Oncotarget

Vol 6, No 24

August 21, 2015

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See Tseng et al. Bisphosphonate-induced differential modulation of immune cell function in gingiva and bone marrow in vivo; Role in osteoclast-mediated NK cell activation

Table of Contents

Editorial

Targeting splenic hematopoietic stem cells in cardiovascular disease

Targeting splenic hematopoietic stem cells in cardiovascular disease

https://doi.org/10.18632/oncotarget.4918

Matthias Nahrendorf,  and Partha Dutta
19918-19919
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The host cell side of latent HIV-1 infection

The host cell side of latent HIV-1 infection

https://doi.org/10.18632/oncotarget.5101

Lillian Seu,  and Olaf Kutsch
19920-19921
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Platelet signaling - blood’s great balancing act

Platelet signaling - blood’s great balancing act

https://doi.org/10.18632/oncotarget.5122

Wolfgang Bergmeier,  and Lucia Stefanini
19922-19923
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Gamma-carboxylation regulates osteocalcin function

Gamma-carboxylation regulates osteocalcin function

https://doi.org/10.18632/oncotarget.5126

Julie Lacombe,  and Mathieu Ferron
19924-19925
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Arcuate nucleus glucokinase and dietary glucose intake

Arcuate nucleus glucokinase and dietary glucose intake

https://doi.org/10.18632/oncotarget.5138

Yue Ma, Steve R. Bloom,  and James V. Gardiner
19926-19927
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Editorial: Immunology

A new “sweet” ligand for Toll-like receptor 4

A new “sweet” ligand for Toll-like receptor 4

https://doi.org/10.18632/oncotarget.4562

Tomas Deierborg,  and Miguel A. Burguillos
19928-19929
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Deciphering the biology of NKG2C+ Natural Killer cells

Deciphering the biology of NKG2C+ Natural Killer cells

https://doi.org/10.18632/oncotarget.4468

Alexander Rölle
19930-19931
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NK cells in asthma exacerbation

NK cells in asthma exacerbation

https://doi.org/10.18632/oncotarget.4841

Lars Lunding,  and Michael Wegmann
19932-19933
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Immunodeficiency and CARD-BCL10-MALT1

Immunodeficiency and CARD-BCL10-MALT1

https://doi.org/10.18632/oncotarget.4467

Rebeca Pérez de Diego
19934-19935
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GP96: safeguarding Treg

GP96: safeguarding Treg

https://doi.org/10.18632/oncotarget.4582

Yongliang Zhang, Ephraim Ansa-Addo,  and Zihai Li
19936-19937
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The ‘inflammatory’ control of hematopoietic stem cells

The ‘inflammatory’ control of hematopoietic stem cells

https://doi.org/10.18632/oncotarget.4591

Chozha Rathinam
19938-19939
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dsRNA in immunometabolism

dsRNA in immunometabolism

https://doi.org/10.18632/oncotarget.5100

Takahisa Nakamura
19940-19941
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Notch, metabolism and macrophages

Notch, metabolism and macrophages

https://doi.org/10.18632/oncotarget.4651

Jun Xu, Feng Chi,  and Hidekazu Tsukamoto
19942-19943
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Basal body docking in airway ciliated cells

Basal body docking in airway ciliated cells

https://doi.org/10.18632/oncotarget.4609

Feng-Qian Li, Saul S. Siller,  and Ken-Ich Takemaru
19944-19945
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CX3CR1 in multiple sclerosis

CX3CR1 in multiple sclerosis

https://doi.org/10.18632/oncotarget.4650

Serge Rivest
19946-19947
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BTK: sensing pathogenic nucleic acids

BTK: sensing pathogenic nucleic acids

https://doi.org/10.18632/oncotarget.4778

Koon-Guan Lee,  and Kong-Peng Lam
19948-19949
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NLRP12 in autoimmune diseases

NLRP12 in autoimmune diseases

https://doi.org/10.18632/oncotarget.4585

Prajwal Gurung,  and Thirumala-Devi Kanneganti
19950-19951
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Sox5 and Th17 cell differentiation

Sox5 and Th17 cell differentiation

https://doi.org/10.18632/oncotarget.4784

Akira Suto, Shigeru Tanaka,  and Hiroshi Nakajima
19952-19953
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Sec61 in antigen cross-presentation

Sec61 in antigen cross-presentation

https://doi.org/10.18632/oncotarget.4587

Matthias Zehner,  and Sven Burgdorf
19954-19955
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Treg: tolerance vs immunity

Treg: tolerance vs immunity

https://doi.org/10.18632/oncotarget.4648

Moanaro Biswas, Cox Terhorst,  and Roland W. Herzog
19956-19957
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Effector Tregs: middle-men in TGFβ activation

