Genes & Cancer

Volume 6: Issue 3-4, March 2015

pp82-181

Issue 3-4, March 2015

About the Cover

The cover for Genes & Cancer features figure S6 (“EWS/FLI utilizes NKX2-2 to repress mesenchymal features of Ewing sarcoma”) from Fadul et al.

Editorials

Biguanides and targeted anti-cancer treatments

https://doi.org/10.18632/genesandcancer.59

Elyse K. Hanly , Zbigniew  Darzynkiewicz , and Raj K. Tiwari

p 82-83

PDF

Reviews

Trop2 and its overexpression in cancers: regulation and clinical/ therapeutic implications

https://doi.org/10.18632/genesandcancer.40

Anna  Shvartsur , and Benjamin  Bonavida

p 84-105

Abstract |  PDF |  Full Text

Research Papers

Requirement for BUB1B/BUBR1 in tumor progression of lung adenocarcinoma

https://doi.org/10.18632/genesandcancer.53

Honglin  Chen , James  Lee , Noelyn  Kljavin , Benjamin  Haley , Anneleen  Daemen , Leisa  Johnson , and Yuxin  Liang

p 106-118

Abstract |  PDF |  Full Text |  Supplementary Materials

Drug sensitivity profiling and molecular characteristics of cells from pleural effusions of patients with lung adenocarcinoma

https://doi.org/10.18632/genesandcancer.56

Rita  Ötvös , Adam  Szulkin , Carl-Olof  Hiilerdal , Aytekin  Celep , Eviane  Yousef-Fadhel , Henriette  Skribek , Anders  Hjerpe , Laszlo  Szekely , and Katalin  Dobra

p 119-128

Abstract |  PDF |  Full Text |  Supplementary Materials

EWS/FLI utilizes NKX2-2 to repress mesenchymal features of Ewing sarcoma

https://doi.org/10.18632/genesandcancer.57

John  Fadul , Russell  Bell , Laura M. Hoffman , Mary C. Beckerle , Michael E. Engel , and Stephen L. Lessnick

p 129-143

Abstract |  PDF |  Full Text |  Supplementary Materials

Triptolide and its prodrug minnelide suppress Hsp70 and inhibit in vivo growth in a xenograft model of mesothelioma

https://doi.org/10.18632/genesandcancer.55

Blake A. Jacobson , Esther Z. Chen , Shaogeng  Tang , Holly Sedgwick Belgum , Joel A. McCauley , Kristen A. Evenson , Ryan G. Etchison , Joe  Jay-Dixon , Manish R. Patel , Ahmad  Raza , Ashok K. Saluja , Jonathan  D’Cunha , and Robert A. Kratzke

p 144-152

Abstract |  PDF |  Full Text

Granulin, a novel STAT3-interacting protein, enhances STAT3 transcriptional function and correlates with poorer prognosis in breast cancer

https://doi.org/10.18632/genesandcancer.58

Jennifer E. Yeh , Simion  Kreimer , Sarah R. Walker , Megan M. Emori , Hannah  Krystal , Andrea  Richardson , Alexer R. Ivanov , and David A. Frank

p 153-168

Abstract |  PDF |  Full Text |  Supplementary Materials

Suberoylanilide hydroxamic acid (SAHA) reverses chemoresistance in head and neck cancer cells by targeting cancer stem cells via the downregulation of nanog

https://doi.org/10.18632/genesandcancer.54

Bhavna  Kumar , Arti  Yadav , James C. Lang , Theodoros N. Teknos , and Pawan  Kumar

p 169-181

Abstract |  PDF |  Full Text |  Supplementary Materials