Oncotarget

Vol 6, No 15

May 30, 2015

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p38γ and p38δ deletion decreases epithelial cell proliferation. See Zur et al.

Table of Contents

Editorial

Astrocytes: targets in obesity

Astrocytes: targets in obesity

https://doi.org/10.18632/oncotarget.4297

Yunlei Yang
12835-12836
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Reviews

miR-29s: a family of epi-miRNAs with therapeutic implications in hematologic malignancies

miR-29s: a family of epi-miRNAs with therapeutic implications in hematologic malignancies

https://doi.org/10.18632/oncotarget.3805

Nicola Amodio, Marco Rossi, Lavinia Raimondi, Maria Rita Pitari, Cirino Botta, Pierosandro Tagliaferri,  and Pierfrancesco Tassone
12837-12861
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New dimension in therapeutic targeting of BCL-2 family proteins

New dimension in therapeutic targeting of BCL-2 family proteins

https://doi.org/10.18632/oncotarget.3868

Samaher Besbes, Massoud Mirshahi, Marc Pocard,  and Christian Billard
12862-12871
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Deubiquitinases in cancer

Deubiquitinases in cancer

https://doi.org/10.18632/oncotarget.3671

Rongbin Wei, Xiaodong Liu, Weixin Yu, Tianshu Yang, Wenping Cai, Junjun Liu, Xiao Huang, Guo-tong Xu, Shouliang Zhao, Jianhua Yang,  and Shangfeng Liu
12872-12889
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Is the future of personalized therapy in triple-negative breast cancer based on molecular subtype?

Is the future of personalized therapy in triple-negative breast cancer based on molecular subtype?

https://doi.org/10.18632/oncotarget.3849

Fanny Le Du, Bedrich L. Eckhardt, Bora Lim, Jennifer K. Litton, Stacy Moulder, Funda Meric-Bernstam, Ana M. Gonzalez-Angulo,  and Naoto T. Ueno
12890-12908
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Research Perspectives

Energy excess is the main cause of accelerated aging of mammals

Energy excess is the main cause of accelerated aging of mammals

https://doi.org/10.18632/oncotarget.4271

Tomasz Biliński, Tadeusz Paszkiewicz,  and Renata Zadrag-Tecza
12909-12919
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Priority Research Papers

Combined deletion of p38γ and p38δ reduces skin inflammation and protects from carcinogenesis

Combined deletion of p38γ and p38δ reduces skin inflammation and protects from carcinogenesis

https://doi.org/10.18632/oncotarget.4320

Rafal Zur, Laura Garcia-Ibanez, Angel Nunez-Buiza, Noelia Aparicio, Georgios Liappas, Alejandra Escós, Ana Risco, Angustias Page, Cristina Saiz-Ladera, Dayanira Alsina-Beauchamp, José Montans, Jesús M. Paramio,  and Ana Cuenda
12920-12935
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Research Papers: Pathology

Efficacy of the antimicrobial peptide TP4 against Helicobacter pylori infection: in vitro membrane perturbation via micellization and in vivo suppression of host immune responses in a mouse model

Efficacy of the antimicrobial peptide TP4 against Helicobacter pylori infection: in vitro membrane perturbation via micellization and in vivo suppression of host immune responses in a mouse model

https://doi.org/10.18632/oncotarget.4101

Jayaram Lakshmaiah Narayana, Han-Ning Huang, Chang-Jer Wu,  and Jyh-Yih Chen
12936-12954
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Use of tilapia piscidin 3 (TP3) to protect against MRSA infection in mice with skin injuries

Use of tilapia piscidin 3 (TP3) to protect against MRSA infection in mice with skin injuries

https://doi.org/10.18632/oncotarget.4102

Han-Ning Huang, Yi-Lin Chan, Cho-Fat Hui, Jen-Leih Wu, Chang-Jer Wu,  and Jyh-Yih Chen
12955-12969
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Assessment and diagnostic relevance of novel serum biomarkers for early decision of ST-elevation myocardial infarction

Assessment and diagnostic relevance of novel serum biomarkers for early decision of ST-elevation myocardial infarction

https://doi.org/10.18632/oncotarget.4001

Hun-Jun Park, Ji Heon Noh, Jung Woo Eun, Yoon-Seok Koh, Suk Min Seo, Won Sang Park, Jung Young Lee, Kiyuk Chang, Ki Bae Seung, Pum-Joon Kim,  and Suk Woo Nam
12970-12983
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Differential gene expression in human abdominal aortic aneurysm and aortic occlusive disease

