation of glioma stem-like cells: implications for therapeutic targeting

https://doi.org/10.18632/oncotarget.5219

Veerakumar Balasubramaniyan, Brian Vaillant, Shuzhen Wang, Joy Gumin, M. Elena Butalid, Ke Sai, Farah Mukheef, Se Hoon Kim, H.W.G.M. Boddeke, Frederick Lang, Kenneth Aldape, Erik P. Sulman, Krishna P. Bhat,  and Howard Colman
31007-31017
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Targeted therapy for Epstein-Barr virus-associated gastric carcinoma using low-dose gemcitabine-induced lytic activation

Targeted therapy for Epstein-Barr virus-associated gastric carcinoma using low-dose gemcitabine-induced lytic activation

https://doi.org/10.18632/oncotarget.5041

Hyun Gyu Lee, Hyemi Kim, Eun Jung Kim, Pil-Gu Park, Seung Myung Dong, Tae Hyun Choi, Hyunki Kim, Curtis R. Chong, Jun O. Liu, Jianmeng Chen, Richard F. Ambinder, S. Diane Hayward, Jeon Han Park,  and Jae Myun Lee
31018-31029
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Transcriptome analysis indicates TFEB1 and YEATS4 as regulatory transcription factors for drug resistance of ovarian cancer

Transcriptome analysis indicates TFEB1 and YEATS4 as regulatory transcription factors for drug resistance of ovarian cancer

https://doi.org/10.18632/oncotarget.5208

Yi Rang Kim, Mi Sung Park, Ki Hwan Eum, Juhee Kim, Jeong Won Lee, Taejeong Bae, Dae Ho Lee,  and Jin Woo Choi
31030-31038
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Sub-apoptotic dosages of pro-oxidant vitamin cocktails sensitize human melanoma cells to NK cell lysis

Sub-apoptotic dosages of pro-oxidant vitamin cocktails sensitize human melanoma cells to NK cell lysis

https://doi.org/10.18632/oncotarget.5024

Elisa Tremante, Lory Santarelli, Elisa Lo Monaco, Camilla Sampaoli, Tiziano Ingegnere, Roberto Guerrieri, Marco Tomasetti,  and Patrizio Giacomini
31039-31049
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Glioma cell VEGFR-2 confers resistance to chemotherapeutic and antiangiogenic treatments in PTEN-deficient glioblastoma

Glioma cell VEGFR-2 confers resistance to chemotherapeutic and antiangiogenic treatments in PTEN-deficient glioblastoma

https://doi.org/10.18632/oncotarget.2910

Tobias Kessler, Felix Sahm, Jonas Blaes, Matthias Osswald, Petra Rübmann, David Milford, Severino Urban, Leonie Jestaedt, Sabine Heiland, Martin Bendszus, Anne Hertenstein, Philipp-Niclas Pfenning, Carmen Ruiz de Almodóvar, Antje Wick, Frank Winkler, Andreas von Deimling, Michael Platten, Wolfgang Wick,  and Markus Weiler
31050-31068
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CEBPD amplification and overexpression in urothelial carcinoma: a driver of tumor metastasis indicating adverse prognosis

CEBPD amplification and overexpression in urothelial carcinoma: a driver of tumor metastasis indicating adverse prognosis

https://doi.org/10.18632/oncotarget.5209

Yu-Hui Wang, Wen-Jeng Wu, Wei-Jan Wang, Hsuan-Ying Huang, Wei-Ming Li, Bi-Wen Yeh, Ting-Feng Wu, Yow-Ling Shiue, Jim Jinn-Chyuan Sheu, Ju-Ming Wang,  and Chien-Feng Li
31069-31084
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Focal adhesion kinase overexpression and its impact on human osteosarcoma

Focal adhesion kinase overexpression and its impact on human osteosarcoma

https://doi.org/10.18632/oncotarget.5044

Ke Ren, Xiao Lu, Nan Yao, Yong Chen, Aizhen Yang, Hui Chen, Jian Zhang, Sujia Wu, Xin Shi, Chen Wang,  and Xiaoliang Sun
31085-31103
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A strategy to combine pathway-targeted low toxicity drugs in ovarian cancer

A strategy to combine pathway-targeted low toxicity drugs in ovarian cancer

https://doi.org/10.18632/oncotarget.5093

Joe R Delaney, Chandni Patel, Katelyn E McCabe, Dan Lu, Mitzie-Ann Davis, Isabelle Tancioni, Tami von Schalscha, Alena Bartakova, Carley Haft, David D Schlaepfer,  and Dwayne G Stupack
31104-31118
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Hydrogen peroxide mediates hyperglycemia-induced invasive activity via ERK and p38 MAPK in human pancreatic cancer

Hydrogen peroxide mediates hyperglycemia-induced invasive activity via ERK and p38 MAPK in human pancreatic cancer

https://doi.org/10.18632/oncotarget.5045

Wei Li, Zhenhua Ma, Jiguang Ma, Xuqi Li, Qinhong Xu, Wanxing Duan, Xin Chen, Yunfu Lv, Shuang Zhou, Erxi Wu, Qingyong Ma,  and Xiongwei Huo
31119-31133
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HDAC inhibitor AR-42 decreases CD44 expression and sensitizes myeloma cells to lenalidomide

HDAC inhibitor AR-42 decreases CD44 expression and sensitizes myeloma cells to lenalidomide

https://doi.org/10.18632/oncotarget.5290

Alessandro Canella, Hector Cordero Nieves, Douglas W. Sborov, Luciano Cascione, Hanna S. Radomska, Emily Smith, Andrew Stiff, Jessica Consiglio, Enrico Caserta, Lara Rizzotto, Nicola Zanesi, Volinia Stefano, Balveen Kaur, Xiaokui Mo, John C. Byrd, Yvonne A. Efebera, Craig C. Hofmeister,  and Flavia Pichiorri
31134-31150
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Inhibition of glutamine metabolism counteracts pancreatic cancer stem cell features and sensitizes cells to radiotherapy

Inhibition of glutamine metabolism counteracts pancreatic cancer stem cell features and sensitizes cells to radiotherapy

https://doi.org/10.18632/oncotarget.5150

Doudou Li, Zhiqiang Fu, Ruiwan Chen, Xiaohui Zhao, Yu Zhou, Bing Zeng, Min Yu, Quanbo Zhou, Qing Lin, Wenchao Gao, Huilin Ye, Jiajia Zhou, Zhihua Li, Yimin Liu,  and Rufu Chen
31151-31163
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Human mesenchymal stem cells enhance the systemic effects of radiotherapy