Effector Tregs: middle-men in TGFβ activation

https://doi.org/10.18632/oncotarget.4686

John J. Worthington,  and Mark A. Travis
19958-19959
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IFN type III: in vivo NK cell response

IFN type III: in vivo NK cell response

https://doi.org/10.18632/oncotarget.4758

Fernando Souza-Fonseca-Guimaraes, Arabella Young,  and Mark J. Smyth
19960-19961
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Microbial control of intestinal innate immunity

Microbial control of intestinal innate immunity

https://doi.org/10.18632/oncotarget.4780

Martina Brave, Dana J. Lukin,  and Sridhar Mani
19962-19963
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iCD8α cells: living at the edge of the intestinal immune system

iCD8α cells: living at the edge of the intestinal immune system

https://doi.org/10.18632/oncotarget.4782

Danyvid Olivares-Villagómez,  and Luc Van Kaer
19964-19965
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Self-control for IgE production

Self-control for IgE production

https://doi.org/10.18632/oncotarget.4806

Brice Laffleur,  and Michel Cogné
19966-19967
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Reviews

Reactivating p53 functions by suppressing its novel inhibitor iASPP: a potential therapeutic opportunity in p53 wild-type tumors

Reactivating p53 functions by suppressing its novel inhibitor iASPP: a potential therapeutic opportunity in p53 wild-type tumors

https://doi.org/10.18632/oncotarget.4847

Peixin Dong, Kei Ihira, Junichi Hamada, Hidemichi Watari, Takahiro Yamada, Masayoshi Hosaka, Sharon J.B. Hanley, Masataka Kudo,  and Noriaki Sakuragi
19968-19975
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Going viral: a review of replication-selective oncolytic adenoviruses

Going viral: a review of replication-selective oncolytic adenoviruses

https://doi.org/10.18632/oncotarget.5116

Christopher Larson, Bryan Oronsky, Jan Scicinski, Gary R. Fanger, Meaghan Stirn, Arnold Oronsky,  and Tony R. Reid
19976-19989
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Priority Research Papers

Loss of p53 enhances the function of the endoplasmic reticulum through activation of the IRE1α/XBP1 pathway

Loss of p53 enhances the function of the endoplasmic reticulum through activation of the IRE1α/XBP1 pathway

https://doi.org/10.18632/oncotarget.4598

Takushi Namba, Kiki Chu, Rika Kodama, Sanguine Byun, Kyoung Wan Yoon, Masatsugu Hiraki, Anna Mandinova,  and Sam W. Lee
19990-20001
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Research Papers: Immunology

Bisphosphonate-induced differential modulation of immune cell function in gingiva and bone marrow in vivo: Role in osteoclast-mediated NK cell activation

Bisphosphonate-induced differential modulation of immune cell function in gingiva and bone marrow in vivo: Role in osteoclast-mediated NK cell activation

https://doi.org/10.18632/oncotarget.4755

Han-Ching Tseng, Keiichi Kanayama, Kawaljit Kaur, So-Hyun Park, Sil Park, Anna Kozlowska, Shuting Sun, Charles E. McKenna, Ichiro Nishimura,  and Anahid Jewett
20002-20025
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Helios, and not FoxP3, is the marker of activated Tregs expressing GARP/LAP

Helios, and not FoxP3, is the marker of activated Tregs expressing GARP/LAP

https://doi.org/10.18632/oncotarget.4771

Eyad Elkord, May Abd Al Samid,  and Belal Chaudhary
20026-20036
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A novel human STAT3 mutation presents with autoimmunity involving Th17 hyperactivation

A novel human STAT3 mutation presents with autoimmunity involving Th17 hyperactivation

https://doi.org/10.18632/oncotarget.5042

Judith Wienke, Willemijn Janssen, Rianne Scholman, Hilde Spits, Marielle van Gijn, Marianne Boes, Joris van Montfrans, Nicolette Moes,  and Sytze de Roock
20037-20042
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Survivin co-ordinates formation of follicular T-cells acting in synergy with Bcl-6

Survivin co-ordinates formation of follicular T-cells acting in synergy with Bcl-6

https://doi.org/10.18632/oncotarget.4994

Karin M. E. Andersson, Mikael Brisslert, Nicola Filluelo Cavallini, Mattias N. D. Svensson, Amanda Welin, Malin C. Erlandsson, Michael J. Ciesielski, Gergely Katona,  and Maria I. Bokarewa
20043-20057
Abstract  |  PDF  |  HTML  |  Order a Reprint

Research Papers

CD80-CD28 signaling controls the progression of inflammatory colorectal carcinogenesis

