Genes & Cancer

Volume 5: Issue 11-12, November 2014

pp375-479

Issue 11-12, November 2014

About the Cover

The cover for Genes & Cancer features figure 7 (“RGS16, a novel p53 and pRb cross-talk candidate inhibits migration and invasion of pancreatic cancer cells”) from Carper et al.

Meeting Reports

Origins of cancer symposium report: beyond the tumor cell

Andrew M. Howard , Eric A. Nollet , and Nikki M. Thellman

Abstract |  PDF |  Full Text   p375 -377

Research Papers

STAT activation status differentiates leukemogenic from non-leukemogenic stem cells in AML and is suppressed by arsenic in t(6;9)-positive AML

Claudia  Oancea , Brigitte  Rüster , Boris  Brill , Jessica  Roos , Maria  Heinssmann , Gesine  Bug , Afsar Ali Mian , Nathalie Andrea Guillen , Steven M. Kornblau , Reinhard  Henschler , and Martin  Ruthardt

Abstract |  PDF |  Full Text |  Supplementary Material   p378 -392

mTORC2 modulates feedback regulation of p38 MAPK activity via DUSP10/MKP5 to confer differential responses to PP242 in glioblastoma

Angelica  Benavides-Serrato , Lauren  Anderson , Brent  Holmes , Cheri  Cloninger , Nicholas  Artinian , Tariq  Bashir , and Joseph  Gera

Abstract |  PDF |  Full Text |  Supplementary Materials   p393 -406

DEPTOR is linked to a TORC1-p21 survival proliferation pathway in multiple myeloma cells

Yonghui  Yang , Carolyne  Bardeleben , Patrick  Frost , Bao  Hoang , Yijiang  Shi , Richard  Finn , Joseph  Gera , and Alan  Lichtenstein

Abstract |  PDF |  Full Text |  Supplementary Materials   p407 -419

RGS16, a novel p53 and pRb cross-talk candidate inhibits migration and invasion of pancreatic cancer cells

Miranda B. Carper , James  Denvir , Goran  Boskovic , Donald A. Primerano , and Pier Paolo Claudio

Abstract |  PDF |  Full Text |  Supplementary Materials |  Supplementary Materials   p420 -435

Tumor suppression by miR-31 in esophageal carcinoma is p21-dependent

Zhifeng  Ning , Hua  Zhu , Feifei  Li , Qing  Liu , Gefei  Liu , Tao  Tan , Bo  Zhang , Shaobin  Chen , Guanwu  Li , Dongyang  Huang , Stephen J Meltzer , and Hao  Zhang

Abstract |  PDF |  Full Text |  Supplementary Materials   p436 -444

The Bcl-2 inhibitor Obatoclax overcomes resistance to histone deacetylase inhibitors SAHA and LBH589 as radiosensitizers in patient-derived glioblastoma stem-like cells

Lotte M.E. Berghauser Pont , Jochem K.H. Spoor , Subramanian  Venkatesan , Sigrid  Swagemakers Ing , Jenneke J. Kloezeman , Clemens M.F. Dirven , Peter J. van der Spek , Martine L.M. Lamfers , and Sieger  Leenstra

Abstract |  PDF |  Full Text   p445 -459

Taurolidine cooperates with antineoplastic drugs in neuroblastoma cells

Georg  Eschenburg , Christian  Luckert , Konrad  Reinshagen , and Robert   Bergholz

Abstract |  PDF |  Full Text   p460 -469

The antihypertension drug doxazosin suppresses JAK/STATs phosphorylation and enhances the effects of IFN-α/γ-induced apoptosis

Mi  Sun Park , Boh-Ram  Kim , Sokbom   Kang , Dae-Yong  Kim , and Seung  Bae Rho

Abstract |  PDF |  Full Text   p470 -479