Differential gene expression in human abdominal aortic aneurysm and aortic occlusive disease

https://doi.org/10.18632/oncotarget.3848

Erik Biros, Gabor Gäbel, Corey S. Moran, Charlotte Schreurs, Jan H. N. Lindeman, Philip J. Walker, Maria Nataatmadja, Malcolm West, Lesca M. Holdt, Irene Hinterseher, Christian Pilarsky,  and Jonathan Golledge
12984-12996
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Research Papers: Gerotarget (Focus on Aging)

PTPRD silencing by DNA hypermethylation decreases insulin receptor signaling and leads to type 2 diabetes

PTPRD silencing by DNA hypermethylation decreases insulin receptor signaling and leads to type 2 diabetes

https://doi.org/10.18632/oncotarget.4092

Yng-Tay Chen, Wei-De Lin, Wen-Lin Liao, Ying-Ju Lin, Jan-Gowth Chang,  and Fuu-Jen Tsai
12997-13005
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Research Papers

PKM2 promotes glucose metabolism and cell growth in gliomas through a mechanism involving a let-7a/c-Myc/hnRNPA1 feedback loop

PKM2 promotes glucose metabolism and cell growth in gliomas through a mechanism involving a let-7a/c-Myc/hnRNPA1 feedback loop

https://doi.org/10.18632/oncotarget.3514

Wenkang Luan, Yingyi Wang, Xincheng Chen, Yan Shi, Jiajia Wang, Junxia Zhang, Jin Qian, Ri Li, Tao Tao, Wenjin Wei, Qi Hu, Ning Liu,  and Yongping You
13006-13018
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Molecular mechanisms of human IRE1 activation through dimerization and ligand binding

Molecular mechanisms of human IRE1 activation through dimerization and ligand binding

https://doi.org/10.18632/oncotarget.3864

Amar Joshi, Yvette Newbatt, P. Craig McAndrew, Mark Stubbs, Rosemary Burke, Mark W. Richards, Chitra Bhatia, John J. Caldwell, Tatiana McHardy, Ian Collins,  and Richard Bayliss
13019-13035
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PI3K/AKT/mTOR pathway plays a major pathogenetic role in glycogen accumulation and tumor development in renal distal tubules of rats and men

PI3K/AKT/mTOR pathway plays a major pathogenetic role in glycogen accumulation and tumor development in renal distal tubules of rats and men

https://doi.org/10.18632/oncotarget.3675

Silvia Ribback, Antonio Cigliano, Nils Kroeger, Maria G. Pilo, Luigi Terracciano, Martin Burchardt, Peter Bannasch, Diego F. Calvisi,  and Frank Dombrowski
13036-13048
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Wedelolactone disrupts the interaction of EZH2-EED complex and inhibits PRC2-dependent cancer

Wedelolactone disrupts the interaction of EZH2-EED complex and inhibits PRC2-dependent cancer

https://doi.org/10.18632/oncotarget.3790

Huiming Chen, Shijuan Gao, Jiandong Li, Dong Liu, Chunjie Sheng, Chen Yao, Wei Jiang, Jiaoxiang Wu, Shuai Chen,  and Wenlin Huang
13049-13059
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Swiprosin-1 stimulates cancer invasion and metastasis by increasing the Rho family of GTPase signaling

Swiprosin-1 stimulates cancer invasion and metastasis by increasing the Rho family of GTPase signaling

https://doi.org/10.18632/oncotarget.3637

Yun Hyun Huh, Sena Oh, Yu Ra Yeo, In Hee Chae, So Hee Kim, Ji Shin Lee, Sook Jung Yun, Kyu Yeong Choi, Je-Hwang Ryu, Chang-Duk Jun,  and Woo Keun Song
13060-13071
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Wee1 is required to sustain ATR/Chk1 signaling upon replicative stress

Wee1 is required to sustain ATR/Chk1 signaling upon replicative stress

https://doi.org/10.18632/oncotarget.3865

Priyanka Saini, Yizhu Li,  and Matthias Dobbelstein
13072-13087
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Identification of novel genes that regulate androgen receptor signaling and growth of androgen-deprived prostate cancer cells

Identification of novel genes that regulate androgen receptor signaling and growth of androgen-deprived prostate cancer cells

https://doi.org/10.18632/oncotarget.3743

Elina Levina, Hao Ji, Mengqiang Chen, Mirza Baig, David Oliver, Patrice Ohouo, Chang-uk Lim, Garry Schools, Steven Carmack, Ye Ding, Eugenia V. Broude, Igor B. Roninson, Ralph Buttyan,  and Michael Shtutman
13088-13104
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PI3K inhibition synergizes with glucocorticoids but antagonizes with methotrexate in T-cell acute lymphoblastic leukemia

