Genes & Cancer

Volume 7: Issue 3-4, March 2016

pp60-147

Issue 3-4, March 2016

About the Cover

The cover for Genes & Cancer features figure 5A (“Coevolution of neoplastic epithelial cells and multilineage stroma via polyploid giant cells during immortalization and transformation of mullerian epithelial cells”) from Zhang et al.

Research Papers

Coevolution of neoplastic epithelial cells and multilineage stroma via polyploid giant cells during immortalization and transformation of mullerian epithelial cells

https://doi.org/10.18632/genesandcancer.102

Shiwu  Zhang , Imelda  Mercado-Uribe , Anil  Sood , Robert C. Bast , and Jinsong  Liu

p 60-72

Abstract |  PDF |  Full Text |  Supplementary Materials

The PI3K inhibitor taselisib overcomes letrozole resistance in a breast cancer model expressing aromatase

https://doi.org/10.18632/genesandcancer.100

Klaus P. Hoeflich , Jane  Guan , Kyle A. Edgar , Carol  O’Brien , Heidi  Savage , Timothy R. Wilson , Richard M. Neve , Lori S. Friedman , and Jeffrey J. Wallin

p 73-85

Abstract |  PDF |  Full Text |  Supplementary Materials

Decreased expression of let-7c is associated with non-response of muscle-invasive bladder cancer patients to neoadjuvant chemotherapy

https://doi.org/10.18632/genesandcancer.103

Ruth L.  Vinall , Clifford G.  Tepper , Alexandra A.Z. Ripoll , Regina F. Gandour- Edwards , Blythe P. Durbin-Johnson , Stanley A. Yap , Paramita M. Ghosh , and Ralph W.  deVere White

p 86-97

Abstract |  PDF |  Full Text |  Supplementary Materials

The adenoviral E1A N-terminal domain represses MYC transcription in human cancer cells by targeting both p300 and TRRAP and inhibiting MYC promoter acetylation of H3K18 and H4K16

https://doi.org/10.18632/genesandcancer.99

Ling-Jun  Zhao , Paul M. Loewenstein , and Maurice  Green

p 98-109

Abstract |  PDF |  Full Text |  Supplementary Materials

MUC16 contributes to the metastasis of pancreatic ductal adenocarcinoma through focal adhesion mediated signaling mechanism

https://doi.org/10.18632/genesandcancer.104

Sakthivel  Muniyan , Dhanya  Haridas , Seema  Chugh , Satyanarayana  Rachagani , Imayavaramban  Lakshmanan , Suprit  Gupta , Parthasarathy  Seshacharyulu , Lynette M. Smith , Moorthy P. Ponnusamy , and Surinder K. Batra

p 110-124

Abstract |  PDF |  Full Text |  Supplementary Materials

FGF19 functions as autocrine growth factor for hepatoblastoma

https://doi.org/10.18632/genesandcancer.101

David J. Elzi , Meihua  Song , Barron  Blackman , Susan T. Weintraub , Dolores  López-Terrada , Yidong  Chen , Gail E. Tomlinson , and Yuzuru  Shiio

p 125-135

Abstract |  PDF |  Full Text |  Supplementary Materials

Epigenetically silenced GNG4 inhibits SDF1α/CXCR4 signaling in mesenchymal glioblastoma

https://doi.org/10.18632/genesandcancer.105

Jagriti  Pal , Vikas  Patil , Baisakhi  Mondal , Sudhanshu  Shukla , Alangar S. Hegde , Arimappamagan  Arivazhagan , Vani  Santosh , and Kumaravel  Somasundaram

p 136-147

Abstract |  PDF |  Full Text |  Supplementary Materials |  Supplementary Tables