Human mesenchymal stem cells enhance the systemic effects of radiotherapy

https://doi.org/10.18632/oncotarget.5216

Virgínea de Araújo Farias, Francisco O’Valle, Borja Alonso Lerma, Carmen Ruiz de Almodóvar, Jesús J. López-Peñalver, Ana Nieto, Ana Santos, Beatriz Irene Fernández, Ana Guerra-Librero, María Carmen Ruiz-Ruiz, Damián Guirado, Thomas Schmidt, Francisco Javier Oliver,  and José Mariano Ruiz de Almodóvar
31164-31180
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Overexpression of CHD1L is positively associated with metastasis of lung adenocarcinoma and predicts patients poor survival

Overexpression of CHD1L is positively associated with metastasis of lung adenocarcinoma and predicts patients poor survival

https://doi.org/10.18632/oncotarget.5070

Li-Ru He, Ning-Fang Ma, Jie-Wei Chen, Bin-Kui Li, Xin-Yuan Guan, Meng-Zhong Liu,  and Dan Xie
31181-31190
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Suppression of CD300A inhibits the growth of diffuse large B-cell lymphoma

Suppression of CD300A inhibits the growth of diffuse large B-cell lymphoma

https://doi.org/10.18632/oncotarget.5152

Lei Jiang, Yulian Xu, Xinli Zeng, Jianchen Fang, Herbert C. Morse III,  and Jeff X. Zhou
31191-31202
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Androgen receptor (AR) suppresses miRNA-145 to promote renal cell carcinoma (RCC) progression independent of VHL status

Androgen receptor (AR) suppresses miRNA-145 to promote renal cell carcinoma (RCC) progression independent of VHL status

https://doi.org/10.18632/oncotarget.4522

Yuan Chen, Yin Sun, Qun Rao, Hua Xu, Lei Li,  and Chawnshang Chang
31203-31215
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Apigenin blocks IKKα activation and suppresses prostate cancer progression

Apigenin blocks IKKα activation and suppresses prostate cancer progression

https://doi.org/10.18632/oncotarget.5157

Sanjeev Shukla, Rajnee Kanwal, Eswar Shankar, Manish Datt, Mark R. Chance, Pingfu Fu, Gregory T. MacLennan,  and Sanjay Gupta
31216-31232
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Restriction of dietary protein decreases mTORC1 in tumors and somatic tissues of a tumor-bearing mouse xenograft model

Restriction of dietary protein decreases mTORC1 in tumors and somatic tissues of a tumor-bearing mouse xenograft model

https://doi.org/10.18632/oncotarget.5180

Dudley W. Lamming, Nicole E. Cummings, Antonella L. Rastelli, Feng Gao, Edda Cava, Beatrice Bertozzi, Francesco Spelta, Roberto Pili,  and Luigi Fontana
31233-31240
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Upregulation of sex-determining region Y-box 9 (SOX9) promotes cell proliferation and tumorigenicity in esophageal squamous cell carcinoma

Upregulation of sex-determining region Y-box 9 (SOX9) promotes cell proliferation and tumorigenicity in esophageal squamous cell carcinoma

https://doi.org/10.18632/oncotarget.5160

Yingcai Hong, Wen Chen, Xiaojun Du, Huiwen Ning, Huaisheng Chen, Ruiqing Shi, Shaolin Lin, Rongyu Xu, Jinrong Zhu, Shu Wu,  and Haiyu Zhou
31241-31254
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The association analysis of lncRNA HOTAIR genetic variants and gastric cancer risk in a Chinese population

The association analysis of lncRNA HOTAIR genetic variants and gastric cancer risk in a Chinese population

https://doi.org/10.18632/oncotarget.5158

Mulong Du, Weizhi Wang, Hua Jin, Qiaoyan Wang, Yuqiu Ge, Jiafei Lu, Gaoxiang Ma, Haiyan Chu, Na Tong, Haixia Zhu, Meilin Wang, Fulin Qiang,  and Zhengdong Zhang
31255-31262
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Acceleration of atherogenesis in ApoE−/− mice exposed to acute or low-dose-rate ionizing radiation

Acceleration of atherogenesis in ApoE−/− mice exposed to acute or low-dose-rate ionizing radiation

https://doi.org/10.18632/oncotarget.5075

Mariateresa Mancuso, Emanuela Pasquali, Ignacia Braga-Tanaka III, Satoshi Tanaka, Alessandro Pannicelli, Paola Giardullo, Simonetta Pazzaglia, Soile Tapio, Michael J Atkinson,  and Anna Saran
31263-31271
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Phospho-kinase profile of colorectal tumors guides in the selection of multi-kinase inhibitors

Phospho-kinase profile of colorectal tumors guides in the selection of multi-kinase inhibitors

https://doi.org/10.18632/oncotarget.5211

Gemma Serrano-Heras, María Dolores Cuenca-López, Juan Carlos Montero, Verónica Corrales-Sanchez, Jorge Carlos Morales, Luz-Elena Núñez, Francisco Moris, Atanasio Pandiella,  and Alberto Ocaña
31272-31283
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Revealing very small FLT3 ITD mutated clones by ultra-deep sequencing analysis has important clinical implications in AML patients

Revealing very small FLT3 ITD mutated clones by ultra-deep sequencing analysis has important clinical implications in AML patients

https://doi.org/10.18632/oncotarget.5161

Elisa Zuffa, Eugenia Franchini, Cristina Papayannidis, Carmen Baldazzi, Giorgia Simonetti, Nicoletta Testoni, Maria Chiara Abbenante, Stefania Paolini, Chiara Sartor, Sarah Parisi, Giovanni Marconi, Federica Cattina, Maria Teresa Bochicchio, Claudia Venturi, Emanuela Ottaviani, Michele Cavo,  and Giovanni Martinelli
31284-31294
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A cytoplasmic C-terminal fragment of syndecan-1 is generated by sequential proteolysis and antagonizes syndecan-1 dependent lung tumor cell migration

A cytoplasmic C-terminal fragment of syndecan-1 is generated by sequential proteolysis and antagonizes syndecan-1 dependent lung tumor cell migration

https://doi.org/10.18632/oncotarget.5174

Tobias Pasqualon, Jessica Pruessmeyer, Vera Jankowski, Aaron Babendreyer, Esther Groth, Julian Schumacher, Andrea Koenen, Sarah Weidenfeld, Nicole Schwarz, Bernd Denecke, Holger Jahr, Daniela Dreymueller, Joachim Jankowski,  and Andreas Ludwig
31295-31312
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Ibrutinib selectively and irreversibly targets EGFR (L858R, Del19) mutant but is moderately resistant to EGFR (T790M) mutant NSCLC Cells