PI3K inhibition synergizes with glucocorticoids but antagonizes with methotrexate in T-cell acute lymphoblastic leukemia

https://doi.org/10.18632/oncotarget.3524

André Bortolini Silveira, Angelo Brunelli Albertoni Laranjeira, Gisele Olinto Libanio Rodrigues, Rodrigues Leal, Bruno António Cardoso, João Taborda Barata, Rosendo Augusto Yunes, Nilson Ivo Tonin Zanchin, Sílvia Regina Brandalise,  and José Andrés Yunes
13105-13118
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Anti-tumor activity of selective inhibitors of XPO1/CRM1-mediated nuclear export in diffuse malignant peritoneal mesothelioma: the role of survivin

Anti-tumor activity of selective inhibitors of XPO1/CRM1-mediated nuclear export in diffuse malignant peritoneal mesothelioma: the role of survivin

https://doi.org/10.18632/oncotarget.3761

Michelandrea De Cesare, Denis Cominetti, Valentina Doldi, Alessia Lopergolo, Marcello Deraco, Paolo Gandellini, Sharon Friedlander, Yosef Landesman, Michael G. Kauffman, Sharon Shacham, Marzia Pennati,  and Nadia Zaffaroni
13119-13132
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Targeting tumors with a killer-reporter adenovirus for curative fluorescence-guided surgery of soft-tissue sarcoma

Targeting tumors with a killer-reporter adenovirus for curative fluorescence-guided surgery of soft-tissue sarcoma

https://doi.org/10.18632/oncotarget.3811

Shuya Yano, Shinji Miwa, Hiroyuki Kishimoto, Fuminari Uehara, Hiroshi Tazawa, Makoto Toneri, Yukihiko Hiroshima, Mako Yamamoto, Yasuo Urata, Shunsuke Kagawa, Michael Bouvet, Toshiyoshi Fujiwara,  and Robert M. Hoffman
13133-13148
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miR-497 and miR-34a retard lung cancer growth by co-inhibiting cyclin E1 (CCNE1)

miR-497 and miR-34a retard lung cancer growth by co-inhibiting cyclin E1 (CCNE1)

https://doi.org/10.18632/oncotarget.3693

Zhiyuan Han, Yanbin Zhang, Qiaoyuan Yang, Binbin Liu, Jianjun Wu, Yajie Zhang, Chengfeng Yang,  and Yiguo Jiang
13149-13163
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MiR-744 functions as a proto-oncogene in nasopharyngeal carcinoma progression and metastasis via transcriptional control of ARHGAP5

MiR-744 functions as a proto-oncogene in nasopharyngeal carcinoma progression and metastasis via transcriptional control of ARHGAP5

https://doi.org/10.18632/oncotarget.3754

Yuan Fang, Xiaoxia Zhu, Jian Wang, Na Li, Dianhe Li, Nazmus Sakib, Zhou Sha,  and Wen Song
13164-13175
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MicroRNA networks regulated by all-trans retinoic acid and Lapatinib control the growth, survival and motility of breast cancer cells

MicroRNA networks regulated by all-trans retinoic acid and Lapatinib control the growth, survival and motility of breast cancer cells

https://doi.org/10.18632/oncotarget.3759

James Neil Fisher, Mineko Terao, Maddalena Fratelli, Mami Kurosaki, Gabriela Paroni, Adriana Zanetti, Maurizio Gianni, Marco Bolis, Monica Lupi, Anna Tsykin, Gregory J. Goodall,  and Enrico Garattini
13176-13200
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MiR-1 downregulation correlates with poor survival in clear cell renal cell carcinoma where it interferes with cell cycle regulation and metastasis

MiR-1 downregulation correlates with poor survival in clear cell renal cell carcinoma where it interferes with cell cycle regulation and metastasis

https://doi.org/10.18632/oncotarget.3915

Haibing Xiao, Jin Zeng, Heng Li, Ke Chen, Gan Yu, Junhui Hu, Kun Tang, Hui Zhou, Qihong Huang, Anping Li, Yi Li, Zhangqun Ye, Ji Wang,  and Hua Xu
13201-13215
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MicroRNA-212 suppresses tumor growth of human hepatocellular carcinoma by targeting FOXA1

MicroRNA-212 suppresses tumor growth of human hepatocellular carcinoma by targeting FOXA1

https://doi.org/10.18632/oncotarget.3916

Changwei Dou, Yufeng Wang, Chao Li, Zhikui Liu, Yuli Jia, Qing Li, Wei Yang, Yingmin Yao, Qingguang Liu,  and Kangsheng Tu
13216-13228
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Massive parallel IGHV gene sequencing reveals a germinal center pathway in origins of human multiple myeloma

Massive parallel IGHV gene sequencing reveals a germinal center pathway in origins of human multiple myeloma

https://doi.org/10.18632/oncotarget.3644

Graeme Cowan, Nicola J. Weston-Bell, Dean Bryant, Anja Seckinger, Dirk Hose, Niklas Zojer,  and Surinder S. Sahota
13229-13240
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CDC20 maintains tumor initiating cells

