Oncotarget

Vol 6, No 22

August 7, 2015

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About The Cover

Representative high and low staining immunofluorescent microscopy images for each marker. LC = loading control (β-actin), DAPI = nuclear stain, CK = cytokeratin (epithelial tumor stain). See Beck et al.

Table of Contents

Editorial

Mastl/PP2A regulate Cdk1 in ooycte maturation

Mastl/PP2A regulate Cdk1 in ooycte maturation

https://doi.org/10.18632/oncotarget.4916

Deepak Adhikari, Kui Liu,  and Philipp Kaldis
18734-18735
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FPRs: linking innate immune system and fibrosis

FPRs: linking innate immune system and fibrosis

https://doi.org/10.18632/oncotarget.4915

Francesca Wanda Rossi,  and Nunzia Montuori
18736-18737
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Scribble dictates orderly stem cell fate

Scribble dictates orderly stem cell fate

https://doi.org/10.18632/oncotarget.4923

Ryo Fujita, Daiki Seko,  and Yusuke Ono
18738-18739
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Fragments and hot spots in drug discovery

Fragments and hot spots in drug discovery

https://doi.org/10.18632/oncotarget.4968

Sandor Vajda, Adrian Whitty,  and Dima Kozakov
18740-18741
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Editorial: Chromosome

A bacterial toxin that cleaves Ras oncoprotein

A bacterial toxin that cleaves Ras oncoprotein

https://doi.org/10.18632/oncotarget.5113

Marco Biancucci,  and Karla J.F. Satchell
18742-18743
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Antimicrobial peptides targeting bacterial ribosome

Antimicrobial peptides targeting bacterial ribosome

https://doi.org/10.18632/oncotarget.5114

Ivan B. Lomakin, Matthieu G. Gagnon,  and Thomas A. Steitz
18744-18745
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Unexpected insights for anti-EGFR cancer therapy

Unexpected insights for anti-EGFR cancer therapy

https://doi.org/10.18632/oncotarget.5115

Philippe Depeille, Robert S. Warren,  and Jeroen P. Roose
18746-18747
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Reviews

Targeting cancer by binding iron: Dissecting cellular signaling pathways

Targeting cancer by binding iron: Dissecting cellular signaling pathways

https://doi.org/10.18632/oncotarget.4349

Goldie Y.L. Lui, Zaklina Kovacevic, Vera Richardson, Angelica M. Merlot, Danuta S. Kalinowski,  and Des R. Richardson
18748-18779
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Priority Research Papers

MYC-repressed long noncoding RNAs antagonize MYC-induced cell proliferation and cell cycle progression

MYC-repressed long noncoding RNAs antagonize MYC-induced cell proliferation and cell cycle progression

https://doi.org/10.18632/oncotarget.3909

Taewan Kim, Ri Cui, Young-Jun Jeon, Paolo Fadda, Hansjuerg Alder,  and Carlo M. Croce
18780-18789
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Research Papers: Gerotarget (Focus on Aging)

Bmk-1 regulates lifespan in Caenorhabditis elegans by activating hsp-16

Bmk-1 regulates lifespan in Caenorhabditis elegans by activating hsp-16

https://doi.org/10.18632/oncotarget.4618

Hong Qian, Xiangru Xu,  and Laura E. Niklason
18790-18799
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Differential modulation of AMPK/PPARα/UCP2 axis in relation to hypertension and aging in the brain, kidneys and heart of two closely related spontaneously hypertensive rat strains

Differential modulation of AMPK/PPARα/UCP2 axis in relation to hypertension and aging in the brain, kidneys and heart of two closely related spontaneously hypertensive rat strains

https://doi.org/10.18632/oncotarget.4033

Speranza Rubattu, Franca Bianchi, Carla Letizia Busceti, Maria Cotugno, Rosita Stanzione, Simona Marchitti, Sara Di Castro, Michele Madonna, Ferdinando Nicoletti,  and Massimo Volpe
18800-18818
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Research Papers: Pathology

Evidence for the involvement of sphingosine-1-phosphate in the homing and engraftment of hematopoietic stem cells to bone marrow

Evidence for the involvement of sphingosine-1-phosphate in the homing and engraftment of hematopoietic stem cells to bone marrow

https://doi.org/10.18632/oncotarget.4710

Mateusz Adamiak, Sylwia Borkowska, Marcin Wysoczynski, Malwina Suszynska, Magda Kucia, Gregg Rokosh, Ahmed Abdel-Latif, Janina Ratajczak,  and Mariusz Z. Ratajczak
18819-18828
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Inhibition of microRNA-497 ameliorates anoxia/reoxygenation injury in cardiomyocytes by suppressing cell apoptosis and enhancing autophagy