Ibrutinib selectively and irreversibly targets EGFR (L858R, Del19) mutant but is moderately resistant to EGFR (T790M) mutant NSCLC Cells

https://doi.org/10.18632/oncotarget.5182

Hong Wu, Aoli Wang, Wei Zhang, Beilei Wang, Cheng Chen, Wenchao Wang, Chen Hu, Zi Ye, Zheng Zhao, Li Wang, Xixiang Li, Kailin Yu, Juan Liu, Jiaxin Wu, Xiao-E Yan, Peng Zhao, Jinhua Wang, Chu Wang, Ellen L. Weisberg, Nathanael S. Gray, Cai-Hong Yun, Jing Liu, Liang Chen,  and Qingsong Liu
31313-31322
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Application of a patient-derived xenograft model in cytolytic viral activation therapy for nasopharyngeal carcinoma

Application of a patient-derived xenograft model in cytolytic viral activation therapy for nasopharyngeal carcinoma

https://doi.org/10.18632/oncotarget.5544

Cheng-Lung Hsu, Yung-Chia Kuo, Yenlin Huang, Yin-Cheng Huang, Kar-Wai Lui, Kai-Ping Chang, Tung-Liang Lin, Hsien-Chi Fan, An-Chi Lin, Chia-Hsun Hsieh, Li-Yu Lee, Hung-Ming Wang, Hsin-Pai Li,  and Yu-Sun Chang
31323-31334
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Tumor-targeting Salmonella typhimurium A1-R inhibits human prostate cancer experimental bone metastasis in mouse models

Tumor-targeting Salmonella typhimurium A1-R inhibits human prostate cancer experimental bone metastasis in mouse models

https://doi.org/10.18632/oncotarget.5866

Makoto Toneri, Shinji Miwa, Yong Zhang, Cameron Hu, Shuya Yano, Yasunori Matsumoto, Michael Bouvet, Hayao Nakanishi, Robert M. Hoffman,  and Ming Zhao
31335-31343
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The generation and analyses of a novel combination of recombinant adenovirus vaccines targeting three tumor antigens as an immunotherapeutic

The generation and analyses of a novel combination of recombinant adenovirus vaccines targeting three tumor antigens as an immunotherapeutic

https://doi.org/10.18632/oncotarget.5181

Elizabeth S. Gabitzsch, Kwong Yok Tsang, Claudia Palena, Justin David, Massimo Fantini, Anna Kwilas, Adrian E. Rice, Yvette Latchman, James W. Hodge, James L. Gulley, Ravi A. Madan, Christopher R. Heery, Joseph P. Balint Jr., Frank R. Jones,  and Jeffrey Schlom
31344-31359
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Genetic variations in the TERT and CLPTM1L gene region and gastrointestinal stromal tumors risk

Genetic variations in the TERT and CLPTM1L gene region and gastrointestinal stromal tumors risk

https://doi.org/10.18632/oncotarget.5153

Rui Zhang, Jian Zhao, Jian Xu, Fang Liu, Yongqing Xu, Xianmin Bu, Chaoliu Dai,  and Chun Song
31360-31367
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Therapeutic efficacy of tumor-targeting Salmonella typhimurium A1-R on human colorectal cancer liver metastasis in orthotopic nude-mouse models

Therapeutic efficacy of tumor-targeting Salmonella typhimurium A1-R on human colorectal cancer liver metastasis in orthotopic nude-mouse models

https://doi.org/10.18632/oncotarget.5187

Takashi Murakami, Yukihiko Hiroshima, Ming Zhao, Yong Zhang, Takashi Chishima, Kuniya Tanaka, Michael Bouvet, Itaru Endo,  and Robert M. Hoffman
31368-31377
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Constitutive activation of MET signaling impairs myogenic differentiation of rhabdomyosarcoma and promotes its development and progression

Constitutive activation of MET signaling impairs myogenic differentiation of rhabdomyosarcoma and promotes its development and progression

https://doi.org/10.18632/oncotarget.5145

Klaudia Skrzypek, Anna Kusienicka, Barbara Szewczyk, Tomasz Adamus, Ewa Lukasiewicz, Katarzyna Miekus,  and Marcin Majka
31378-31398
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

CDK1 phosphorylation of TAZ in mitosis inhibits its oncogenic activity

CDK1 phosphorylation of TAZ in mitosis inhibits its oncogenic activity

https://doi.org/10.18632/oncotarget.5189

Lin Zhang, Xingcheng Chen, Seth Stauffer, Shuping Yang, Yuanhong Chen,  and Jixin Dong
31399-31412
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Extracellular vesicle-mediated transfer of CLIC1 protein is a novel mechanism for the regulation of glioblastoma growth

Extracellular vesicle-mediated transfer of CLIC1 protein is a novel mechanism for the regulation of glioblastoma growth

https://doi.org/10.18632/oncotarget.5105

Matteo Setti, Daniela Osti, Cristina Richichi, Barbara Ortensi, Massimiliano Del Bene, Lorenzo Fornasari, Galina Beznoussenko, Alexandre Mironov, Germana Rappa, Alessandro Cuomo, Mario Faretta, Tiziana Bonaldi, Aurelio Lorico,  and Giuliana Pelicci
31413-31427
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Proteolytic systems and AMP-activated protein kinase are critical targets of acute myeloid leukemia therapeutic approaches

Proteolytic systems and AMP-activated protein kinase are critical targets of acute myeloid leukemia therapeutic approaches

https://doi.org/10.18632/oncotarget.2947

Ângela Fernandes, Maria M. Azevedo, Olga Pereira, Belém Sampaio-Marques, Artur Paiva, Margarida Correia-Neves, Isabel Castro,  and Paula Ludovico
31428-31440
Abstract  |  PDF  |  HTML  |  Order a Reprint

Integrated gene and miRNA expression analysis of prostate cancer associated fibroblasts supports a prominent role for interleukin-6 in fibroblast activation

Integrated gene and miRNA expression analysis of prostate cancer associated fibroblasts supports a prominent role for interleukin-6 in fibroblast activation

https://doi.org/10.18632/oncotarget.5056

Valentina Doldi, Maurizio Callari, Elisa Giannoni, Francesca D’Aiuto, Massimo Maffezzini, Riccardo Valdagni, Paola Chiarugi, Paolo Gandellini,  and Nadia Zaffaroni
31441-31460
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Self-assembling nanoparticles encapsulating zoledronic acid revert multidrug resistance in cancer cells

Self-assembling nanoparticles encapsulating zoledronic acid revert multidrug resistance in cancer cells

https://doi.org/10.18632/oncotarget.5058

Joanna Kopecka, Stefania Porto, Sara Lusa, Elena Gazzano, Giuseppina Salzano, Antonio Giordano, Vincenzo Desiderio, Dario Ghigo, Michele Caraglia, Giuseppe De Rosa,  and Chiara Riganti
31461-31478
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Interferon-regulatory factor-1 (IRF1) regulates bevacizumab induced autophagy