CDC20 maintains tumor initiating cells

https://doi.org/10.18632/oncotarget.3676

Qi Xie, Qiulian Wu, Stephen C. Mack, Kailin Yang, Leo Kim, Christopher G. Hubert, William A. Flavahan, Chengwei Chu, Shideng Bao,  and Jeremy N. Rich
13241-13254
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Bruton’s tyrosine kinase (Btk) inhibitor ibrutinib suppresses stem-like traits in ovarian cancer

Bruton’s tyrosine kinase (Btk) inhibitor ibrutinib suppresses stem-like traits in ovarian cancer

https://doi.org/10.18632/oncotarget.3658

Muhammad Ary Zucha, Alexander T.H. Wu, Wei-Hwa Lee, Liang-Shun Wang, Wan-Wan Lin, Chiou-Chung Yuan,  and Chi-Tai Yeh
13255-13268
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Absolute quantification of the pretreatment PML-RARA transcript defines the relapse risk in acute promyelocytic leukemia

Absolute quantification of the pretreatment PML-RARA transcript defines the relapse risk in acute promyelocytic leukemia

https://doi.org/10.18632/oncotarget.3773

Francesco Albano, Antonella Zagaria, Luisa Anelli, Nicoletta Coccaro, Giuseppina Tota, Claudia Brunetti, Crescenzio Francesco Minervini, Luciana Impera, Angela Minervini, Angelo Cellamare, Paola Orsini, Cosimo Cumbo, Paola Casieri,  and Giorgina Specchia
13269-13277
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Chronic exposure to cerebrospinal fluid of multiple system atrophy in neuroblastoma and glioblastoma cells induces cytotoxicity via ER stress and autophagy activation

Chronic exposure to cerebrospinal fluid of multiple system atrophy in neuroblastoma and glioblastoma cells induces cytotoxicity via ER stress and autophagy activation

https://doi.org/10.18632/oncotarget.3748

Xuejing Wang, Mingming Ma, Junfang Teng, Jiewen Zhang, Shuang Zhou, Ying Zhang, Erxi Wu,  and Xuebing Ding
13278-13294
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Deregulation of focal adhesion pathway mediated by miR-659-3p is implicated in bone marrow infiltration of stage M neuroblastoma patients

Deregulation of focal adhesion pathway mediated by miR-659-3p is implicated in bone marrow infiltration of stage M neuroblastoma patients

https://doi.org/10.18632/oncotarget.3745

Sara Stigliani, Paola Scaruffi, Corrado Lagazio, Luca Persico, Barbara Carlini, Luigi Varesio, Fabio Morandi, Martina Morini, Anna Rita Gigliotti, Maria Rosaria Esposito, Elisabetta Viscardi, Valerio Cecinati, Massimo Conte,  and Maria Valeria Corrias
13295-13308
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Prognostic value of MET protein overexpression and gene amplification in locoregionally advanced nasopharyngeal carcinoma

Prognostic value of MET protein overexpression and gene amplification in locoregionally advanced nasopharyngeal carcinoma

https://doi.org/10.18632/oncotarget.3751

Yingqin Li, Wenfei Li, Qingmei He, Yafei Xu, Xianyue Ren, Xinran Tang, Xin Wen, Xiaojing Yang, Ying Sun, Jing Zeng, Jingping Yun, Na Liu,  and Jun Ma
13309-13319
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Tyrosine dephosphorylation enhances the therapeutic target activity of epidermal growth factor receptor (EGFR) by disrupting its interaction with estrogen receptor (ER)

Tyrosine dephosphorylation enhances the therapeutic target activity of epidermal growth factor receptor (EGFR) by disrupting its interaction with estrogen receptor (ER)

https://doi.org/10.18632/oncotarget.3645

Shao Ma, Ning Yin, Xiaomei Qi, Sandra L. Pfister, Mei-Jie Zhang, Rong Ma,  and Guan Chen
13320-13333
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Effects of RAL signal transduction in KRAS- and BRAF-mutated cells and prognostic potential of the RAL signature in colorectal cancer

Effects of RAL signal transduction in KRAS- and BRAF-mutated cells and prognostic potential of the RAL signature in colorectal cancer

https://doi.org/10.18632/oncotarget.3871

Balázs Győrffy, Iwona Stelniec-Klotz, Christian Sigler, Katharina Kasack, Torben Redmer, Yu Qian,  and Reinhold Schäfer
13334-13346
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Does beer, wine or liquor consumption correlate with the risk of renal cell carcinoma? A dose-response meta-analysis of prospective cohort studies