CD80-CD28 signaling controls the progression of inflammatory colorectal carcinogenesis

https://doi.org/10.18632/oncotarget.2780

Marco Scarpa, Paola Brun, Melania Scarpa, Susan Morgan, Andrea Porzionato, Andromachi Kotsafti, Marina Bortolami, Andrea Buda, Renata D’Incà, Veronica Macchi, Giacomo C. Sturniolo, Massimo Rugge, Romeo Bardini, Ignazio Castagliuolo, Imerio Angriman,  and Carlo Castoro
20058-20069
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

MicroRNA-101 inhibits cell progression and increases paclitaxel sensitivity by suppressing MCL-1 expression in human triple-negative breast cancer

MicroRNA-101 inhibits cell progression and increases paclitaxel sensitivity by suppressing MCL-1 expression in human triple-negative breast cancer

https://doi.org/10.18632/oncotarget.4039

Xiaoping Liu, Hailin Tang, Jianping Chen, Cailu Song, Lu Yang, Peng Liu, Neng Wang, Xinhua Xie, Xiaoti Lin,  and Xiaoming Xie
20070-20083
Abstract  |  PDF  |  HTML  |  Order a Reprint

A small-molecule inhibitor suppresses the tumor-associated mitochondrial NAD(P)+-dependent malic enzyme (ME2) and induces cellular senescence

A small-molecule inhibitor suppresses the tumor-associated mitochondrial NAD(P)+-dependent malic enzyme (ME2) and induces cellular senescence

https://doi.org/10.18632/oncotarget.3907

Ju-Yi Hsieh, Shao-Yu Li, Wen-Chen Tsai, Jyung-Hurng Liu, Chih-Li Lin, Guang-Yaw Liu,  and Hui-Chih Hung
20084-20098
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Clinical next generation sequencing to identify actionable aberrations in a phase I program

Clinical next generation sequencing to identify actionable aberrations in a phase I program

https://doi.org/10.18632/oncotarget.4040

Genevieve M. Boland, Sarina A. Piha-Paul, Vivek Subbiah, Mark Routbort, Shelley M. Herbrich, Keith Baggerly, Keyur P. Patel, Lauren Brusco, Chacha Horombe, Aung Naing, Siqing Fu, David S. Hong, Filip Janku, Amber Johnson, Russell Broaddus, Raja Luthra, Kenna Shaw, John Mendelsohn, Gordon B. Mills,  and Funda Meric-Bernstam
20099-20110
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Tanshinones suppress AURKA through up-regulation of miR-32 expression in non-small cell lung cancer

Tanshinones suppress AURKA through up-regulation of miR-32 expression in non-small cell lung cancer

https://doi.org/10.18632/oncotarget.3933

Zhong-Liang Ma, Bing-Jie Zhang, De-Tao Wang, Xue Li, Jia-Li Wei, Bo-Tao Zhao, Yan Jin, Yan-Li Li,  and You-Xin Jin
20111-20120
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

A novel SAHA-bendamustine hybrid induces apoptosis of leukemia cells

A novel SAHA-bendamustine hybrid induces apoptosis of leukemia cells

https://doi.org/10.18632/oncotarget.4041

Jing Yu, Shaowei Qiu, Qiufu Ge, Ying Wang, Hui Wei, Dianwu Guo, Shuying Chen, Shuang Liu, Shouyun Li, Haiyan Xing, Qing Rao, Jianxiang Wang,  and Min Wang
20121-20131
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Combined targeting of EGFR/HER promotes anti-tumor efficacy in subsets of KRAS mutant lung cancer resistant to single EGFR blockade

Combined targeting of EGFR/HER promotes anti-tumor efficacy in subsets of KRAS mutant lung cancer resistant to single EGFR blockade

https://doi.org/10.18632/oncotarget.3853

Ijeoma Adaku Umelo, Olivier De Wever, Peter Kronenberger, Jan Van Deun, Alfiah Noor, Kshitiz Singh, Erik Teugels, Gang Chen, Marc Bracke,  and Jacques De Grève
20132-20144
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

In vivo RNAi screen identifies NLK as a negative regulator of mesenchymal activity in glioblastoma

In vivo RNAi screen identifies NLK as a negative regulator of mesenchymal activity in glioblastoma

https://doi.org/10.18632/oncotarget.3980

Jason K. Sa, Yeup Yoon, Misuk Kim, Yeonghwan Kim, Hee Jin Cho, Jin-Ku Lee, Gi-Soo Kim, Suji Han, Woon Jin Kim, Yong Jae Shin, Kyeung Min Joo, Patrick J. Paddison, Tohru Ishitani, Jeongwu Lee,  and Do-Hyun Nam
20145-20159
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Genomic characterization of a large panel of patient-derived hepatocellular carcinoma xenograft tumor models for preclinical development