Inhibition of microRNA-497 ameliorates anoxia/reoxygenation injury in cardiomyocytes by suppressing cell apoptosis and enhancing autophagy

https://doi.org/10.18632/oncotarget.4774

Xixian Li, Zhi Zeng, Qingman Li, Qiulin Xu, Jiahe Xie, Huixin Hao, Guangjin Luo, Wangjun Liao, Jianping Bin, Xiaobo Huang,  and Yulin Liao
18829-18844
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Research Papers: Chromosome

Integration of microarray analysis into the clinical diagnosis of hematological malignancies: How much can we improve cytogenetic testing?

Integration of microarray analysis into the clinical diagnosis of hematological malignancies: How much can we improve cytogenetic testing?

https://doi.org/10.18632/oncotarget.4586

Jess F. Peterson, Nidhi Aggarwal, Clayton A. Smith, Susanne M. Gollin, Urvashi Surti, Aleksandar Rajkovic, Steven H. Swerdlow,  and Svetlana A. Yatsenko
18845-18862
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Research Papers

Phospho-T356RB1 predicts survival in HPV-negative squamous cell carcinoma of the head and neck

Phospho-T356RB1 predicts survival in HPV-negative squamous cell carcinoma of the head and neck

https://doi.org/10.18632/oncotarget.4321

Tim N. Beck, John Kaczmar, Elizabeth Handorf, Anna Nikonova, Cara Dubyk, Suraj Peri, Miriam Lango, John A. Ridge, Ilya G. Serebriiskii, Barbara Burtness, Erica A. Golemis,  and Ranee Mehra
18863-18874
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The PARP inhibitor olaparib enhances the sensitivity of Ewing sarcoma to trabectedin

The PARP inhibitor olaparib enhances the sensitivity of Ewing sarcoma to trabectedin

https://doi.org/10.18632/oncotarget.4303

José Luis Ordóñez, Ana Teresa Amaral, Angel M. Carcaboso, David Herrero-Martín, María del Carmen García-Macías, Vicky Sevillano, Diego Alonso, Guillem Pascual-Pasto, Laura San-Segundo, Monica Vila-Ubach, Telmo Rodrigues, Susana Fraile, Cristina Teodosio, Agustín Mayo-Iscar, Miguel Aracil, Carlos María Galmarini, Oscar M. Tirado, Jaume Mora,  and Enrique de Álava
18875-18890
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Increased expression of fatty acid synthase provides a survival advantage to colorectal cancer cells via upregulation of cellular respiration

Increased expression of fatty acid synthase provides a survival advantage to colorectal cancer cells via upregulation of cellular respiration

https://doi.org/10.18632/oncotarget.3783

Yekaterina Y. Zaytseva, Jennifer W. Harris, Mihail I. Mitov, Ji Tae Kim, D. Allan Butterfield, Eun Y. Lee, Heidi L. Weiss, Tianyan Gao,  and B. Mark Evers
18891-18904
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Underexpression of LKB1 tumor suppressor is associated with enhanced Wnt signaling and malignant characteristics of human intrahepatic cholangiocarcinoma

Underexpression of LKB1 tumor suppressor is associated with enhanced Wnt signaling and malignant characteristics of human intrahepatic cholangiocarcinoma

https://doi.org/10.18632/oncotarget.4305

Jinghan Wang, Keqiang Zhang, Jinhui Wang, Xiwei Wu, Xiyong Liu, Bin Li, Yan Zhu, Yong Yu, Qingbao Cheng, Zhenli Hu, Chao Guo, Shuya Hu, Bing Mu, Chun-Hao Tsai, Jie Li, Lynne Smith, Lu Yang, Qi Liu, Peiguo Chu, Vincent Chang, Baihe Zhang, Mengchao Wu, Xiaoqing Jiang,  and Yun Yen
18905-18920
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Small molecule inhibitor screen identifies synergistic activity of the bromodomain inhibitor CPI203 and bortezomib in drug resistant myeloma

