Genes & Cancer

Volume 10: Issue 1-2, 2019

pp1-51

Issue 1-2, 2019

About the Cover

The cover for the issue of Genes & Cancer features Figure 6 (“Transcriptomic analysis functionally maps the intrinsically disordered domain of EWS/FLI and reveals novel transcriptional dependencies for oncogenesis”) from Theisen et al.

Research Papers

Utilizing cell line-derived organoids to evaluate the efficacy of a novel LIFR-inhibitor, EC359 in targeting pancreatic tumor stroma

https://doi.org/10.18632/genesandcancer.184

Bradley R. Hall , Andrew  Cannon , Christopher  Thompson , Bindu  Santhamma , Alejra  Chavez-Riveros , Rakesh  Bhatia , Hareesh B. Nair , Klaus  Nickisch , Surinder K. Batra , and Sushil  Kumar

p 1-10

Abstract |  PDF |  Full Text |  Supplementary Materials

Targeting RNA helicase DDX3 in stem cell maintenance and teratoma formation

https://doi.org/10.18632/genesandcancer.187

Candace L. Kerr , Guus M. Bol , Farhad  Vesuna , and Venu  Raman

p 11-20

Abstract |  PDF |  Full Text

Transcriptomic analysis functionally maps the intrinsically disordered domain of EWS/FLI and reveals novel transcriptional dependencies for oncogenesis

https://doi.org/10.18632/genesandcancer.188

Emily R. Theisen , Kyle R. Miller , Iftekhar A.  Showpnil , Cenny  Taslim , Kathleen I. Pishas , and Stephen L. Lessnick

p 21-38

Abstract |  PDF |  Full Text |  Supplementary Materials |  Supplementary Materials

Chronic low dose arsenic exposure preferentially perturbs mitotic phase of the cell cycle

https://doi.org/10.18632/genesandcancer.185

Suthakar  Ganapathy , Jian  Liu , Rui  Xiong , Tianqi  Yu , Alexandros  Makriyannis , and Changyan  Chen

p 39-51

Abstract |  PDF |  Full Text