Interferon-regulatory factor-1 (IRF1) regulates bevacizumab induced autophagy

https://doi.org/10.18632/oncotarget.5491

Ji Liang, Yuji Piao, Verlene Henry, Ningyi Tiao,  and John F. de Groot
31479-31492
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Integrin α9 gene promoter is hypermethylated and downregulated in nasopharyngeal carcinoma

Integrin α9 gene promoter is hypermethylated and downregulated in nasopharyngeal carcinoma

https://doi.org/10.18632/oncotarget.5154

Imran Nawaz, Li-Fu Hu, Zi-Ming Du, Khalid Moumad, Ilya Ignatyev, Tatiana V. Pavlova, Vladimir Kashuba, Malin Almgren, Eugene R. Zabarovsky,  and Ingemar Ernberg
31493-31507
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Cx25 contributes to leukemia cell communication and chemosensitivity

Cx25 contributes to leukemia cell communication and chemosensitivity

https://doi.org/10.18632/oncotarget.5226

Maksim Sinyuk, Alvaro G. Alvarado, Pavel Nesmiyanov, Jeremy Shaw, Erin E. Mulkearns-Hubert, Jennifer T. Eurich, James S. Hale, Anna Bogdanova, Masahiro Hitomi, Jaroslaw Maciejewski, Alex Y. Huang, Yogen Saunthararajah,  and Justin D. Lathia
31508-31521
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BCAT1 expression associates with ovarian cancer progression: possible implications in altered disease metabolism

BCAT1 expression associates with ovarian cancer progression: possible implications in altered disease metabolism

https://doi.org/10.18632/oncotarget.5159

Zhi-Qiang Wang, Adnen Faddaoui, Magdalena Bachvarova, Marie Plante, Jean Gregoire, Marie-Claude Renaud, Alexandra Sebastianelli, Chantal Guillemette, Stéphane Gobeil, Elizabeth Macdonald, Barbara Vanderhyden,  and Dimcho Bachvarov
31522-31543
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

The significance of PIWI family expression in human lung embryogenesis and non-small cell lung cancer

The significance of PIWI family expression in human lung embryogenesis and non-small cell lung cancer

https://doi.org/10.18632/oncotarget.3003

Alfons Navarro, Rut Tejero, Nuria Viñolas, Anna Cordeiro, Ramon M. Marrades, Dolors Fuster, Oriol Caritg, Jorge Moises, Carmen Muñoz, Laureano Molins, Josep Ramirez,  and Mariano Monzo
31544-31556
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Necdin is a breast cancer metastasis suppressor that regulates the transcription of c-Myc

Necdin is a breast cancer metastasis suppressor that regulates the transcription of c-Myc

https://doi.org/10.18632/oncotarget.5230

Minnkyong Lee, Sarah M. Beggs, Derek Gildea, Sujata Bupp, Jens Lichtenberg, Niraj S. Trivedi, NISC Comparative Sequencing Program, Ying Hu, David M. Bodine,  and Nigel P.S. Crawford
31557-31568
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Decoding c-Myc networks of cell cycle and apoptosis regulated genes in a transgenic mouse model of papillary lung adenocarcinomas

Decoding c-Myc networks of cell cycle and apoptosis regulated genes in a transgenic mouse model of papillary lung adenocarcinomas

https://doi.org/10.18632/oncotarget.5035

Yari Ciribilli, Prashant Singh, Reinhard Spanel, Alberto Inga,  and Jürgen Borlak
31569-31592
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

The role of interleukin-8 (IL-8) and IL-8 receptors in platinum response in high grade serous ovarian carcinoma

The role of interleukin-8 (IL-8) and IL-8 receptors in platinum response in high grade serous ovarian carcinoma

https://doi.org/10.18632/oncotarget.3415

Euan A. Stronach, Paula Cunnea, Christina Turner, Tankut Guney, Radhika Aiyappa, Senthuran Jeyapalan, Camila H. de Sousa, Alacoque Browne, Nesreen Magdy, James B. Studd, Ruethairat Sriraksa, Hani Gabra,  and Mona El-Bahrawy
31593-31603
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Prognostic significance of K-Ras mutation rate in metastatic colorectal cancer patients

Prognostic significance of K-Ras mutation rate in metastatic colorectal cancer patients

https://doi.org/10.18632/oncotarget.5231

Bruno Vincenzi, Chiara Cremolini, Andrea Sartore-Bianchi, Antonio Russo, Francesco Mannavola, Giuseppe Perrone, Francesco Pantano, Fotios Loupakis, Daniele Rossini, Elena Ongaro, Erica Bonazzina, Emanuela Dell’Aquila, Marco Imperatori, Alice Zoccoli, Giuseppe Bronte, Giovanna De Maglio, Gabriella Fontanini, Clara Natoli, Alfredo Falcone, Daniele Santini, Andrea Onetti-Muda, Salvatore Siena, Giuseppe Tonini,  and Giuseppe Aprile
31604-31612
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The lincRNA HOTAIRM1, located in the HOXA genomic region, is expressed in acute myeloid leukemia, impacts prognosis in patients in the intermediate-risk cytogenetic category, and is associated with a distinctive microRNA signature

The lincRNA HOTAIRM1, located in the HOXA genomic region, is expressed in acute myeloid leukemia, impacts prognosis in patients in the intermediate-risk cytogenetic category, and is associated with a distinctive microRNA signature

https://doi.org/10.18632/oncotarget.5148

Marina Díaz-Beyá, Salut Brunet, Josep Nomdedéu, Marta Pratcorona, Anna Cordeiro, David Gallardo, Lourdes Escoda, Mar Tormo, Inmaculada Heras, Josep Maria Ribera, Rafael Duarte, María Paz Queipo de Llano, Joan Bargay, Antonia Sampol, Mertixell Nomdedeu, Ruth M. Risueño, Montserrat Hoyos, Jorge Sierra, Mariano Monzo, Alfons Navarro, Jordi Esteve,  and on behalf of the Cooperative AML group CETLAM
31613-31627
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Tumor driven by gain-of-function HER2 H878Y mutant is highly sensitive to HER2 inhibitor

Tumor driven by gain-of-function HER2 H878Y mutant is highly sensitive to HER2 inhibitor

https://doi.org/10.18632/oncotarget.5221

Zexi Hu, Yong Hu, Xicheng Liu, Rongwen Xi, Aiqun Zhang, Deruo Liu, Qiang Xie,  and Liang Chen
31628-31639
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

c-Met inhibitors attenuate tumor growth of small cell hypercalcemic ovarian carcinoma (SCCOHT) populations

c-Met inhibitors attenuate tumor growth of small cell hypercalcemic ovarian carcinoma (SCCOHT) populations

https://doi.org/10.18632/oncotarget.5151

Anna Otte, Finn Rauprich, Juliane von der Ohe, Yuanyuan Yang, Friedrich Kommoss, Friedrich Feuerhake, Peter Hillemanns,  and Ralf Hass
31640-31658
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Activin B induces human endometrial cancer cell adhesion, migration and invasion by up-regulating integrin β3 via SMAD2/3 signaling