Small molecule inhibitor screen identifies synergistic activity of the bromodomain inhibitor CPI203 and bortezomib in drug resistant myeloma

https://doi.org/10.18632/oncotarget.4214

Matthew B. Siegel, Selina Qiuying Liu, Monika A. Davare, Stephen E. Spurgeon, Marc M. Loriaux, Brian J. Druker, Emma C. Scott,  and Jeffrey W. Tyner
18921-18932
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

microRNA-4717 differentially interacts with its polymorphic target in the PD1 3’ untranslated region: A mechanism for regulating PD-1 expression and function in HBV-associated liver diseases

microRNA-4717 differentially interacts with its polymorphic target in the PD1 3’ untranslated region: A mechanism for regulating PD-1 expression and function in HBV-associated liver diseases

https://doi.org/10.18632/oncotarget.3662

Guoyu Zhang, Na Li, Zhu Li, Qianqian Zhu, Fang Li, Cuiling Yang, Qunying Han, Yi Lv, Zhihua Zhou,  and Zhengwen Liu
18933-18944
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Impact of systemic targeted agents on the clinical outcomes of patients with brain metastases

Impact of systemic targeted agents on the clinical outcomes of patients with brain metastases

https://doi.org/10.18632/oncotarget.4153

Adam G. Johnson, Jimmy Ruiz, Ryan Hughes, Brandi R. Page, Scott Isom, John T. Lucas, Emory R. McTyre, Kristin W. Houseknecht, Diandra N. Ayala-Peacock, J. Daniel Bourland, William H. Hinson, Adrian W. Laxton, Stephen B. Tatter, Waldemar Debinski, Kounosuke Watabe,  and Michael D. Chan
18945-18955
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Targeting IRAK1 in T-cell acute lymphoblastic leukemia

Targeting IRAK1 in T-cell acute lymphoblastic leukemia

https://doi.org/10.18632/oncotarget.4150

Charles Dussiau, Amélie Trinquand, Ludovic Lhermitte, Mehdi Latiri, Mathieu Simonin, Agata Cieslak, Nawel Bedjaoui, Patrick Villarèse, Els Verhoeyen, Hervé Dombret, Norbert Ifrah, Elizabeth Macintyre,  and Vahid Asnafi
18956-18965
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Role and prognostic significance of the epithelial-mesenchymal transition factor ZEB2 in ovarian cancer

Role and prognostic significance of the epithelial-mesenchymal transition factor ZEB2 in ovarian cancer

https://doi.org/10.18632/oncotarget.3943

Silvia Prislei, Enrica Martinelli, Gian Franco Zannoni, Marco Petrillo, Flavia Filippetti, Marisa Mariani, Simona Mozzetti, Giuseppina Raspaglio, Giovanni Scambia,  and Cristiano Ferlini
18966-18979
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

MicroRNA-106b inhibits osteoclastogenesis and osteolysis by targeting RANKL in giant cell tumor of bone

MicroRNA-106b inhibits osteoclastogenesis and osteolysis by targeting RANKL in giant cell tumor of bone

https://doi.org/10.18632/oncotarget.4223

Ting Wang, Huabin Yin, Jing Wang, Zhenxi Li, Haifeng Wei, Zhi’an Liu, Zhipeng Wu, Wangjun Yan, Tielong Liu, Dianwen Song, Xinghai Yang, Quan Huang, Wang Zhou,  and Jianru Xiao
18980-18996
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

The predictive value of ERCC1 and p53 for the effect of panobinostat and cisplatin combination treatment in NSCLC

The predictive value of ERCC1 and p53 for the effect of panobinostat and cisplatin combination treatment in NSCLC

https://doi.org/10.18632/oncotarget.3620

Yang Cai, Xiang Yan, Guoqing Zhang, Weihong Zhao,  and Shunchang Jiao
18997-19005
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

miR-17 regulates melanoma cell motility by inhibiting the translation of ETV1

miR-17 regulates melanoma cell motility by inhibiting the translation of ETV1

https://doi.org/10.18632/oncotarget.4147

Ronit Cohen, Eyal Greenberg, Yael Nemlich, Jacob Schachter,  and Gal Markel
19006-19016
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SNP interactions of Helicobacter pylori-related host genes PGC, PTPN11, IL1B, and TLR4 in susceptibility to gastric carcinogenesis

SNP interactions of Helicobacter pylori-related host genes PGC, PTPN11, IL1B, and TLR4 in susceptibility to gastric carcinogenesis

https://doi.org/10.18632/oncotarget.4231

Caiyun He, Huakang Tu, Liping Sun, Qian Xu, Yuehua Gong, Jingjing Jing, Nannan Dong,  and Yuan Yuan
19017-19026
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Nitroxoline impairs tumor progression in vitro and in vivo by regulating cathepsin B activity