Does beer, wine or liquor consumption correlate with the risk of renal cell carcinoma? A dose-response meta-analysis of prospective cohort studies

https://doi.org/10.18632/oncotarget.3749

Xin Xu, Yi Zhu, Xiangyi Zheng,  and Liping Xie
13347-13358
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

HOXB13 and ALX4 induce SLUG expression for the promotion of EMT and cell invasion in ovarian cancer cells

HOXB13 and ALX4 induce SLUG expression for the promotion of EMT and cell invasion in ovarian cancer cells

https://doi.org/10.18632/oncotarget.3673

Hong Yuan, Hiroaki Kajiyama, Satoko Ito, Dan Chen, Kiyosumi Shibata, Michinari Hamaguchi, Fumitaka Kikkawa,  and Takeshi Senga
13359-13370
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Metabolomic profile of glycolysis and the pentose phosphate pathway identifies the central role of glucose-6-phosphate dehydrogenase in clear cell-renal cell carcinoma

Metabolomic profile of glycolysis and the pentose phosphate pathway identifies the central role of glucose-6-phosphate dehydrogenase in clear cell-renal cell carcinoma

https://doi.org/10.18632/oncotarget.3823

Giuseppe Lucarelli, Vanessa Galleggiante, Monica Rutigliano, Francesca Sanguedolce, Simona Cagiano, Pantaleo Bufo, Gaetano Lastilla, Eugenio Maiorano, Domenico Ribatti, Andrea Giglio, Grazia Serino, Antonio Vavallo, Carlo Bettocchi, Francesco Paolo Selvaggi, Michele Battaglia,  and Pasquale Ditonno
13371-13386
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Aberrant plasma levels of circulating miR-16, miR-107, miR-130a and miR-146a are associated with lymph node metastasis and receptor status of breast cancer patients

Aberrant plasma levels of circulating miR-16, miR-107, miR-130a and miR-146a are associated with lymph node metastasis and receptor status of breast cancer patients

https://doi.org/10.18632/oncotarget.3874

Isabel Stückrath, Brigitte Rack, Wolfgang Janni, Bernadette Jäger, Klaus Pantel,  and Heidi Schwarzenbach
13387-13401
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Peritoneal expression of Matrilysin helps identify early post-operative recurrence of colorectal cancer

Peritoneal expression of Matrilysin helps identify early post-operative recurrence of colorectal cancer

https://doi.org/10.18632/oncotarget.2830

Giuseppe S. Sica, Cristina Fiorani, Carmine Stolfi, Giovanni Monteleone, Eleonora Candi, Ivano Amelio, Valeria Catani, Simone Sibio, Andrea Divizia, Giorgia Tema, Edoardo Iaculli,  and Achille L. Gaspari
13402-13415
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Deregulation of PPARβ/δ target genes in tumor-associated macrophages by fatty acid ligands in the ovarian cancer microenvironment

Deregulation of PPARβ/δ target genes in tumor-associated macrophages by fatty acid ligands in the ovarian cancer microenvironment

https://doi.org/10.18632/oncotarget.3826

Tim Schumann, Till Adhikary, Annika Wortmann, Florian Finkernagel, Sonja Lieber, Evelyn Schnitzer, Nathalie Legrand, Yvonne Schober, W. Andreas Nockher, Philipp M. Toth, Wibke E. Diederich, Andrea Nist, Thorsten Stiewe, Uwe Wagner, Silke Reinartz, Sabine Müller-Brüsselbach,  and Rolf Müller
13416-13433
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PTPRG suppresses tumor growth and invasion via inhibition of Akt signaling in nasopharyngeal carcinoma

PTPRG suppresses tumor growth and invasion via inhibition of Akt signaling in nasopharyngeal carcinoma

https://doi.org/10.18632/oncotarget.3876

Arthur Kwok Leung Cheung, Joseph Chok Yan Ip, Adrian Chi Hang Chu, Yue Cheng, Merrin Man Long Leong, Josephine Mun Yee Ko, Wai Ho Shuen, Hong Lok Lung,  and Maria Li Lung
13434-13447
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Expansion of myeloid-derived suppressor cells with arginase activity lasts longer in aged than in young mice after CpG-ODN plus IFA treatment

Expansion of myeloid-derived suppressor cells with arginase activity lasts longer in aged than in young mice after CpG-ODN plus IFA treatment

https://doi.org/10.18632/oncotarget.3626

María F. Harman, Romina P. Ranocchia, Carolina V. Gorlino, María F. Sánchez Vallecillo, Sofía D. Castell, María I. Crespo, Belkys A. Maletto, Gabriel Morón,  and María C. Pistoresi-Palencia
13448-13461
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Unlocking the potential of CD70 as a novel immunotherapeutic target for non-small cell lung cancer

