Table of Contents
Editorial
| Reaching Un-Drugable Intracellular Targets with the Long Arm of Antibodies |
| David A. Scheinberg, Tao Dao, and Cheng Liu |
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| Anti-cancer drug phenylbutyrate increases activity of pyruvate dehydrogenase complex. |
| Rosa Ferriero, and Nicola Brunetti-Pierri |
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| LDH-A Acetylation: implication in Pancreatic Cancer Initiation and Diagnosis |
| Di Zhao, Yue Xiong, Qun-Ying Lei, and Kun-Liang Guan |
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| Necdin, a p53 target gene, in normal and cancer stem cells |
| Takashi Asai, Yan Liu, and Stephen D Nimer |
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| STAT5b in the pathogenesis of LGL leukemia – a novel therapeutic target? |
| Hanna L. M. Rajala, and Satu Mustjoki |
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| Mouse model resembling human lung cancer |
| Zuoxiang Xiao, Qun Jiang, Jami Willette-Brown, and Yinling Hu |
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| Perturbation of nucleotide metabolism - the driving force of oncogene-induced senescence |
| Zbigniew Darzynkiewicz |
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| Single circulating tumor cell sequencing for tumor genome monitoring |
| Martina Auer, Ellen Heitzer, Peter Ulz, Jochen B. Geigl, and Michael R Speicher |
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| Asymmetric division: a marker for cancer stem cells in early stage tumors? |
| Pengcheng Bu, Kai-Yuan Chen, Steven M Lipkin, and Xiling Shen |
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Research Papers
| MicroRNA-137 is downregulated in glioblastoma and inhibits the stemness of glioma stem cells by targeting RTVP-1 |
| Ariel Bier, Niss Giladi, Noam Kronfeld, Hae Kyung Lee, Simona Cazacu, Susan Finniss, Cunli Xiang, Laila Poisson, Ana C deCarvalho, Shimon Slavin, Elad Jacoby, Michal Yalon, Amos Toren, Tom Mikkelsen, and Chaya Brodie |
| Abstract PDF Full Text |
| Cell death sensitization of leukemia cells by opioid receptor activation |
| Claudia Friesen, Mareike Roscher, Inis Hormann, Iduna Fichtner, Andreas Alt, Ralf Hilger, Klaus-Michael Debatin, and Erich Miltner |
| Abstract PDF Full Text |
| Targeting HSF1 sensitizes cancer cells to HSP90 inhibition |
| Yaoyu Chen, Jinyun Chen, Alice Loo, Savina Jaeger, Linda Bagdasarian, Jianjun Yu, Franklin Chung, Joshua Korn, David Ruddy, Ribo Guo, Margaret Mclaughlin, Fei Feng, Ping Zhu, Frank Stegmeier, Raymond Pagliarini, Dale Porter, and Wenlai Zhou |
| Abstract PDF Full Text Supplementary Files |
| Constitutively-active androgen receptor variants function independently of the HSP90 chaperone but do not confer resistance to HSP90 inhibitors |
| Joanna L Gillis, Luke A Selth, Margaret M Centenera, Scott L Townley, Shihua Sun, Stephen R Plymate, Wayne D Tilley, and Lisa M Butler |
| Abstract PDF Full Text Supplementary Files |
| P53 Mutations in Advanced Cancers: Clinical Characteristics, Outcomes, and Correlation between Progression-Free Survival and Bevacizumab-Containing Therapy |
| Rabih Said, David S. Hong, Carla L. Warneke, J. Jack Lee, Jennifer J. Wheler, Filip Janku, Aung Naing, Gerald S. Falchook, Siqing Fu, Sarina Piha-Paul, Apostolia M. Tsimberidou, and Razelle Kurzrock |
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| Genome-wide comparison of the transcriptomes of highly enriched normal and chronic myeloid leukemia stem and progenitor cell populations |
| Jonathan M. Gerber, Jessica L. Gucwa, David Esopi, Meltem Gurel, Michael C. Haffner, Milada Vala, William G. Nelson, Richard J. Jones, and Srinivasan Yegnasubramanian |
| Abstract PDF Full Text Supplementary Files |
| CK2-NCoR signaling cascade promotes prostate tumorigenesis |
| Jung-Yoon Yoo, Beom Jin Lim, Hyo-Kyoung Choi, Soon Won Hong, Ho Sung Jang, Changsoo Kim, Kyung-Hee Chun, Kyung-Chul Choi, and HoGeun Yoon |
| Abstract PDF Full Text Supplementary Files |
| FAM83B-mediated activation of PI3K/AKT and MAPK signaling cooperates to promote epithelial cell transformation and resistance to targeted therapies. |
| Rocky Cipriano, Kristy L.S. Miskimen, Benjamin L. Bryson, Chase R. Foy, Courtney A. Bartel, and Mark W Jackson |
| Abstract PDF Full Text Supplementary Files |
| Pharmacological targeting of the PI3K/mTOR pathway alters the release of angioregulatory mediators both from primary human acute myeloid leukemia cells and their neighboring stromal cells |
| Håkon Reikvam, Ina Nepstad, Kimberley Joanne Hatfield, and Øystein Bruserud |
| Abstract PDF Full Text |
| Musashi1 as a potential therapeutic target and diagnostic marker for lung cancer |
| Robert I Glazer, Xiao-Yang Wang, Huina Yu, R. Ilona Linnpoila, Laodong Li, Dangyu Li, Biwen Bo, Hideyuki Okano, and Luis O.F. Penalva |
| Abstract PDF Full Text Supplementary Files |
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