Nitroxoline impairs tumor progression in vitro and in vivo by regulating cathepsin B activity

https://doi.org/10.18632/oncotarget.3699

Bojana Mirković, Boštjan Markelc, Miha Butinar, Ana Mitrović, Izidor Sosič, Stanislav Gobec, Olga Vasiljeva, Boris Turk, Maja Čemažar, Gregor Serša,  and Janko Kos
19027-19042
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

miR-1238 inhibits cell proliferation by targeting LHX2 in non-small cell lung cancer

miR-1238 inhibits cell proliferation by targeting LHX2 in non-small cell lung cancer

https://doi.org/10.18632/oncotarget.4232

Xiangguang Shi, Lei Zhan, Can Xiao, Zhe Lei, Haiping Yang, Longqiang Wang, Jun Zhao,  and Hong-Tao Zhang
19043-19054
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

12 overexpressed in hepatocellular carcinoma reduces microRNA-122 expression via HNF4α inactivation, which causes c-Met induction

12 overexpressed in hepatocellular carcinoma reduces microRNA-122 expression via HNF4α inactivation, which causes c-Met induction

https://doi.org/10.18632/oncotarget.3957

Yoon Mee Yang, Chan Gyu Lee, Ja Hyun Koo, Tae Kim Kim, Jung Min Lee, Jihyun An, Kang Mo Kim,  and Sang Geon Kim
19055-19069
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Identification and characterization of the gene expression profiles for protein coding and non-coding RNAs of pancreatic ductal adenocarcinomas

Identification and characterization of the gene expression profiles for protein coding and non-coding RNAs of pancreatic ductal adenocarcinomas

https://doi.org/10.18632/oncotarget.4233

María Laura Gutiérrez, Luis Corchete, Cristina Teodosio, María Eugenia Sarasquete, María del Mar Abad, Manuel Iglesias, Carmen Esteban, José María Sayagues, Alberto Orfao,  and Luis Muñoz-Bellvis
19070-19086
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

A novel HMGA1-CCNE2-YAP axis regulates breast cancer aggressiveness

A novel HMGA1-CCNE2-YAP axis regulates breast cancer aggressiveness

https://doi.org/10.18632/oncotarget.4236

Silvia Pegoraro, Gloria Ros, Yari Ciani, Riccardo Sgarra, Silvano Piazza,  and Guidalberto Manfioletti
19087-19101
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

The SIRT1/TP53 axis is activated upon B-cell receptor triggering via miR-132 up-regulation in chronic lymphocytic leukemia cells

The SIRT1/TP53 axis is activated upon B-cell receptor triggering via miR-132 up-regulation in chronic lymphocytic leukemia cells

https://doi.org/10.18632/oncotarget.3905

Michele Dal Bo, Tiziana D’Agaro, Stefania Gobessi, Antonella Zucchetto, Sara Dereani, Davide Rossi, Francesco Zaja, Gabriele Pozzato, Francesco Di Raimondo, Gianluca Gaidano, Luca Laurenti, Giovanni Del Poeta, Dimitar G. Efremov, Valter Gattei,  and Riccardo Bomben
19102-19117
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

MUC16-mediated activation of mTOR and c-Myc reprograms pancreatic cancer metabolism

MUC16-mediated activation of mTOR and c-Myc reprograms pancreatic cancer metabolism

https://doi.org/10.18632/oncotarget.4078

Surendra K. Shukla, Venugopal Gunda, Jaime Abrego, Dhanya Haridas, Anusha Mishra, Joshua Souchek, Nina V. Chaika, Fang Yu, Aaron R. Sasson, Audrey J. Lazenby, Surinder K. Batra,  and Pankaj K. Singh
19118-19131
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Integrated analysis of microRNAs, transcription factors and target genes expression discloses a specific molecular architecture of hyperdiploid multiple myeloma

Integrated analysis of microRNAs, transcription factors and target genes expression discloses a specific molecular architecture of hyperdiploid multiple myeloma

https://doi.org/10.18632/oncotarget.4302

Maria Teresa Di Martino, Pietro Hiram Guzzi, Daniele Caracciolo, Luca Agnelli, Antonino Neri, Brian A. Walker, Gareth J. Morgan, Mario Cannataro, Pierfrancesco Tassone,  and Pierosandro Tagliaferri
19132-19147
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Protein phosphatase PHLPP induces cell apoptosis and exerts anticancer activity by inhibiting Survivin phosphorylation and nuclear export in gallbladder cancer