Activin B induces human endometrial cancer cell adhesion, migration and invasion by up-regulating integrin β3 via SMAD2/3 signaling

https://doi.org/10.18632/oncotarget.5229

Siyuan Xiong, Christian Klausen, Jung-Chien Cheng, Hua Zhu,  and Peter C.K. Leung
31659-31673
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

CRC-113 gene expression signature for predicting prognosis in patients with colorectal cancer

CRC-113 gene expression signature for predicting prognosis in patients with colorectal cancer

https://doi.org/10.18632/oncotarget.5183

Minh Nam Nguyen, Tae Gyu Choi, Dinh Truong Nguyen, Jin-Hwan Kim, Yong Hwa Jo, Muhammad Shahid, Salima Akter, Saurav Nath Aryal, Ji Youn Yoo, Yong-Joo Ahn, Kyoung Min Cho, Ju-Seog Lee, Wonchae Choe, Insug Kang, Joohun Ha,  and Sung Soo Kim
31674-31692
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

A four gene signature predicts benefit from anthracyclines: evidence from the BR9601 and MA.5 clinical trials

A four gene signature predicts benefit from anthracyclines: evidence from the BR9601 and MA.5 clinical trials

https://doi.org/10.18632/oncotarget.5562

Melanie Spears, Fouad Yousif, Nicola Lyttle, Paul C. Boutros, Alison F. Munro, Chris Twelves, Kathleen I. Pritchard, Mark N. Levine, Lois Shepherd,  and John MS. Bartlett
31693-31701
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

KDM4B and KDM4A promote endometrial cancer progression by regulating androgen receptor, c-myc, and p27kip1

KDM4B and KDM4A promote endometrial cancer progression by regulating androgen receptor, c-myc, and p27kip1

https://doi.org/10.18632/oncotarget.5165

Mei-Ting Qiu, Qiong Fan, Zhu Zhu, Suet-Ying Kwan, Limo Chen, Jin-Hong Chen, Zuo-Lin Ying, Ye Zhou, Wei Gu, Li-Hua Wang, Wei-Wei Cheng, Jianfang Zeng, Xiao-Ping Wan, Samuel C. Mok, Kwong-Kwok Wong,  and Wei Bao
31702-31720
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Distinct breast cancer stem/progenitor cell populations require either HIF1α or loss of PHD3 to expand under hypoxic conditions

Distinct breast cancer stem/progenitor cell populations require either HIF1α or loss of PHD3 to expand under hypoxic conditions

https://doi.org/10.18632/oncotarget.5564

Oihana Iriondo, Miriam Rábano, Giacomo Domenici, Onintza Carlevaris, José Antonio López-Ruiz, Ignacio Zabalza, Edurne Berra,  and Maria dM Vivanco
31721-31739
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Genotoxic stress inhibits Ewing sarcoma cell growth by modulating alternative pre-mRNA processing of the RNA helicase DHX9

Genotoxic stress inhibits Ewing sarcoma cell growth by modulating alternative pre-mRNA processing of the RNA helicase DHX9

https://doi.org/10.18632/oncotarget.5033

Marco Fidaleo, Francesca Svetoni, Elisabetta Volpe, Belén Miñana, Daniela Caporossi,  and Maria Paola Paronetto
31740-31757
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Expression of prokineticin-receptor2(PK-R2) is a new prognostic factor in human colorectal cancer

Expression of prokineticin-receptor2(PK-R2) is a new prognostic factor in human colorectal cancer

https://doi.org/10.18632/oncotarget.5565

Takanori Goi, Hidetaka Kurebayashi, Yuki Ueda, Takayuki Naruse, Toshiyuki Nakazawa, Kenji Koneri, Yasuo Hirono, Kanji Katayama,  and Akio Yamaguchi
31758-31766
Abstract  |  PDF  |  HTML  |  Order a Reprint

Targeting HSF1 disrupts HSP90 chaperone function in chronic lymphocytic leukemia

Targeting HSF1 disrupts HSP90 chaperone function in chronic lymphocytic leukemia

https://doi.org/10.18632/oncotarget.5167

Siddhartha Ganguly, Trisha Home, Abdulraheem Yacoub, Suman Kambhampati, Huidong Shi, Prasad Dandawate, Subhash Padhye, Ashok K. Saluja, Joseph McGuirk,  and Rekha Rao
31767-31779
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Down-regulation of SOSTDC1 promotes thyroid cancer cell proliferation via regulating cyclin A2 and cyclin E2

Down-regulation of SOSTDC1 promotes thyroid cancer cell proliferation via regulating cyclin A2 and cyclin E2

https://doi.org/10.18632/oncotarget.5566

Weiwei Liang, Hongyu Guan, Xiaoying He, Weijian Ke, Lijuan Xu, Liehua Liu, Haipeng Xiao,  and Yanbing Li
31780-31791
Abstract  |  PDF  |  HTML  |  Order a Reprint

Modulation of thyroidal radioiodide uptake by oncological pipeline inhibitors and Apigenin

Modulation of thyroidal radioiodide uptake by oncological pipeline inhibitors and Apigenin

https://doi.org/10.18632/oncotarget.5172

Aparna Lakshmanan, Daniel Scarberry, Jill A. Green, Xiaoli Zhang, Samia Selmi-Ruby,  and Sissy M. Jhiang
31792-31804
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Mutation of cysteine 46 in IKK-beta increases inflammatory responses

Mutation of cysteine 46 in IKK-beta increases inflammatory responses

https://doi.org/10.18632/oncotarget.5567

Ting Li, Vincent Kam Wai Wong, Zhi Hong Jiang, Shui Ping Jiang, Yan Liu, Ting Yu Wang, Xiao Jun Yao, Xiao Hui Su, Feng Gen Yan, Juan Liu, Elaine Lai-Han Leung, Xiao Qin Yi, Yuen Fan Wong, Hua Zhou,  and Liang Liu
31805-31819
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Comparative genomic analysis reveals bilateral breast cancers are genetically independent

