Genes & Cancer

Volume 6: Issue 5-6, May 2015


Issue 5-6, May 2015

About the Cover

The cover for Genes & Cancer features figure 1 (“Screening of suppressors of bax-induced cell death identifies glycerophosphate oxidase-1 as a mediator of debcl-induced apoptosis in Drosophila”) from Colin et al.


Wee1 and Chk1 – crosstalk between key players in replicative stress

Priyanka  Saini , Yizhu  Li , and Matthias  Dobbelstein

PDF   p182 -183


Histone acetyltransferases and histone deacetylases in B- and T-cell development, physiology and malignancy

Leila  Haery , Ryan C. Thompson , and Thomas D. Gilmore

Abstract |  PDF |  Full Text   p184 -213

Research Perspective

Chronic inflammation: is it the driver or is it paving the road for malignant transformation?

Kambiz  Afrasiabi , Yi-Hong  Zhou , and Angela  Fleischman

Abstract |  PDF |  Full Text   p214 -219

Research Papers

CArG-driven GADD45α activated by resveratrol inhibits lung cancer cells

Qiwen  Shi , Werner  Geldenhuys , Vijaykumar  Sutariya , Anupam  Bishayee , Isha  Patel , and Deepak  Bhatia

Abstract |  PDF |  Full Text   p220 -230

RASSF10 suppresses hepatocellular carcinoma growth by activating P53 signaling and methylation of RASSF10 is a docetaxel resistant marker

Yongshuai  Jin , Baoping  Cao , Meiying  Zhang , Qimin  Zhan , James G. Herman , Miao  Yu , and Mingzhou  Guo

Abstract |  PDF |  Full Text   p231 -240

Screening of suppressors of bax-induced cell death identifies glycerophosphate oxidase-1 as a mediator of debcl-induced apoptosis in Drosophila

Jessie  Colin , Julie  Garibal , Amandine  Clavier , Sébastien  Szuplewski , Yanick  Risler , Cécile  Milet , Sébastien  Gaumer , Isabelle  Guénal , and Bernard  Mignotte

Abstract |  PDF |  Full Text   p241 -253

PSCA s2294008 C>T and rs2976392 G>A polymorphisms contribute to cancer susceptibility: evidence from published studies

Yong  Gu , Qiang-Sheng  Dai , Rui-Xi  Hua , Bing  Zhang , Jin-Hong  Zhu , Jian-Wen  Huang , Bin-Hui  Xie , Shi-Qiu  Xiong , Guo-Sheng  Tan , and He-Ping  Li

Abstract |  PDF |  Full Text   p254 -264

3,3’-Diindolylmethane (DIM) and its ring-substituted halogenated analogs (ring-DIMs) induce differential mechanisms of survival and death in androgen-dependent and –independent prostate cancer cells

Alexander A. Goldberg , Hossam  Draz , Diana  Montes-Grajales , Jesus  Olivero-Verbél , Stephen H. Safe , and J. Thomas Sanderson

Abstract |  PDF |  Full Text |  Supplementary Materials   p265 -280

Circulating microRNAs - a new horizon in molecular diagnosis of breast cancer

Hoda A. Hagrass , Samar  Sharaf , Heba F. Pasha , Enas A. Tantawy , Randa H. Mohamed , and Rasha  Kassem

Abstract |  PDF |  Full Text   p281 -287