Genomic characterization of a large panel of patient-derived hepatocellular carcinoma xenograft tumor models for preclinical development

https://doi.org/10.18632/oncotarget.3969

Qingyang Gu, Bin Zhang, Hongye Sun, Qiang Xu, Yexiong Tan, Guan Wang, Qin Luo, Weiguo Xu, Shuqun Yang, Jian Li, Jing Fu, Lei Chen, Shengxian Yuan, Guibai Liang, Qunsheng Ji, Shu-Hui Chen, Chi-Chung Chan, Weiping Zhou, Xiaowei Xu, Hongyang Wang,  and Douglas D. Fang
20160-20176
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

The 14-3-3σ/GSK3β/β-catenin/ZEB1 regulatory loop modulates chemo-sensitivity in human tongue cancer

The 14-3-3σ/GSK3β/β-catenin/ZEB1 regulatory loop modulates chemo-sensitivity in human tongue cancer

https://doi.org/10.18632/oncotarget.3896

Cong Peng, Xiaoting Jia, Yan Xiong, Jiang Yin, Nan Li, Yingen Deng, Kai Luo, Qiong Zhang, Chengkun Wang, Zhijie Zhang, Guopei Zheng,  and Zhimin He
20177-20189
Abstract  |  PDF  |  HTML  |  Order a Reprint

Overexpression of MAPK15 in gastric cancer is associated with copy number gain and contributes to the stability of c-Jun

Overexpression of MAPK15 in gastric cancer is associated with copy number gain and contributes to the stability of c-Jun

https://doi.org/10.18632/oncotarget.4171

Dong-Hao Jin, Jeeyun Lee, Kyoung Mee Kim, Sung Kim, Duk-Hwan Kim,  and Joobae Park
20190-20203
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

High CD204+ tumor-infiltrating macrophage density predicts a poor prognosis in patients with urothelial cell carcinoma of the bladder

High CD204+ tumor-infiltrating macrophage density predicts a poor prognosis in patients with urothelial cell carcinoma of the bladder

https://doi.org/10.18632/oncotarget.3887

Bo Wang, Hao Liu, Xiaoliang Dong, Shaoxu Wu, Hong Zeng, Zhuowei Liu, Di Wan, Wen Dong, Wang He, Xu Chen, Limin Zheng, Jian Huang,  and Tianxin Lin
20204-20214
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

FGFR2 is overexpressed in myxoid liposarcoma and inhibition of FGFR signaling impairs tumor growth in vitro

FGFR2 is overexpressed in myxoid liposarcoma and inhibition of FGFR signaling impairs tumor growth in vitro

https://doi.org/10.18632/oncotarget.4046

Helen Künstlinger, Jana Fassunke, Hans-Ulrich Schildhaus, Benedikt Brors, Carina Heydt, Michaela Angelika Ihle, Gunhild Mechtersheimer, Eva Wardelmann, Reinhard Büttner,  and Sabine Merkelbach-Bruse
20215-20230
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Efficacy of the polo-like kinase inhibitor rigosertib, alone or in combination with abelson tyrosine kinase inhibitors, against break point cluster region-c-Abelson-positive leukemia cells

Efficacy of the polo-like kinase inhibitor rigosertib, alone or in combination with abelson tyrosine kinase inhibitors, against break point cluster region-c-Abelson-positive leukemia cells

https://doi.org/10.18632/oncotarget.4047

Seiichi Okabe, Tetsuzo Tauchi, Yuko Tanaka, Juri Sakuta,  and Kazuma Ohyashiki
20231-20240
Abstract  |  PDF  |  HTML  |  Order a Reprint

Enhanced antitumor efficacy of ultrasonic cavitation with up-sized microbubbles in pancreatic cancer

Enhanced antitumor efficacy of ultrasonic cavitation with up-sized microbubbles in pancreatic cancer

https://doi.org/10.18632/oncotarget.4048

Pintong Huang, Ying Zhang, Jian Chen, Weihui Shentu, Yu Sun, Zhijian Yang, Tingbo Liang, Shuyuan Chen,  and Zhaoxia Pu
20241-20251
Abstract  |  PDF  |  HTML  |  Order a Reprint

BCL6B expression in hepatocellular carcinoma and its efficacy in the inhibition of liver damage and fibrogenesis

BCL6B expression in hepatocellular carcinoma and its efficacy in the inhibition of liver damage and fibrogenesis

https://doi.org/10.18632/oncotarget.3857

Weilin Wang, Pengfei Huang, Panyisha Wu, Rong Kong, Jiang Xu, Lufei Zhang, Qifan Yang, Qingsong Xie, Linshi Zhang, Xiaohu Zhou, Linhui Chen, Haiyang Xie, Lin Zhou,  and Shusen Zheng
20252-20265
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Mechanism for enhanced 5-aminolevulinic acid fluorescence in isocitrate dehydrogenase 1 mutant malignant gliomas