Comparative genomic analysis reveals bilateral breast cancers are genetically independent

https://doi.org/10.18632/oncotarget.5569

Fangfang Song, Xiangchun Li, Fengju Song, Yanrui Zhao, Haixin Li, Hong Zheng, Zhibo Gao, Jun Wang, Wei Zhang,  and Kexin Chen
31820-31829
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

sMEK1 inhibits endothelial cell proliferation by attenuating VEGFR-2-dependent-Akt/eNOS/HIF-1α signaling pathways

sMEK1 inhibits endothelial cell proliferation by attenuating VEGFR-2-dependent-Akt/eNOS/HIF-1α signaling pathways

https://doi.org/10.18632/oncotarget.5570

Boh-Ram Kim, Seung Hee Seo, Mi Sun Park, Seung-Hoon Lee, Youngjoo Kwon,  and Seung Bae Rho
31830-31843
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Non-random aneuploidy specifies subgroups of pilocytic astrocytoma and correlates with older age

Non-random aneuploidy specifies subgroups of pilocytic astrocytoma and correlates with older age

https://doi.org/10.18632/oncotarget.5571

Adam M. Fontebasso, Margret Shirinian, Dong-Anh Khuong-Quang, Denise Bechet, Tenzin Gayden, Marcel Kool, Nicolas De Jay, Karine Jacob, Noha Gerges, Barbara Hutter, Huriye Şeker-Cin, Hendrik Witt, Alexandre Montpetit, Sébastien Brunet, Pierre Lepage, Geneviève Bourret, Almos Klekner, László Bognár, Peter Hauser, Miklós Garami, Jean-Pierre Farmer, Jose-Luis Montes, Jeffrey Atkinson, Sally Lambert, Tony Kwan, Andrey Korshunov, Uri Tabori, V. Peter Collins, Steffen Albrecht, Damien Faury, Stefan M. Pfister, Werner Paulus, Martin Hasselblatt, David T.W. Jones,  and Nada Jabado
31844-31856
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Chaperone gp96 mediates ER-α36 cell membrane expression

Chaperone gp96 mediates ER-α36 cell membrane expression

https://doi.org/10.18632/oncotarget.5273

Junwei Hou, Mengmeng Deng, Xin Li, Weiwei Liu, Xiaoyu Chu, Jing Wang, Feng Chen,  and Songdong Meng
31857-31867
Abstract  |  PDF  |  HTML  |  Order a Reprint

EPHA4 is overexpressed but not functionally active in Sézary syndrome

EPHA4 is overexpressed but not functionally active in Sézary syndrome

https://doi.org/10.18632/oncotarget.5573

Liesbeth Hameetman, Leslie van der Fits, Willem H. Zoutman, Jacoba J. Out-Luiting, Gregg Siegal, Iwan J.P. de Esch, Maarten H. Vermeer,  and Cornelis P. Tensen
31868-31876
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Rapamycin and WYE-354 suppress human gallbladder cancer xenografts in mice

Rapamycin and WYE-354 suppress human gallbladder cancer xenografts in mice

https://doi.org/10.18632/oncotarget.5047

Helga Weber, Pamela Leal, Stefan Stein, Hana Kunkel, Patricia García, Carolina Bizama, Jaime A. Espinoza, Ismael Riquelme, Bruno Nervi, Juan C. Araya, Manuel Grez,  and Juan C. Roa
31877-31888
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Functional osteoclastogenesis: the baseline variability in blood donor precursors is not associated with age and gender

Functional osteoclastogenesis: the baseline variability in blood donor precursors is not associated with age and gender

https://doi.org/10.18632/oncotarget.5575

Eliana Pivetta, Bruna Wassermann, Pietro Bulian, Agostino Steffan, Alfonso Colombatti, Jerry Polesel,  and Paola Spessotto
31889-31900
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

GSK-3β regulates tumor growth and angiogenesis in human glioma cells

GSK-3β regulates tumor growth and angiogenesis in human glioma cells

https://doi.org/10.18632/oncotarget.5043

Peng Zhao, Qi Li, Zhumei Shi, Charlie Li, Lin Wang, Xue Liu, Chengfei Jiang, Xu Qian, Yongping You, Ning Liu, Ling-Zhi Liu, Lianshu Ding,  and Bing-Hua Jiang
31901-31915
Abstract  |  PDF  |  HTML  |  Order a Reprint

Phosphorylation and inactivation of PTEN at residues Ser380/Thr382/383 induced by Helicobacter pylori promotes gastric epithelial cell survival through PI3K/Akt pathway

Phosphorylation and inactivation of PTEN at residues Ser380/Thr382/383 induced by Helicobacter pylori promotes gastric epithelial cell survival through PI3K/Akt pathway

https://doi.org/10.18632/oncotarget.5577

Zhen Yang, Chuan Xie, Wenting Xu, Gongmeizi Liu, Ximei Cao, Wei Li, Jiang Chen, Yin Zhu, Shiwen Luo, Zhijun Luo,  and Nonghua Lu
31916-31926
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

A novel anti-cancer agent Icaritin suppresses hepatocellular carcinoma initiation and malignant growth through the IL-6/Jak2/Stat3 pathway

A novel anti-cancer agent Icaritin suppresses hepatocellular carcinoma initiation and malignant growth through the IL-6/Jak2/Stat3 pathway

https://doi.org/10.18632/oncotarget.5578

Hong Zhao, Yuming Guo, Shu Li, Ruiqin Han, Jianming Ying, Hai Zhu, Yuanyuan Wang, Li Yin, Yuqing Han, Lingzhi Sun, Zhaoyi Wang, Qingcong Lin, Xinyu Bi, Yuchen Jiao, Hongying Jia, Jianjun Zhao, Zhen Huang, Zhiyu Li, Jianguo Zhou, Wei Song, Kun Meng,  and Jianqiang Cai
31927-31943
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

E2F7 overexpression leads to tamoxifen resistance in breast cancer cells by competing with E2F1 at miR-15a/16 promoter

E2F7 overexpression leads to tamoxifen resistance in breast cancer cells by competing with E2F1 at miR-15a/16 promoter

https://doi.org/10.18632/oncotarget.5128

Junjun Chu, Yinghua Zhu, Yujie Liu, Lijuan Sun, Xiaobin Lv, Yanqin Wu, Pengnan Hu, Fengxi Su, Chang Gong, Erwei Song, Bodu Liu,  and Qiang Liu
31944-31957
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

miR675 upregulates long noncoding RNA H19 through activating EGR1 in human liver cancer

miR675 upregulates long noncoding RNA H19 through activating EGR1 in human liver cancer

https://doi.org/10.18632/oncotarget.5579

Haiyan Li, Jiao Li, Song Jia, Mengying Wu, Jiahui An, Qidi Zheng, Wei Zhang,  and Dongdong Lu
31958-31984
Abstract  |  PDF  |  HTML  |  Order a Reprint

The complex metabolic network gearing the G1/S transition in leukemic stem cells: Hints to a rational use of antineoplastic agents