Protein phosphatase PHLPP induces cell apoptosis and exerts anticancer activity by inhibiting Survivin phosphorylation and nuclear export in gallbladder cancer

https://doi.org/10.18632/oncotarget.3721

Yinghe Qiu, Xiaoya Li, Bin Yi, Junnian Zheng, Zhangxiao Peng, Zhihan Zhang, Mengchao Wu, Feng Shen,  and Changqing Su
19148-19162
Abstract  |  PDF  |  HTML  |  Order a Reprint

Continuous representation of tumor microvessel density and detection of angiogenic hotspots in histological whole-slide images

Continuous representation of tumor microvessel density and detection of angiogenic hotspots in histological whole-slide images

https://doi.org/10.18632/oncotarget.4383

Jakob Nikolas Kather, Alexander Marx, Constantino Carlos Reyes-Aldasoro, Lothar R. Schad, Frank Gerrit Zöllner,  and Cleo-Aron Weis
19163-19176
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Targeting lactate transport suppresses in vivo breast tumour growth

Targeting lactate transport suppresses in vivo breast tumour growth

https://doi.org/10.18632/oncotarget.3910

Filipa Morais-Santos, Sara Granja, Vera Miranda-Gonçalves, António H.J. Moreira, Sandro Queirós, João L. Vilaça, Fernando C. Schmitt, Adhemar Longatto-Filho, Joana Paredes, Fátima Baltazar,  and Céline Pinheiro
19177-19189
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

GPER agonist G-1 decreases adrenocortical carcinoma (ACC) cell growth in vitro and in vivo

GPER agonist G-1 decreases adrenocortical carcinoma (ACC) cell growth in vitro and in vivo

https://doi.org/10.18632/oncotarget.4241

Adele Chimento, Rosa Sirianni, Ivan Casaburi, Fabiana Zolea, Pietro Rizza, Paola Avena, Rocco Malivindi, Arianna De Luca, Carmela Campana, Emilia Martire, Francesco Domanico, Francesco Fallo, Giulia Carpinelli, Lidia Cerquetti, Donatella Amendola, Antonio Stigliano,  and Vincenzo Pezzi
19190-19203
Abstract  |  PDF  |  HTML  |  Order a Reprint

Classification and clinical behavior of blastic plasmacytoid dendritic cell neoplasms according to their maturation-associated immunophenotypic profile

Classification and clinical behavior of blastic plasmacytoid dendritic cell neoplasms according to their maturation-associated immunophenotypic profile

https://doi.org/10.18632/oncotarget.4146

Lourdes Martín-Martín, Antonio López, Belén Vidriales, María Dolores Caballero, António Silva Rodrigues, Silvia Inês Ferreira, Margarida Lima, Sérgio Almeida, Berta Valverde, Pilar Martínez, Ana Ferrer, Jorge Candeias, Francisco Ruiz-Cabello, Josefa Marco Buadesa, Amparo Sempere, Neus Villamor, Alberto Orfao,  and Julia Almeida
19204-19216
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Elevated preoperative aspartate aminotransferase to lymphocyte ratio index as an independent prognostic factor for patients with hepatocellular carcinoma after hepatic resection

Elevated preoperative aspartate aminotransferase to lymphocyte ratio index as an independent prognostic factor for patients with hepatocellular carcinoma after hepatic resection

https://doi.org/10.18632/oncotarget.4265

Junfei Jin, Pengpeng Zhu, Yan Liao, Jun Li, Weijia Liao,  and Songqing He
19217-19227
Abstract  |  PDF  |  HTML  |  Order a Reprint

The presence of wild type p53 in hematological cancers improves the efficacy of combinational therapy targeting metabolism

The presence of wild type p53 in hematological cancers improves the efficacy of combinational therapy targeting metabolism

https://doi.org/10.18632/oncotarget.4653

Nerea Allende-Vega, Ewelina Krzywinska, Stefania Orecchioni, Nuria Lopez-Royuela, Francesca Reggiani, Giovanna Talarico, Jean-François Rossi, Rodrigue Rossignol, Yosr Hicheri, Guillaume Cartron, Francesco Bertolini,  and Martin Villalba
19228-19245
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Circulating small non coding RNA signature in head and neck squamous cell carcinoma

