Volume 2: Issue 3


Issue 3

About the Cover

The cover for the issue of Oncoscience features Figure 3 (“Characterization of a murine model of metastatic human nonsmall cell lung cancer and effect of CXCR4 inhibition on the growth of metastases”) from Singla et al.


Focally amplified lnc RNA genes in cancer


Lu  Yang, Xiaowen  Hu, Xia  Zhao, Lin  Zhang

p 205-206



HER2 and uPAR cooperativity contribute to metastatic phenotype of HER2-positive breast cancer


Vineesh Indira Chandran, Serenella  Eppenberger-Castori, Thejaswini  Venkatesh, Kara Lea Vine, Marie  Ranson

p 207-224

Abstract |  PDF |  Full Text

Research Perspectives

Dynamic scenario of metabolic pathway adaptation in tumors and therapeutic approach


Silvia  Peppicelli, Francesca  Bianchini, Lido  Calorini

p 225-232

PDF |  Full Text

p53 and Ca2+ signaling from the endoplasmic reticulum: partners in anti-cancer therapies


Mart  Bittremieux, Geert  Bultynck

p 233-238

PDF |  Full Text

Size does not matter: commensal microorganisms forge tumor-promoting inflammation and anti-tumor immunity


Melanie R. Rutkowski, Jose R. Conejo-Garcia

p 239-246

PDF |  Full Text

Inflammatory macrophages in pancreatic acinar cell metaplasia and initiation of pancreatic cancer


Geou-Yarh  Liou, Peter  Storz

p 247-251

PDF |  Full Text

Research Papers

Prognostic microRNAs in high-grade glioma reveal a link to oligodendrocyte precursor differentiation


Josie  Hayes, Helene  Thygesen, Alastair  Droop, Thomas A. Hughes, David  Westhead, Sean E. Lawler, Heiko  Wurdak, Susan  Short

p 252-262

Abstract |  PDF |  Full Text |  Supplementary Materials

Characterization of a murine model of metastatic human non-small cell lung cancer and effect of CXCR4 inhibition on the growth of metastases


Arvind K. Singla, Charlene M. Downey, Gwyn D. Bebb, Frank R. Jirik

p 263-271

Abstract |  PDF |  Full Text |  Supplementary Materials

Synergistic enhancement of 5-fluorouracil cytotoxicity by deoxyuridine analogs in cancer cells


Yoshihiro  Matsumoto, Victoria  Rodriguez, Tracy A. Whitford, Neil  Beeharry, Hiroshi  Ide, Alan E. Tomkinson

p 272-284

Abstract |  PDF |  Full Text |  Supplementary Materials

N of 1 case reports of exceptional responders accrued from pancreatic cancer patients enrolled in first-in-man studies from 2002 through 2012


Ignacio  Garrido-Laguna, Danielle  Tometich, Nan  Hu, Jian  Ying, Katherine  Geiersbach, Jonathan  Whisenant, Kai  Wang, Jeffrey S. Ross, Sunil  Sharma

p 285-293

Abstract |  PDF |  Full Text

P18/Stathmin1 is regulated by miR-31 in ovarian cancer in response to taxane


Mohamed Kamel Hassan, Hidemichi  Watari, Takashi  Mitamura, Zainab  Mohamed, Sherif F. EL-khamisy, Yusuke  Ohba, Noriaki  Sakuragi

p 294-308

Abstract |  PDF |  Full Text |  Supplementary Materials |  Supplementary Video 1 |  Supplementary Video 2

Bone morphogenetic protein 4 (BMP-4) and epidermal growth factor (EGF) inhibit metalloproteinase-9 (MMP-9) expression in cancer cells.


Nathalie Bibens Laulan, Yves  St-Pierre

p 309-316

Abstract |  PDF |  Full Text |  Supplementary Materials