The complex metabolic network gearing the G1/S transition in leukemic stem cells: Hints to a rational use of antineoplastic agents

https://doi.org/10.18632/oncotarget.5155

Theodora Stivarou, Maria Grazia Cipolleschi, Massimo D’Amico, Antonella Mannini, Enrico Mini, Elisabetta Rovida, Persio Dello Sbarba, Massimo Olivotto,  and Ilaria Marzi
31985-31996
Abstract  |  PDF  |  HTML  |  Order a Reprint

Differential regulation of metabolic pathways by androgen receptor (AR) and its constitutively active splice variant, AR-V7, in prostate cancer cells

Differential regulation of metabolic pathways by androgen receptor (AR) and its constitutively active splice variant, AR-V7, in prostate cancer cells

https://doi.org/10.18632/oncotarget.5585

Ayesha A. Shafi, Vasanta Putluri, James M. Arnold, Efrosini Tsouko, Suman Maity, Justin M. Roberts, Cristian Coarfa, Daniel E. Frigo, Nagireddy Putluri, Arun Sreekumar,  and Nancy L. Weigel
31997-32012
Abstract  |  PDF  |  HTML  |  Order a Reprint

Berberine may rescue Fusobacterium nucleatum-induced colorectal tumorigenesis by modulating the tumor microenvironment

Berberine may rescue Fusobacterium nucleatum-induced colorectal tumorigenesis by modulating the tumor microenvironment

https://doi.org/10.18632/oncotarget.5166

Ya-Nan Yu, Ta-Chung Yu, Hui-Jun Zhao, Tian-Tian Sun, Hui-Min Chen, Hao-Yan Chen, Hui-Fang An, Yu-Rong Weng, Jun Yu, Min Li, Wen-Xin Qin, Xiong Ma, Nan Shen, Jie Hong,  and Jing-Yuan Fang
32013-32026
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Role of HER2 mutations in refractory metastatic breast cancers: targeted sequencing results in patients with refractory breast cancer

Role of HER2 mutations in refractory metastatic breast cancers: targeted sequencing results in patients with refractory breast cancer

https://doi.org/10.18632/oncotarget.5184

Yeon Hee Park, Hyun-Tae Shin, Hae Hyun Jung, Yoon-La Choi, TaeJin Ahn, Kyunghee Park, Aeri Lee, In-Gu Do, Ji-Yeon Kim, Jin Seok Ahn, Woong-Yang Park,  and Young-Hyuck Im
32027-32038
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

PI3K/AKT/mTOR and sonic hedgehog pathways cooperate together to inhibit human pancreatic cancer stem cell characteristics and tumor growth

PI3K/AKT/mTOR and sonic hedgehog pathways cooperate together to inhibit human pancreatic cancer stem cell characteristics and tumor growth

https://doi.org/10.18632/oncotarget.5055

Narinder Sharma, Rajesh Nanta, Jay Sharma, Sumedha Gunewardena, Karan P. Singh, Sharmila Shankar,  and Rakesh K. Srivastava
32039-32060
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Expression and function of the TL1A/DR3 axis in chronic lymphocytic leukemia

Expression and function of the TL1A/DR3 axis in chronic lymphocytic leukemia

https://doi.org/10.18632/oncotarget.5201

Chiara Cavallini, Ornella Lovato, Anna Bertolaso, Elisa Zoratti, Giorgio Malpeli, Elda Mimiola, Martina Tinelli, Fiorenza Aprili, Cristina Tecchio, Omar Perbellini, Aldo Scarpa, Alberto Zamò, Marco Antonio Cassatella, Giovanni Pizzolo,  and Maria Teresa Scupoli
32061-32074
Abstract  |  PDF  |  HTML  |  Order a Reprint

HER2-specific immunoligands engaging NKp30 or NKp80 trigger NK-cell-mediated lysis of tumor cells and enhance antibody-dependent cell-mediated cytotoxicity

HER2-specific immunoligands engaging NKp30 or NKp80 trigger NK-cell-mediated lysis of tumor cells and enhance antibody-dependent cell-mediated cytotoxicity

https://doi.org/10.18632/oncotarget.5135

Matthias Peipp, Stefanie Derer, Stefan Lohse, Matthias Staudinger, Katja Klausz, Thomas Valerius, Martin Gramatzki,  and Christian Kellner
32075-32088
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Co-targeting of Bcl-2 and mTOR pathway triggers synergistic apoptosis in BH3 mimetics resistant acute lymphoblastic leukemia

Co-targeting of Bcl-2 and mTOR pathway triggers synergistic apoptosis in BH3 mimetics resistant acute lymphoblastic leukemia

https://doi.org/10.18632/oncotarget.5156

Stefano Iacovelli, Maria Rosaria Ricciardi, Matteo Allegretti, Simone Mirabilii, Roberto Licchetta, Paola Bergamo, Cinzia Rinaldo, Ann Zeuner, Robin Foà, Michele Milella, James A. McCubrey, Alberto M. Martelli,  and Agostino Tafuri
32089-32103
Abstract  |  PDF  |  HTML  |  Order a Reprint

A constitutive active MAPK/ERK pathway due to BRAFV600E positively regulates AHR pathway in PTC

A constitutive active MAPK/ERK pathway due to BRAFV600E positively regulates AHR pathway in PTC

https://doi.org/10.18632/oncotarget.5194

Gianluca Occhi, Susi Barollo, Daniela Regazzo, Loris Bertazza, Francesca Galuppini, Vincenza Guzzardo, Marie Lise Jaffrain-Rea, Federica Vianello, Denis Ciato, Filippo Ceccato, Sara Watutantrige-Fernando, Andrea Bisognin, Stefania Bortoluzzi, Gianmaria Pennelli, Marco Boscaro, Carla Scaroni,  and Caterina Mian
32104-32114
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

miRNA expression patterns in normal breast tissue and invasive breast cancers of BRCA1 and BRCA2 germ-line mutation carriers

miRNA expression patterns in normal breast tissue and invasive breast cancers of BRCA1 and BRCA2 germ-line mutation carriers

https://doi.org/10.18632/oncotarget.5617

Shoko Vos, Farhad Vesuna, Venu Raman, Paul J. van Diest,  and Petra van der Groep
32115-32137
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Amphiregulin activates regulatory T lymphocytes and suppresses CD8+ T cell-mediated anti-tumor response in hepatocellular carcinoma cells

Amphiregulin activates regulatory T lymphocytes and suppresses CD8+ T cell-mediated anti-tumor response in hepatocellular carcinoma cells

https://doi.org/10.18632/oncotarget.5171

Chun-Hui Yuan, Xiao-Ming Sun, Cheng-Liang Zhu, Shao-Ping Liu, Long Wu, Hao Chen, Mao-Hui Feng, Ke Wu,  and Fu-Bing Wang
32138-32153
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Hypoxia-induced endoplasmic reticulum stress characterizes a necrotic phenotype of pancreatic cancer