Circulating small non coding RNA signature in head and neck squamous cell carcinoma

https://doi.org/10.18632/oncotarget.4266

Berta Victoria Martinez, Joseph M. Dhahbi, Yury O. Nunez Lopez, Katarzyna Lamperska, Paweł Golusinski, Lukasz Luczewski, Tomasz Kolenda, Hani Atamna, Stephen R. Spindler, Wojciech Golusinski,  and Michal M. Masternak
19246-19263
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Mucin1 promotes the migration and invasion of hepatocellular carcinoma cells via JNK-mediated phosphorylation of Smad2 at the C-terminal and linker regions

Mucin1 promotes the migration and invasion of hepatocellular carcinoma cells via JNK-mediated phosphorylation of Smad2 at the C-terminal and linker regions

https://doi.org/10.18632/oncotarget.4267

Juan Wang, Guomu Liu, Qiongshu Li, Fang Wang, Fei Xie, Ruiping Zhai, Yingying Guo, Tanxiu Chen, Nannan Zhang, Weihua Ni, Hongyan Yuan,  and Guixiang Tai
19264-19278
Abstract  |  PDF  |  HTML  |  Order a Reprint

Tracking sub-clonal TP53 mutated tumor cells in human metastatic renal cell carcinoma

Tracking sub-clonal TP53 mutated tumor cells in human metastatic renal cell carcinoma

https://doi.org/10.18632/oncotarget.4220

Guilhem Bousquet, Morad El Bouchtaoui, Christophe Leboeuf, Maxime Battistella, Mariana Varna, Irmine Ferreira, Louis-François Plassa, Diaddin Hamdan, Philippe Bertheau, Jean-Paul Feugeas, Diane Damotte,  and Anne Janin
19279-19289
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Infiltrating neutrophils promote renal cell carcinoma progression via VEGFa/HIF2α and estrogen receptor β signals

Infiltrating neutrophils promote renal cell carcinoma progression via VEGFa/HIF2α and estrogen receptor β signals

https://doi.org/10.18632/oncotarget.4478

Wenbin Song, Chiuan-Ren Yeh, Dalin He, Yong Wang, Hongjun Xie, See-Tong Pang, Luke Sien-Shih Chang, Lei Li,  and Shuyuan Yeh
19290-19304
Abstract  |  PDF  |  HTML  |  Order a Reprint

Clinical Research Papers

Impact of VEGF, VEGFR, PDGFR, HIF and ERCC1 gene polymorphisms on thymic malignancies outcome after thymectomy

Impact of VEGF, VEGFR, PDGFR, HIF and ERCC1 gene polymorphisms on thymic malignancies outcome after thymectomy

https://doi.org/10.18632/oncotarget.4191

Rossana Berardi, Alessandro Brunelli, Silvia Pagliaretta, Vittorio Paolucci, Alessandro Conti, Gaia Goteri, Majed Refai, Cecilia Pompili, Giulia Marcantognini, Francesca Morgese, Zelmira Ballatore, Agnese Savini, Mariagrazia De Lisa, Miriam Caramanti, Matteo Santoni, Antonio Zizzi, Francesco Piva, Paola Mazzanti, Azzurra Onofri, Armando Sabbatini, Marina Scarpelli,  and Stefano Cascinu
19305-19315
Abstract  |  PDF  |  HTML  |  Order a Reprint

Predictors of early treatment discontinuation in patients enrolled on Phase I oncology trials

Predictors of early treatment discontinuation in patients enrolled on Phase I oncology trials

https://doi.org/10.18632/oncotarget.2909

David M. Hyman, Anne A. Eaton, Mrinal M. Gounder, Erika G. Pamer, Jasmine Pettiford, Richard D. Carvajal, S. Percy Ivy, Alexia Iasonos,  and David R. Spriggs
19316-19327
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Detection of high mobility group A2 specific mRNA in the plasma of patients affected by epithelial ovarian cancer

Detection of high mobility group A2 specific mRNA in the plasma of patients affected by epithelial ovarian cancer

https://doi.org/10.18632/oncotarget.2896

Francesca Galdiero, Annunciata Romano, Rosa Pasquinelli, Sandro Pignata, Stefano Greggi, Emilia Vuttariello, Anna Maria Bello, Celeste Calise, Cono Scaffa, Carmela Pisano, Nunzia Simona Losito, Alfredo Fusco, Daniela Califano,  and Gennaro Chiappetta
19328-19335
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint


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