Genes & Cancer

Volume 5: Issue 7-8, July 2014

pp226-302

Issue 7-8, July 2014

About the Cover

The cover for Genes & Cancer features figure 1C ("Functional antagonism of TMPRSS2-ERG splice variants in prostate cancer") from Rastogi et al.

Research Papers

PTEN deficiency and mutant p53 confer glucose-addiction to thyroid cancer cells: impact of glucose depletion on cell proliferation, cell survival, autophagy and cell migration

Federica  Morani , Suratchanee  Phadngam , Carlo  Follo , Rossella  Titone , Visa  Thongrakard , Alessandra  Galetto , Oscar  Alabiso , and Ciro  Isidoro

Abstract |  PDF |  Full Text   p226 -239

Impairement of HT29 cancer cells cohesion by the soluble form of neurotensin receptor-3

Fabienne  Massa , Christelle  Devader , Sandra  Lacas-Gervais , Sophie  BĂ©raud-Dufour , Thierry  Coppola , and Jean  Mazella

Abstract |  PDF |  Full Text   p240 -249

CD133-positive cancer stem cells from colo205 human colon adenocarcinoma cell line show resistance to chemotherapy and display a specific metabolomic profile

Zangiacomi  Vincent , Kenichi  Urakami , Koji  Maruyama , Ken  Yamaguchi , and Masatoshi  Kusuhara

Abstract |  PDF |  Full Text |  Supplementary Materials   p250 -260

CDK4/6 inhibition provides a potent adjunct to Her2-targeted therapies in preclinical breast cancer models

Agnieszka K. Witkiewicz , Derek  Cox , and Erik S. Knudsen

Abstract |  PDF |  Full Text   p261 -272

Functional antagonism of TMPRSS2-ERG splice variants in prostate cancer

Anshu  Rastogi , Shyh-Han  Tan , Ahmed A. Mohamed , Yongmei  Chen , Ying  Hu , Gyorgy  Petrovics , Taduru  Sreenath , Jacob  Kagan , Sudhir  Srivastava , David G. McLeod , Isabell A. Sesterhenn , Shiv  Srivastava , Albert  Dobi , and Alagarsamy  Srinivasan

Abstract |  PDF |  Full Text   p273 -284

Impact of DNA repair pathways on the cytotoxicity of piperlongumine in chicken DT40 cell-lines.

Saki  Okamoto , Takeo  Narita , Hiroyuki  Sasanuma , Shunichi  Takeda , Shin-ichiro  Masunaga , Tadayoshi  Bessho , and Keizo  Tano

Abstract |  PDF |  Full Text |  Supplementary Materials   p285 -292

NVP-BEZ-235 enhances radiosensitization via blockade of the PI3K/mTOR pathway in cisplatin-resistant non-small cell lung carcinoma.

Kwang Woon Kim , Carey J. Myers , Dae Kwang Jung , and Bo  Lu

Abstract |  PDF |  Full Text   p293 -302