Unlocking the potential of CD70 as a novel immunotherapeutic target for non-small cell lung cancer

https://doi.org/10.18632/oncotarget.3880

Julie Jacobs, Karen Zwaenepoel, Christian Rolfo, Jolien Van den Bossche, Christophe Deben, Karen Silence, Christophe Hermans, Evelien Smits, Paul Van Schil, Filip Lardon, Vanessa Deschoolmeester,  and Patrick Pauwels
13462-13475
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

YM155 potently triggers cell death in breast cancer cells through an autophagy-NF-kB network

YM155 potently triggers cell death in breast cancer cells through an autophagy-NF-kB network

https://doi.org/10.18632/oncotarget.3638

Eloïse Véquaud, Céline Séveno, Delphine Loussouarn, Lucie Engelhart, Mario Campone, Philippe Juin,  and Sophie Barillé-Nion
13476-13486
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Nimotuzumab increases the anti-tumor effect of photodynamic therapy in an oral tumor model

Nimotuzumab increases the anti-tumor effect of photodynamic therapy in an oral tumor model

https://doi.org/10.18632/oncotarget.3622

Ramaswamy Bhuvaneswari, Qin Feng Ng, Patricia S.P. Thong,  and Khee-Chee Soo
13487-13505
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PDL1 expression in inflammatory breast cancer is frequent and predicts for the pathological response to chemotherapy

PDL1 expression in inflammatory breast cancer is frequent and predicts for the pathological response to chemotherapy

https://doi.org/10.18632/oncotarget.3642

François Bertucci, Pascal Finetti, Cécile Colpaert, Emilie Mamessier, Maxime Parizel, Luc Dirix, Patrice Viens, Daniel Birnbaum,  and Steven Van Laere
13506-13519
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Cyr61 as mediator of Src signaling in triple negative breast cancer cells

Cyr61 as mediator of Src signaling in triple negative breast cancer cells

https://doi.org/10.18632/oncotarget.3760

María Pilar Sánchez-Bailón, Annarica Calcabrini, Víctor Mayoral-Varo, Agnese Molinari, Kay-Uwe Wagner, Jesús Pérez Losada, Sergio Ciordia, Juan Pablo Albar,  and Jorge Martín-Pérez
13520-13538
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Highly sensitive and specific novel biomarkers for the diagnosis of transitional bladder carcinoma

Highly sensitive and specific novel biomarkers for the diagnosis of transitional bladder carcinoma

https://doi.org/10.18632/oncotarget.3841

Prashant Kumar, Sayantani Nandi, Tuan Zea Tan, Siok Ghee Ler, Kee Seng Chia, Wei-Yen Lim, Zentia Bütow, Dimitrios Vordos, Alexandre De laTaille, Muthafar Al-Haddawi, Manfred Raida, Burkhard Beyer, Estelle Ricci, Marc Colombel, Tsung Wen Chong, Edmund Chiong, Ross Soo, Mi Kyoung Park, Hong Koo Ha, Jayantha Gunaratne,  and Jean Paul Thiery
13539-13549
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Immunoglobulin-like transcript 4 promotes tumor progression and metastasis and up-regulates VEGF-C expression via ERK signaling pathway in non-small cell lung cancer

Immunoglobulin-like transcript 4 promotes tumor progression and metastasis and up-regulates VEGF-C expression via ERK signaling pathway in non-small cell lung cancer

https://doi.org/10.18632/oncotarget.3624

Pei Zhang, Xiaosun Guo, Juan Li, Shuwen Yu, Linlin Wang, Guosheng Jiang, Dong Yang, Zhaolong Wei, Nan Zhang, Jie Liu,  and Yuping Sun
13550-13563
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A novel Golgi protein (GOLPH2)-regulated oncolytic adenovirus exhibits potent antitumor efficacy in hepatocellular carcinoma

A novel Golgi protein (GOLPH2)-regulated oncolytic adenovirus exhibits potent antitumor efficacy in hepatocellular carcinoma

https://doi.org/10.18632/oncotarget.3769

Yigang Wang, Tao Liu, Panpan Huang, Hongfang Zhao, Rong Zhang, Buyun Ma, Kan Chen, Fang Huang, Xiumei Zhou, Caixia Cui,  and Xinyuan Liu
13564-13578
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Printed peptide arrays identify prognostic TNC serumantibodies in glioblastoma patients