Mechanism for enhanced 5-aminolevulinic acid fluorescence in isocitrate dehydrogenase 1 mutant malignant gliomas

https://doi.org/10.18632/oncotarget.4060

Ja Eun Kim, Hye Rim Cho, Wen Jun Xu, Ji Young Kim, Sung Kwon Kim, Seung-Ki Kim, Sung-Hye Park, Hyeonjin Kim, Se-Hoon Lee, Seung Hong Choi, Sunghyouk Park,  and Chul-Kee Park
20266-20277
Abstract  |  PDF  |  HTML  |  Order a Reprint

Detecting cell-in-cell structures in human tumor samples by E-cadherin/CD68/CD45 triple staining

Detecting cell-in-cell structures in human tumor samples by E-cadherin/CD68/CD45 triple staining

https://doi.org/10.18632/oncotarget.4275

Hongyan Huang, Ang Chen, Ting Wang, Manna Wang, Xiangkai Ning, Meifang He, Yazhuo Hu, Long Yuan, Shichong Li, Qiwei Wang, Hong Liu, Zhaolie Chen, Jun Ren,  and Qiang Sun
20278-20287
Abstract  |  PDF  |  HTML  |  Order a Reprint

Hypoxia attenuates the proinflammatory response in colon cancer cells by regulating IκB

Hypoxia attenuates the proinflammatory response in colon cancer cells by regulating IκB

https://doi.org/10.18632/oncotarget.3961

Kamila Müller-Edenborn, Karolin Léger, Jesus F. Glaus Garzon, Carole Oertli, Ali Mirsaidi, Peter J. Richards, Hubert Rehrauer, Patrick Spielmann, David Hoogewijs, Lubor Borsig, Michael O. Hottiger,  and Roland H. Wenger
20288-20301
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

The IgH 3’ regulatory region influences lymphomagenesis in Igλ-Myc mice

The IgH 3’ regulatory region influences lymphomagenesis in Igλ-Myc mice

https://doi.org/10.18632/oncotarget.3963

Faten Saad, Alexis Saintamand, Michel Cogné,  and Yves Denizot
20302-20311
Abstract  |  PDF  |  HTML  |  Order a Reprint

Snail and serpinA1 promote tumor progression and predict prognosis in colorectal cancer

Snail and serpinA1 promote tumor progression and predict prognosis in colorectal cancer

https://doi.org/10.18632/oncotarget.3964

Chae Hwa Kwon, Hye Ji Park, Jin Hwa Choi, Ja Rang Lee, Hye Kyung Kim, Hong-jae Jo, Hyun Sung Kim, Nahmgun Oh, Geun Am Song,  and Do Youn Park
20312-20326
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Inflammatory and oncogenic roles of a tumor stem cell marker doublecortin-like kinase (DCLK1) in virus-induced chronic liver diseases

Inflammatory and oncogenic roles of a tumor stem cell marker doublecortin-like kinase (DCLK1) in virus-induced chronic liver diseases

https://doi.org/10.18632/oncotarget.3972

Naushad Ali, Parthasarathy Chandrakesan, Charles B. Nguyen, Sanam Husain, Allison F. Gillaspy, Mark Huycke, William L. Berry, Randal May, Dongfeng Qu, Nathaniel Weygant, Sripathi M. Sureban, Michael S. Bronze, Danny N. Dhanasekaran,  and Courtney W. Houchen
20327-20344
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

A novel oHSV-1 targeting telomerase reverse transcriptase-positive cancer cells via tumor-specific promoters regulating the expression of ICP4

A novel oHSV-1 targeting telomerase reverse transcriptase-positive cancer cells via tumor-specific promoters regulating the expression of ICP4

https://doi.org/10.18632/oncotarget.3884

Wen Zhang, Keli Ge, Qian Zhao, Xiufen Zhuang, Zhenling Deng, Lingling Liu, Jie Li, Yu Zhang, Ying Dong, Youhui Zhang, Shuren Zhang,  and Binlei Liu
20345-20355
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

PC-1/PrLZ confers resistance to rapamycin in prostate cancer cells through increased 4E-BP1 stability

PC-1/PrLZ confers resistance to rapamycin in prostate cancer cells through increased 4E-BP1 stability

https://doi.org/10.18632/oncotarget.3931

Lan yu, Zeng-Fu Shang, Jian Wang, Hongtao Wang, Fang Huang, Zhe Zhang, Ying Wang, Jianguang Zhou,  and Shanhu Li
20356-20369
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Simultaneous inhibition of multiple oncogenic miRNAs by a multi-potent microRNA sponge

Simultaneous inhibition of multiple oncogenic miRNAs by a multi-potent microRNA sponge

https://doi.org/10.18632/oncotarget.4827

Jaeyun Jung, Chanjoo Yeom, Yeon-Sook Choi, Sinae Kim, EunJi Lee, Min Ji Park, Sang Wook Kang, Sung Bae Kim,  and Suhwan Chang
20370-20387
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