Hypoxia-induced endoplasmic reticulum stress characterizes a necrotic phenotype of pancreatic cancer

https://doi.org/10.18632/oncotarget.5168

Bo Kong, Tao Cheng, Weiwei Wu, Ivonne Regel, Susanne Raulefs, Helmut Friess, Mert Erkan, Irene Esposito, Jörg Kleeff,  and Christoph W. Michalski
32154-32160
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Computational analysis of the mutations in BAP1, PBRM1 and SETD2 genes reveals the impaired molecular processes in renal cell carcinoma

Computational analysis of the mutations in BAP1, PBRM1 and SETD2 genes reveals the impaired molecular processes in renal cell carcinoma

https://doi.org/10.18632/oncotarget.5147

Francesco Piva, Matteo Giulietti, Giulia Occhipinti, Matteo Santoni, Francesco Massari, Valeria Sotte, Roberto Iacovelli, Luciano Burattini, Daniele Santini, Rodolfo Montironi, Stefano Cascinu,  and Giovanni Principato
32161-32168
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Clinical Research Papers

Neutrophil-to-lymphocyte ratio predicts prostatic carcinoma in men undergoing needle biopsy

Neutrophil-to-lymphocyte ratio predicts prostatic carcinoma in men undergoing needle biopsy

https://doi.org/10.18632/oncotarget.5081

Takashi Kawahara, Sachi Fukui, Kentaro Sakamaki, Yusuke Ito, Hiroki Ito, Naohito Kobayashi, Koji Izumi, Yumiko Yokomizo, Yasuhide Miyoshi, Kazuhide Makiyama, Noboru Nakaigawa, Takeharu Yamanaka, Masahiro Yao, Hiroshi Miyamoto,  and Hiroji Uemura
32169-32176
Abstract  |  PDF  |  HTML  |  Order a Reprint

GOLPH3 is a potential therapeutic target and a prognostic indicator of poor survival in bladder cancer treated by cystectomy

GOLPH3 is a potential therapeutic target and a prognostic indicator of poor survival in bladder cancer treated by cystectomy

https://doi.org/10.18632/oncotarget.4867

Qing Zhang, Junlong Zhuang, Yongming Deng, Xiaozhi Zhao, Bo Tang, Dongwei Yao, Wei Zhao, Cunjie Chang, Qun Lu, Wei Chen, Shiwei Zhang, Changwei Ji, Lin Cao,  and Hongqian Guo
32177-32192
Abstract  |  PDF  |  HTML  |  Order a Reprint

XRCC2 as a predictive biomarker for radioresistance in locally advanced rectal cancer patients undergoing preoperative radiotherapy

XRCC2 as a predictive biomarker for radioresistance in locally advanced rectal cancer patients undergoing preoperative radiotherapy

https://doi.org/10.18632/oncotarget.4975

Chang-Jiang Qin, Xin-Ming Song, Zhi-Hui Chen, Xue-Qun Ren, Kai-Wu Xu, Hong Jing,  and Yu-Long He
32193-32204
Abstract  |  PDF  |  HTML  |  Order a Reprint

A single nucleotide polymorphism in ADIPOQ predicts biochemical recurrence after radical prostatectomy in localized prostate cancer

A single nucleotide polymorphism in ADIPOQ predicts biochemical recurrence after radical prostatectomy in localized prostate cancer

https://doi.org/10.18632/oncotarget.4980

Chengyuan Gu, Yuanyuan Qu, Guiming Zhang, LiJiang Sun, Yao Zhu,  and Dingwei Ye
32205-32211
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Phase II study of docetaxel, cisplatin, and fluorouracil in patients with distantly metastatic penile cancer as first-line chemotherapy

Phase II study of docetaxel, cisplatin, and fluorouracil in patients with distantly metastatic penile cancer as first-line chemotherapy

https://doi.org/10.18632/oncotarget.4802

Sheng Zhang, Yao Zhu,  and Dingwei Ye
32212-32219
Abstract  |  PDF  |  HTML  |  Order a Reprint

Tolerance and dose-volume relationship of intrathoracic stomach irradiation after esophagectomy for patients with thoracic esophageal squamous cell carcinoma

Tolerance and dose-volume relationship of intrathoracic stomach irradiation after esophagectomy for patients with thoracic esophageal squamous cell carcinoma

https://doi.org/10.18632/oncotarget.4730

Qi Liu, Xu-Wei Cai, Xiao-Long Fu, Jun-Chao Chen,  and Jia-Qing Xiang
32220-32227
Abstract  |  PDF  |  HTML  |  Order a Reprint

A phase 1/2 study combining gemcitabine, Pegintron and p53 SLP vaccine in patients with platinum-resistant ovarian cancer

A phase 1/2 study combining gemcitabine, Pegintron and p53 SLP vaccine in patients with platinum-resistant ovarian cancer

https://doi.org/10.18632/oncotarget.4772

Eveline M. Dijkgraaf, Saskia J.A.M. Santegoets, An K.L. Reyners, Renske Goedemans, Hans W. Nijman, Mariëtte I.E. van Poelgeest, Arien R. van Erkel, Vincent T.H.B.M. Smit, Toos A.H.H. Daemen, Jacobus J.M. van der Hoeven, Cornelis J.M. Melief, Marij J.P. Welters, Judith R. Kroep,  and Sjoerd H. van der Burg
32228-32243
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

ABO blood type correlates with survival on prostate cancer vaccine therapy

ABO blood type correlates with survival on prostate cancer vaccine therapy

https://doi.org/10.18632/oncotarget.4993

Saddam M. Muthana, James L. Gulley, James W. Hodge, Jeffrey Schlom,  and Jeffrey C. Gildersleeve
32244-32256
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Dynamic 1H-MRS assessment of brain tumors: a novel approach for differential diagnosis of glioma

Dynamic 1H-MRS assessment of brain tumors: a novel approach for differential diagnosis of glioma

https://doi.org/10.18632/oncotarget.4899

Tong Tong, Zhong Yang, John W. Chen, Jianming Zhu,  and Zhenwei Yao
32257-32265
Abstract  |  PDF  |  HTML  |  Order a Reprint

PAPP-A proteolytic activity enhances IGF bioactivity in ascites from women with ovarian carcinoma

PAPP-A proteolytic activity enhances IGF bioactivity in ascites from women with ovarian carcinoma

https://doi.org/10.18632/oncotarget.5010

Jacob Thomsen, Rikke Hjortebjerg, Ulrick Espelund, Gitte Ørtoft, Poul Vestergaard, Nils E. Magnusson, Cheryl A. Conover, Trine Tramm, Henrik Hager, Claus Høgdall, Estrid Høgdall, Claus Oxvig,  and Jan Frystyk
32266-32278
Abstract  |  PDF  |  HTML  |  Order a Reprint


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