Printed peptide arrays identify prognostic TNC serumantibodies in glioblastoma patients

https://doi.org/10.18632/oncotarget.3791

Andreas Mock, Rolf Warta, Christoph Geisenberger, Ralf Bischoff, Alexander Schulte, Katrin Lamszus, Volker Stadler, Thomas Felgenhauer, Christian Schichor, Christoph Schwartz, Jakob Matschke, Christine Jungk, Rezvan Ahmadi, Felix Sahm, David Capper, Rainer Glass, Jörg-Christian Tonn, Manfred Westphal, Andreas von Deimling, Andreas Unterberg, Justo Lorenzo Bermejo,  and Christel Herold-Mende
13579-13590
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Leupaxin stimulates adhesion and migration of prostate cancer cells through modulation of the phosphorylation status of the actin-binding protein caldesmon

Leupaxin stimulates adhesion and migration of prostate cancer cells through modulation of the phosphorylation status of the actin-binding protein caldesmon

https://doi.org/10.18632/oncotarget.3792

Sascha Dierks, Sandra von Hardenberg, Thomas Schmidt, Felix Bremmer, Peter Burfeind,  and Silke Kaulfuß
13591-13606
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Endogenous molecular network reveals two mechanisms of heterogeneity within gastric cancer

Endogenous molecular network reveals two mechanisms of heterogeneity within gastric cancer

https://doi.org/10.18632/oncotarget.3633

Site Li, Xiaomei Zhu, Bingya Liu, Gaowei Wang,  and Ping Ao
13607-13627
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Enhanced tumorigenicity by mitochondrial DNA mild mutations

Enhanced tumorigenicity by mitochondrial DNA mild mutations

https://doi.org/10.18632/oncotarget.3698

Alberto Cruz-Bermúdez, Carmen G. Vallejo, Ramiro J. Vicente-Blanco, María Esther Gallardo, Miguel Ángel Fernández-Moreno, Miguel Quintanilla,  and Rafael Garesse
13628-13643
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SMYD3 contributes to a more aggressive phenotype of prostate cancer and targets Cyclin D2 through H4K20me3

SMYD3 contributes to a more aggressive phenotype of prostate cancer and targets Cyclin D2 through H4K20me3

https://doi.org/10.18632/oncotarget.3767

Filipa Quintela Vieira, Pedro Costa-Pinheiro, Diogo Almeida-Rios, Inês Graça, Sara Monteiro-Reis, Susana Simões-Sousa, Isa Carneiro, Elsa Joana Sousa, Maria Inês Godinho, Fátima Baltazar, Rui Henrique,  and Carmen Jerónimo
13644-13657
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

MiR-200b/200c/429 subfamily negatively regulates Rho/ROCK signaling pathway to suppress hepatocellular carcinoma metastasis

MiR-200b/200c/429 subfamily negatively regulates Rho/ROCK signaling pathway to suppress hepatocellular carcinoma metastasis

https://doi.org/10.18632/oncotarget.3700

Chun-Ming Wong, Lai Wei, Sandy Leung-Kuen Au, Dorothy Ngo-Yin Fan, Yuan Zhou, Felice Ho-Ching Tsang, Cheuk-Ting Law, Joyce Man-Fong Lee, Xianghuo He, Jue Shi, Carmen Chak-Lui Wong,  and Irene Oi-Lin Ng
13658-13670
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Gene expression in “young adult type” breast cancer: a retrospective analysis

Gene expression in “young adult type” breast cancer: a retrospective analysis

https://doi.org/10.18632/oncotarget.4051

Rebecca H. Johnson, Pingzhao Hu, Cheng Fan,  and Carey K. Anders
13688-13702
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By reducing hexokinase 2, resveratrol induces apoptosis in HCC cells addicted to aerobic glycolysis and inhibits tumor growth in mice

By reducing hexokinase 2, resveratrol induces apoptosis in HCC cells addicted to aerobic glycolysis and inhibits tumor growth in mice

https://doi.org/10.18632/oncotarget.3800

Weiqi Dai, Fan Wang, Jie Lu, Yujing Xia, Lei He, Kan Chen, Jingjing Li, Sainan Li, Tong Liu, Yuanyuan Zheng, Jianrong Wang, Wenxia Lu, Yuqing Zhou, Qin Yin, Huerxidan Abudumijiti, Rongxia Chen, Rong Zhang, Li Zhou, Zheng Zhou, Rong Zhu, Jing Yang, Chengfen Wang, Huawei Zhang, Yingqun Zhou, Ling Xu,  and Chuanyong Guo
13703-13717
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YBX1/YB-1 induces partial EMT and tumourigenicity through secretion of angiogenic factors into the extracellular microenvironment

YBX1/YB-1 induces partial EMT and tumourigenicity through secretion of angiogenic factors into the extracellular microenvironment

https://doi.org/10.18632/oncotarget.3764

Shashi K. Gopal, David W. Greening, Rommel A. Mathias, Hong Ji, Alin Rai, Maoshan Chen, Hong‐Jian Zhu,  and Richard J. Simpson
13718-13730
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Development and characterisation of a 3D multi-cellular in vitro model of normal human breast: a tool for cancer initiation studies