ROS1 amplification mediates resistance to gefitinib in glioblastoma cells

ROS1 amplification mediates resistance to gefitinib in glioblastoma cells

https://doi.org/10.18632/oncotarget.3981

Hashim Aljohani, Robert F. Koncar, Ahmad Zarzour, Byung Sun Park, So Ha Lee,  and El Mustapha Bahassi
20388-20395
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Mutated Fanconi anemia pathway in non-Fanconi anemia cancers

Mutated Fanconi anemia pathway in non-Fanconi anemia cancers

https://doi.org/10.18632/oncotarget.4056

Yihang Shen, Yuan-Hao Lee, Jayabal Panneerselvam, Jun Zhang, Lenora W. M. Loo,  and Peiwen Fei
20396-20403
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Upregulated long non-coding RNA AFAP1-AS1 expression is associated with progression and poor prognosis of nasopharyngeal carcinoma

Upregulated long non-coding RNA AFAP1-AS1 expression is associated with progression and poor prognosis of nasopharyngeal carcinoma

https://doi.org/10.18632/oncotarget.4057

Hao Bo, Zhaojian Gong, Wenling Zhang, Xiayu Li, Yong Zeng, Qianjin Liao, Pan Chen, Lei Shi, Yu Lian, Yizhou Jing, Ke Tang, Zheng Li, Yanhong Zhou, Ming Zhou, Bo Xiang, Xiaoling Li, Jianbo Yang, Wei Xiong, Guiyuan Li,  and Zhaoyang Zeng
20404-20418
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

The prognostic potential and oncogenic effects of PRR11 expression in hilar cholangiocarcinoma

The prognostic potential and oncogenic effects of PRR11 expression in hilar cholangiocarcinoma

https://doi.org/10.18632/oncotarget.3983

Ying Chen, Zhanshan Cha, Wenzheng Fang, Baohua Qian, Wenlong Yu, Wenfeng Li, Guanzhen Yu,  and Yong Gao
20419-20433
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Overexpression of microRNA-95-3p suppresses brain metastasis of lung adenocarcinoma through downregulation of cyclin D1

Overexpression of microRNA-95-3p suppresses brain metastasis of lung adenocarcinoma through downregulation of cyclin D1

https://doi.org/10.18632/oncotarget.3886

Su Jin Hwang, Hye Won Lee, Hye Ree Kim, Hye Jin Song, Dong Heon Lee, Hong Lee, Chang Hoon Shin, Je-Gun Joung, Duk-Hwan Kim, Kyeung Min Joo,  and Hyeon Ho Kim
20434-20448
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Epigenetically downregulated Semaphorin 3E contributes to gastric cancer

Epigenetically downregulated Semaphorin 3E contributes to gastric cancer

https://doi.org/10.18632/oncotarget.3936

Hui Chen, Guo-Hua Xie, Wei-Wei Wang, Xiang-Liang Yuan, Wen-Ming Xing, Hong-Jing Liu, Jin Chen, Min Dou,  and Li-Song Shen
20449-20465
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Highly sensitive and quantitative evaluation of the EGFR T790M mutation by nanofluidic digital PCR

Highly sensitive and quantitative evaluation of the EGFR T790M mutation by nanofluidic digital PCR

https://doi.org/10.18632/oncotarget.4058

Eiji Iwama, Koichi Takayama, Taishi Harada, Isamu Okamoto, Fumihiko Ookubo, Junji Kishimoto, Eishi Baba, Yoshinao Oda,  and Yoichi Nakanishi
20466-20473
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Catalytic inhibitors of DNA topoisomerase II suppress the androgen receptor signaling and prostate cancer progression

Catalytic inhibitors of DNA topoisomerase II suppress the androgen receptor signaling and prostate cancer progression

https://doi.org/10.18632/oncotarget.4105

Haolong Li, Ning Xie, Martin E. Gleave,  and Xuesen Dong
20474-20484
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

CCL18-mediated down-regulation of miR98 and miR27b promotes breast cancer metastasis

CCL18-mediated down-regulation of miR98 and miR27b promotes breast cancer metastasis

https://doi.org/10.18632/oncotarget.4107

Xiaorong Lin, Lijun Chen, Yandang Yao, Ruihua Zhao, Xiuying Cui, Jun Chen, Kailian Hou, Mingxia Zhang, Fengxi Su, Jingqi Chen,  and Erwei Song
20485-20499
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Tumorigenesis and peritoneal colonization from fallopian tube epithelium

