Genes & Cancer

Volume 7: Issue 3-4, March 2016

pp60-147

Issue 3-4, March 2016

About the Cover

The cover for Genes & Cancer features figure 5A (“Coevolution of neoplastic epithelial cells and multilineage stroma via polyploid giant cells during immortalization and transformation of mullerian epithelial cells”) from Zhang et al.

Research Papers

Coevolution of neoplastic epithelial cells and multilineage stroma via polyploid giant cells during immortalization and transformation of mullerian epithelial cells

Shiwu  Zhang , Imelda  Mercado-Uribe , Anil  Sood , Robert C. Bast , and Jinsong  Liu

Abstract |  PDF |  Full Text |  Supplementary Materials   p60 -72

The PI3K inhibitor taselisib overcomes letrozole resistance in a breast cancer model expressing aromatase

Klaus P. Hoeflich , Jane  Guan , Kyle A. Edgar , Carol  O’Brien , Heidi  Savage , Timothy R. Wilson , Richard M. Neve , Lori S. Friedman , and Jeffrey J. Wallin

Abstract |  PDF |  Full Text |  Supplementary Materials   p73 -85

Decreased expression of let-7c is associated with non-response of muscle-invasive bladder cancer patients to neoadjuvant chemotherapy

Ruth L.  Vinall , Clifford G.  Tepper , Alexandra A.Z. Ripoll , Regina F. Gandour- Edwards , Blythe P. Durbin-Johnson , Stanley A. Yap , Paramita M. Ghosh , and Ralph W.  deVere White

Abstract |  PDF |  Full Text |  Supplementary Materials   p86 -97

The adenoviral E1A N-terminal domain represses MYC transcription in human cancer cells by targeting both p300 and TRRAP and inhibiting MYC promoter acetylation of H3K18 and H4K16

Ling-Jun  Zhao , Paul M. Loewenstein , and Maurice  Green

Abstract |  PDF |  Full Text |  Supplementary Materials   p98 -109

MUC16 contributes to the metastasis of pancreatic ductal adenocarcinoma through focal adhesion mediated signaling mechanism

Sakthivel  Muniyan , Dhanya  Haridas , Seema  Chugh , Satyanarayana  Rachagani , Imayavaramban  Lakshmanan , Suprit  Gupta , Parthasarathy  Seshacharyulu , Lynette M. Smith , Moorthy P. Ponnusamy , and Surinder K. Batra

Abstract |  PDF |  Full Text |  Supplementary Materials   p110 -124

FGF19 functions as autocrine growth factor for hepatoblastoma

David J. Elzi , Meihua  Song , Barron  Blackman , Susan T. Weintraub , Dolores  López-Terrada , Yidong  Chen , Gail E. Tomlinson , and Yuzuru  Shiio

Abstract |  PDF |  Full Text |  Supplementary Materials   p125 -135

Epigenetically silenced GNG4 inhibits SDF1α/CXCR4 signaling in mesenchymal glioblastoma

Jagriti  Pal , Vikas  Patil , Baisakhi  Mondal , Sudhanshu  Shukla , Alangar S. Hegde , Arimappamagan  Arivazhagan , Vani  Santosh , and Kumaravel  Somasundaram

Abstract |  PDF |  Full Text |  Supplementary Materials |  Supplementary Tables   p136 -147