Development and characterisation of a 3D multi-cellular in vitro model of normal human breast: a tool for cancer initiation studies

https://doi.org/10.18632/oncotarget.3803

Claire E. Nash, Georgia Mavria, Euan W. Baxter, Deborah L. Holliday, Darren C. Tomlinson, Darren Treanor, Vera Novitskaya, Fedor Berditchevski, Andrew M. Hanby,  and Valerie Speirs
13731-13741
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Targeted sequencing with enrichment PCR: a novel diagnostic method for the detection of EGFR mutations

Targeted sequencing with enrichment PCR: a novel diagnostic method for the detection of EGFR mutations

https://doi.org/10.18632/oncotarget.3807

Suki Kang, Baek Gil Kim, Hyun Ho Han, Joo Hyun Lee, Ji Eun Kim, Hyo Sup Shim,  and Nam Hoon Cho
13742-13749
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Impact of aging on calcium influx and potassium channel characteristics of T lymphocytes

Impact of aging on calcium influx and potassium channel characteristics of T lymphocytes

https://doi.org/10.18632/oncotarget.3808

Szonja Kollár, László Berta, Zsófia Eszter Vásárhelyi, Attila Balog, Barna Vásárhelyi, János Rigó Jr,  and Gergely Toldi
13750-13756
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Loss of the deubiquitylase BAP1 alters class I histone deacetylase expression and sensitivity of mesothelioma cells to HDAC inhibitors

Loss of the deubiquitylase BAP1 alters class I histone deacetylase expression and sensitivity of mesothelioma cells to HDAC inhibitors

https://doi.org/10.18632/oncotarget.3765

Joseph J. Sacco, Jenna Kenyani, Zohra Butt, Rachel Carter, Hui Yi Chew, Liam P. Cheeseman, Sarah Darling, Michael Denny, Sylvie Urbé, Michael J. Clague,  and Judy M. Coulson
13757-13771
Abstract  |  PDF  |  HTML  |  Order a Reprint

Involvement of multiple myeloma cell-derived exosomes in osteoclast differentiation

Involvement of multiple myeloma cell-derived exosomes in osteoclast differentiation

https://doi.org/10.18632/oncotarget.3830

Lavinia Raimondi, Angela De Luca, Nicola Amodio, Mauro Manno, Samuele Raccosta, Simona Taverna, Daniele Bellavia, Flores Naselli, Simona Fontana, Odessa Schillaci, Roberto Giardino, Milena Fini, Pierfrancesco Tassone, Alessandra Santoro, Giacomo De Leo, Gianluca Giavaresi,  and Riccardo Alessandro
13772-13789
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

A long pentraxin-3-derived pentapeptide for the therapy of FGF8b-driven steroid hormone-regulated cancers

A long pentraxin-3-derived pentapeptide for the therapy of FGF8b-driven steroid hormone-regulated cancers

https://doi.org/10.18632/oncotarget.3831

Arianna Giacomini, Sara Matarazzo, Katiuscia Pagano, Laura Ragona, Sara Rezzola, Michela Corsini, Emanuela Di Salle, Marco Presta,  and Roberto Ronca
13790-13802
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Neutralizing S1P inhibits intratumoral hypoxia, induces vascular remodelling and sensitizes to chemotherapy in prostate cancer

Neutralizing S1P inhibits intratumoral hypoxia, induces vascular remodelling and sensitizes to chemotherapy in prostate cancer

https://doi.org/10.18632/oncotarget.3144

Isabelle Ader, Cécile Gstalder, Pierre Bouquerel, Muriel Golzio, Guillaume Andrieu, Santiago Zalvidea, Sylvain Richard, Roger A. Sabbadini, Bernard Malavaud,  and Olivier Cuvillier
13803-13821
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

An angiopoietin-like protein 2 autocrine signaling promotes EMT during pancreatic ductal carcinogenesis

An angiopoietin-like protein 2 autocrine signaling promotes EMT during pancreatic ductal carcinogenesis

https://doi.org/10.18632/oncotarget.2635

Carmine Carbone, Geny Piro, Matteo Fassan, Anna Tamburrino, Maria Mihaela Mina, Marco Zanotto, Paul J. Chiao, Claudio Bassi, Aldo Scarpa, Giampaolo Tortora,  and Davide Melisi
13822-13834
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Characterization of tumor infiltrating natural killer cell subset

Characterization of tumor infiltrating natural killer cell subset

https://doi.org/10.18632/oncotarget.3453

Inbar Levi, Hagai Amsalem, Aviram Nissan, Merav Darash-Yahana, Tamar Peretz, Ofer Mandelboim,  and Jacob Rachmilewitz
13835-13843
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