Tumorigenesis and peritoneal colonization from fallopian tube epithelium

https://doi.org/10.18632/oncotarget.3985

Sharon L. Eddie, Suzanne M. Quartuccio, Eoghainin Ó hAinmhire, Georgette Moyle-Heyrman, Dan D. Lantvit, Jian-Jun Wei, Barbara C. Vanderhyden,  and Joanna E. Burdette
20500-20512
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An increase in glucosylceramide synthase induces Bcl-xL-mediated cell survival in vinorelbine-resistant lung adenocarcinoma cells

An increase in glucosylceramide synthase induces Bcl-xL-mediated cell survival in vinorelbine-resistant lung adenocarcinoma cells

https://doi.org/10.18632/oncotarget.4109

Wei-Hsin Chiu, Wu-Chou Su, Chia-Ling Li, Chia-Ling Chen,  and Chiou-Feng Lin
20513-20524
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Type II transglutaminase stimulates epidermal cancer stem cell epithelial-mesenchymal transition

Type II transglutaminase stimulates epidermal cancer stem cell epithelial-mesenchymal transition

https://doi.org/10.18632/oncotarget.3890

Matthew L. Fisher, Gautam Adhikary, Wen Xu, Candace Kerr, Jeffrey W. Keillor,  and Richard L. Eckert
20525-20539
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Dragon (repulsive guidance molecule b, RGMb) is a novel gene that promotes colorectal cancer growth

Dragon (repulsive guidance molecule b, RGMb) is a novel gene that promotes colorectal cancer growth

https://doi.org/10.18632/oncotarget.4110

Ying Shi, Guo-Bin Chen, Xiao-Xiao Huang, Chuan-Xing Xiao, Huan-Huan Wang, Ye-Sen Li, Jin-Fang Zhang, Shao Li, Yin Xia, Jian-Lin Ren,  and Bayasi Guleng
20540-20554
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Jak3, STAT3, and STAT5 inhibit expression of miR-22, a novel tumor suppressor microRNA, in cutaneous T-Cell lymphoma

Jak3, STAT3, and STAT5 inhibit expression of miR-22, a novel tumor suppressor microRNA, in cutaneous T-Cell lymphoma

https://doi.org/10.18632/oncotarget.4111

Nina A. Sibbesen, Katharina L. Kopp, Ivan V. Litvinov, Lars Jønson, Andreas Willerslev-Olsen, Simon Fredholm, David L. Petersen, Claudia Nastasi, Thorbjørn Krejsgaard, Lise M. Lindahl, Robert Gniadecki, Nigel P. Mongan, Denis Sasseville, Mariusz A. Wasik, Lars Iversen, Charlotte M. Bonefeld, Carsten Geisler, Anders Woetmann,  and Niels Odum
20555-20569
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Inhibition of RSK with the novel small-molecule inhibitor LJI308 overcomes chemoresistance by eliminating cancer stem cells

Inhibition of RSK with the novel small-molecule inhibitor LJI308 overcomes chemoresistance by eliminating cancer stem cells

https://doi.org/10.18632/oncotarget.4135

Alastair H. Davies, Kristen Reipas, Kaiji Hu, Rachel Berns, Natalie Firmino, Anna L. Stratford,  and Sandra E. Dunn
20570-20577
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Acetylation at lysine 71 inactivates superoxide dismutase 1 and sensitizes cancer cells to genotoxic agents

Acetylation at lysine 71 inactivates superoxide dismutase 1 and sensitizes cancer cells to genotoxic agents

https://doi.org/10.18632/oncotarget.3987

Chenchu Lin, Hanlin Zeng, Junyan Lu, Zuoquan Xie, Wenyi Sun, Cheng Luo, Jian Ding, Shengtao Yuan, Meiyu Geng,  and Min Huang
20578-20591
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Circulating and tumor-infiltrating Tim-3 in patients with colorectal cancer

Circulating and tumor-infiltrating Tim-3 in patients with colorectal cancer

https://doi.org/10.18632/oncotarget.4112

Benling Xu, Long Yuan, Quanli Gao, Peng Yuan, Peng Zhao, Huijuan Yuan, Huijie Fan, Tiepeng Li, Peng Qin, Lu Han, Weijia Fang,  and Zhenhe Suo
20592-20603
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

The LPA1/ZEB1/miR-21-activation pathway regulates metastasis in basal breast cancer

The LPA1/ZEB1/miR-21-activation pathway regulates metastasis in basal breast cancer

https://doi.org/10.18632/oncotarget.3774

Debashish Sahay, Raphael Leblanc, Thomas G.P. Grunewald, Srikant Ambatipudi, Johnny Ribeiro, Philippe Clézardin,  and Olivier Peyruchaud
20604-20620
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Increased resistance to proteasome inhibitors in multiple myeloma mediated by cIAP2 - implications for a combinatorial treatment

Increased resistance to proteasome inhibitors in multiple myeloma mediated by cIAP2 - implications for a combinatorial treatment

https://doi.org/10.18632/oncotarget.4139

Charlotte Fristedt Duvefelt, Susanne Lub, Prasoon Agarwal, Linda Arngården, Anna Hammarberg, Ken Maes, Els Van Valckenborgh, Karin Vanderkerken,  and Helena Jernberg Wiklund
20621-20635
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Insulin-like growth factor binding protein 5 (IGFBP5) functions as a tumor suppressor in human melanoma cells

Insulin-like growth factor binding protein 5 (IGFBP5) functions as a tumor suppressor in human melanoma cells

https://doi.org/10.18632/oncotarget.4114

Junyun Wang, Nan Ding, Yongjun Li, Hua Cheng, Dong Wang, Qiong Yang, Youhui Deng, Yaran Yang, Yanming Li, Xiuyan Ruan, Fang Xie, Hua Zhao,  and Xiangdong Fang
20636-20649
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Mutation of N-linked glycosylation at Asn548 in CD133 decreases its ability to promote hepatoma cell growth

Mutation of N-linked glycosylation at Asn548 in CD133 decreases its ability to promote hepatoma cell growth

https://doi.org/10.18632/oncotarget.4115

Ying Liu, Shifang Ren, Liqi Xie, Chunhong Cui, Yang Xing, Chanjuan Liu, Benjin Cao, Fan Yang, Yinan Li, Xiaoning Chen, Yuanyan Wei, Haojie Lu,  and Jianhai Jiang
20650-20660
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

RNA sequencing reveals differentially expressed genes as potential diagnostic and prognostic indicators of gallbladder carcinoma

RNA sequencing reveals differentially expressed genes as potential diagnostic and prognostic indicators of gallbladder carcinoma

https://doi.org/10.18632/oncotarget.3861

Xing Gu, Bin Li, Mingming Jiang, Meng Fang, Jun Ji, Aihua Wang, Mengmeng Wang, Xiaoqing Jiang,  and Chunfang Gao
20661-20671
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Identification of the interplay between SOX9 and S100P in the metastasis and invasion of colon carcinoma

Identification of the interplay between SOX9 and S100P in the metastasis and invasion of colon carcinoma

https://doi.org/10.18632/oncotarget.3967

Zhiyong Shen, Haijun Deng, Yuan Fang, Xianjun Zhu, Geng-tai Ye, Li Yan, Hao Liu,  and Guoxin Li
20672-20684
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

CUEDC2 down-regulation is associated with tumor growth and poor prognosis in lung adenocarcinoma

CUEDC2 down-regulation is associated with tumor growth and poor prognosis in lung adenocarcinoma

https://doi.org/10.18632/oncotarget.3930

Longhua Sun, Lihong Bai, Gengpeng Lin, Rang Wang, Yangli Liu, Jinghuang Cai, Yubiao Guo, Zhiwen Zhu,  and Canmao Xie
20685-20696
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

AF1q is a novel TCF7 co-factor which activates CD44 and promotes breast cancer metastasis

AF1q is a novel TCF7 co-factor which activates CD44 and promotes breast cancer metastasis

https://doi.org/10.18632/oncotarget.4136

Jino Park, Michaela Schlederer, Martin Schreiber, Ryan Ice, Olaf Merkel, Martin Bilban, Sebastian Hofbauer, Soojin Kim, Joseph Addison, Jie Zou, Chunyan Ji, Silvia T. Bunting, Zhengqi Wang, Menachem Shoham, Gang Huang, Zsuzsanna Bago-Horvath, Laura F. Gibson, Yon Rojanasakul, Scot Remick, Alexey Ivanov, Elena Pugacheva, Kevin D. Bunting, Richard Moriggl, Lukas Kenner,  and William Tse
20697-20710
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SOX9, a potential tumor suppressor in cervical cancer, transactivates p21WAF1/CIP1 and suppresses cervical tumor growth

SOX9, a potential tumor suppressor in cervical cancer, transactivates p21WAF1/CIP1 and suppresses cervical tumor growth

https://doi.org/10.18632/oncotarget.4133

Hai-yan Wang, Ping Lian,  and Peng-Sheng Zheng
20711-20722
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Hypoxia promotes colon cancer dissemination through up-regulation of cell migration-inducing protein (CEMIP)

Hypoxia promotes colon cancer dissemination through up-regulation of cell migration-inducing protein (CEMIP)

https://doi.org/10.18632/oncotarget.3978

Nikki A. Evensen, Yiyi Li, Cem Kuscu, Jingxuan Liu, Jillian Cathcart, Anna Banach, Qian Zhang, Ellen Li, Sonia Joshi, Jie Yang, Paula I. Denoya, Silvia Pastorekova, Stanley Zucker, Kenneth R. Shroyer,  and Jian Cao
20723-20739
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